Research Output per year
Research Output
2017
Pharmacological histone deacetylation distinguishes transcriptional regulators
Rafehi, H., Karagiannis, T. C. & El-Osta, A., 1 May 2017, In : Current Topics in Medicinal Chemistry. 17, 14, p. 1611 - 1622 12 p.Research output: Contribution to journal › Review Article › Research › peer-review
3
Citations
(Scopus)
2015
Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K
Courtnay, R., Ngo, D. C., Malik, N., Ververis, K., Tortorella, S. M. & Karagiannis, T. C., Apr 2015, In : Molecular Biology Reports. 42, 4, p. 841-851 11 p.Research output: Contribution to journal › Review Article › Research › peer-review
162
Citations
(Scopus)
Introduction to the molecular basis of cancer metabolism and the Warburg effect
Ngo, D. C., Ververis, K., Tortorella, S. M. & Karagiannis, T. C., Apr 2015, In : Molecular Biology Reports. 42, 4, p. 819-823 5 p.Research output: Contribution to journal › Review Article › Research › peer-review
36
Citations
(Scopus)
Lactate as an insidious metabolite due to the Warburg effect
Luc, R., Tortorella, S. M., Ververis, K. & Karagiannis, T. C., Apr 2015, In : Molecular Biology Reports. 42, 4, p. 835-840 6 p.Research output: Contribution to journal › Review Article › Research › peer-review
11
Citations
(Scopus)
The early life origin theory in the development of cardiovascular disease and type 2 diabetes
Lindblom, R., Ververis, K., Tortorella, S. M. & Karagiannis, T. C., Apr 2015, In : Molecular Biology Reports. 42, 4, p. 791-797 7 p.Research output: Contribution to journal › Review Article › Research › peer-review
15
Citations
(Scopus)
The Implication of Cancer Progenitor Cells and the Role of Epigenetics in the Development of Novel Therapeutic Strategies for Chronic Myeloid Leukemia
Tortorella, S. M., Hung, A. & Karagiannis, T. C., 1 Jun 2015, In : Antioxidants and Redox Signaling. 22, 16, p. 1425-1462 38 p.Research output: Contribution to journal › Review Article › Research › peer-review
5
Citations
(Scopus)
The Warburg effect: molecular aspects and therapeutic possibilities
Ngo, H., Tortorella, S. M., Ververis, K. & Karagiannis, T. C., Apr 2015, In : Molecular Biology Reports. 42, 4, p. 825-834 10 p.Research output: Contribution to journal › Review Article › Research › peer-review
48
Citations
(Scopus)
2014
The significance of transferrin receptors in oncology: The development of functional nano-based drug delivery systems
Tortorella, S. & Karagiannis, T. C., 2014, In : Current Drug Delivery. 11, 4, p. 427-443 17 p.Research output: Contribution to journal › Review Article › Research › peer-review
31
Citations
(Scopus)
The timeless influence of Hippocratic ideas on diet, salicylates and personalized medicine
Karagiannis, T. C., 2014, In : Hellenic Journal of Nuclear Medicine. 17, 1, p. 2-6 5 p.Research output: Contribution to journal › Review Article › Other › peer-review
7
Citations
(Scopus)
Transferrin receptor-mediated endocytosis: A useful target for cancer therapy
Tortorella, S. & Karagiannis, T. C., Apr 2014, In : Journal of Membrane Biology. 247, 4, p. 291-307 17 p.Research output: Contribution to journal › Review Article › Research › peer-review
151
Citations
(Scopus)
2013
Histone deacetylase inhibitors (HDACIS): Multitargeted anticancer agents
Ververis, K., Hiong, A., Karagiannis, T. C. & Licciardi, P. V., 23 Feb 2013, In : Biologics: Targets and Therapy. 7, 1, p. 47-60 14 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access
File
210
Citations
(Scopus)
The potential role of HDAC inhibitors in de-silencing latent HIV virus
Ververis, K. & Karagiannis, T. C., 2013, In : Drugs of the Future. 38, 8, p. 575-583 9 p.Research output: Contribution to journal › Review Article › Research › peer-review
2012
Controversies surrounding the clinical potential of cinnamon for the management of diabetes
Rafehi, H., Ververis, K. & Karagiannis, T. C., Jun 2012, In : Diabetes, Obesity and Metabolism. 14, 6, p. 493-499 7 p.Research output: Contribution to journal › Review Article › Research › peer-review
43
Citations
(Scopus)
Factors influencing epigenetic mechanisms and related diseases
Karagiannis, T. C. & Maulik, N., 15 Jul 2012, In : Antioxidants and Redox Signaling. 17, 2, p. 192-194 3 p.Research output: Contribution to journal › Review Article › Other › peer-review
7
Citations
(Scopus)
Mechanisms of action of phenolic compounds in olive
Rafehi, H., Ververis, K. & Karagiannis, T. C., Jun 2012, In : Journal of Dietary Supplements. 9, 2, p. 96-109 14 p.Research output: Contribution to journal › Review Article › Research › peer-review
29
Citations
(Scopus)
Safety and efficacy of Pralatrexate in the management of relapsed or refractory peripheral T-cell lymphoma
Rodd, A. L., Ververis, K. & Karagiannis, T. C., 2012, In : Clinical Medicine Insights: Oncology. 6, p. 305-314 10 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access
File
5
Citations
(Scopus)
2011
Chromatin modifying agents - The cutting edge of anticancer therapy
Kwa, F. A. A., Balcerczyk, A., Licciardi, P., El-Osta, A. & Karagiannis, T. C., Jul 2011, In : Drug Discovery Today. 16, 13-14, p. 543-547 5 p.Research output: Contribution to journal › Review Article › Research › peer-review
25
Citations
(Scopus)
Double-strand breaks and the concept of short- and long-term epigenetic memory
Orlowski, C., Mah, L-J., Vasireddy, R. S., El-Osta, A. & Karagiannis, T. C., Apr 2011, In : Chromosoma. 120, 2, p. 129-149 21 p.Research output: Contribution to journal › Review Article › Research › peer-review
15
Citations
(Scopus)
Evaluation of the efficacy of radiation-modifying compounds using γH2AX as a molecular marker of DNA double-strand breaks
Mah, L-J., Orlowski, C., Ververis, K., Vasireddy, R. S., El-Osta, A. & Karagiannis, T. C., 25 Jan 2011, In : Genome Integrity. 2, 11 p., 3.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access
File
19
Citations
(Scopus)
Potential non-oncological applications of histone deacetylase inhibitors
Ververis, K. & Karagiannis, T. C., 2011, In : American Journal of Translational Research. 3, 5, p. 454-467 14 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access
File
22
Citations
(Scopus)
Utility of γH2AX as a molecular marker of DNA double-strand breaks in nuclear medicine: Applications to radionuclide therapy employing auger electron-emitting isotopes
Mah, L-J., Orlowski, C., Ververis, K., El-Osta, A. & Karagiannis, T. C., Jun 2011, In : Current Radiopharmaceuticals. 4, 1, p. 59-67 9 p.Research output: Contribution to journal › Review Article › Research › peer-review
12
Citations
(Scopus)
2010
γh2AX: A sensitive molecular marker of DNA damage and repair
Mah, L. J., El-Osta, A. & Karagiannis, T. C., Apr 2010, In : Leukemia. 24, 4, p. 679-686 8 p.Research output: Contribution to journal › Review Article › Research › peer-review
449
Citations
(Scopus)
γH2AX as a molecular marker of aging and disease
Mah, L. J., El-Osta, A. & Karagiannis, T. C., 2010, In : Epigenetics. 5, 2, p. 129-136 8 p.Research output: Contribution to journal › Review Article › Research › peer-review
68
Citations
(Scopus)
2007
Chromatin modifications and DNA double-strand breaks: The current state of play
Karagiannis, T. C. & El-Osta, A., 1 Jan 2007, In : Leukemia. 21, 2, p. 195-200 6 p.Research output: Contribution to journal › Review Article › Research › peer-review
32
Citations
(Scopus)
Will broad-spectrum histone deacetylase inhibitors be superseded by more specific compounds?
Karagiannis, T. C. & El-Osta, A., 1 Jan 2007, In : Leukemia. 21, 1, p. 61-65 5 p.Research output: Contribution to journal › Review Article › Research › peer-review
89
Citations
(Scopus)
2006
Clinical potential of histone deacetylase inhibitors as stand alone therapeutics and in combination with other chemotherapeutics or radiotherapy for cancer
Karagiannis, T. C. & El-Osta, A., 1 Jan 2006, In : Epigenetics. 1, 3, p. 121-126 6 p.Research output: Contribution to journal › Review Article › Research › peer-review
31
Citations
(Scopus)
Modulation of cellular radiation responses by histone deacetylase inhibitors
Karagiannis, T. C. & El-Osta, A., 29 Jun 2006, In : Oncogene. 25, 28, p. 3885-3893 9 p.Research output: Contribution to journal › Review Article › Research › peer-review
70
Citations
(Scopus)
The paradox of histone deacetylase inhibitor-mediated modulation of cellular responses to radiation
Karagiannis, T. C. & El-Osta, A., 1 Feb 2006, In : Cell Cycle. 5, 3, p. 288-295 8 p.Research output: Contribution to journal › Review Article › Research › peer-review
31
Citations
(Scopus)
2005
RNA interference and potential therapeutic applications of short interfering RNAs
Karagiannis, T. C. & El-Osta, A., 1 Oct 2005, In : Cancer Gene Therapy. 12, 10, p. 787-795 9 p.Research output: Contribution to journal › Review Article › Research › peer-review
108
Citations
(Scopus)
2004
Double-strand breaks: Signaling pathways and repair mechanisms
Karagiannis, T. C. & El-Osta, A., 1 Sep 2004, In : Cellular and Molecular Life Sciences. 61, 17, p. 2137-2147 11 p.Research output: Contribution to journal › Review Article › Research › peer-review
65
Citations
(Scopus)
Epigenetic changes activate widespread signals in response to double-strand breaks
Karagiannis, T. C. & El-Osta, A., 1 Jan 2004, In : Cancer Biology and Therapy. 3, 7, p. 617-623 7 p.Research output: Contribution to journal › Review Article › Research › peer-review
7
Citations
(Scopus)
siRNAs: Mechanism of RNA interference, in vivo and potential clinical applications
Karagiannis, T. C. & El-Osta, A., 1 Jan 2004, In : Cancer Biology and Therapy. 3, 11Research output: Contribution to journal › Review Article › Research › peer-review
26
Citations
(Scopus)