20042017

Research output per year

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Research Output

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Review Article
2017

Pharmacological histone deacetylation distinguishes transcriptional regulators

Rafehi, H., Karagiannis, T. C. & El-Osta, A., 1 May 2017, In : Current Topics in Medicinal Chemistry. 17, 14, p. 1611 - 1622 12 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

3 Citations (Scopus)
2015

Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K

Courtnay, R., Ngo, D. C., Malik, N., Ververis, K., Tortorella, S. M. & Karagiannis, T. C., Apr 2015, In : Molecular Biology Reports. 42, 4, p. 841-851 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

162 Citations (Scopus)

Introduction to the molecular basis of cancer metabolism and the Warburg effect

Ngo, D. C., Ververis, K., Tortorella, S. M. & Karagiannis, T. C., Apr 2015, In : Molecular Biology Reports. 42, 4, p. 819-823 5 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

36 Citations (Scopus)

Lactate as an insidious metabolite due to the Warburg effect

Luc, R., Tortorella, S. M., Ververis, K. & Karagiannis, T. C., Apr 2015, In : Molecular Biology Reports. 42, 4, p. 835-840 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

11 Citations (Scopus)

The early life origin theory in the development of cardiovascular disease and type 2 diabetes

Lindblom, R., Ververis, K., Tortorella, S. M. & Karagiannis, T. C., Apr 2015, In : Molecular Biology Reports. 42, 4, p. 791-797 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

15 Citations (Scopus)

The Implication of Cancer Progenitor Cells and the Role of Epigenetics in the Development of Novel Therapeutic Strategies for Chronic Myeloid Leukemia

Tortorella, S. M., Hung, A. & Karagiannis, T. C., 1 Jun 2015, In : Antioxidants and Redox Signaling. 22, 16, p. 1425-1462 38 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

5 Citations (Scopus)

The Warburg effect: molecular aspects and therapeutic possibilities

Ngo, H., Tortorella, S. M., Ververis, K. & Karagiannis, T. C., Apr 2015, In : Molecular Biology Reports. 42, 4, p. 825-834 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

48 Citations (Scopus)
2014

The significance of transferrin receptors in oncology: The development of functional nano-based drug delivery systems

Tortorella, S. & Karagiannis, T. C., 2014, In : Current Drug Delivery. 11, 4, p. 427-443 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

31 Citations (Scopus)

The timeless influence of Hippocratic ideas on diet, salicylates and personalized medicine

Karagiannis, T. C., 2014, In : Hellenic Journal of Nuclear Medicine. 17, 1, p. 2-6 5 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

7 Citations (Scopus)

Transferrin receptor-mediated endocytosis: A useful target for cancer therapy

Tortorella, S. & Karagiannis, T. C., Apr 2014, In : Journal of Membrane Biology. 247, 4, p. 291-307 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

151 Citations (Scopus)
2013

Histone deacetylase inhibitors (HDACIS): Multitargeted anticancer agents

Ververis, K., Hiong, A., Karagiannis, T. C. & Licciardi, P. V., 23 Feb 2013, In : Biologics: Targets and Therapy. 7, 1, p. 47-60 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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210 Citations (Scopus)

The potential role of HDAC inhibitors in de-silencing latent HIV virus

Ververis, K. & Karagiannis, T. C., 2013, In : Drugs of the Future. 38, 8, p. 575-583 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2012

Controversies surrounding the clinical potential of cinnamon for the management of diabetes

Rafehi, H., Ververis, K. & Karagiannis, T. C., Jun 2012, In : Diabetes, Obesity and Metabolism. 14, 6, p. 493-499 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

43 Citations (Scopus)

Factors influencing epigenetic mechanisms and related diseases

Karagiannis, T. C. & Maulik, N., 15 Jul 2012, In : Antioxidants and Redox Signaling. 17, 2, p. 192-194 3 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

7 Citations (Scopus)

Mechanisms of action of phenolic compounds in olive

Rafehi, H., Ververis, K. & Karagiannis, T. C., Jun 2012, In : Journal of Dietary Supplements. 9, 2, p. 96-109 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

29 Citations (Scopus)

Safety and efficacy of Pralatrexate in the management of relapsed or refractory peripheral T-cell lymphoma

Rodd, A. L., Ververis, K. & Karagiannis, T. C., 2012, In : Clinical Medicine Insights: Oncology. 6, p. 305-314 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)
2011

Chromatin modifying agents - The cutting edge of anticancer therapy

Kwa, F. A. A., Balcerczyk, A., Licciardi, P., El-Osta, A. & Karagiannis, T. C., Jul 2011, In : Drug Discovery Today. 16, 13-14, p. 543-547 5 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

25 Citations (Scopus)

Double-strand breaks and the concept of short- and long-term epigenetic memory

Orlowski, C., Mah, L-J., Vasireddy, R. S., El-Osta, A. & Karagiannis, T. C., Apr 2011, In : Chromosoma. 120, 2, p. 129-149 21 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

15 Citations (Scopus)

Evaluation of the efficacy of radiation-modifying compounds using γH2AX as a molecular marker of DNA double-strand breaks

Mah, L-J., Orlowski, C., Ververis, K., Vasireddy, R. S., El-Osta, A. & Karagiannis, T. C., 25 Jan 2011, In : Genome Integrity. 2, 11 p., 3.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File
19 Citations (Scopus)

Potential non-oncological applications of histone deacetylase inhibitors

Ververis, K. & Karagiannis, T. C., 2011, In : American Journal of Translational Research. 3, 5, p. 454-467 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File
22 Citations (Scopus)
12 Citations (Scopus)
2010

γh2AX: A sensitive molecular marker of DNA damage and repair

Mah, L. J., El-Osta, A. & Karagiannis, T. C., Apr 2010, In : Leukemia. 24, 4, p. 679-686 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

449 Citations (Scopus)

γH2AX as a molecular marker of aging and disease

Mah, L. J., El-Osta, A. & Karagiannis, T. C., 2010, In : Epigenetics. 5, 2, p. 129-136 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

68 Citations (Scopus)
2007

Chromatin modifications and DNA double-strand breaks: The current state of play

Karagiannis, T. C. & El-Osta, A., 1 Jan 2007, In : Leukemia. 21, 2, p. 195-200 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

32 Citations (Scopus)

Will broad-spectrum histone deacetylase inhibitors be superseded by more specific compounds?

Karagiannis, T. C. & El-Osta, A., 1 Jan 2007, In : Leukemia. 21, 1, p. 61-65 5 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

89 Citations (Scopus)
2006

Clinical potential of histone deacetylase inhibitors as stand alone therapeutics and in combination with other chemotherapeutics or radiotherapy for cancer

Karagiannis, T. C. & El-Osta, A., 1 Jan 2006, In : Epigenetics. 1, 3, p. 121-126 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

31 Citations (Scopus)

Modulation of cellular radiation responses by histone deacetylase inhibitors

Karagiannis, T. C. & El-Osta, A., 29 Jun 2006, In : Oncogene. 25, 28, p. 3885-3893 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

70 Citations (Scopus)

The paradox of histone deacetylase inhibitor-mediated modulation of cellular responses to radiation

Karagiannis, T. C. & El-Osta, A., 1 Feb 2006, In : Cell Cycle. 5, 3, p. 288-295 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

31 Citations (Scopus)
2005

RNA interference and potential therapeutic applications of short interfering RNAs

Karagiannis, T. C. & El-Osta, A., 1 Oct 2005, In : Cancer Gene Therapy. 12, 10, p. 787-795 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

108 Citations (Scopus)
2004

Double-strand breaks: Signaling pathways and repair mechanisms

Karagiannis, T. C. & El-Osta, A., 1 Sep 2004, In : Cellular and Molecular Life Sciences. 61, 17, p. 2137-2147 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

65 Citations (Scopus)

Epigenetic changes activate widespread signals in response to double-strand breaks

Karagiannis, T. C. & El-Osta, A., 1 Jan 2004, In : Cancer Biology and Therapy. 3, 7, p. 617-623 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

7 Citations (Scopus)

siRNAs: Mechanism of RNA interference, in vivo and potential clinical applications

Karagiannis, T. C. & El-Osta, A., 1 Jan 2004, In : Cancer Biology and Therapy. 3, 11

Research output: Contribution to journalReview ArticleResearchpeer-review

26 Citations (Scopus)