William Sievert

Projects

Projects per year 2009 2019 2027

• 2 Not started
• 4 Active
• 17 Finished

Projects per year

Search results

• Active

  A novel exosome therapy for perianal fistulas occurring in Crohn’s Disease patients

  Lim, R., Moore, G., Keung, C., Sievert, W. & Chan, S.

  Exosome Biosciences Pty Ltd

  1/06/23 → 31/03/25

  Project: Research

• A Phase 3 Double-blinded, Two-arm Study to Evaluate the Safety and Efficacy of Pembrolizumab (MK-3475) versus Placebo as Adjuvant Therapy in Participants with Hepatocellular Carcinoma and Complete Radiological Response after Surgical Resection of Local Ablation (KEYNOTE-937)

  Sievert, W.

  5/10/22 → 4/10/27

  Project: Research

• Locally administered extracellular vesicles for perianal fistulising Crohn's disease

  Moore, G., Keung, C., Lim, R., Sievert, W. & Nguyen, T. C.

  1/06/21 → 28/02/26

  Project: Research

• Monash Breath Laboratory

  Sievert, W.

  Monash University

  1/01/09 → …

  Project: Research

• Not started

  Application of follistatin to the resolution of liver fibrosis.

  Phillips, D., Sievert, W. & de Kretser, D.

  National Health and Medical Research Council (NHMRC) (Australia)

  Project: Research

• Therapeutic targeting of JAK-STAT pathway in a novel mouse model for gastro-intestinal cancers

  Jenkins, B., Ernst, M. R. W., Segal, D. H. & Sievert, W.

  Victorian Cancer Agency

  Project: Research

• Finished

  Engineering a solution to non-alcoholic steatohepatitis through tuning substrate stiffness

  Lim, R., Sievert, W., Wallace, E., Frith, J., Greening, D. W. & Kusuma, G.

  1/06/20 → 31/05/22

  Project: Research

• A Phase 3 Multicenter, Randomized, Double-blinded, Active-controlled, Clinical Study to Evaluate the Safety and Efficacy of Lenvatinib (E7080/MK-7902) in Combination with Pembrolizumab (MK-3475) Versus Lenvatinib in First-line Therapy of Participants with Advanced Hepatocellular Carcinoma

  Sievert, W.

  24/01/20 → 23/01/25

  Project: Research

• A Phase 2a, randomized, double-blind, placebo-controlled study of oral FXR modulator EYP001a combined with nucleos(t)ide analogues (NA) in virologically suppressed chronic hepatitis B patients to improve functional cure rates

  Sievert, W.

  20/12/19 → 19/12/24

  Project: Research

• A Single and Multiple Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AB-729 Administered by Subcutaneous Injection to Healthy Subjects and Subjects with Chronic Hepatitis B Infection

  Sievert, W.

  16/10/19 → 15/10/24

  Project: Research

• Using smart technology to more effectively and efficiently monitor the quality of cancer care

  Zalcberg, J., Evans, S., Bain, C., Aleti, A., Mac Manus, C., Brown, W., Sievert, W., Evans, P., Davis, I., Evans, M., Holland, J. & Brand, M.

  Department of Health and Aged Care (Australia)

  1/07/19 → 30/06/21

  Project: Research

• A Phase 1, Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of single and multiple doses of ABI-H2158 in Healthy Volunteers; and Multiple-Ascending Dose Pharmacokinetics and pharmacodynamics in Patients with Chronic Hepatitis B Infection

  Sievert, W.

  20/05/19 → 19/05/24

  Project: Research

• A Three-Part, Phase 1, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of DCR-HBVS in Healthy Volunteers and Patients with Chronic Hepatitis B

  Sievert, W.

  4/03/19 → 3/03/24

  Project: Research

• A Phase 1/2, Randomized, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of VIR-2218

  Sievert, W.

  12/02/19 → 11/02/24

  Project: Research

• A Phase 1/2a Single Dose-Escalating Study to Evaluate the Safety, Tolerability and Pharmacokinetic Effects of ARO-HBV in Normal Adult Volunteers and Multiple Escalating Doses Evaluating Safety, Tolerability and Pharmacodynamic Effects in HBV Patients

  Sievert, W.

  1/02/19 → 31/01/24

  Project: Research

• A spectral and in vitro study of intestinal fibrogenesis and biomarkers in Crohn's disease to inform 3D-human tissue-based models of intestinal fibrosis and identify therapeutic targets

  Keung, C., Moore, G., Lim, R., Sievert, W., Heraud, P. & Wood, B.

  Gutsy Group Inc

  1/01/19 → 31/12/21

  Project: Research

• Development and evaluation of a eHealth 'Virtual Hospital' to improve the care of patients with chronic diseases.

  Liew, D., Sievert, W., Cameron, J., Le, S. T. T., Wang, B., St John, H., Whittle, J., Larkins, A. & Flynn, D.

  1/09/18 → 29/02/20

  Project: Research

• Equipment Grant - HistoIndex Genesis(R)200 Platform

  Samuel, C., Widdop, R., Denton, K., Chin-Dusting, J., Aguilar, M., Wallace, E., Lim, R., Evans, R., Black, M., Ricardo, S., Sievert, W., Dear, A. & Kerr, P.

  3/02/17 → 31/12/17

  Project: Research

• Where have all the stem cells gone? Preliminary in vivo MRI study to track iron-oxide nanoparticle-labelled stem cells

  Lim, R., Jenkin, G., McDonald, C., Bhakoo, K., Sobey, C., Broughton, B., Sievert, W., Vreys, R. & Hodge, A.

  Agilent Technologies (Australia), Monash University – Internal University Contribution

  1/12/14 → 31/12/14

  Project: Research

• When Prometheus needs a hand - how human amnion epithelial cells resolve fibrosis and regenerate the liver

  Sievert, W., Lim, R., Visvanathan, K. & Yeoh, G.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/14 → 31/12/16

  Project: Research

• A study of treatment discontinuation for chronic hepatitis B patients

  Thompson, A., Visvanathan, K., Sievert, W., Desmond, P. V., Locarnini, S. & Sundararajan, V.

  1/01/14 → 31/12/18

  Project: Research

• Donation for Liver Research

  Sievert, W.

  University of Melbourne

  11/02/13 → 31/12/13

  Project: Research

• Role of human amnion epithelial cells in reducing hepatic fibrosis

  Manuelpillai, U. & Sievert, W.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/10 → 31/12/12

  Project: Research