Projects per year
Collaborations and top research areas from the last five years
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Neutron Reflectometry Insights into Polymyxin-Hexosome Therapy Against Resistant Gram-Negative Bacteria
Shen, H.-H. (Primary Chief Investigator (PCI)), Lai, X. (Chief Investigator (CI)) & Le Brun, A. (Chief Investigator (CI))
12/01/25 → 9/07/25
Project: Research
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Polysaccharide-targeting nanoantibiotics: A new approach to kill Gram-negative superbugs
Shen, H.-H. (Primary Chief Investigator (PCI)), Strugnell, R. A. (Chief Investigator (CI)) & Lai, X. (Chief Investigator (CI))
1/01/24 → 31/12/26
Project: Research
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Reconstitution of lipoteichoic acid – containing Staphylococcus aureus membrane
Shen, H., Lai, X., Wang, S. & Le Brun, A.
10/11/23 → 11/11/23
Project: Research
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Deciphering the dynamic membrane lipid remodelling in Acinetobacter baumannii and the interaction with membrane-targeting peptides
Shen, H.-H. (Primary Chief Investigator (PCI)), Jiang, J.-H. (Chief Investigator (CI)), Lai, X. (Chief Investigator (CI)) & Le Brun, A. (Chief Investigator (CI))
Australian Nuclear Science and Technology Organisation (ANSTO)
9/08/22 → 14/08/22
Project: Research
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Cardiac-targeted delivery of a novel Drp1 inhibitor for acute cardioprotection
Lees, J. G., Greening, D. W., Rudd, D. A., Cross, J., Rosdah, A. A., Lai, X., Lin, T. W., Phang, R. J., Kong, A. M., Deng, Y., Crawford, S., Holien, J. K., Hausenloy, D. J., Shen, H. H. & Lim, S. Y., Sept 2024, In: Journal of Molecular and Cellular Cardiology Plus. 9, 14 p., 100085.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Dissecting the organization of a β-barrel assembly machinery (BAM) complex by neutron reflectometry
Lai, X. & Shen, H. H., 2024, Transmembrane β-Barrel Proteins: Methods and Protocols. Ieva, R. (ed.). New York NY USA: Springer Science + Business Media, Vol. 2778. p. 273-290 18 p. (Methods in Molecular Biology; vol. 2778).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
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Dual recognition of multiple signals in bacterial outer membrane proteins enhances assembly and maintains membrane integrity
Germany, E. M., Thewasano, N., Imai, K., Maruno, Y., Bamert, R. S., Stubenrauch, C. J., Dunstan, R. A., Ding, Y., Nakajima, Y., Lai, X. F., Webb, C. T., Hidaka, K., Tan, K. S., Shen, H., Lithgow, T. & Shiota, T., 16 Jan 2024, In: eLife. 12, 29 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Citations (Scopus) -
Enhanced Nitric Oxide Delivery Through Self-Assembling Nanoparticles for Eradicating Gram-Negative Bacteria
Lai, X., Yu, L., Huang, X., Gardner, W., Bamford, S. E., Pigram, P. J., Wang, S., Brun, A. P. L., Muir, B. W., Song, J., Wang, Y., Hsu, H. Y., Chan, P. W. H. & Shen, H. H., 27 Dec 2024, In: Advanced Healthcare Materials. 13, 32, 15 p., 2403046.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Polysaccharide-targeting lipid nanoparticles to kill gram-negative bacteria
Lai, X., Chow, S. H., Le Brun, A. P., Muir, B. W., Bergen, P. J., White, J., Yu, H. H., Wang, J., Danne, J., Jiang, J. H., Short, F. L., Han, M. L., Strugnell, R. A., Song, J., Cameron, N. R., Peleg, A. Y., Li, J. & Shen, H. H., 8 Feb 2024, In: Small. 20, 6, 13 p., 230502.Research output: Contribution to journal › Article › Research › peer-review
Open Access10 Citations (Scopus)