Projects per year
Personal profile
Biography
I am a molecular geneticist interested in the genetic mechanisms of sex determination, sex differentiation, and sex bias in disease.
Education/Academic qualification
Department of Genetics, Bachelor of Science (Hons)
Department of Medicine, Doctor of Philosophy
Research area keywords
- Genomics
- Disease model development
- Sex Determination
- Sex Differences
- Transcription factors
- Parkinson's Disease
- molecular basis of disease
- Genetic risk
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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On the origin of sex differences in gene regulation
Harley, V. (Primary Chief Investigator (PCI)), Landen, S. (Chief Investigator (CI)) & Arnold, A. (Partner Investigator (PI))
ARC - Australian Research Council
24/06/26 → 23/06/29
Project: Research
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A genetic approach to understand sex differences in musculoskeletal ageing
Lamon, S. (Primary Chief Investigator (PCI)), Harley, V. (Chief Investigator (CI)), Eynon, N. (Chief Investigator (CI)), Scott, D. (Chief Investigator (CI)), O'Bryan, S. (Chief Investigator (CI)) & Ziemann, M. (Partner Investigator (PI))
1/09/25 → 31/08/29
Project: Research
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Improving the diagnosis of Differences of Sex Development (DSD)
Harley, V. (Primary Chief Investigator (PCI)), Vilain, E. (Chief Investigator (CI)), Le, T. (Associate Investigator (AI)), Bagheri-Fam, S. (Associate Investigator (AI)), Rosenbluh, S. (Associate Investigator (AI)), Vu, D. C. (Associate Investigator (AI)), Délot, E. C. (Associate Investigator (AI)), Landen, S. (Associate Investigator (AI)) & Reyes, A. (Associate Investigator (AI))
1/01/24 → 31/12/26
Project: Research
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Transformative rat models to study sex differences in disease
Arnold, A. (Primary Chief Investigator (PCI)), Eghbali, M. (Chief Investigator (CI)), Dwinell, M. R. (Chief Investigator (CI)), Geurts, A. (Chief Investigator (CI)), Harley, V. (Chief Investigator (CI)), Sandberg, K. (Chief Investigator (CI)), O'Donnell, L. (Chief Investigator (CI)) & Browne, J. (Chief Investigator (CI))
NIH - National Institutes of Health (United States of America)
15/06/21 → 31/08/26
Project: Research
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SRY antisense oligonucleotide as a gene therapy for males with Parkinson disease
Harley, V. (Primary Chief Investigator (PCI)), Wilton, S. (Chief Investigator (CI)) & Thyagarajan, D. (Chief Investigator (CI))
1/01/22 → 31/12/22
Project: Research
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A role for TRPC3 in mammalian testis development
Ming, Z., Bagheri-Fam, S., Frost, E. R., Ryan, J. M. & Harley, V. R., 2024, In: Frontiers in Cell and Developmental Biology. 12, 11 p., 1337714.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Link opens in a new tab Citations (Scopus) -
Male autism spectrum disorder is linked to brain aromatase disruption by prenatal BPA in multimodal investigations and 10HDA ameliorates the related mouse phenotype
Symeonides, C., Vacy, K., Thomson, S., Tanner, S., Chua, H. K., Dixit, S., Mansell, T., O'Hely, M., Novakovic, B., Herbstman, J. B., Wang, S., Guo, J., Chia, J., Tran, N. T., Hwang, S. E., Britt, K., Chen, F., Kim, T. H., Reid, C. A. & El-Bitar, A. & 17 others, , 7 Aug 2024, In: Nature Communications. 15, 1, 22 p., 6367.Research output: Contribution to journal › Article › Research › peer-review
Open Access48 Link opens in a new tab Citations (Scopus) -
Reprograming skin fibroblasts into Sertoli cells: a patient-specific tool to understand effects of genetic variants on gonadal development
Parivesh, A., Délot, E., Reyes, A., Ryan, J., Bhattacharya, S., Harley, V. & Vilain, E., Dec 2024, In: Biology of Sex Differences. 15, 1, 17 p., 24.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Link opens in a new tab Citations (Scopus) -
Y chromosome damage underlies testicular abnormalities in ATR-X syndrome
León, N. Y., Le, T. N. U., Garvie, A., Wong, L. H., Bagheri-Fam, S. & Harley, V. R., 17 May 2024, In: iScience. 27, 5, 16 p., 109629.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
FGF9 variant in 46,XY DSD patient suggests a role for dimerization in sex determination
Croft, B., Bird, A. D., Ono, M., Eggers, S., Bagheri-Fam, S., Ryan, J. M., Reyes, A. P., van den Bergen, J., Baxendale, A., Thompson, E. M., Kueh, A. J., Stanton, P., Thomas, T., Sinclair, A. H. & Harley, V. R., Mar 2023, In: Clinical Genetics. 103, 3, p. 277-287 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access10 Link opens in a new tab Citations (Scopus)