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Personal profile


Dr. Xiaoyu Chen commenced his Research Career at Dept. Med. Chem., Sch. of Pharmacy, Fudan University, China on 2011 under the supervision of Prof. Ying Chen on the design and synthesis of NO-Donor based Anticancer Agents. After obtainied his M.Sc. degree, from 2014 he started to pursue his Ph.D. at CBC, SPMS, Nanyang Technological University, Singapore in the group of Prof. Philip Wai Hong Chan. After about one year’s study, he followed Prof. Chan and moved to Sch. of Chemistry, Faculty of Science, Monash University to continued his research on Gold Catalysis. After thesis submission on Jun-2018, he started to work as a Research Fellow in Dept. Materials Science & Engineering, Faculty of Engineering at the same university in the group of Dr. Hsin-Hui Shen focusing on the development of Polymeric Nanoparticles as Antimicrobial Agents.


Research interests

His current research interest focuses on the development of Antimicrobial Polymeric Nanoparticles as well as Gold and Rhodium Catalysis.

Research area keywords

  • Gold Catalysis
  • Medicinal Chemistry
  • Synthetic Organic Chemistry
  • Antimicrobial agent
  • Nanoparticles
  • Polymers
  • Anticancer Agent
  • Rhodium Catalysis
  • NO Donor

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Research Output 2013 2019

Seco-4-methyl-DCK derivatives as potent chemosensitizers

Guo, Y., Wang, K., Chen, X., Li, H., Wan, Q., Morris-Natschke, S., Lee, K. H. & Chen, Y., 1 Jan 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 1, p. 28-31 4 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Gold-Catalyzed Formal [4 + 2] Cycloaddition of 5-(Ethynylamino)pent-2-yn-1-yl Esters to 1,2,3,5-Tetrahydrobenzo [g] quinolines

Chen, X., Merrett, J. T. & Hong Chan, P. W., 16 Mar 2018, In : Organic Letters. 20, 6, p. 1542-1545 4 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Gold- and Brønsted Acid-Catalyzed Cycloisomerization of 1,8-Diynyl Vinyl Acetates to Bicyclo[2.2.1]hept-2-en-7-ones

Chen, X., Day, D. P., Teo, W. T. & Chan, P. W. H., 18 Nov 2016, In : Organic Letters. 18, 22, p. 5936-5939 4 p.

Research output: Contribution to journalArticleResearchpeer-review

58 Citations (Scopus)

Hybrids of phenylsulfonylfuroxan and coumarin as potent antitumor agents

Liu, M. M., Chen, X. Y., Huang, Y. Q., Feng, P., Guo, Y. L., Yang, G. & Chen, Y., 28 Oct 2014, In : Journal of Medicinal Chemistry. 57, 22, p. 9343-9356 14 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

The regio- and stereo-selective reduction of steroidal 4-en-3-ones using Na2S2O4/NaHCO3 and CuCl/NaBH 4

Wang, C., Chen, X., Huang, Y., Yang, J. & Chen, Y., 6 Nov 2013, In : Steroids. 78, 14, p. 1339-1346 8 p.

Research output: Contribution to journalArticleResearchpeer-review