Tracey Brown

Adj Assoc Prof

19922015
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Research Output 1992 2015

2015
18 Citations (Scopus)

Intracellular survival of leishmania major depends on uptake and degradation of extracellular matrix glycosaminoglycans by macrophages

Naderer, T., Heng, J., Saunders, E. C., Kloehn, J., Rupasinghe, T. W. T., Brown, T. J. & McConville, M. J., 2015, In : PLoS Pathogens. 11, 9, 20 p., e1005136.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2014
4 Citations (Scopus)

The H.G. Smith award article: fluorescent analogues of NAMI-A: synthesis, characterisation, fluorescent properties, and preliminary biological studies in human lung cancer cells

Antony, S., Morris, J. C., Bell, T. D. M., Brown, T. J., Spiccia, L. & Harris, H. H., 2014, In : Australian Journal of Chemistry. 67, 12, p. 1711 - 1717 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2013
20 Citations (Scopus)

Next-generation sequence analysis of cancer xenograft models

Rossello, F. J., Tothill, R., Britt, K. L., Marini, K. D., Falzon, J., Thomas, D. M., Peacock, C. D., Marchionni, L., Li, J., Bennett, S., Tantoso, E., Brown, T. J., Chan, P., Martelotto, L. G. & Watkins, D. N., 2013, In : PLoS ONE. 8, 9, 12 p., e7443.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
47 Citations (Scopus)

The prognostic significance of aldehyde dehydrogenase 1A1 (ALDH1A1) and CD133 expression in early stage non-small cell lung cancer

Alamgeer, M., Ganju, V., Szczepny, A., Russell, P. A., Prodanovic, Z., Kumar, B., Wainer, Z., Brown, T. J., Schneider-Kolsky, M., Conron, M., Wright, G. & Watkins, D. N., 2013, In : Thorax. 68, 12, p. 1095 - 1104 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
13 Citations (Scopus)

X-ray fluorescence imaging of single human cancer cells reveals that the N-heterocyclic ligands of iodinated analogues of ruthenium anticancer drugs remain coordinated after cellular uptake

Antony, S., Aitken, J. B., Vogt, S., Lai, B., Brown, T. J., Spiccia, L. & Harris, H. H., 2013, In : Journal of Biological Inorganic Chemistry. 18, 7, p. 845 - 853 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2011
158 Citations (Scopus)

A crucial requirement for Hedgehog signaling in small cell lung cancer

Park, K-S., Martelotto, L., Peifer, M., Sos, M., Karnezis, A., Mahjoub, M., Bernard, K., Conklin, J., Szczepny, A., Yuan, J., Guo, R., Ospina, B., Falzon, J., Bennett, S., Brown, T., Markovic, A., Devereux, W., Ocasio, C., Chen, J., Stearns, T. & 6 others, Thomas, R., Dorsch, M., Buonamici, S., Watkins, D., Peacock, C. & Sage, J., 2011, In : Nature Medicine. 17, 11, p. 1504 - 1508 5 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Hyaluronan-Irinotecan improves progression-free survival in 5-fluorouracil refractory patients with metastatic colorectal cancer: a randomized phase II trial

Gibbs, P., Clingan, P., Ganju, V., Strickland, A. H., Wong, S. S., Tebbutt, N. C., Underhill, C. R., Fox, R. M., Clavant, S. P., Leung, J. Y., Pho, M. H. & Brown, T. J., 2011, In : Cancer Chemotherapy and Pharmacology. 67, p. 153 - 163 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2010
16 Citations (Scopus)

ABC transporters do not contribute to extracellular translocation of hyaluronan in human breast cancer in vitro

Thomas, N. K. & Brown, T. J., 2010, In : Experimental Cell Research. 316, 7, p. 1241 - 1253 13 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Hyaluronan: Is it a biomarker for adipose development within bovine muscle?

Allingham, P., Greenwood, P. L., Brown, T. J. & Harper, G. S., 2010, In : Animal Production Science. 50, 2, p. 88 - 97 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2009
21 Citations (Scopus)

A pilot human evaluation of a formulation of irinotecan and hyaluronic acid in 5-fluorouracil-refractory metastatic colorectal cancer patients

Gibbs, P., Brown, T. J., Ng, R., Jennens, R., Cinc, E., Pho, M. H., Michael, M. & Fox, R. M., 2009, In : Chemotherapy. 55, p. 49 - 59 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Role of Hyaluronan Metabolism in the Initiation, Invasion, and Metastasis of Breast Cancer

Brown, T. J. & Thomas, N. K., 2009, Hyaluronan in Cancer Biology. Elsevier, p. 341-360 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

2008
31 Citations (Scopus)

The development of hyaluronan as a drug transporter and excipient for chemotherapeutic drugs

Brown, T. J., 2008, In : Current Pharmaceutical Biotechnology. 9, 4, p. 253 - 260 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2007
97 Citations (Scopus)

Silencing of hyaluronan synthase 2 suppresses the malignant phenotype of invasive breast cancer cells

Li, Y., Li, L., Brown, T. J. & Heldin, P., 2007, In : International Journal of Cancer. 120, 12, p. 2557 - 2567 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2006
17 Citations (Scopus)

Gene expression, synthesis and degradation of hyaluronan during differentiation of 3T3-L1 adipocytes

Allingham, P., Brownlee, G. R., Harper, G., Pho, M. H., Nilsson, S. K. & Brown, T. J., 2006, In : Archives of Biochemistry and Biophysics. 452, 1, p. 83 - 91 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2005

Antisense-mediated suppression of hyaluronan synthase 2 inhibits the initiation and progression of breast cancer

Udabage, L., Brownlee, G. R., Nilsson, S. K., Heldin, P. & Brown, T. J., 2005, Hyaluronan Structure, Metabolism, Biological Activities, Therapeutic Applications. Balazs, E. A. & Hascall, V. C. (eds.). 1st (2 Volume Set) ed. Edgewater NJ USA: Matrix Biology Institute, p. 339 - 347 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

102 Citations (Scopus)

Antisense-mediated suppression of hyaluronan synthase 2 inhibits the tumorigenesis and progression of breast cancer

Udabage, L., Brownlee, G. R., Waltham, M., Blick, T., Walker, E. C., Heldin, P., Nilsson, S. K., Thompson, E. W. & Brown, T. J., 2005, In : Cancer Research. 65, 14, p. 6139 - 6150 12 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Phase I and pharmacokinetic evaluation of intravenous hyaluronic acid in combination with doxorubicin or 5-fluorouracil

Rosenthal, M. A., Gibbs, P., Brown, T. J., Wong, S., Uren, S., Ellis, A. G., Li, L., Heldin, P. & Fox, R. M., 2005, In : Chemotherapy. 51, 2-3, p. 132 - 141 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis of hyaluronan during growth and differentiation of 3T3-L1 adipocytes

Allingham, P., Brownlee, G. R., Harper, G. & Brown, T. J., 2005, Hyaluronan Structure, Metabolism, Biological Activities, Therapeutic Applications. Balazs, E. A. & Hascall, V. C. (eds.). 1st ed. New Jersey USA: Matrix Biology Institute, p. 133 - 142 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

The development of hyaluronic acid as a targeted transport vehicle for chemotherapeutic drugs

Brown, T. J., Falzon, J., Pho, M. H., Hatherell, E., Vaghela, K. V., Wilson, J. C., Fox, R., Gibbs, P., Rosenthal, M. A., Fraser, J. R. E. & Brownlee, G. R., 2005, Hyaluronan Structure, Metabolism, Biological Activities, Therapeutic Applications. Balazs, E. A. & Hascall, V. C. (eds.). 1st ed. New Jersey USA: Matrix Biology Institute, p. 421 - 433 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

152 Citations (Scopus)

The over-expression of HAS2, Hyal-2 and CD44 is implicated in the invasiveness of breast cancer

Udabage, L., Brownlee, G. R., Nilsson, S. K. & Brown, T. J., 2005, In : Experimental Cell Research. 310, 1, p. 205 - 217 13 p.

Research output: Contribution to journalArticleResearchpeer-review

The role of hyaluronic acid in normal and perturbed hemopoietic stem cell biology

Shaw, S., Haylock, D. N., Lock, R. B., Bendall, L., Simmons, P. J., Johnston, H. M., Fletcher, K., Webb, R., Brown, T. J., Liem, N. L. & Nilsson, S. K., 2005, Hyaluronan Structure, Metabolism, Biological Activities, Therapeutic Applications. Balazs, E. A. & Hascall, V. C. (eds.). 1st ed. New Jersey USA: Matrix Biology Institute, p. 293 - 299 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

2004
18 Citations (Scopus)

Inhibition of hyaluronan degradation by dextran sulphate facilitates charecterisation of hyularonan synthesis: an in vitro and in vivo study

Udabage, L., Brownlee, G. R., Stern, R. & Brown, T. J., 2004, In : Glycoconjugate Journal. 20, 7-8, p. 461 - 471 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2003
112 Citations (Scopus)

Hyaluronan is synthesized by primitive hemopoietic cells, participates in their lodgment at the endosteum following transplantation, and is involved in the regulation of their proliferation and differentiation in vitro

Nilsson, S. K., Haylock, D. N., Johnston, H. M., Occhiodoro, T., Brown, T. J. & Simmons, P. J., 1 Feb 2003, In : Blood. 101, 3, p. 856-862 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2001
29 Citations (Scopus)

The histochemical structure of the deep fascia and its structural response to surgery

McCombe, D., Brown, T. J., Slavin, J. & Morrison, W., 2001, In : Journal of Hand Surgery. 26B, 2, p. 1 - 9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2000
24 Citations (Scopus)

A new disorder of hyaluronan metabolism associated with generalized folding and thickening of the skin

Ramsden, C. A., Bankier, A., Brown, T. J., Cowen, P. S. J., Frost, G. I., McCallum, D. D., Studdert, V. P. & Fraser, J. R. E., 2000, In : Journal of Pediatrics. p. 62 - 68 7 p.

Research output: Contribution to journalArticleResearchpeer-review

169 Citations (Scopus)

Assessment of long-term outcomes of community-acquired hepatitis C infection in a cohort with sera stored from 1971 to 1975

Rodger, A. J., Roberts, S., Lanigan, A., Bowden, D. S., Brown, T. J. & Crofts, N., 2000, In : Hepatology. p. 582 - 587 6 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Biosynthesis of glycosaminoglycans and proteoglycans by the lymph node

Brown, T. J., Kimpton, W. G. & Fraser, J. R. E., 2000, In : Glycoconjugate Journal. 17, 11, p. 795 - 805 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1999

Adsorption of hyaluronan applied to the surface of intact skin

Brown, T. J., Alcorn, D. & Fraser, J. R. E., 1999, In : Journal of Investigative Dermatology. p. 740 - 746 7 p.

Research output: Contribution to journalArticleResearchpeer-review

1998

Catabolism of hyaluronan

Fraser, J. R. E., Brown, T. J. & Laurent, T. C., 1998, The Chemistry, Biology and Medical Applications of Hyaluronan and its Derivatives. London UK: Portland Press Ltd., p. 85 - 92 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

1992
64 Citations (Scopus)

Hemodynamic and liver function predictors of serum hyaluronan in alcoholic liver disease

Gibson, P. R., Fraser, J. R. E., Brown, T. J., Finch, C. F., Jones, P. A., Colman, J. C. & Dudley, F. J., Jun 1992, In : Hepatology. 15, 6, p. 1054-1059 6 p.

Research output: Contribution to journalArticleResearchpeer-review