Projects per year
Personal profile
Biography
I am a post-doctoral fellow working in the Neuroimmunology, Neuroinflammation and Neurooncology Laboratory.My research involves examining the role of neuroinflammation in epilepsy and seizures. I am also analysing electroencephalogram (EEG) signals from patients with autoimmune encephalitis and correlating them with patient symptoms, brain scans and outcomes to find unique patterns that may help clinicians more rapidly predict disease subtype and severity and thereby optimise patient management. I have completed the highest level of training (level 3) in EEG interpretation from ANZAN (Australia and New Zealand Association of Neurologists) which allows me to establish an EEG laboratory at a hospital or teaching institution.
I received my PhD in 2024 exploring the role of various immune and inflammation related biomarkers in human drug resistant epilepsy and status epilepticus and their implications for diagnosis, prognosis and future treatment trials.
My training as a clinician neurologist specialising in epilepsy as well as neuroimmunology, and my laboratory skills in neuroscience, allows me a deeper appreciation of bench to bedside translational clinical research. My experience treating patients with seizures, epilepsy and autoimmune
encephalitis and the diagnostic and prognostic uncertainties frequently encountered, has given me a passion to engage in further research in this field.
I work as part of the Australian Autoimmune Encephalitis Consortium – an Australia first collaborative translational research network focusing on autoimmune encephalitides which has, to date, enrolled over 350 patients with AE from 14 sites across the country.
Clinical activities
I am a neurologist at Alfred Health practicing in the subspeciality fields of epilepsy and neuroimmunology following the completion of dual clinical fellowships in both epilepsy and neuroimmunology.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Pharmacy, BPharm
Medicine/Surgery, MBBS, University of Melbourne
Research area keywords
- epilepsy
- neuroimmunology
Collaborations and top research areas from the last five years
Projects
- 1 Active
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Electroencephalogram (EEG) in autoimmune encephalitis diagnosis and prognosis.
Tan, T., Monif, M., Wesselingh, R., Seery, N., Kwan, P. & O'Brien, T.
1/01/25 → 1/01/26
Project: Research
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Inflammation, ictogenesis, and epileptogenesis: An exploration through human disease
Tan, T. H. L., Perucca, P., O’Brien, T. J., Kwan, P. & Monif, M., Feb 2021, In: Epilepsia. 62, 2, p. 303-324 22 p.Research output: Contribution to journal › Article › Research › peer-review
61 Citations (Scopus) -
Development and validation of a peripheral cell ratio and lactate score for differentiating status epilepticus from prolonged psychogenic nonepileptic seizures
Tan, T. H. L., Sanfilippo, P., Colman, B., Perucca, P., Kwan, P., O'Brien, T. J. & Monif, M., Dec 2023, In: Epilepsia Open. 8, 4, p. 1460-1473 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Citations (Scopus) -
Human In Vitro Models of Epilepsy Using Embryonic and Induced Pluripotent Stem Cells
Javaid, M. S., Tan, T., Dvir, N., Anderson, A., J. O’Brien, T., Kwan, P. & Antonic-Baker, A., Dec 2022, In: Cells. 11, 24, 16 p., 3957.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access9 Citations (Scopus) -
Real-world efficacy, roll-out and uptake of intramuscular tixagevimab/ cilgavimab as COVID-19 pre-exposure prophylaxis in people with multiple sclerosis and neuroimmunological conditions during the COVID-19 pandemic
Rath, L., Yeh, W. Z., Roldan, A., Wesselingh, R., Zhong, M., Tan, T., Seery, N., Bridge, F., Foong, Y. C., Skibina, O., Nesbitt, C., Butzkueven, H., Monif, M. & van der Walt, A., 30 Apr 2024, In: BMJ Neurology Open. 6, 1, 9 p., e000667.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Neutropaenia complications from Ocrelizumab and Rituximab treatment
Pang, V., Seery, N., Wesselingh, R., Yeh, W., Zhong, M., Tan, T., Dwyer, C., Nesbitt, C., Rath, L., Perera, D., Bridge, F., Skibina, O., Bosco, J. J., Jokubaitis, V., Marriott, M., Butkueven, H., Van Der Walt, A., Massey, J., Sutton, I. & Monif, M., Jan 2024, In: Multiple Sclerosis and Related Disorders. 81, 6 p., 105147.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Citations (Scopus)