20072018
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Research Output 2007 2018

2018
4 Citations (Scopus)

Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans

Grant, E. J., Josephs, T. M., Loh, L., Clemens, E. B., Sant, S., Bharadwaj, M., Chen, W., Rossjohn, J., Gras, S. & Kedzierska, K., 21 Dec 2018, In : Nature Communications. 9, 1, 16 p., 5427.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
3 Citations (Scopus)

Identification of global and ligand-specific calcium sensing receptor activation mechanisms S

Keller, A., Kufareva, I., Josephs, T. M., Diao, J., Mai, V. T-V., Conigrave, A. D., Christopoulos, A., Gregory, K. J. & Leach, K., 1 Jun 2018, In : Molecular Pharmacology. 93, 6, p. 619-630 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2017
11 Citations (Scopus)

A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene

Van Braeckel-Budimir, N., Gras, S., Ladell, K., Josephs, T. M., Pewe, L., Urban, S. L., Miners, K. L., Farenc, C., Price, D. A., Rossjohn, J. & Harty, J. T., 21 Nov 2017, In : Immunity. 47, 5, p. 835-847 14 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Molecular challenges imposed by MHC-I restricted long epitopes on T cell immunity

Josephs, T. M., Grant, E. J. & Gras, S., 28 Aug 2017, In : Biological Chemistry. 398, 9, p. 1027-1036 10 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

2016
10 Citations (Scopus)

HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection

Du, V. Y., Bansal, A., Carlson, J., Salazar-Gonzalez, J. F., Salazar, M. G., Ladell, K., Gras, S., Josephs, T. M., Heath, S. L., Price, D. A., Rossjohn, J., Hunter, E. & Goepfert, P. A., 15 Apr 2016, In : Journal of Immunology. 196, 8, p. 3276-3286 11 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Lack of heterologous cross-reactivity toward HLA-A02: 01 restricted viral epitopes is underpinned by distinct αβT cell receptor signatures

Grant, E. J., Josephs, T. M., Valkenburg, S. A., Wooldridge, L., Hellard, M., Rossjohn, J., Bharadwaj, M., Kedzierska, K. & Gras, S., 18 Nov 2016, In : Journal of Biological Chemistry. 291, 47, p. 24335-24351 17 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)

Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses

Valkenburg, S. A., Josephs, T. M., Clemens, E. B., Grant, E. J., Nguyen, T. H. O., Wang, G. C., Price, D. A., Miller, A., Tong, S. Y. C., Thomas, P. G., Doherty, P. C., Rossjohn, J., Gras, S. & Kedzierska, K., 19 Apr 2016, In : Proceedings of the National Academy of Sciences. 113, 16, p. 4440-4445 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
28 Citations (Scopus)

Reversed T cell receptor docking on a major histocompatibility class I complex limits involvement in the immune response

Gras, S., Chadderton, J., Del Campo, C. M., Farenc, C., Wiede, F., Josephs, T. M., Sng, X. Y. X., Mirams, M., Watson, K. A., Tiganis, T., Quinn, K. M., Rossjohn, J. & La Gruta, N. L., 18 Oct 2016, In : Immunity. 45, 4, p. 749-760 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2015
4 Citations (Scopus)

Interspecies variation in the functional consequences of mutation of cytochrome c

Josephs, T. M., Hibbs, M. E., Ong, L., Morison, I. M. & Ledgerwood, E. C., 2015, In : PLoS ONE. 10, 6, 13 p., e0130292.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2014
27 Citations (Scopus)

Enhancing the peroxidase activity of cytochrome c by mutation of residue 41: implications for the peroxidase mechanism and cytochrome c release

Josephs, T. M., Morison, I., Day, C. L., Wilbanks, S. & Ledgerwood, E. C., 2014, In : Biochemical Journal. 458, 2, p. 259 - 265 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2013
27 Citations (Scopus)

Conformational change and human cytochrome c function: Mutation of residue 41 modulates caspase activation and destabilizes Met-80 coordination

Josephs, T. M., Liptak, M. D., Hughes, G., Brazinova, A., Smith, R. M., Wilbanks, S. M., Bren, K. L. & Ledgerwood, E. C., Mar 2013, In : Journal of Biological Inorganic Chemistry. 18, 3, p. 289-297 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2007
21 Citations (Scopus)

Fasting-induced adipose factor identified as a key adipokine that is up-regulated in white adipose tissue during pregnancy and lactation in the rat

Josephs, T., Waugh, H., Kokay, I., Grattan, D. & Thompson, M., 1 Aug 2007, In : Journal of Endocrinology. 194, 2, p. 305-312 8 p.

Research output: Contribution to journalArticleResearchpeer-review