Personal profile

Biography

Broadly my research brings together biology and engineering to address future manufacturing needs.

I am interested in discovering and designing enzymes for specific and fast reactions as isolated biocatalysts. In addition, I'm researching the systems biology of cells in culture - the underlying reasons behind their heterogeneity and how this can be modified - using our recently installed high throughput culture and single cell analysis facility.

 

I use biocatalysts at different scales; the simplest scale being the isolated enzyme to the most complex such as a self-replicating cell. Each approach has their benefits and disadvantages. The cheapest and easiest to implement is an isolated biocatalysts but these have limited capacity for product formation and processing. At the other extreme, whole cells have complex biochemical pathways to consider and require approaches like metabolic engineering or synthetic biology to streamline and improve production of selected metabolites.

Research interests

Enzyme discovery and design; metabolic engineering of yeast and bacteria; systems biology of cultured cells.

 

Application areas: biocatalysis; bioprocessing; manufacturing; energy

Monash teaching commitment

  • CHE4180 Research project
  • CHE4171 Biochemical engineering
  • CHE5882 Biomass and biorefineries

Supervision interests

Supervisor for: 

Cameron Hunt

Associate Supervisor

Enrolled: Doctorate by Research

Project title: Novel enzymes in the deconstruction of lignocellulosic biomass

Supervisor 25%

1/01/13 → …

Negin Amini

Associate Supervisor

Enrolled: Doctorate by Research

Project title: Biomass pre-treatment and separation for fuels and chemicals production

Supervisor 25%

1/07/14 → …

Pradeep G C

Associate Supervisor

Enrolled: Doctorate by Research

Project title: Engineering robust enzyme nano-complexes for simultaneous capture and conversion of CO2 into sustainable fuel

Supervisor 20%

1/07/14 → …

Melissa Mace

Main Supervisor (Principal Supervisor)

Enrolled: Doctorate by Research

Project title: Production of high value oleochemicals using cyclopropane fatty acid synthase biocatalysts

Supervisor 75%

1/01/15 → …

Huadong Peng

Main Supervisor (Principal Supervisor)

Enrolled: Doctorate by Research

Project title: Novel lipid accumulation and sequestration pathways in Saccharomyces cerevisae for production of fuels and chemicals feedstocks

Supervisor 50%

1/01/15 → …

Teck Wei Ching

Associate Supervisor

Discontinued: Masters by Research

Project title: Material segregation phenomenon in spray dried particles

Supervisor 25%

1/01/13 → 16/07/14

Teck Wei Ching

Associate Supervisor

Enrolled: Doctorate by Research

Project title: Material segregation phenomenon in spray dried particles

Supervisor 25%

1/07/14 → …

Jamie Joseph Castillo

Associate Supervisor

Enrolled: Doctorate by Research

Project title: Research proposal is currently in negotiation with partners of the Chemicals and Plastics Innovation

Supervisor 40%

1/01/15 → …

Craig David Osborne

Main Supervisor (Principal Supervisor)

Enrolled: Doctorate by Research

Project title: Rational biocatalyst design and engineering for the activation of alkanes to higher value products

Supervisor 50%

1/01/15 → …

Shaun Ang

Associate Supervisor

Enrolled: Doctorate by Research

Project title: New Functional Printed or Coated Materials Based on Cellulose Nanofibres

Supervisor 50%

1/01/16 → …

Bhuvana Kamath Shanbhag

Associate Supervisor

Enrolled: Doctorate by Research

Project title: Bioremediation of Heavy metal effluent using diatom biofilms

Supervisor 25%

1/07/13 → …

Habtewold Deti Waktola

Associate Supervisor

Enrolled: Doctorate by Research

Project title: Olive Oil Fatty acid Profiling Using Multidimensional Gas Chromatography.

Supervisor 10%

1/07/16 → …

 

Keywords

  • Enzymes
  • biocatalysis
  • systems biology
  • metabolic engineering
  • synthetic biology

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1993 2017

Functional assessment of plant and microalgal lipid pathway genes in yeast to enhance microbial industrial oil production

Peng, H., Moghaddam, L., Brinin, A., Williams, B., Mundree, S. & Haritos, V. S. 2017 (Accepted/In press) In : Biotechnology and Applied Biochemistry. p. 1-7 7 p.

Research output: Research - peer-reviewArticle

Insights into substrate binding of ferulic acid esterases by arabinose and methyl hydroxycinnamate esters and molecular docking

Hunt, C. J., Antonopoulou, I., Tanksale, A., Rova, U., Christakopoulos , P. & Haritos, V. S. 11 Dec 2017 In : Scientific Reports. 7, 11 p., 17315

Research output: Research - peer-reviewArticle

Open Access
File

Microwave assisted conversion of microcrystalline cellulose into value added chemicals using dilute acid test

Ching, T. W., Haritos, V. & Tanksale, A. 10 Feb 2017 In : Carbohydrate Polymers. 157, p. 1794-1800 7 p.

Research output: Research - peer-reviewArticle

Levulinic acid as a catalyst for the production of 5-hydroxymethylfurfural and furfural from lignocellulose biomass

Seemala, B., Haritos, V. & Tanksale, A. 2016 In : ChemCatChem. 8, 3, p. 640 - 647 8 p.

Research output: Research - peer-reviewArticle

Activities 2014 2014

  • 1 Submissions to industry or govt committees, commissions and inquiries

Faculty of Engineering

Haritos, V. (Member)
6 Oct 20146 Oct 2017

Activity: Submissions to industry or govt committees, commissions and inquiries