Projects per year
Personal profile
Biography
My team studies eukaryotic RNA metabolism in health and disease. Our research is inspired by the fundamental need to understand the human genetic code. Through the combined use of next generation technologies and evolutionary conservation in model organisms, we aim to accelerate the discovery of basic gene-function.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- RNA Biology
- Genomics
- Bioinformatics
- RNA-Seq
- Yeast Cell Biology
- Translation
- Cancer Metastasis
- Developmental Biology
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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MACSYS: ARC Centre of Excellence for the Mathematical Analysis of Cellular Systems
Stumpf, M. (Primary Chief Investigator (PCI)), Flegg, J. (Chief Investigator (CI)), McConville, M. J. (Chief Investigator (CI)), Read, G. (Chief Investigator (CI)), Shim, H. (Chief Investigator (CI)), Coster, A. (Chief Investigator (CI)), Wilkins, M. R. (Chief Investigator (CI)), Zhang, W. (Chief Investigator (CI)), Morris, R. (Chief Investigator (CI)), Beilharz, T. (Chief Investigator (CI)), Lithgow, T. (Chief Investigator (CI)), McDonald, M. (Chief Investigator (CI)), Nguyen, L. (Chief Investigator (CI)), Simpson, M. J. (Chief Investigator (CI)), Drovandi, C. C. (Chief Investigator (CI)), Nayak, R. (Chief Investigator (CI)), Araujo, R. (Chief Investigator (CI)), Wen, J. (Chief Investigator (CI)), Eyras, E. (Chief Investigator (CI)), Stone, E. (Chief Investigator (CI)), Baker, R. E. (Partner Investigator (PI)), Curach, N. (Partner Investigator (PI)), Harrington, H. (Partner Investigator (PI)), Hasenauer, J. (Partner Investigator (PI)), Read, E. L. (Partner Investigator (PI)), Schaerli, Y. (Partner Investigator (PI)), Schmidt, S. (Partner Investigator (PI)), Stelling, J. (Partner Investigator (PI)), Stülke, J. (Partner Investigator (PI)) & Ziemert, N. (Partner Investigator (PI))
8/02/24 → 8/02/30
Project: Research
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Development of novel mRNA products for clinical trials
Pouton, C. (Primary Chief Investigator (PCI)), Beilharz, T. (Chief Investigator (CI)), Carroll, J. (Chief Investigator (CI)), Porter, C. (Chief Investigator (CI)), Al-Wassiti, H. (Chief Investigator (CI)), Davidovich, C. (Chief Investigator (CI)), Johnston, A. (Chief Investigator (CI)) & Trevaskis, N. (Chief Investigator (CI))
10/05/23 → 2/10/28
Project: Research
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The Victorian Pre-clinical mRNA Innovation Incubator (VPMII)
Porter, C. (Primary Chief Investigator (PCI)), Pouton, C. (Chief Investigator (CI)), Carroll, J. (Chief Investigator (CI)), Beilharz, T. (Chief Investigator (CI)), Purcell, D. (Chief Investigator (CI)), Caruso, F. (Chief Investigator (CI)), Trevaskis, N. (Chief Investigator (CI)), Johnston, A. (Chief Investigator (CI)), Davidovich, C. (Chief Investigator (CI)) & Knott, G. (Chief Investigator (CI))
23/06/22 → 22/06/25
Project: Research
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Investigating non-canonical RNA processing in developing spermatids
Beilharz, T. (Primary Chief Investigator (PCI))
1/06/22 → 31/12/25
Project: Research
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Structure-based antigen design as a novel strategy for precision mRNA vaccines
Quast, I. (Primary Chief Investigator (PCI)), Buckle, A. (Chief Investigator (CI)), La Gruta, N. (Chief Investigator (CI)), Hill, D. (Chief Investigator (CI)) & Beilharz, T. (Chief Investigator (CI))
15/05/23 → 15/05/25
Project: Research
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A KLHL40 3' UTR splice-altering variant causes milder NEM8, an under-appreciated disease mechanism
Dofash, L. N. H., Monahan, G. V., Servián-Morilla, E., Rivas, E., Faiz, F., Sullivan, P., Oates, E., Clayton, J., Taylor, R. L., Davis, M. R., Beilharz, T., Laing, N. G., Cabrera-Serrano, M. & Ravenscroft, G., 1 Apr 2023, In: Human Molecular Genetics. 32, 7, p. 1127-1136 10 p.Research output: Contribution to journal › Article › Research › peer-review
8 Citations (Scopus) -
A STAT3 protein complex required for mitochondrial mRNA stability and cancer
Fernando, C. D., Jayasekara, W. S. N., Inampudi, C., Kohonen-Corish, M. R. J., Cooper, W. A., Beilharz, T. H., Josephs, T. M., Garama, D. J. & Gough, D. J., 26 Sept 2023, In: Cell Reports. 42, 9, 14 p., 113033.Research output: Contribution to journal › Article › Research › peer-review
Open Access10 Citations (Scopus) -
Extension of mRNA poly(A) tails and 3′UTRs during neuronal differentiation exhibits variable association with post-transcriptional dynamics
Kiltschewskij, D. J., Harrison, P. F., Fitzsimmons, C., Beilharz, T. H. & Cairns, M. J., 25 Aug 2023, In: Nucleic Acids Research. 51, 15, p. 8181-8198 18 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access8 Citations (Scopus) -
The proteasome regulator Rpn4 controls antifungal drug tolerance by coupling protein homeostasis with metabolic responses to drug stress
Yau, K. P. S., Weerasinghe, H., Olivier, F. A. B., Lo, T. L., Powell, D. R., Koch, B., Beilharz, T. H. & Traven, A., 1 Apr 2023, In: PLoS Pathogens. 19, 4, 26 p., e1011338.Research output: Contribution to journal › Article › Research › peer-review
Open Access8 Citations (Scopus) -
The short-chain fatty acid crotonate reduces invasive growth and immune escape of Candida albicans by regulating hyphal gene expression
McCrory, C., Verma, J., Tucey, T. M., Turner, R. E., Weerasinghe, H., Beilharz, T. & Traven, A., Dec 2023, In: mBio. 14, 6, 22 p., e0260523.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Citations (Scopus)
Prizes
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Press/Media
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Monash Uni stakes its claim for Moderna’s mRNA facility
18/02/22
1 Media contribution
Press/Media: Expert Comment
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Funding makes cracking Covid-19 vaccine code a tougher ask
5/11/21
1 Media contribution
Press/Media: Expert Comment
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Researchers target choke point in RNA revolution
8/09/21
1 Media contribution
Press/Media: Expert Comment
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RNA is the future. So... what can you do with it?
22/08/21
1 Media contribution
Press/Media: Expert Comment