Personal profile

Biography

Dr Wei Yeh is a post-doctoral research fellow in the Department of Neuroscience, School of Translational Medicine, and neurologist in the Multiple Sclerosis and Neuroimmunology (MSNI) Unit, Alfred Health. He is a member of the Multiple Sclerosis Clinical Neuroimmunology research group, led by Professor Helmut Butzkueven. He has a major research interest in understanding clinical and treatment outcomes of multiple sclerosis (MS) and other neuroimmunologic diseases through the use of large observational datasets and translating these findings to inform clinical practice.

His PhD investigated modifiable factors which interact with MS, specifically vitamin D immunobiology, through transcriptomics, and peri-pregnancy disease activity. This research was supported through an Australian Government RTP Scholarship and an MS Australia Postgraduate Scholarship.

His research identified that women with MS with high disease activity before pregnancy, or who had treatment with fingolimod or natalizumab (higher efficacy drugs), had elevated risks for relapse, both within their pregnancy and early post pregnancy. Continuation of natalizumab into pregnancy and early re-initiation shortly thereafter reduced the probabilities for relapse (https://doi.org/10.1212/wnl.0000000000012084). These findings have informed clinical practice and joint decision-making between clinicians and women with MS in the setting of family planning and maintaining MS disease control.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

PhD, Monash University

MBBS, University of Melbourne

BMedSci, University of Melbourne

Research area keywords

  • multiple sclerosis
  • neuroimmunology

Collaborations and top research areas from the last five years

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