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Research Output 2008 2019

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2019

18F-FDG Metabolic Tumor Volume: Association with Short- and Long-Term Feeding Tube Use in Head and Neck IMRT

Jackson, J. E., Anderson, N. J., Rolfo, M., Wada, M., Schneider, M., Poulsen, M., Fahandej, M., Huynh, A., Lee, S. T., Joon, D. L. & Khoo, V., Jun 2019, In : Dysphagia. 34, 3, p. 341-349 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Fiducial markers: can the urologist do better?

Duncan, C., Joon, D. L., Lawrentschuk, N., Jenkins, T., Schneider, M., Khoo, V., Chao, M., Lawlor, M., O’Meara, R., Berry, C., Viotto, A., Brown, K., Wada, M., Foroudi, F. & Sengupta, S., Jul 2019, In : World Journal of Urology. 37, 7, p. 1281–1287 7 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

High dose rate brachytherapy boost for prostate cancer: Biochemical control and the impact of transurethral resection of the prostate and hydrogel spacer insertion on toxicity outcomes

Chao, M., Bolton, D., Lim Joon, D., Chan, Y., Lawrentschuk, N., Ho, H., Spencer, S., Wasiak, J., Guerrieri, M., Ow, D., Troy, A., Pham, T., Sengupta, S., Tan, A., McMillan, K., Koufogiannis, G., Foroudi, F., Ng, M. & Khoo, V., Jun 2019, In : Journal of Medical Imaging and Radiation Oncology. 63, 3, p. 415–421 7 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

The changing landscape of head and neck cancer radiotherapy patients: is high-risk, prolonged feeding tube use indicative of on-treatment weight loss?

Anderson, N. J., Jackson, J. E., Wada, M., Schneider, M., Poulsen, M., Rolfo, M., Fahandej, M., Gan, H. & Khoo, V., Aug 2019, In : Journal of Medical Radiation Sciences. 66, 4, p. 250-258 9 p.

Research output: Contribution to journalArticleResearchpeer-review

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2018
3 Citations (Scopus)

Pretreatment risk stratification of feeding tube use in patients treated with intensity-modulated radiotherapy for head and neck cancer

Anderson, N. J., Jackson, J. E., Smith, J. G., Wada, M., Schneider, M., Poulsen, M., Rolfo, M., Fahandej, M., Gan, H., Lim Joon, D. & Khoo, V., 1 Oct 2018, In : Head & Neck. 40, 10, p. 2181-2192 12 p.

Research output: Contribution to journalArticleResearchpeer-review

The use of hydrogel spacer in men undergoing high-dose prostate cancer radiotherapy: results of a prospective phase 2 clinical trial

Chao, M., Lim Joon, D., Khoo, V., Lawrentschuk, N., Ho, H., Spencer, S., Chan, Y., Tan, A., Pham, T., Sengupta, S., McMillan, K., Liu, M., Koufogiannis, G., Cham, C. W., Foroudi, F. & Bolton, D., 1 Jan 2018, (Accepted/In press) In : World Journal of Urology. p. 1-6 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2017
3 Citations (Scopus)

An orally bioavailable Chk1 inhibitor, CCT244747, sensitizes bladder and head and neck cancer cell lines to radiation

Patel, R. N., Barker, H. E., Kyula, J. N., McLaughlin, M., Dillon, M. T., Schick, U., Hafsi, H., Thompson, A., Khoo, V., Harrington, K. J. & Zaidi, S., 1 Mar 2017, In : Radiotherapy and Oncology. 122, 3, p. 470-475 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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16 Citations (Scopus)

Clinical Outcomes of Image Guided Adaptive Hypofractionated Weekly Radiation Therapy for Bladder Cancer in Patients Unsuitable for Radical Treatment

Hafeez, S., McDonald, F., Lalondrelle, S., McNair, H., Warren-Oseni, K., Jones, K., Harris, V., Taylor, H., Khoo, V., Thomas, K., Hansen, V., Dearnaley, D., Horwich, A. & Huddart, R., 1 May 2017, In : International Journal of Radiation Oncology Biology Physics. 98, 1, p. 115-122 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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13 Citations (Scopus)

Clinical Outcomes of Perioperative Chemotherapy in Patients With Locally Advanced Penile Squamous-Cell Carcinoma: Results of a Multicenter Analysis

Necchi, A., Pond, G. R., Raggi, D., Ottenhof, S. R., Djajadiningrat, R. S., Horenblas, S., Khoo, V., Hakenberg, O. W., Draeger, D., Protzel, C., Heidenreich, A., Haidl, F., Eigl, B. J., Nappi, L., Matsumoto, K., Vaishampayan, U., Woods, M. E., Salvioni, R., Nicolai, N., Catanzaro, M. & 8 others, Giannatempo, P., Geynisman, D. M., Preto, M., Xylinas, E., Milowsky, M. I., De Placido, S., Di Lorenzo, G. & Sonpavde, G., Oct 2017, In : Clinical Genitourinary Cancer. 15, 5, p. 548-555.e3 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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9 Citations (Scopus)

Effect on Overall Survival of Locoregional Treatment in a Cohort of De Novo Metastatic Prostate Cancer Patients: A Single Institution Retrospective Analysis From the Royal Marsden Hospital

Bianchini, D., Lorente, D., Rescigno, P., Zafeiriou, Z., Psychopaida, E., O'Sullivan, H., Alaras, M., Kolinsky, M., Sumanasuriya, S., Sousa Fontes, M., Mateo, J., Perez Lopez, R., Tunariu, N., Fotiadis, N., Kumar, P., Tree, A., Van As, N., Khoo, V., Parker, C., Eeles, R. & 3 others, Thompson, A., Dearnaley, D. & de Bono, J. S., Oct 2017, In : Clinical Genitourinary Cancer. 15, 5, p. e801-e807 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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15 Citations (Scopus)

Phase 1/2 Dose-Escalation Study of the Use of Intensity Modulated Radiation Therapy to Treat the Prostate and Pelvic Nodes in Patients With Prostate Cancer

Reis Ferreira, M., Khan, A., Thomas, K., Truelove, L., McNair, H., Gao, A., Parker, C., Huddart, R. A., Bidmead, M., Eeles, R., Khoo, V., Van As, N. J., Hansen, V. N. & Dearnaley, D. P., 1 Dec 2017, In : International Journal of Radiation Oncology Biology Physics. 99, 5, p. 1234-1242 9 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

ProCAID: a phase I clinical trial to combine the AKT inhibitor AZD5363 with docetaxel and prednisolone chemotherapy for metastatic castration resistant prostate cancer

Crabb, S. J., Birtle, A. J., Martin, K., Downs, N., Ratcliffe, I., Maishman, T., Ellis, M., Griffiths, G., Thompson, S., Ksiazek, L., Khoo, V. & Jones, R. J., Oct 2017, In : Investigational New Drugs. 35, 5, p. 599-607 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Prostate cancer post-prostatectomy radiotherapy: CT vs MRI for vesico-urethral anastomosis target delineation

Lim Joon, D., Lim, A. Y. L., Schneider, M., Hiew, C-Y., Lawrentschuk, N., Sengupta, S., Foroudi, F., Jenkins, T., Angus, D., Wada, M., Chao, M. & Khoo, V., Oct 2017, In : Radiotherapy and Oncology. 125, 1, p. 113-117 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2016

Clinical management and research priorities for high-risk prostate cancer in the UK: Meeting report of a multidisciplinary panel in conjunction with the NCRI Prostate Cancer Clinical Studies Localised Subgroup

Gnanapragasam, V. J., Hori, S., Johnston, D. T., Smith, D., Muir, K., Alonzi, R., Winkler, M., Warren, A., Staffurth, J., Khoo, V., Tree, A., Macneill, A., McMenemin, R., Mason, M., Cathcart, P., de Souza, N., Sooriakumaran, P., Weston, R., Wylie, J., Hall, E. & 4 others, Lane, A., Cross, W., Syndikus, I. & Koupparis, A., 1 Nov 2016, In : Journal of Clinical Urology. 9, 6, p. 369-379 11 p.

Research output: Contribution to journalArticleResearchpeer-review

334 Citations (Scopus)

Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: 5-year outcomes of the randomised, non-inferiority, phase 3 CHHiP trial

Dearnaley, D. P., Syndikus, I., Mossop, H., Khoo, V., Birtle, A. J., Bloomfield, D., Graham, J., Kirkbride, P., Logue, J., Malik, Z., Money-Kyrle, J., O'Sullivan, J. M., Panades, M., Parker, C., Patterson, H., Scrase, C., Staffurth, J., Stockdale, A., Tremlett, J., Bidmead, M. & 10 others, Mayles, H., Naismith, O., South, C., Gao, A., Cruickshank, C., Hassan, S., Pugh, J., Griffin, C., Hall, E. & on behalf of the CHHiP Investigators, 1 Aug 2016, In : Lancet Oncology. 17, 8, p. 1047-1060 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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24 Citations (Scopus)

Oncolytic vaccinia virus as a vector for therapeutic sodium iodide symporter gene therapy in prostate cancer

Mansfield, DC., Kyula, JN., Rosenfelder, N., Chao-Chu, J., Kramer-Marek, G., Khan, AA., Roulstone, V., McLaughlin, M., Melcher, AA., Vile, RG., Pandha, HS., Khoo, V. & Harrington, KJ., 2016, In : Gene Therapy. 23, 4, p. 357-368 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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10 Citations (Scopus)

The profile feasibility study: Targeted screening of men with a family history of prostate cancer

Castro, E., Mikropoulos, C., Bancroft, E. K., Dadaev, T., Goh, C., Taylor, N. Z., Saunders, E. J., Borley, N., Keating, D., Page, E. C., Saya, S., Hazell, S., Livni, N., Desouza, N., Neal, D., Hamdy, F. C., Kumar, P., Antoniou, A. C., Kote-Jarai, Z., Eeles, R. A. & 13 others, Ardern-Jones, A., Ardern-Jones, P., Van As, N., Dearnaley, D. P., Foster, C., Khoo, V., Lewis, S., Lilja, H., Melia, T. J., Moynihan, C., Pharoah, P. D. P., Sohaib, A. & The Profile Study Steering Committee, 1 Jun 2016, In : Oncologist. 21, 6, p. 716-722 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2015
7 Citations (Scopus)

Comparison of [11C]choline positron emission tomography with T2- and diffusion-weighted magnetic resonance imaging for delineating malignant intraprostatic lesions

Chang, J. H., Lim Joon, D., Davis, I., Lee, S. T., Hiew, C-Y., Esler, S. J., Gong, S. J., Wada, M., Clouston, D., O'Sullivan, R. M., Goh, Y. P., Bolton, D. M., Scott, A. M. & Khoo, V. S., 2015, In : International Journal of Radiation Oncology Biology Physics. 92, 2, p. 438 - 445 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2014
14 Citations (Scopus)

Diffusion-weighted MRI, 11C-choline PET and 18F-fluorodeoxyglucose PET for predicting the Gleason score in prostate carcinoma

Chang, J. H., Lim Joon, D., Lee, S. T., Hiew, C-Y., Esler, S. J., Gong, S. J., Wada, M., Clouston, D., O'Sullivan, R. M., Goh, Y. P., Tochon-Danguy, H., Chan, J. G., Bolton, D. M., Scott, A. M., Khoo, V. S. & Davis, I., 2014, In : European Radiology. 24, 3, p. 715 - 722 8 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Dose-volume response in acute dysphagia toxicity: Validating QUANTEC recommendations into clinical practice for head and neck radiotherapy

Anderson, N. J., Wada, M., Schneider, M. E., Rolfo, M., Lim Joon, D. & Khoo, V. S., 2014, In : Acta Oncologica. 53, 10, p. 1305 - 1311 7 p.

Research output: Contribution to journalArticleResearchpeer-review

207 Citations (Scopus)

Escalated-dose versus control-dose conformal radiotherapy for prostate cancer: Long-term results from the MRC RT01 randomised controlled trial

Dearnaley, D. P., Jovic, G., Syndikus, I., Khoo, V., Cowan, R. A., Graham, J. D., Aird, E. G., Bottomley, D., Huddart, R. A., Jose, C. C., Matthews, J. H. L., Millar, J. L., Murphy, C., Russell, J. M., Scrase, C. D., Parmar, M. K. B. & Sydes, M. R., Apr 2014, In : Lancet Oncology. 15, 4, p. 464-473 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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269 Citations (Scopus)

Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Escudier, B., Porta, C. & Khoo, V. S., 2014, In : Annals of Oncology. 25, Suppl 3, p. 49 - 56 8 p.

Research output: Contribution to journalArticleOther

2012
40 Citations (Scopus)

IMRT dose painting for localized prostate cancer using 11C-choline PET scans.

Chang, J. H., Lim Joon, D., Lee, S. T., Gong, S. J., Anderson, N. J., Scott, A. M., Clouston, D., Davis, I., Bolton, D., Hamilton, C. S. & Khoo, V., 2012, In : International Journal of Radiation Oncology Biology Physics. 83, 4, p. 1 - 6 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2011
33 Citations (Scopus)

Histopathological correlation of 11C-choline PET scans for target volume definition in radical prostate radiotherapy.

Chang, J. H., Lim Joon, D., Lee, S. T., Gong, S. J., Scott, A. M., Davis, I., Clouston, D., Bolton, D., Hamilton, C. S. & Khoo, V., 2011, In : Radiotherapy and Oncology. 99, 2, p. 187 - 192 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2010
25 Citations (Scopus)

Prostate cancer segregation analyses using 4390 families from UK and Australian population-based studies

MacInnis, R., Antoniou, A., Eeles, R., Severi, G., Guy, M., McGuffog, L., Hall, A., O'Brien, L., Wilkinson, R., Dearnaley, D., Arden-Jones, A., Horwich, A., Khoo, V., Parker, C., Huddart, R., McCredie, M., Smith, C., Southey, M., Staples, M., English, D. & 3 others, Hopper, J., Giles, G. & Easton, D., 2010, In : Genetic Epidemiology. 34, 1, p. 42 - 50 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2009
330 Citations (Scopus)

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

Eeles, R. A., Kote-Jarai, Z., Al Olama, A. A., Giles, G. G., Guy, M., Severi, G., Muir, K., Hopper, J. L., Henderson, B. E., Haiman, C. A., Schleutker, J., Hamdy, F. C., Neal, D. E., Donovan, J. L., Stanford, J. L., Ostrander, E. A., Ingles, S. A., John, E. M., Thibodeau, S. N., Schaid, D. & 82 others, Park, J. Y., Spurdle, A., Clements, J., Dickinson, J. L., Maier, C., Vogel, W., Dörk, T., Rebbeck, T. R., Cooney, K. A., Cannon-Albright, L., Chappuis, P. O., Hutter, P., Zeegers, M., Kaneva, R., Zhang, H. W., Lu, Y. J., Foulkes, W. D., English, D. R., Leongamornlert, D. A., Tymrakiewicz, M., Morrison, J., Ardern-Jones, A. T., Hall, A. L., O'Brien, L. T., Wilkinson, R. A., Saunders, E. J., Page, E. C., Sawyer, E. J., Edwards, S. M., Dearnaley, D. P., Horwich, A., Huddart, R. A., Khoo, V. S., Parker, C. C., Van As, N., Woodhouse, C. J., Thompson, A., Christmas, T., Ogden, C., Cooper, C. S., Southey, M. C., Lophatananon, A., Liu, J. F., Kolonel, L. N., Le Marchand, L., Wahlfors, T., Tammela, T. L., Auvinen, A., Lewis, S. J., Cox, A., Fitzgerald, L. M., Koopmeiners, J. S., Karyadi, D. M., Kwon, E. M., Stern, M. C., Corral, R., Joshi, A. D., Shahabi, A., McDonnell, S. K., Sellers, T. A., Pow-Sang, J., Chambers, S., Aitken, J., Gardiner, R. A., Batra, J., Kedda, M. A., Lose, F., Polanowski, A., Patterson, B., Serth, J., Meyer, A., Luedeke, M., Stefflova, K., Ray, A. M., Lange, E. M., Farnham, J., Khan, H., Slavov, C., Mitkova, A., Cao, G., Easton, D. F. & The PRACTICAL consortium, 1 Oct 2009, In : Nature Genetics. 41, 10, p. 1116-1121 6 p.

Research output: Contribution to journalArticleResearchpeer-review

228 Citations (Scopus)

Multiple loci on 8q24 associated with prostate cancer susceptibility

Al Olama, A. A., Kote-Jarai, Z., Giles, G. G., Guy, M., Morrison, J., Severi, G., Leongamornlert, D. A., Tymrakiewicz, M., Jhavar, S., Saunders, E., Hopper, J. L., Southey, M. C., Muir, K. R., English, D. R., Dearnaley, D. P., Ardern-Jones, A. T., Hall, A. L., O'Brien, L. T., Wilkinson, R. A., Sawyer, E. & 15 others, Lophatananon, A., Horwich, A., Huddart, R. A., Khoo, V. S., Parker, C. C., Woodhouse, C. J., Thompson, A., Christmas, T., Ogden, C., Cooper, C., Donovan, J. L., Hamdy, F. C., Neal, D. E., Eeles, R. A. & Easton, D. F., 1 Oct 2009, In : Nature Genetics. 41, 10, p. 1058-1060 3 p.

Research output: Contribution to journalArticleResearchpeer-review

2008
641 Citations (Scopus)

Multiple newly identified loci associated with prostate cancer susceptibility

Eeles, R. A., Kote-Jarai, Z., Giles, G. G., Olama, A. A. A., Guy, M., Jugurnauth, S. K., Mulholland, S., Leongamornlert, D. A., Edwards, S. M., Morrison, J., Field, H. I., Southey, M. C., Severi, G., Donovan, J. L., Hamdy, F. C., Dearnaley, D. P., Muir, K. R., Smith, C., Bagnato, M., Ardern-Jones, A. T. & 26 others, Hall, A. L., O'Brien, L. T., Gehr-Swain, B. N., Wilkinson, R. A., Cox, A., Lewis, S., Brown, P. M., Jhavar, S. G., Tymrakiewicz, M., Lophatananon, A., Bryant, S. L., Horwich, A., Huddart, R. A., Khoo, V. S., Parker, C. C., Woodhouse, C. J., Thompson, A., Christmas, T., Ogden, C., Fisher, C., Jamieson, C., Cooper, C. S., English, D. R., Hopper, J. L., Neal, D. E. & Easton, D. F., 1 Mar 2008, In : Nature Genetics. 40, 3, p. 316-321 6 p.

Research output: Contribution to journalArticleResearchpeer-review