Projects per year
Personal profile
Biography
I obtained my PhD at the University of Otago and held postdoctoral positions at Columbia University, the University of Queensland and the University of Sydney. I am currently a Group Leader in Neuroscience in the Monash Biomedicine Discovery Institute and the Department of Physiology and a NHMRC Career Development Fellow.
Research interests
My research focuses on changes that happen within the pain processing pathways in the spinal cord following the development of chronic pain. Some of these changes are potential therapeutic targets and I am interested in finding new, more effective ways to treat chronic pain.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Pain
- Spinal cord
- Neural circuitry
- Neuropharmacology
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Harnessing Endogenous Opioids to Treat Gut Motility Disorders and Pain
Poole, D., Valant, C., Carbone, S., Mobbs, J., Thal, D., Scammells, P., King, S. K., Imlach, W., Hamilton, J. A. & Veldhuis, N.
1/01/23 → 31/12/26
Project: Research
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Artificial sensory neuron biosensors to predict post-surgical pain
Matusica, D., Barry, C. & Imlach, W.
1/07/22 → 30/06/24
Project: Research
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Development of a nociceptive measuring device capable of differentiating chronic pain states
Matusica, D., Haberberger, R., Tong, T., Magerl, W., Imlach, W., Wiklendt, L., Voelcker, N. & Dinning, P.
1/05/22 → 1/05/25
Project: Research
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Mechanisms of itch - from endosomal signalling to neural circuits
Imlach, W. & De Koninck, Y.
23/06/19 → 1/12/24
Project: Research
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Identifying Novel Molecular Targets for Treating Chronic Pain.
Imlach, W. & De Koninck, Y.
1/01/18 → 31/10/23
Project: Research
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Selective activation of Gαob by an adenosine A1 receptor agonist elicits analgesia without cardiorespiratory depression
Wall, M. J., Hill, E., Huckstepp, R., Barkan, K., Deganutti, G., Leuenberger, M., Preti, B., Winfield, I., Carvalho, S., Suchankova, A., Wei, H., Safitri, D., Huang, X., Imlach, W., La Mache, C., Dean, E., Hume, C., Hayward, S., Oliver, J., Zhao, F-Y., & 5 others, Dec 2022, In: Nature Communications. 13, 1, 22 p., 4150.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus) -
Neuron-specific responses to acetylcholine within the spinal dorsal horn circuits of rodent and primate
Sykes, M. J., Kekesi, O. S., Wong, Y. T., Zhao, F. Y., Spanswick, D. & Imlach, W. L., 15 Oct 2021, In: Neuropharmacology. 198, 12 p., 108755.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia
Draper-Joyce, C. J., Bhola, R., Wang, J., Bhattarai, A., Nguyen, A. T. N., Cowie-Kent, I., O’Sullivan, K., Chia, L. Y., Venugopal, H., Valant, C., Thal, D. M., Wootten, D., Panel, N., Carlsson, J., Christie, M. J., White, P. J., Scammells, P., May, L. T., Sexton, P. M., Danev, R., & 4 others, 23 Sep 2021, In: Nature. 597, p. 571–576 25 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access43 Citations (Scopus) -
A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain
Ramirez Garcia, P. D., Retamal, J. S., Shenoy, P., Imlach, W., Sykes, M., Truong, N., Constandil, L., Pelissier, T., Nowell, C. J., Khor, S. Y., Layani, L. M., Lumb, C., Poole, D. P., Lieu, T., Stewart, G. D., Mai, Q. N., Jensen, D. D., Latorre, R., Scheff, N. N., Schmidt, B. L., & 5 others, Dec 2019, In: Nature Nanotechnology. 14, p. 1150-1159 10 p.Research output: Contribution to journal › Article › Research › peer-review
71 Citations (Scopus) -
Pathological Mechanisms and Therapeutic Targets for Trigeminal Neuropathic Pain
Bista, P. & Imlach, W. L., 22 Aug 2019, In: Medicines. 6, 3, 17 p., 91.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile