Projects per year
Personal profile
Biography
Tu Nguyen-Dumont is an Associate Professor of Genomic medicine and Bioinformatics and the Head of Clinical Genomics in the Department of Medicine (Alfred Research Alliance), in the School of Translational Medicine, Monash University. She holds an honorary appointment in the Department of Clinical Pathology, The University of Melbourne and is a Victorian Cancer Agency Mid-career Research Fellow (2022-2026).
She is a molecular geneticist and bioinformatician, with expertise in cancer susceptibility genomics, high-throughput sequencing technologies, sequencing data analysis and genetic variant interpretation.
Tu was awarded a PhD in 2010 from University Claude Bernard, Lyon, France. She completed her PhD training in the Genetic Cancer Susceptibility group at the International Agency for Research on Cancer/World Health Organization (IARC/WHO, France), during which she received a PhD scholarship from Fondation de France and a Special Trainee Award from IARC/WHO. In 2011, she was awarded a Komen Foundation Postdoctoral Fellowship, which allowed her to gain international research experience by moving to Melbourne and training at the Genetic Epidemiology Laboratory, The University of Melbourne.
In 2017, she received a National Breast Cancer Foundation Career Development Fellowship (2017-2021) and was appointed Senior Research Fellow in the Precision Medicine group, School of Clinical Sciences at Monash Health, Monash University. In 2022, she was awarded a Mid-Career Research Fellowship from the Victorian Cancer Agency (2022-2026) and was promoted to Associate Professor in July 2023.
She was appointed Academic Lead of Genomic medicine and Bioinformatics in the School of Translational Medicine, Monash University, in November 2023. The Clinical Genomics group is leading research programs that are generating the knowledge and evidence base to enable the implementation of genomic medicine into mainstream clinical care, with a focus on cancer genomics, public health genomics, translational bioinformatics and pharmacogenomics.
Her research is currently supported by grants from the Victorian Cancer Agency (2022-2026), MRFF (Genomics Health Futures Mission, 2021-2025), NHMRC (Synergy grant, 2022-2026) and Cancer Council Victoria (Grant in Aid, 2023-2025).
Research interests
Genomics, Bioinformatics, Population Health, Cancer, Pharmacogenomics.
High throughput genomic assays, multi-omic analyses.
Precision cell-based immunotherapies.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Molecular biology-Oncogenetics, PhD, Université Claude Bernard Lyon 1 (University Claude Bernard Lyon 1)
Award Date: 15 Dec 2010
External positions
Honorary Research Fellow, University of Melbourne
1 Jul 2017 → 30 Jun 2027
Research area keywords
- genomics
- bioinformatics
Collaborations and top research areas from the last five years
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A data-driven approach to identify and progress new therapeutic targets for paediatric cancers
Sun, C. (Primary Chief Investigator (PCI)), Firestein, R. (Chief Investigator (CI)), Wong, M. (Chief Investigator (CI)), Eisenstat, D. (Associate Investigator (AI)), Powell, D. (Associate Investigator (AI)), Resnick, A. (Associate Investigator (AI)), Ziegler, D. (Associate Investigator (AI)), Koptyra, M. (Associate Investigator (AI)), Nguyen, T. (Associate Investigator (AI)), Danaher, T. (Partner Investigator (PI)), Josefsson, C. (Partner Investigator (PI)) & Goldstein, R. (Partner Investigator (PI))
2/01/23 → 31/12/25
Project: Research
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Leveraging cancer susceptibility genomics for improved precision public health and personalised clinical management
Nguyen, T. (Primary Chief Investigator (PCI)), Rosenbluh, S. (Chief Investigator (CI)), Southey, M. (Chief Investigator (CI)) & Lacaze, P. (Chief Investigator (CI))
Victorian Cancer Agency, Department of Health (DH) (Victoria)
1/04/22 → 30/04/26
Project: Research
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Population genomic screening of young adults to prevent cancer in Australia
Lacaze, P. (Primary Chief Investigator (PCI)), McNeil, J. (Chief Investigator (CI)), Zalcberg, J. (Chief Investigator (CI)), Tiller, J. (Chief Investigator (CI)), Thomas, D. M. (Chief Investigator (CI)), Milne, R. (Chief Investigator (CI)), James, P. A. (Chief Investigator (CI)), Delatycki, M. B. (Chief Investigator (CI)), Young, M. A. (Chief Investigator (CI)), Nowak, K. J. (Chief Investigator (CI)), Nguyen, T. (Chief Investigator (CI)), Southey, M. (Associate Investigator (AI)), Winship, I. M. (Associate Investigator (AI)), Ademi Delaney, Z. (Associate Investigator (AI)), Bruinsma, F. (Associate Investigator (AI)), Riaz, M. (Associate Investigator (AI)), Terrill, B. N. (Associate Investigator (AI)), Kirk, J. A. (Associate Investigator (AI)), Tucker, K. (Associate Investigator (AI)) & Andrews, L. (Associate Investigator (AI))
1/07/21 → 31/05/26
Project: Research
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Personalised T-cell receptor therapy for immunological "cold" cancers
Ho, G.-Y. (Primary Chief Investigator (PCI)), Faridi, P. (Chief Investigator (CI)), Nguyen, T. (Chief Investigator (CI)) & Ooi, J. (Chief Investigator (CI))
Project: Research
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Enabling interpretation of panel tests to advance clinical practice
Nguyen, T. (Primary Chief Investigator (PCI))
National Breast Cancer Foundation
30/06/17 → 30/04/22
Project: Research
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Breast and bowel cancers diagnosed in people ‘too young to have cancer’: A blueprint for research using family and twin studies
Hopper, J. L., Li, S., MacInnis, R. J., Dowty, J. G., Nguyen, T. L., Bui, M., Dite, G. S., Esser, V. F. C., Ye, Z., Makalic, E., Schmidt, D. F., Goudey, B., Alpen, K., Kapuscinski, M., Win, A. K., Dugué, P. A., Milne, R. L., Jayasekara, H., Brooks, J. D. & Malta, S. & 11 others, , Dec 2024, In: Genetic Epidemiology. 48, 8, p. 433-447 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Genetic and environmental causes of variation in an automated breast cancer risk factor based on mammographic textures
Ye, Z., Dite, G. S., Nguyen, T. L., MacInnis, R. J., Schmidt, D. F., Makalic, E., Al-Qershi, O. M., Nguyen-Dumont, T., Goudey, B., Stone, J., Dowty, J. G., Giles, G. G., Southey, M. C., Hopper, J. L. & Li, S., 1 Feb 2024, In: Cancer Epidemiology, Biomarkers and Prevention. 33, 2, p. 306-313 8 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
“Out of the blue”: A qualitative study exploring the experiences of women and next of kin receiving unexpected results from BRA-STRAP research gene panel testing
Morrow, A., Speechly, C., Young, A. L., Tucker, K., Harris, R., Poplawski, N., Andrews, L., Nguyen Dumont, T., Kirk, J., Southey, M. C. & Willis, A., Oct 2024, In: Journal of Genetic Counseling. 33, 5, p. 973-984 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Clonal hematopoiesis and risk of prostate cancer in large samples of European ancestry men
Wang, A., Xu, Y., Yu, Y., Nead, K. T., Kim, T. B., Xu, K., Dadaev, T., Saunders, E., Sheng, X., Wan, P., Pooler, L., Xia, L. Y., Chanock, S., Berndt, S. I., Gapstur, S. M., Stevens, V., Albanes, D., Weinstein, S. J., Gnanapragasam, V. & Giles, G. G. & 19 others, , 13 Jan 2023, In: Human Molecular Genetics. 32, 3, p. 489-495 7 p.Research output: Contribution to journal › Article › Research › peer-review
5 Citations (Scopus) -
Germline Sequencing Analysis to Inform Clinical Gene Panel Testing for Aggressive Prostate Cancer
Darst, B. F., Saunders, E., Dadaev, T., Sheng, X., Wan, P., Pooler, L., Xia, L. Y., Chanock, S., Berndt, S. I., Wang, Y., Patel, A. V., Albanes, D., Weinstein, S. J., Gnanapragasam, V., Huff, C., Couch, F. J., Wolk, A., Giles, G. G., Nguyen-Dumont, T. & Milne, R. L. & 17 others, , 16 Nov 2023, In: JAMA Oncology. 9, 11, p. 1514-1524 11 p.Research output: Contribution to journal › Article › Research › peer-review
18 Citations (Scopus)