Tu Nguyen

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Tu Nguyen

Dr

 https://orcid.org/0000-0002-6217-0182

  • Level 7, TRF Building
    Monash Medical Centre
    246 Clayton Road, Clayton VIC 3168

    Australia

Accepting PhD Students

PhD projects

<a href="https://www.monash.edu/medicine/research/supervisorconnect" onclick="target='_blank';">https://www.monash.edu/medicine/research/supervisorconnect</a>

20082023

Research activity per year

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Personal profile

Biography

Dr Tu Nguyen-Dumont is a molecular biologist, cancer genomicist and bioinformatician. She is Head of the Clinical Genomics Laboratory, Precision Medicine, Monash University and a Victorian Cancer Agency Mid-career Research Fellow (2022-2026). She is an Honorary Research Fellow in the Department of Clinical Pathology, The University of Melbourne Centre for Cancer Research.

Tu was awarded a PhD in 2010 from University Claude Bernard, Lyon, France. She completed her PhD training in the Genetic Cancer Susceptibility group at the International Agency for Research on Cancer/World Health Organization (IARC/WHO, France), during which she received a PhD scholarship from Fondation de France and a Special Trainee Award from IARC/WHO. In 2011, she was awarded a Komen Foundation Postdoctoral Fellowship, which allowed her to gain international research experience by moving to Melbourne and training at the Genetic Epidemiology Laboratory, The University of Melbourne.

In 2017, she received a National Breast Cancer Foundation Career Development Fellowship (2017-2021). She was appointed Senior Research Fellow in the Precision Medicine group, School of Clinical Sciences at Monash Health, Monash University.

She is the genomics and bioinformatics lead of several large-scale, multi-disciplinary international research studies that are advancing our understanding of cancer risk and impacting the effectiveness of cancer prevention and early detection.

 

Research interests

Tu and her team use cutting-edge molecular techniques and bioinformatics to understand the underlying causes of genetic predisposition to breast, prostate and paediatric cancers.

Her training and expertise puts her in a unique position in the "research and translation" space. She believes that translational bioinformatics will enable to fully realise the biological and clinical value of the vast amount of data that is currently being generated.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Molecular biology-Oncogenetics, PhD, Université Claude Bernard Lyon 1 (University Claude Bernard Lyon 1)

Award Date: 15 Dec 2010

External positions

Honorary Research Fellow, University of Melbourne

1 Jul 2017 → 30 Jun 2027

Network

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  • Heritable methylation marks associated with prostate cancer risk

    Dowty, J. G., Yu, C., Hosseinpour, M., Joo, J. E., Wong, E. M., Nguyen-Dumont, T., Rosenbluh, J., Giles, G. G., Milne, R. L., MacInnis, R. J., Dugué, P. A. & Southey, M. C., 2023, (Accepted/In press) In: Familial Cancer. 5 p.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access

  • Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores

    Barnes, D. R., Silvestri, V., Leslie, G., McGuffog, L., Dennis, J., Yang, X., Adlard, J., Agnarsson, B. A., Ahmed, M., Aittomaki, K., Andrulis, I. L., Arason, A., Arnold, N., Auber, B., Azzollini, J., Balmana, J., Barkardottir, R. B., Barrowdale, D., Barwell, J., Belotti, M., & 145 othersBenitez, J., Berthet, P., Boonen, S. E., Borg, A., Bozsik, A., Brady, A. F., Brennan, P., Brewer, C., Brunet, J., Bucalo, A., Buys, S. S., Caldes, T., Caligo, M. A., Campbell, I., Cassingham, H., Christensen, L. L., Cini, G., Claes, K. B. M., Cook, J., Coppa, A., Cortesi, L., Damante, G., Darder, E., Davidson, R., De La Hoya, M., De Leeneer, K., De Putter, R., Del Valle, J., Diez, O., Ding, Y. C., Domchek, S. M., Donaldson, A., Eason, J., Eeles, R., Engel, C., Evans, D. G., Feliubadalo, L., Fostira, F., Frone, M., Frost, D., Gallagher, D., Gehrig, A., Giraud, S., Glendon, G., Godwin, A. K., Goldgar, D. E., Greene, M. H., Gregory, H., Gross, E., Hahnen, E., Hamann, U., Hansen, T. V. O., Hanson, H., Hentschel, J., Horvath, J., Izatt, L., Izquierdo, A., James, P. A., Janavicius, R., Jensen, U. B., Johannsson, O. T., John, E. M., Kramer, G., Kroeldrup, L., Kruse, T. A., Lautrup, C., Lazaro, C., Lesueur, F., Lopez-Fernandez, A., Mai, P. L., Manoukian, S., Matrai, Z., Matricardi, L., Maxwell, K. N., Mebirouk, N., Meindl, A., Montagna, M., Monteiro, A. N., Morrison, P. J., Muranen, T. A., Murray, A., Nathanson, K. L., Neuhausen, S. L., Nevanlinna, H., Nguyen-Dumont, T., Niederacher, D., Olah, E., Olopade, O. I., Palli, D., Parsons, M. T., Pedersen, I. S., Peissel, B., Perez-Segura, P., Peterlongo, P., Petersen, A. H., Pinto, P., Porteous, M. E., Pottinger, C., Pujana, M. A., Radice, P., Ramser, J., Rantala, J., Robson, M., Rogers, M. T., Rønlund, K., Rump, A., Sanchez De Abajo, A. M., Shah, P. D., Sharif, S., Side, L. E., Singer, C. F., Stadler, Z., Steele, L., Stoppa-Lyonnet, D., Sutter, C., Tan, Y. Y., Teixeira, M. R., Teule, A., Thull, D. L., Tischkowitz, M., Toland, A. E., Tommasi, S., Toss, A., Trainer, A. H., Tripathi, V., Valentini, V., Van Asperen, C. J., Venturelli, M., Viel, A., Vijai, J., Walker, L., Wang-Gohrke, S., Wappenschmidt, B., Whaite, A., Zanna, I., Offit, K., Thomassen, M., Couch, F. J., Schmutzler, R. K., Simard, J., Easton, D. F., Chenevix-Trench, G., Antoniou, A. C., Ottini, L. & on behalf of the Consortium of Investigators of Modifiers of BRCA1 and BRCA2, Jan 2022, In: Journal of the National Cancer Institute. 114, 1, p. 109-122 14 p.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    10 Citations (Scopus)

  • Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers

    Hakkaart, C., Pearson, J. F., Marquart, L., Dennis, J., Wiggins, G. A. R., Barnes, D. R., Robinson, B. A., Mace, P. D., Aittomäki, K., Andrulis, I. L., Arun, B. K., Azzollini, J., Balmaña, J., Barkardottir, R. B., Belhadj, S., Berger, L., Blok, M. J., Boonen, S. E., Borde, J., Bradbury, A. R., & 146 othersBrunet, J., Buys, S. S., Caligo, M. A., Campbell, I., Chung, W. K., Claes, K. B. M., Collonge-Rame, M. A., Cook, J., Cosgrove, C., Couch, F. J., Daly, M. B., Dandiker, S., Davidson, R., de la Hoya, M., de Putter, R., Delnatte, C., Dhawan, M., Diez, O., Ding, Y. C., Domchek, S. M., Donaldson, A., Eason, J., Easton, D. F., Ehrencrona, H., Engel, C., Evans, D. G., Faust, U., Feliubadaló, L., Fostira, F., Friedman, E., Frone, M., Frost, D., Garber, J., Gayther, S. A., Gehrig, A., Gesta, P., Godwin, A. K., Goldgar, D. E., Greene, M. H., Hahnen, E., Hake, C. R., Hamann, U., Hansen, T. V. O., Hauke, J., Hentschel, J., Herold, N., Honisch, E., Hulick, P. J., Imyanitov, E. N., Isaacs, C., Izatt, L., Izquierdo, A., Jakubowska, A., James, P. A., Janavicius, R., John, E. M., Joseph, V., Karlan, B. Y., Kemp, Z., Kirk, J., Konstantopoulou, I., Koudijs, M., Kwong, A., Laitman, Y., Lalloo, F., Lasset, C., Lautrup, C., Lazaro, C., Legrand, C., Leslie, G., Lesueur, F., Mai, P. L., Manoukian, S., Mari, V., Martens, J. W. M., McGuffog, L., Mebirouk, N., Meindl, A., Miller, A., Montagna, M., Moserle, L., Mouret-Fourme, E., Musgrave, H., Nambot, S., Nathanson, K. L., Neuhausen, S. L., Nevanlinna, H., Yie, J. N. Y., Nguyen-Dumont, T., Nikitina-Zake, L., Offit, K., Olah, E., Olopade, O. I., Osorio, A., Ott, C. E., Park, S. K., Parsons, M. T., Pedersen, I. S., Peixoto, A., Perez-Segura, P., Peterlongo, P., Pocza, T., Radice, P., Ramser, J., Rantala, J., Rodriguez, G. C., Rønlund, K., Rosenberg, E. H., Rossing, M., Schmutzler, R. K., Shah, P. D., Sharif, S., Sharma, P., Side, L. E., Simard, J., Singer, C. F., Snape, K., Steinemann, D., Stoppa-Lyonnet, D., Sutter, C., Tan, Y. Y., Teixeira, M. R., Teo, S. H., Thomassen, M., Thull, D. L., Tischkowitz, M., Toland, A. E., Trainer, A. H., Tripathi, V., Tung, N., van Engelen, K., van Rensburg, E. J., Vega, A., Viel, A., Walker, L., Weitzel, J. N., Wevers, M. R., Chenevix-Trench, G., Spurdle, A. B., Antoniou, A. C., Walker, L. C., GEMO Study Collaborators, EMBRACE Collaborators, SWE-BRCA Investigators, kConFab Investigators & HEBON Investigators, 6 Oct 2022, In: Communications Biology. 5, 1, 15 p., 1061.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    1 Citation (Scopus)

  • Familial aspects of mammographic density measures associated with breast cancer risk

    Nguyen, T. L., Li, S., Dowty, J. G., Dite, G. S., Ye, Z., Nguyen-Dumont, T., Trinh, H. N., Evans, C. F., Tan, M., Sung, J., Jenkins, M. A., Giles, G. G., Southey, M. C. & Hopper, J. L., 2 Mar 2022, In: Cancers. 14, 6, 10 p., 1483.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    File
    1 Citation (Scopus)

  • First international workshop of the ATM and cancer risk group (4-5 December 2019)

    Lesueur, F., Easton, D. F., Renault, A. L., Tavtigian, S. V., Bernstein, J. L., Kote-Jarai, Z., Eeles, R. A., Plaseska-Karanfia, D., Feliubadaló, L., on behalf of Spanish ATM working group, Arun, B., Herold, N., Versmold, B., Schmutzler, R. K., on behalf of GC-HBOC, Nguyen-Dumont, T., Southey, M. C., Dorling, L., Dunning, A. M., Ghiorzo, P., & 12 othersDalmasso, B. S., Cavaciuti, E., Le Gal, D., Roberts, N. J., Dominguez-Valentin, M., Rookus, M., Taylor, A. M. R., Goldstein, A. M., Goldgar, D. E., on behalf of CARRIERS and Ambry Groups, Stoppa-Lyonnet, D. & Andrieu, N., Apr 2022, In: Familial Cancer. 21, 2, p. 211-227 17 p.

    Research output: Contribution to journal › Review Article › Research › peer-review

    7 Citations (Scopus)
View all 67 research outputs