Dr Wei Yeh is a post-doctoral research fellow in the Department of Neuroscience, School of Translational Medicine, and neurologist in the Multiple Sclerosis and Neuroimmunology (MSNI) Service, Alfred Health. He is a member of the Multiple Sclerosis Clinical Neuroimmunology research group, led by Professor Helmut Butzkueven. He has a major research interest in understanding clinical and treatment outcomes of multiple sclerosis (MS) and other neuroimmunologic diseases through the use of large observational datasets and translating these findings to inform clinical practice.

His PhD investigated modifiable factors which interact with MS, specifically vitamin D immunobiology, through transcriptomics, and peri-pregnancy disease activity. This research was supported through an Australian Government RTP Scholarship and an MS Australia Postgraduate Scholarship.

His research identified that women with MS with high disease activity before pregnancy, or who had treatment with fingolimod or natalizumab (higher efficacy drugs), had elevated risks for relapse, both within their pregnancy and early post pregnancy. Continuation of natalizumab into pregnancy and early re-initiation shortly thereafter reduced the probabilities for relapse (https://doi.org/10.1212/wnl.0000000000012084). These findings have informed clinical practice and joint decision-making between clinicians and women with MS in the setting of family planning and maintaining MS disease control.

He was recently awarded an ECTRIMS Research Training Fellowship, a competitive and prestigious award from the largest international non-profit organisation for the research of MS and related diseases. He is currently spending time in the Nuffield Department of Clinical Neurosciences, University of Oxford, and John Radcliffe Hospital and investigating treatment outcomes in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) and neuromyelitis optica spectrum disorder (NMOSD) in collaboration with researchers at Monash University, the University of Sydney and other centres.