Victoria Haritos

Assoc Professor

  • 18 Alliance Lane, 36

    3800 Clayton

    Australia

Accepting PhD Students

1993 …2019
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Personal profile

Biography

Broadly my research brings together biology and engineering to address future manufacturing needs.

I am interested in discovering and designing enzymes for specific and fast reactions as isolated biocatalysts. In addition, I'm researching the metabolic and systems biology of cells in culture - examining productivity and underlying reasons behind heterogeneity in response and how this can be modified - using our high throughput culture and single cell analysis facility.

I use biocatalysts at different scales; the simplest scale being the isolated enzyme to the most complex such as a self-replicating cell. Each approach has their benefits and disadvantages. The easiest to implement is an isolated biocatalysts but these have limited capacity for product formation and processing. At the other extreme, whole cells have complex biochemical pathways to consider and require approaches like metabolic engineering or synthetic biology to streamline and improve production of selected metabolites.

Also, we're applying research knowledge to improve thermal processing outcomes and preserving nutrients in processed foods by working with a range of food and beverage companies. In a different direction, we are using yeast to convert food wastes and byproducts to biodiesel production.

Research interests

Enzyme discovery and design; metabolic engineering of yeast and bacteria; systems biology of cultured cells.

 

Application areas: biocatalysis; bioprocessing; energy

Monash teaching commitment

  • CHE1010 Grand Challenges in Chemical Engineering: delivering sustainable water, food and energy
  • CHE4180 Research project
  • CHE4171 Biochemical engineering
  • CHE5882 Biomass and biorefineries
  • CHE5889 Food Engineering

Supervision interests

Final year (CHE4180) students; PhD students interested in these research areas are welcome to apply

Research area keywords

  • Enzymes
  • metabolic engineering
  • cell heterogeneity
  • Lipid metabolism
  • synthetic biology
  • Protein engineering

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Projects 2018 2019

Research Output 1993 2019

Beneath the surface: evolution of methane activity in the bacterial multicomponent monooxygenases

Osborne, C. D. & Haritos, V. S., 1 Oct 2019, In : Molecular Phylogenetics and Evolution. 139, 12 p., 106527.

Research output: Contribution to journalArticleResearchpeer-review

Effect of refining and homogenization on nanocellulose fiber development, sheet strength and energy consumption

Ang, S., Haritos, V. & Batchelor, W., 1 May 2019, In : Cellulose. 26, 8, p. 4767-4786 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Enhanced production of high-value cyclopropane fatty acid in yeast engineered for increased lipid synthesis and accumulation

Peng, H., He, L. & Haritos, V. S., Apr 2019, In : Biotechnology Journal. 14, 4, 5 p., 1800487.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Raman spectroscopy as a tool for tracking cyclopropane fatty acids in genetically engineered: Saccharomyces cerevisiae

Kochan, K., Peng, H., Gwee, E. S. H., Izgorodina, E., Haritos, V. & Wood, B. R., 7 Feb 2019, In : Analyst. 144, 3, p. 901-912 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Prizes

Finalist for Ichem Biotechnology global awards 2016

Lizhong He (Recipient), Bhuvana Shanbhag (Recipient) & Victoria Haritos (Recipient), 2016

Prize: Prize (including medals and awards)

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