Projects per year
Personal profile
Biography
Broadly my research brings together biology and engineering to address sustainable manufacturing.
I am interested in discovering and designing enzymes for specific and fast reactions and applied as biocatalysts for use in vitro and in vivo. Also I research the metabolic and systems biology of yeast and bacterial cells in culture, examining the exometabolome and recombinant production of proteins and investigating heterogeneity among cells using our high throughput culture and single cell analysis facility.
I use biocatalysts at different scales; the simplest scale being the isolated enzyme to the most complex such as a self-replicating cell. The easiest to implement is an isolated enzymes (biocatalysts) for application in cellulose and food processing through to cascade/tandem reaction systems. At the other extreme, whole cells have complex biochemical pathways to consider and require approaches like synthetic biology to streamline and improve production of selected metabolites.
Also, I have an active research program in food processing supported by industry projects with particular interest in polyphenol antioxidants, dietary fibres and valorising food byproducts.
For more information go to my group site at https://sites.google.com/monash.edu/haritos-group/home
Research interests
Enzyme discovery and design; synthetic biology of yeast and bacteria for bioproduction; food byproduct valorisation
Application areas: biocatalysis; bioprocessing; fermentation
Monash teaching commitment
- CHE5322 Advanced Biochemical Technology
- CHE5321 Advanced Bioprocess Engineering
- ENG4701 and ENG4702 Research Project
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Enzymes
- cell heterogeneity
- Biocatalysis
- synthetic biology
- Protein engineering
- Food byproduct
Collaborations and top research areas from the last five years
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ARC Research Hub for Processing Lignocellulosics into High Value Products
Garnier, G., Batchelor, W., Simon, G., Haritos, V., Patti, A., Saito, K., Griesser, H., Paull, B., Tanner, J., Spinnler, H., Allais, F., Richardson, D., Mackay, A., Carter, S., Faltas, R., Edye, L., Hendriks, D., Karmakar, N. & Bhattacharya, S.
Monash University – Internal University Contribution, Monash University – Internal Faculty Contribution, Monash University – Internal Department Contribution, Paper Australia Pty Ltd, Leaf Resources Pty Ltd, Department of State Growth (Tasmania), University of Tasmania, University of South Australia, URD Agro Biotechnologies Industrielles, Visy Industries Australia Pty Ltd (trading as Visy Industries), Norske Skog Paper Mills (Australia) Pty Ltd, Orora Limited (trading as AMCOR Australia)
10/01/18 → 31/12/24
Project: Research
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Optimisation of behind the meter DER generation assets within network constraints: A roadmap to successful DR program
Jalili, M., Hasan, K., Yu, X., McGrath, B., Meegahapola, L., Salim, F. D., Liebman, A., Razzaghi, R. & Haritos, V.
AGL Energy Limited, Centre for New Energy Technologies (C4NET), Renewable Baseload Generation
12/10/21 → 20/06/23
Project: Research
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Feasibility Study - Valorisation of Stone Fruit Waste
Patti, A., Haritos, V. & Avendano, E.
13/08/21 → 21/03/22
Project: Research
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Enzymatic production of cello-oligosaccharides with potential human prebiotic activity and release of polyphenols from grape marc
Liu, X., Hu, K. K. Y. & Haritos, V. S., 1 Mar 2024, In: Food Chemistry. 435, 10 p., 137562.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Modulating the hydrophobicity of cellulose by lipase-catalyzed transesterification
Sharma, R., Putera, K. H., Banaszak Holl, M. M., Garnier, G. & Haritos, V. S., Jan 2024, In: International Journal of Biological Macromolecules. 254, 9 p., 127972.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Spatially confined enzymatic tandem system with GOx and HRP compartmentalized in ultrafiltration membrane
Barricella, S., Fuertes, J. M., Putera, K. H., Quigley, A. E., Haritos, V., Freeman, B. D. & Garnier, G., 15 Jan 2024, In: Journal of Membrane Science. 690, 11 p., 122214.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Analysis of the fate of valuable bioactive polyphenols during commercial winemaking and their partitioning into wastes for valorization
Liu, X., Robinson, A. L., Jarratt, G. & Haritos, V. S., Aug 2023, In: Cleaner Waste Systems. 5, 10 p., 100104.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
An ultrastable self-assembled antibacterial nanospears made of protein
Dzuvor, C. K. O., Shanbhag, B. K., Shen, H-H., Haritos, V. S. & He, L., 27 Jul 2023, In: Advanced Materials. 35, 30, 11 p., 2302409.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus)
Prizes
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Finalist for Ichem Biotechnology global awards 2016
He, Lizhong (Recipient), Shanbhag, Bhuvana (Recipient) & Haritos, Victoria (Recipient), 2016
Prize: Prize (including medals and awards)
File
Press/Media
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Article featured online on Advances in Engineering (https://advanceseng.com/ )
Lizhong He, Bhuvana Shanbhag & Victoria Haritos
24/01/19
1 item of Media coverage
Press/Media: Research