• 26 Innovation Walk, Department of Physiology, Building 13F

    3800 Melbourne

    Australia

Accepting PhD Students

20022022
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Personal profile

Biography

I obtained my PhD at the University of Otago and held postdoctoral positions at Columbia University, the University of Queensland and the University of Sydney. I am currently a Group Leader in Neuroscience in the Monash Biomedicine Discovery Institute and the Department of Physiology and a NHMRC Career Development Fellow.

Research interests

My research focuses on changes that happen within the pain processing pathways in the spinal cord following the development of chronic pain. Some of these changes are potential therapeutic targets and I am interested in finding new, more effective ways to treat chronic pain. 

Lab website: https://imlachlab.com/

Publications: https://www.ncbi.nlm.nih.gov/pubmed/?term=wendy+imlach

We are hiring! If you are interested in joining the Pain Mechanisms lab as a Research Officer or Research assistant, please email me and I'll send you more information. We're looking for a candidate with a strong interest in neuroscience who is enthusiastic about learning new techniques to support a range of projects investigating pain at a cellular, circuit and whole animal level. This role may include surgery and rodent behavioral assays, analysis of gene expression and immunohistochemistry. There may also be opportunities to learn basic patch-clamp electrophysiology skills. 

Keywords

  • Pain
  • Spinal cord
  • Neural circuitry
  • Neuropharmacology

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Projects 2017 2022

Research Output 2002 2018

Glycinergic dysfunction in a subpopulation of dorsal horn interneurons in a rat model of neuropathic pain

Imlach, W. L., Bhola, R. F., Mohammadi, S. A. & Christie, M. J., 14 Nov 2016, In : Scientific Reports. 6, 37104.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

An SMN-dependent U12 splicing event essential for motor circuit function

Lotti, F., Imlach, W. L., Saieva, L., Beck, E. S., Hao, L. T., Li, D. K., Jiao, W. W., Mentis, G. Z., Beattie, C. E., McCabe, B. D. & Pellizzoni, L., 12 Oct 2012, In : Cell. 151, 2, p. 440-454 15 p.

Research output: Contribution to journalArticleResearchpeer-review

SMN is required for sensory-motor circuit function in drosophila

Imlach, W. L., Beck, E. S., Choi, B. J., Lotti, F., Pellizzoni, L. & McCabe, B. D., 12 Oct 2012, In : Cell. 151, 2, p. 427-439 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Activity of novel lipid glycine transporter inhibitors on synaptic signalling in the dorsal horn of the spinal cord

Winters, B. L., Rawling, T., Vandenberg, R. J., Christie, M. J., Bhola, R. F. & Imlach, W. L., Jun 2018, In : British Journal of Pharmacology. 175, 12, p. 2337-2347 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission

Yarwood, R. E., Imlach, W. L., Lieu, T., Veldhuis, N. A., Jensen, D. D., Herenbrink, C. K., Aurelio, L., Cai, Z., Christie, M. J., Poole, D. P., Porter, C. J. H., McLean, P., Hicks, G. A., Geppetti, P., Halls, M. L., Canals, M. & Bunnett, N. W., 14 Nov 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 46, p. 12309-12314 6 p.

Research output: Contribution to journalArticleResearchpeer-review