Projects per year
Personal profile
Biography
Dr Vilija G. Jokubaitis (B. Com/B.Sci (Hons), PhD), is a Senior Research Fellow in the Department of Neuroscience, Central Clinical School at Monash University. She leads the Neuroimmunology Genomics, and Prognostics Group. She is a clinical and translational neuroscientist with skills in molecular medicine and biostatistics. Her research interest lies specifically, in the intersection between biology and clinical outcomes research. The overarching aim of her research is to improve the prediction of Neuroinflammatory disease outcomes (with a focus on MS) in individuals, with the ultimate goal of informing patient management and treatment individualisation.
Research interests
Dr Jokubaitis' research themes fall under three broad umbrellas:
- Women's Health and Pregnancy Research. She leads an international Women's Health, Pregnancy and neonatal outcomes Registry integrated in MSBase (www.msbase.org). This line of enquiry includes elucidating the biological mechanisms underlying pregnancy impacts on disease states.
- Identification of genetic and epigenetic signals associated with disease outcomes, disease states and treatment response.
- Integration of biological (biomarker, genetic) and environmental data with clinical outcomes data to inform prognostic modelling.
Community service
Head of the International Women in MS Mentorship Program https://iwims.world
Monash teaching commitment
Department of Neuroscience and MAPrc, Central Clinical School, Honours Coordinator for BSc and BMS streams
External positions
Honorary Senior Research Fellow, Alfred Health
Feb 2018 → …
Honorary Senior Research Fellow, University of Melbourne
22 Jan 2018 → …
Honorary Research Fellow, Royal Melbourne Hospital
2011 → …
Research area keywords
- Neuroimmunology
- Multiple Sclerosis (MS)
- Central Nervous System
- Women's Health
- Genetics
- Epigenetics
- Biomarkers
- Pharmacogenomics
- Epidemiology
- Outcomes Research
- Biostatistics
- Lifestyle behaviours
Network
-
Determining the risk of cervical precancer and cancer in women with multiple sclerosis: a national data linkage study.
Van Der Walt, A., Jokubaitis, V., Butzkueven, H., Taylor, B. V. M., Lechner-Scott, J. & Brotherton, J. J. M. L.
1/01/22 → 31/12/24
Project: Research
-
Foetal microchimerism: a potential mechanism for long-term pregnancy effects on disability and epigenetic age in multiple sclerosis
Zhong, M. L. X., Jokubaitis, V. & Campagna, M. P.
1/10/21 → 30/09/22
Project: Research
-
Epigenetics of MS progression
Lechner-Scott, J., Maltby, V., Jokubaitis, V. & Lea, R. A.
International Progressive MS Alliance
1/07/21 → 30/06/22
Project: Research
-
Active self-monitoring to prospectively detect treatment failure and define subclinical progression trajectories in multiple sclerosis: The ACTIVE-MS Program.
Van Der Walt, A., Butzkueven, H., Jokubaitis, V., Kolbe, S., Vogel, A. P., Stankovich, J., Butler, E., Macdonell, R. A. L. & Darby, D.
Trish Multiple Sclerosis Research Foundation
1/01/20 → 31/12/22
Project: Research
-
MSPP: Multiple Sclerosis: Pregnancy and Prognosis
Jokubaitis, V., Van Der Walt, A., Hellwig, K., McCombe, P. & Stankovich, J.
1/01/19 → 31/12/22
Project: Research
-
Comparative Effectiveness and Cost-Effectiveness of Natalizumab and Fingolimod in Patients with Inadequate Response to Disease-Modifying Therapies in Relapsing-Remitting Multiple Sclerosis in the United Kingdom
Spelman, T., Herring, W. L., Zhang, Y., Tempest, M., Pearson, I., Freudensprung, U., Acosta, C., Dort, T., Hyde, R., Havrdova, E., Horakova, D., Trojano, M., De Luca, G., Lugaresi, A., Izquierdo, G., Grammond, P., Duquette, P., Alroughani, R., Pucci, E., Granella, F. & 15 others, , Mar 2022, In: PharmacoEconomics. 40, 3, p. 323-339 7 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Prediction of multiple sclerosis outcomes when switching to ocrelizumab
Zhong, M., van der Walt, A., Stankovich, J., Kalincik, T., Buzzard, K., Skibina, O., Boz, C., Hodgkinson, S., Slee, M., Lechner-Scott, J., Macdonell, R., Prevost, J., Kuhle, J., Laureys, G., Van Hijfte, L., Alroughani, R., Kermode, A. G., Butler, E., Barnett, M., Eichau, S. & 12 others, , May 2022, In: Multiple Sclerosis Journal. 28, 6, p. 958-969 12 p.Research output: Contribution to journal › Article › Research › peer-review
-
Effect of Disease-Modifying Therapy on Disability in Relapsing-Remitting Multiple Sclerosis Over 15 Years
Kalincik, T., Diouf, I., Sharmin, S., Malpas, C., Spelman, T., Horakova, D., Havrdova, E. K., Trojano, M., Izquierdo, G., Lugaresi, A., Prat, A., Girard, M., Duquette, P., Grammond, P., Jokubaitis, V., van der Walt, A., Grand'Maison, F., Sola, P., Ferraro, D., Shaygannejad, V. & 40 others, , 2 Feb 2021, In: Neurology. 96, 5, p. e783-e797 15 p.Research output: Contribution to journal › Article › Research › peer-review
13 Citations (Scopus) -
High rates of JCV seroconversion in a large international cohort of natalizumab-treated patients
Dwyer, C. M., Jokubaitis, V. G., Stankovich, J., Baker, J., Haartsen, J., Butzkueven, H., Cartwright, A., Shuey, N., Fragoso, Y. D., Rath, L., Skibina, O., Fryer, K., Butler, E., Coleman, J., MacIntrye, J., Macdonell, R. & Walt, A. V. D., 1 Jan 2021, In: Therapeutic Advances in Neurological Disorders. 14, 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Natalizumab, Fingolimod and Dimethyl Fumarate Use and Pregnancy-Related Relapse and Disability in Women With Multiple Sclerosis
Yeh, W. Z., Widyastuti, P. A., Van Der Walt, A., Stankovich, J., Havrdova, E. K., Horakova, D., Vodehnalova, K., Ozakbas, S., Eichau, S., Duquette, P. P., Kalincik, T., Patti, F., Boz, C., Terzi, M., Yamout, B., Lechner-Scott, J., Sola, P., Skibina, O., Barnett, M., Onofrj, M. & 27 others, , 15 Jun 2021, In: Neurology. 96, 24, p. e2989-e3002 15 p.Research output: Contribution to journal › Article › Research › peer-review
-
Multiple Sclerosis Research Australia (trading as National Multiple Sclerosis Research Foundation Limited) (External organisation)
Vilija Jokubaitis (Member)
Jul 2019 → Jan 2022Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of an advisory panel/policy group/ board
-
PhD Supervision - Dr Ai-Lan Nguyen
Tomas Kalincik (Supervisor), Vilija Jokubaitis (Supervisor), Anneke Van Der Walt (Supervisor) & Helmut Butzkueven (Supervisor)
2017 → 12 May 2021Activity: External Academic Engagement › External HDR Supervision