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Research Output 1989 2019

2012

Efficacy and tolerability of pegylated interferon-alpha-2a in chronic hepatitis B: a multicenter clinical experience

Ratnam, D., Dev, A. T., Nguyen, T., Sundararajan, V., Harley, H., Cheng, W., Lee, A., Rusli, F., Chen, R., Bell, S., Pianko, S. & Sievert, W., 2012, In : Journal of Gastroenterology and Hepatology. 27, 9, p. 1447 - 1453 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Efficacy of entecavir with or without tenofovir disoproxil fumarate for nucleos(t)ide-naive patients with chronic hepatitis B

Lok, A. S., Trinh, H., Carosi, G., Akarca, U. S., Gadano, A., Habersetzer, F., Sievert, W., Wong, D., Lovegren, M., Cohen, D. & Llamoso, C., 2012, In : Gastroenterology. 143, 3 (Art. ID: e1), p. 619 - 628 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Human amniotic epithelial cell transplantation induces markers of alternative macrophage activation and reduces established hepatic fibrosis

Manuelpillai, U. C., Lourensz, D., Vaghjiani, V., Tchongue, J., Lacey, D., Tee, J. Y., Murthi, P., Chan, M. K. J., Hodge, A. & Sievert, W., 2012, In : PLoS ONE. 7, 6, 11 p., e38631.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Long-term safety and tolerability of entecavir in patients with chronic hepatitis B in the rollover study ETV-901

Manns, M. P., Akarca, U. S., Chang, T-T., Sievert, W., Yoon, S. K., Tsai, N., Min, A., Pangerl, A., Beebe, S., Yu, M. & Wongcharatrawee, S., 2012, In : Expert Opinion on Drug Safety. 11, 3, p. 361 - 368 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Natural killer cells display impaired responses to toll like receptor 9 that support viral persistence in chronic hepatitis B

Ratnam, D., Sievert, W. & Visvanathan, K., 2012, In : Cellular Immunology. 279, 1, p. 109 - 115 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Preventing severe chemotherapy-induced reactivation of hepatitis B - Time to adopt a universal approach

Sievert, W., 2012, In : Current Hepatitis Reports. 11, 4, p. 195 - 196 2 p.

Research output: Contribution to journalLetterOther

Protease-activated receptor 2 promotes experimental liver fibrosis in mice and activates human hepatic stellate cells

Knight, V., Tchongue, J., Dowling, D., Tipping, P. & Sievert, W., 2012, In : Hepatology. 55, 3, p. 879 - 887 9 p.

Research output: Contribution to journalArticleResearchpeer-review

STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation

Tye, Y. M. H., Kennedy, C. L., Najdovska, M., McLeod, L., McCormack, W., Hughes, N. R., Dev, A. T., Sievert, W., Ooi, C. H., Ishikawa, T., Oshima, H., Bhathal, P. S., Parker, A. E., Oshima, M., Tan, P. & Jenkins, B. J., 2012, In : Cancer Cell. 22, 4, p. 466 - 478 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2011

An argument for the universal prophylaxis of hepatitis B infection in patients receiving rituximab: A 7-year institutional experience of hepatitis screening

Leung, C., Tsoi, E., Burns, G. & Sievert, W., 2011, In : Oncologist. 16, 5, p. 579 - 584 6 p.

Research output: Contribution to journalArticleResearchpeer-review

A systematic review of hepatitis C virus epidemiology in Asia, Australia and Egypt

Sievert, W., Altraif, I., Razavi, H., Abdo, A., Ahmed, E., AlOmair, A., Amarapurkar, D., Chen, C-H., Dou, X., Khayat, H., elShazly, M., Esmat, G., Guan, R., Han, K-H., Koike, K., Largen, A., McCaughan, G., Mogawer, S., Monis, A., Nawaz, A. & 9 othersPiratvisuth, T., Sanai, F., Sharara, A., Sibbel, S., Sood, A., Suh, D., Wallace, C., Young, K. & Negro, F., 2011, In : Liver International. 31, Supp 2, p. 61 - 80 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of low-level HCV viraemia at week 24 on HCV treatment response in genotype 1 patients

Baleriola, C., Rawlinson, W., Dore, G. J., Chaverot, S., Stelzer-Braid, S., Yoshihara, M., Crawford, D., Sievert, W., McCaughan, G., Weltman, M., Cheng, W., Rizkalla, B., Dubois, D., Thommes, J. & Roberts, S., 2011, In : Antiviral Therapy. 16, 2, p. 173 - 180 8 p.

Research output: Contribution to journalArticleResearchpeer-review

IL28B polymorphism and genetic biomarkers of viral clearance in hepatitis C virus infection

Holmes, J., Sievert, W. & Thompson, A., 2011, In : Biomarkers in Medicine. 5, 4, p. 461 - 478 18 p.

Research output: Contribution to journalArticleOther

Reply

Sievert, W., Dore, G. J. & Roberts, S. K., May 2011, In : Hepatology. 53, 5, p. 1775-1776 2 p.

Research output: Contribution to journalLetterOtherpeer-review

Response

Swan, M. P., Moore, G. T. C., Sievert, W. & Devonshire, D. A., Mar 2011, In : Gastrointestinal Endoscopy. 73, 3, p. 641-642 2 p.

Research output: Contribution to journalLetterOtherpeer-review

Tenofovir disoproxil fumarate rescue therapy following failure of both lamivudine and adefovir dipivoxil in chronic hepatitis B

Patterson, S., George, J., Strasser, S., Lee, A., Sievert, W., Nicoll, A., Desmond, P., Roberts, S., Locarnini, S., Bowden, S. & Angus, P., 2011, In : Gut. 60, 2, p. 247 - 254 8 p.

Research output: Contribution to journalArticleResearchpeer-review

The molecular pathogenesis of STAT3-driven gastric tumourigenesis in mice is independent of IL-17

Kennedy, C., Najdovska, M., Jones, G., McLeod, L., Hughes, N., Allison, C., Ooi, C. H., Tan, P., Ferrero, R., Jones, S., Dev, A., Sievert, W., Bhathal, P. S. & Jenkins, B., 2011, In : Journal of Pathology. 225, 2, p. 255 - 264 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Virological response is associated with decline in hemoglobin concentration during pegylated interferon and ribavirin therapy in hepatitis C virus genotype 1

Sievert, W., Dore, G., McCaughan, G., Yoshihara, M., Crawford, D., Cheng, W., Weltman, M., Rawlinson, W., Rizkalla, B., DePamphilis, J. & Roberts, S., 2011, In : Hepatology. 53, 4, p. 1109 - 1117 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2010

Efficacy and safety of single-session argon plasma coagulation in the management of chronic radiation proctitis

Swan, M., Moore, G., Sievert, W. & Devonshire, D., 2010, In : Gastrointestinal Endoscopy. 72, 1, p. 150 - 154 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Efficacy of entecavir in chronic hepatitis B patients with mildly elevated alanine aminotransferase and biopsy-proven histological damage

Wu, I-C., Lai, C-L., Han, S-H., Han, K-H., Gordon, S., Chao, Y-C., Tan, C-K., Sievert, W., Tanwandee, T., Xu, D., Neo, B-L. & Chang, T-T., 2010, In : Hepatology. 51, 4, p. 1185 - 1189 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Low virological response and high relapse rates in hepatitis C genotype 1 patients with advanced fibrosis despite adequate therapeutic dosing

Cheng, W., Roberts, S., McCaughan, G., Sievert, W., Weltman, M., Crawford, D., Rawlinson, W., Marks, P., Thommes, J., Rizkalla, B., Yoshihara, M. & Dore, G., 2010, In : Journal of Hepatology. 53, 4, p. 616 - 623 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Potential role for interleukin-28B genotype in treatment decision-making in recent hepatitis C virus infection

Grebely, J., Petoumenos, K., Hellard, M., Matthews, G. V., Suppiah, V., Applegate, T., Yeung, B., Marks, P., Rawlinson, W., Lloyd, A. R., Booth, D., Kaldor, J. M., George, J., Dore, G. J., Marks, P., Haber, P. S., Ffrench, R., White, P., Day, C., van Beek, I. & 31 othersMcCaughan, G., Madden, A., Dolan, K., Farrell, G. C., Crofts, N., Sievert, W., Baker, D., Acraman, B., Amin, J., Doab, A., Carroll, T., Nguyen, O., von Bibra, S., Teutsch, S., Li, H., Oon, A., Cameron, B., Jacka, B., Pan, Y., Flynn, J., Goy, K., Shaw, D., Sasadeusz, J., Crawford, D., Phung, N., Bloch, M. T., Hughes, B. M., Mollison, L., Roberts, S., Desmond, P. & ATAHC Study Group, 22 Nov 2010, In : Hepatology. 52, 4, p. 1216-1224 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Transplantation of human amnion epithelial cells reduces hepatic fibrosis in immunocompetent CCl 4-treated mice

Manuelpillai, U., Tchongue, J., Dowling, D., Vaghjiani, V., Samuel, C., Liu, A., Williams, E. & Sievert, W., 2010, In : Cell Transplantation: the regenerative medicine journal. 19, 9, p. 1157 - 1168 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2009

Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat

Lubel, J. S., Herath, C. B., Tchongue, J., Grace, J., Jia, Z., Spencer, K., Casley, D., Crowley, P., Sievert, W., Burrell, L. & Angus, P., 2009, In : Clinical Science. 117, 11, p. 375 - 386 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Antiviral therapy for chronic hepatitis C

Sievert, W., 2009, Hepatitis C: An Expanding Perspective. Dore, G., Temple-Smith, M. & Lloyd, A. (eds.). Australia: IP Communications, p. 192 - 210 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

Impact of high-dose peginterferon alfa-2a on virological response rates in patients with hepatitis C genotype 1: A randomized controlled trial

Roberts, S. K., Weltman, M., Crawford, D., McCaughan, G., Sievert, W., Cheng, W., Rawlinson, W., Desmond, P., Marks, P., Yoshihara, M., Rizkalla, B., DePamphilis, J. & Dore, G., 2009, In : Hepatology. 50, 4, p. 1045 - 1055 11 p.

Research output: Contribution to journalArticleResearchpeer-review

When less may not be best - the challenge of individualising antiviral therapy for chronic hepatitis C infection

Knight, V. H. & Sievert, W., 2009, In : Journal of Gastroenterology and Hepatology. 24, 3, p. 330 - 332 3 p.

Research output: Contribution to journalArticleOther

2008

Erratum: Using natural history to guide managemet of chronic hepatitis B (Medicine Today (2007) (30))

Ratnam, D. & Sievert, W., 1 Jan 2008, In : Medicine Today. 9, 1, 1 p.

Research output: Contribution to journalComment / DebateResearchpeer-review

Long-term efficacy and safety of adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B

Marcellin, P., Chang, T-T., Lim, S. G. L., Sievert, W., Tong, M. J., Arterburn, S., Borroto-Esoda, K., Frederick, D. & Rousseau, F., 2008, In : Hepatology. 48, 3, p. 750 - 758 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2007

Clinical trial: effects of adefovir dipivoxil therapy in Asian and Caucasian patients with chronic hepatitis B

Lim, S. G., Marcellin, P., Tassopoulos, N., Hadziyannis, S., Chang, T., Tong, T., Sievert, W., Hu, P., Arterburn, S. & Brosgart, C. L., 2007, In : Alimentary Pharmacology and Therapeutics. 26, 10, p. 1419 - 1428 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Treatment of hepatitis B e antigen-positive chronic hepatitis with telbivudine or adefovir: A randomized trial

Chan, H. L. Y., Heathcote, J., Marcellin, P., Lai, C-L. L., Cho, M., Moon, Y. S., Chao, Y-C., Myers, R. P., Minuk, G. Y., Jeffers, L., Sievert, W., Bzowej, N., Harb, G., Kaiser, R., Qiao, X-J. & Brown, N. A., 2007, In : Annals of Internal Medicine. 147, 11, p. 745 - 754 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Using natural history to guide management of chronic hepatitis B

Ratnam, D. & Sievert, W., 1 Nov 2007, In : Medicine Today. 8, 11, p. 24-35 12 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2006

Cyanoacrylate in the treatment of gastric varices complicated by multiple pulmonary emboli

Alexander, S. A., Korman, M. G. & Sievert, W., 2006, In : Internal Medicine Journal. 36, 7, p. 462 - 465 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Follistatin attenuates early liver fibrosis: Effects on hepatic stellate cell activation and hepatocyte apoptosis

Patella, S., Phillips, D. J., Tchongue, J., de Kretser, D. M. & Sievert, W., 2006, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 290, 1, p. G137 - G144 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Now, later or never? Challenges associated with hepatitis C treatment

McNally, S., Temple-Smith, M., Sievert, W. & Pitts, M., 2006, In : Australian and New Zealand Journal of Public Health. 30, 5, p. 422 - 427 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2004

Clinical Emergence of Entecavir-Resistant Hepatitis B Virus Requires Additional Substitutions in Virus Already Resistant to Lamivudines

Tenney, D. J., Levine, S. M., Rose, R. E., Walsh, A. W., Weinheimer, S. P., Discotto, L., Plym, M., Pokornowski, K., Yu, C. F., Angus, P. W., Ayres, A., Bartholomeusz, A., Sievert, W., Thompson, G., Warner, N., Locarnini, S. & Colonno, R. J., 2004, In : Antimicrobial Agents and Chemotherapy. 48, 9, p. 3498 - 3507 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Ethnic and cultural determinants influence risk assessment for hepatitis C acquisition

Dev, A. T., Sundararajan, V. & Sievert, W., 2004, In : Journal of Gastroenterology and Hepatology. 19, 7, p. 792 - 798 7 p.

Research output: Contribution to journalArticleResearchpeer-review

The direct cost of managing patients with chronic hepatitis B infection in Australia

Butler, J., Pianko, S., Rosemary, K. J., Nguyen, S., Gow, P., Roberts, S., Strasser, S. I. & Sievert, W., 2004, In : Journal of Clinical Gastroenterology. 38, 10, p. 187 - 192 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2003

Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B

Marcellin, P., Chang, T-T., Lim, S. G., Tong, M. J., Sievert, W., Shiffman, M. L., Jeffers, L., Goodman, Z., Wulfsohn, M. S., Xiong, S., Fry, J. & Brosgart, C. L., 27 Feb 2003, In : New England Journal of Medicine. 348, 9, p. 808-816 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Antiviral therapy for chronic hepatitis C.

Sievert, W., 1 Jan 2003, In : Australian Family Physician. 32, 10, p. 826-832 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Induction interferon and ribavirin for re-treatment of chronic hepatitis C patients unresponsive to interferon alone

Sievert, W., Batey, R., Mollison, L., Pianko, S., McDonald, J., Marinos, G., Reed, W., Warner, S., Bowden, D. S., De Solom, R. & Bhathal, P. S., 2003, In : Alimentary Pharmacology and Therapeutics. 17, 9, p. 1197 - 1204 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2002

Factors associated with severity of hepatic fibrosis in people with chronic hepatitis C infection

Danta, M., Dore, G. J., Hennessy, L., Li, Y., Vickers, C. R., Harley, H., Ngu, M., Reed, W., Desmond, P. V., Sievert, W., Farrell, G. C., Kaldor, J. M. & Batey, R., 2002, In : Medical Journal of Australia. 177, 5, p. 240 - 245 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Fulminant hepatic failure from herpes simplex in pregnancy

Nagappan, R., Parkin, G., Simpson, I. & Sievert, W., 17 Jun 2002, In : Medical Journal of Australia. 176, 12, p. 595-596 2 p.

Research output: Contribution to journalArticleResearchpeer-review

Hepatic iron overload does not prevent a sustained virological response to interferon-α therapy: A long term follow-up study in hepatitis C-infected patients with β thalassemia major

Sievert, W., Pianko, S., Warner, S., Bowden, S., Simpson, I., Bowden, D. & Locarnini, S., 29 Apr 2002, In : American Journal of Gastroenterology. 97, 4, p. 982-987 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Management issues in chronic viral hepatitis: Hepatitis C

Sievert, W., 1 Jan 2002, In : Journal of Gastroenterology and Hepatology (Australia). 17, 4, p. 415-422 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Serum alanine aminotransferase levels and the detection of hepatitis C virus (HCV) in chronic HCV infections

Kelly, H. A., Maskill, W. J., Sievert, W. & Bowden, D. S., 4 Feb 2002, In : Medical Journal of Australia. 176, 3, 1 p.

Research output: Contribution to journalLetterResearchpeer-review

Southeast Asian Patients with Chronic Hepatitis C: The Impact of Novel Genotypes and Race on Treatment Outcome

Dev, A. T., McCaw, R., Sundararajan, V., Bowden, D. S. & Sievert, W., 2002, In : Hepatology. 36, 5, p. 1259 - 1265 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2001

Characterization of serum activin-A and follistatin and their relation to virological and histological determinants in chronic viral hepatitis

Patella, S., Phillips, D. J., de Kretser, D. M., Evans, L. W., Groome, N. P. & Sievert, W., 2001, In : Journal of Hepatology. 34, p. 576 - 583 8 p.

Research output: Contribution to journalArticleResearchpeer-review