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Research Output 2012 2019

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2019
2 Citations (Scopus)

ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer

Saad, M. I., Alhayyani, S., McLeod, L., Yu, L., Alanazi, M., Deswaerte, V., Tang, K., Jarde, T., Smith, J. A., Prodanovic, Z., Tate, M. D., Balic, J. J., Watkins, D. N., Cain, J. E., Bozinovski, S., Algar, E., Kohmoto, T., Ebi, H., Ferlin, W., Garbers, C. & 4 others, Ruwanpura, S., Sagi, I., Rose-John, S. & Jenkins, B. J., Apr 2019, In : EMBO Molecular Medicine. 11, 4, 19 p., e9976.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2018
8 Citations (Scopus)

Helicobacter pylori type IV secretion system and its adhesin subunit, CagL, mediate potent inflammatory responses in primary human endothelial cells

Tafreshi, M., Guan, J., Gorrell, R. J., Chew, N., Xin, V., Deswaerte, V., Rohde, M., Daly, R. J., Peek Jr, R. M., Jenkins, B. J., Davies, E. M. & Kwok, T., 6 Feb 2018, In : Frontiers in Cellular and Infection Microbiology. 8, FEB, 15 p., 22.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)

Inflammasome adaptor ASC suppresses apoptosis of gastric cancer cells by an IL18-mediated inflammation-independent mechanism

Deswaerte, V., Nguyen, P., West, A., Browning, A. F., Yu, L., Ruwanpura, S. M., Balic, J., Livis, T., Girard, C., Preaudet, A., Oshima, H., Fung, K. Y., Tye, H., Najdovska, M., Ernst, M., Oshima, M., Gabay, C., Putoczki, T. & Jenkins, B. J., 1 Mar 2018, In : Cancer Research. 78, 5, p. 1293-1307 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2017
4 Citations (Scopus)
2016
18 Citations (Scopus)

A CD1d-dependent lipid antagonist to NKT cells ameliorates atherosclerosis in ApoE-/- mice by reducing lesion necrosis and inflammation

Li, Y., Kanellakis, P., Hosseini, H., Cao, A., Deswaerte, V., Tipping, P., Toh, B. H., Bobik, A. & Kyaw, T., 1 Feb 2016, In : Cardiovascular Research. 109, 2, p. 305-317 13 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Low-Density Lipoprotein Receptor-Dependent and Low-Density Lipoprotein Receptor-Independent Mechanisms of Cyclosporin A-Induced Dyslipidemia

Kockx, M., Glaros, E. N., Leung, B., Ng, T. W., Berbée, J. F. P., Deswaerte, V., Nawara, D., Quinn, C., Rye, K-A., Jessup, W., Rensen, P. C. N., Meikle, P. J. & Kritharides, L., 1 Jul 2016, In : Arteriosclerosis, Thrombosis and Vascular Biology. 36, 7, p. 1338-1349 12 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Therapeutic targeting of the IL-6 trans-signaling/mechanistic target of rapamycin complex 1 axis in pulmonary emphysema

Ruwanpura, S. M., McLeod, L., Dousha, L. F., Seow, H. J., Alhayyani, S., Tate, M. D., Deswaerte, V., Brooks, G. D., Bozinovski, S., MacDonald, M., Garbers, C., King, P. T., Bardin, P. G., Vlahos, R., Rose-John, S., Anderson, G. P. & Jenkins, B. J., 15 Dec 2016, In : American Journal of Respiratory and Critical Care Medicine. 194, 12, p. 1494-1505 12 p.

Research output: Contribution to journalArticleResearchpeer-review

File
2015
92 Citations (Scopus)

Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance

Kraakman, M. J., Kammoun, H. L., Allen, T. L., Deswaerte, V., Henstridge, D. C., Estevez, E., Matthews, V. B., Neill, B. A., White, D. A., Murphy, A. J., Peijs, L., Yang, C., Risis, S., Bruce, C. R., Du, X-J., Bobik, A., Lee-Young, R. S., Kingwell, B. A., Vasanthakumar, A., Shi, W. & 4 others, Kallies, A., Lancaster, G. I., Rose-John, S. & Febbraio, M. A., 3 Mar 2015, In : Cell Metabolism. 21, 3, p. 403-416 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
27 Citations (Scopus)

CD4+ natural killer T cells potently augment aortic root atherosclerosis by perforin- and granzyme B-dependent cytotoxicity

Li, Y., To, K., Kanellakis, P., Hosseini, H., Deswaerte, V., Tipping, P. G., Smyth, M. J., Toh, B-H., Bobik, A. & Kyaw, T. S., 2015, In : Circulation Research. 116, 2, p. 245 - 254 10 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Promoting macrophage survival delays progression of pre-existing atherosclerotic lesions through macrophage-derived apoE

Bouchareychas, L., Pirault, J., Saint-Charles, F., Deswaerte, V., Le Roy, T., Jessup, W., Giral, P., Le Goff, W., Huby, T., Gautier, E. L. & Lesnik, P., 21 May 2015, In : Cardiovascular Research. 108, 1, p. 111-123 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2014
39 Citations (Scopus)

Natural killer (NK) cells augment atherosclerosis by cytotoxic-dependent mechanisms

Selathurai, A., Deswaerte, V., Kanellakis, P., Tipping, P. G., Toh, B-H., Bobik, A. & Kyaw, T. S., 2014, In : Cardiovascular Research. 102, 1, p. 128 - 137 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2012
12 Citations (Scopus)

Bcl-x inactivation in macrophages accelerates progression of advanced atherosclerotic lesions in Apoe -/- Mice

Shearn, A. I. U., Deswaerte, V., Gautier, E. L., Saint-Charles, F., Pirault, J., Bouchareychas, L., Rucker, III, E. B., Beliard, S., Chapman, J., Jessup, W., Huby, T. & Lesnik, P., 1 May 2012, In : Arteriosclerosis, Thrombosis and Vascular Biology. 32, 5, p. 1142-1149 8 p.

Research output: Contribution to journalArticleResearchpeer-review