Projects per year
Personal profile
Biography
I am a researcher in the field of Epigenetics in diabetes and cardiovascular diseases. My latest work identified the role of exercise induced Epigenetic changes associated with reduced oxidative damage and improved micro vascular phenotype in the elderly. My current interest is to understanding the role of epigenetic mechanisms in diabetes associated atherosclerosis.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Epigenetics, PhD, Norepinephrine transporter gene silencing by MeCP2 in postural tachycardia syndrome, University of Melbourne
Award Date: 4 Apr 2017
Research area keywords
- Diabetes
- Epigenetics
- cardiovascular complications of diabetes
- Chromatin
- ncRNA
- Atherosclerosis
Collaborations and top research areas from the last five years
Projects
- 2 Finished
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Role of EZH2 in atherosusceptible vascular endothelium in diabetes associated atherosclerosis
Khan, W. (Primary Chief Investigator (PCI)), Cooper, M. (Chief Investigator (CI)) & Jandeleit-Dahm, K. (Chief Investigator (CI))
1/04/21 → 31/12/21
Project: Research
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Role of histone methyltransferase EZH2 in diabetes associated atherosclerosis
Khan, W. (Primary Chief Investigator (PCI))
1/04/20 → 31/03/22
Project: Research
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Repressive H3K27me3 drives hyperglycemia-induced oxidative and inflammatory transcriptional programs in human endothelium
Sánchez-Ceinos, J., Hussain, S., Khan, A. W., Zhang, L., Almahmeed, W., Pernow, J. & Cosentino, F., 5 Apr 2024, In: Cardiovascular Diabetology. 23, 1, 16 p., 122.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Citations (Scopus) -
Are we ready for cell-specific therapies in atherosclerosis?
Khan, A. W., 21 Aug 2023, In: European Heart Journal. 44, 32, p. 3027-3030 4 p.Research output: Contribution to journal › Article › Other › peer-review
Open Access1 Citation (Scopus) -
Moxonidine Increases Uptake of Oxidised Low-Density Lipoprotein in Cultured Vascular Smooth Muscle Cells and Inhibits Atherosclerosis in Apolipoprotein E-Deficient Mice
Wang, Y., Nguyen, D. T., Anesi, J., Alramahi, A., Witting, P. K., Chai, Z., Khan, A. W., Kelly, J., Denton, K. M. & Golledge, J., Feb 2023, In: International Journal of Molecular Sciences. 24, 4, 15 p., 3857.Research output: Contribution to journal › Article › Research › peer-review
Open Access9 Citations (Scopus) -
Endothelial reactive oxygen-forming NADPH oxidase 5 is a possible player in diabetic aortic aneurysm but not atherosclerosis
Ho, F., Watson, A. M. D., Elbatreek, M. H., Kleikers, P. W. M., Khan, W., Sourris, K. C., Dai, A., Jha, J., Schmidt, H. H. H. W. & Jandeleit-Dahm, K. A. M., Dec 2022, In: Scientific Reports. 12, 1, 10 p., 11570.Research output: Contribution to journal › Article › Research › peer-review
Open Access14 Citations (Scopus) -
Nox5 in Human Peripheral Blood Mononuclear Cells: A Promising Biomarker for Unstable Diabetic Vascular Disease
Block, T. J., Sourris, K. C., Khan, A. W., Kantharidis, P., Jha, J., Cooper, M. E., Shaw, J. A. & Jandeleit-Dahm, K. A. M., Dec 2022, In: American Heart Journal. 254, p. 260 1 p.Research output: Contribution to journal › Meeting Abstract › peer-review
Open Access
Prizes
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Diabetes Wellness Junior Grant for “Role of acetyltransferase GCN5 in endothelial oxidative stress in diabetes
Khan, Waheed (Recipient), 2018
Prize: Other distinction
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Karolinska Institute research Grant “Role of AP-1 transcription factor JunD in diabetes-induced endothelial dysfunction and inflammation
Khan, W. (Recipient), 2018
Prize: Other distinction
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Master’s Scholarship, Faculty development program, University of Balochistan, Pakistan
Khan, Waheed (Recipient), 2009
Prize: Other distinction
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PhD Scholarship: Melbourne International Fee Remission Scholarship (MIFRS)
Khan, W. (Recipient), 2012
Prize: Other distinction
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PhD stipend Scholarship, Baker IDI heart and diabetes Institute, Melbourne, Australia
Khan, W. (Recipient), 2012
Prize: Other distinction