Dr Josephs leads G protein coupled receptor (GPCR) structural-dynamics research as an independent investigator in the collaborative Endocrinology and Neuropharmacology Laboratory at the Monash Institute of Pharmaceutical Sciences (MIPS). Dr Josephs comprehensive interdisciplinary PhD and post-doctoral training has been undertaken at the best national (Monash University) and international laboratories, including Duke University, the University of North Carolina (USA), and Otago University (NZ). She has built extensive biophysical, structural biology and pharmacological technical expertise, and applied these to unravel atomic and molecular insights into proteins that are critical for human health and fundamental to cellular processes. Dr Josephs research projects have spanned programmed cell death, immunology and drug discovery biology; however, her consistent research themes are to elucidate and validate molecular insights into protein structure and dynamics. In the past 2 years Dr Josephs has built an independent research program at MIPS around her core competencies in protein structural dynamics and function applied to understanding GPCR macromolecular interactions critical for cellular signal transduction.