William Sievert – Projects — Monash University

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2 Not started
10 Finished
11 Active

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A novel exosome therapy for perianal fistulas occurring in Crohn’s Disease patients
Lim, R., Moore, G., Keung, C. Y. Y., Sievert, W. & Chan, S.
Exosome Biosciences Pty Ltd
1/06/23 → 31/03/25
Project: Research
A Phase 3 Double-blinded, Two-arm Study to Evaluate the Safety and Efficacy of Pembrolizumab (MK-3475) versus Placebo as Adjuvant Therapy in Participants with Hepatocellular Carcinoma and Complete Radiological Response after Surgical Resection of Local Ablation (KEYNOTE-937)
Sievert, W.
5/10/22 → 4/10/27
Project: Research
Locally administered extracellular vesicles for perianal fistulising Crohn's disease
Moore, G., Keung, C. Y. Y., Lim, R., Sievert, W. & Nguyen, T. C.
1/06/21 → 28/02/25
Project: Research
A Phase 3 Multicenter, Randomized, Double-blinded, Active-controlled, Clinical Study to Evaluate the Safety and Efficacy of Lenvatinib (E7080/MK-7902) in Combination with Pembrolizumab (MK-3475) Versus Lenvatinib in First-line Therapy of Participants with Advanced Hepatocellular Carcinoma
Sievert, W.
24/01/20 → 23/01/25
Project: Research
A Phase 2a, randomized, double-blind, placebo-controlled study of oral FXR modulator EYP001a combined with nucleos(t)ide analogues (NA) in virologically suppressed chronic hepatitis B patients to improve functional cure rates
Sievert, W.
20/12/19 → 19/12/24
Project: Research
A Single and Multiple Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AB-729 Administered by Subcutaneous Injection to Healthy Subjects and Subjects with Chronic Hepatitis B Infection
Sievert, W.
16/10/19 → 15/10/24
Project: Research
A Phase 1, Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of single and multiple doses of ABI-H2158 in Healthy Volunteers; and Multiple-Ascending Dose Pharmacokinetics and pharmacodynamics in Patients with Chronic Hepatitis B Infection
Sievert, W.
20/05/19 → 19/05/24
Project: Research
A Three-Part, Phase 1, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of DCR-HBVS in Healthy Volunteers and Patients with Chronic Hepatitis B
Sievert, W.
4/03/19 → 3/03/24
Project: Research
A Phase 1/2, Randomized, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of VIR-2218
Sievert, W.
12/02/19 → 11/02/24
Project: Research
A Phase 1/2a Single Dose-Escalating Study to Evaluate the Safety, Tolerability and Pharmacokinetic Effects of ARO-HBV in Normal Adult Volunteers and Multiple Escalating Doses Evaluating Safety, Tolerability and Pharmacodynamic Effects in HBV Patients
Sievert, W.
1/02/19 → 31/01/24
Project: Research
Monash Breath Laboratory
Sievert, W.
Monash University
1/01/09 → …
Project: Research