Projects per year
Personal profile
Biography
Broadly my research brings together biology and engineering to address future manufacturing needs.
I am interested in discovering and designing enzymes for specific and fast reactions as isolated biocatalysts. In addition, I'm researching the metabolic and systems biology of cells in culture - examining productivity and underlying reasons behind heterogeneity in response and how this can be modified - using our recently installed high throughput culture and single cell analysis facility.
I use biocatalysts at different scales; the simplest scale being the isolated enzyme to the most complex such as a self-replicating cell. Each approach has their benefits and disadvantages. The cheapest and easiest to implement is an isolated biocatalysts but these have limited capacity for product formation and processing. At the other extreme, whole cells have complex biochemical pathways to consider and require approaches like metabolic engineering or synthetic biology to streamline and improve production of selected metabolites.
Research interests
Enzyme discovery and design; metabolic engineering of yeast and bacteria; systems biology of cultured cells.
Application areas: biocatalysis; bioprocessing; manufacturing; energy
Monash teaching commitment
- CHE4180 Research project
- CHE4171 Biochemical engineering
- CHE5882 Biomass and biorefineries
Supervision interests
Final year (CHE4180) students; PhD students interested in these research areas are welcome to apply
Keywords
- Enzymes
- biocatalysis
- systems biology
- metabolic engineering
- synthetic biology
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 1993 2018
Enhanced Production of High-Value Cyclopropane Fatty Acid in Yeast Engineered for Increased Lipid Synthesis and Accumulation
Peng, H., He, L. & Haritos, V. S., 8 Oct 2018, (Accepted/In press) In : Biotechnology Journal. 5 p.Research output: Contribution to journal › Article › Research › peer-review
Functional assessment of plant and microalgal lipid pathway genes in yeast to enhance microbial industrial oil production
Peng, H., Moghaddam, L., Brinin, A., Williams, B., Mundree, S. & Haritos, V. S., 1 Mar 2018, In : Biotechnology and Applied Biochemistry. 65, 2, p. 138-144 7 p.Research output: Contribution to journal › Article › Research › peer-review
Horizontal gene transfer of three co-inherited methane monooxygenase systems gave rise to methanotrophy in the Proteobacteria
Osborne, C. D. & Haritos, V. S., 1 Dec 2018, In : Molecular Phylogenetics and Evolution. 129, p. 171-181 11 p.Research output: Contribution to journal › Article › Research › peer-review
Metabolic engineering of lipid pathways in Saccharomyces cerevisiae and staged bioprocess for enhanced lipid production and cellular physiology
Peng, H., He, L. & Haritos, V. S., 1 Aug 2018, In : Journal of Industrial Microbiology & Biotechnology. 45, 8, p. 707-717 11 p.Research output: Contribution to journal › Article › Research › peer-review
Microwave assisted pretreatment of eucalyptus sawdust enhances enzymatic saccharification and maximizes fermentable sugar yield
Amini, N., Haritos, V. S. & Tanksale, A., 1 Nov 2018, In : Renewable Energy. 127, p. 653-660 8 p.Research output: Contribution to journal › Article › Research › peer-review