If you made any changes in Pure these will be visible here soon.

Research Output 2004 2017

Filter
Article
2017

Systems approach to the pharmacological actions of HDAC inhibitors reveals EP300 activities and convergent mechanisms of regulation in diabetes

Rafehi, H., Kaspi, A., Ziemann, M., Okabe, J., Karagiannis, T. C. & El-Osta, A., 2 Nov 2017, In : Epigenetics. 12, 11, p. 991-1003 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2016

Strand breakage by decay of DNA-bound 124I provides a basis for combined PET imaging and Auger endoradiotherapy

Lobachevsky, P., Clark, G. R., Pytel, P. D., Leung, B., Skene, C., Andrau, L., White, J. M., Karagiannis, T., Cullinane, C., Lee, B. Q., Stuchbery, A., Kibedi, T., Hicks, R. J. & Martin, R. F., 1 Nov 2016, In : International Journal of Radiation Biology. 92, 11, p. 686-697 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2015

Exploration of mechanisms in nutriepigenomics: Identification of chromatin-modifying compounds from Olea Europaea

Bonvino, N. P., Ray, N. B., Luu, V. T., Liang, J., Hung, A. & Karagiannis, T., Sep 2015, In : Hellenic Journal of Nuclear Medicine. 18, Suppl 1, p. 51-62 12 p.

Research output: Contribution to journalArticleResearchpeer-review

RNA sequencing supports distinct reactive oxygen species-mediated pathways of apoptosis by high and low size mass fractions of Bay leaf (Lauris nobilis) in HT-29 cells

Rodd, A. L., Ververis, K., Sayakkarage, D., Khan, A. W., Rafehi, H., Ziemann, M., Loveridge, S. J., Lazarus, R., Kerr, C. A., Lockett, T., El-Osta, A., Karagiannis, T. C. & Bennett, L. E., 2015, In : Food & Function: linking the chemistry and physics of food with health and nutrition. 6, 8, p. 2507-2524 18 p.

Research output: Contribution to journalArticleResearchpeer-review

2014

Biological effects of the olive polyphenol, hydroxytyrosol: An extra view from genome-wide transcriptome analysis

Ververis, K., Bollu, S., Rodd, A. L., Swarup, O., Karagiannis, T. & Nan, J. N., 2014, In : Journal of Nuclear Medicine. 17, Suppl 1, p. 62-69 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Cell cycle effects of L-sulforaphane, a major antioxidant from cruciferous vegetables: The role of the anaphase promoting complex

Li, Z. S., Royce, S. G., Ververis, K. & Karagiannis, T. C., 2014, In : Hellenic Journal of Nuclear Medicine. 17, p. 11-16 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Derivative of bardoxolone methyl, dh404, in an inverse dose-dependent manner lessens diabetes-Associated atherosclerosis and improves diabetic kidney disease

Tan, S. M., Sharma, A., Stefanovic, N., Yuen, D. Y. C., Karagiannis, T. C., Meyer, C., Ward, K. W., Cooper, M. E. & De Haan, J. B., Sep 2014, In : Diabetes. 63, 9, p. 3091-3103 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Histone deacetylase inhibitors potentiate photochemotherapy in cutaneous T-cell lymphoma MyLa cells

Sung, J. J., Ververis, K. & Karagiannis, T. C., 5 Feb 2014, In : Journal of Photochemistry and Photobiology B: Biology. 131, p. 104-112 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Oropharyngeal dysphagia, free water protocol and quality of life: An update from a prospective clinical trial

Karagiannis, M. & Karagiannis, T. C., Jan 2014, In : Journal of Nuclear Medicine. 17, Suppl 1, p. 26-29 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Vascular histone deacetylation by pharmacological HDAC inhibition

Rafehi, H., Balcerczyk, A., Lunke, S., Kaspi, A., Ziemann, M., Harikrishnan, K. N., Okabe, J., Khurana, I., Ooi, J., Khan, A. W., Du, X-J., Chang, L. H. C., Haviv, I., Keating, S. T., Karagiannis, T. & El-Osta, A., 2014, In : Genome Research. 24, 8, p. 1271-1284 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

Immunomodulatory effects of histone deacetylase inhibitors

Licciardi, P. V., Ververis, K., Tang, M. L., El-Osta, A. & Karagiannis, T. C., 2013, In : Current Molecular Medicine. 13, 4, p. 640-647 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2012

An atlas of histone deacetylase expression in breast cancer: Fluorescence methodology for comparative semi-quantitative analysis

Ververis, K. & Karagiannis, T. C., 2012, In : American Journal of Translational Research. 4, 1, p. 24-43 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Combination phototherapy with a histone deacetylase inhibitor and a potent DNA-binding bibenzimidazole: Effects in haematological cell lines

Rodd, A. L., Ververis, K. & Karagiannis, T., 2012, In : Lymphoma. 2012, 13 p., 405327.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Controversies surrounding the potential use of histone deacetylase Inhibitors for the treatment of asthma

Royce, S. G., Ververis, K. & Karagiannis, T. C., 2012, In : ISRN Pulmonology. 2012, 10 p., 452307.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
File

Current and emerging therapeutics for cutaneous T-Cell lymphoma: Histone deacetylase inhibitors

Rodd, A. L., Ververis, K. & Karagiannis, T. C., 2012, In : Lymphoma. 2012, 10 p., 290685.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Effects of the histone deacetylase inhibitor, trichostatin A, in a chronic allergic airways disease model in mice

Royce, S. G., Dang, W., Yuan, G. Y., Tran, J., El-Osta, A., Karagiannis, T. & Tang, M. L. K., Aug 2012, In : Archivum Immunologiae et Therapiae Experimentalis. 60, 4, p. 295-306 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Epigenetic mechanisms in the pathogenesis of diabetic foot ulcers

Rafehi, H., El-Osta, A. & Karagiannis, T. C., 2012, In : Journal of Diabetes and its Complications. 26, 6, p. 554-561 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Histone deacetylase inhibitors: can we consider potent anti-neoplastic agents for the treatment of asthma?

Royce, S. G., Ververis, K. & Karagiannis, T. C., 2012, In : Annals of Clinical and Laboratory Science. 42, 3, p. 338-345 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Histone deacetylases and their role in asthma

Royce, S. G. & Karagiannis, T. C., 2012, In : Journal of Asthma. 49, 2, p. 121 - 128 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Influence of natural and synthetic histone deacetylase inhibitors on chromatin

Licciardi, P. V., Kwa, F., Ververis, K., Di Costanzo, N., Balcerczyk, A., Tang, M. L., El-Osta, A. & Karagiannis, T. C., 2012, In : Antioxidants and Redox Signaling. 17, 2, p. 340-354 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Investigation into the biological properties of the olive polyphenol, hydroxytyrosol: mechanistic insights by genome-wide mRNA-Seq analysis

Rafehi, H., Smith, A. J., Balcerczyk, A., Ziemann, M., Ooi, J., Loveridge, S. J., Baker, E. K., El-Osta, A. & Karagiannis, T. C., 2012, In : Genes and Nutrition. 7, 2, p. 343-355 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Investigation of the biological properties of Cinnulin PF in the context of diabetes: mechanistic insights by genome-wide mRNA-Seq analysis

Rafehi, H., Ververis, K., Balcerczyk, A., Ziemann, M., Ooi, J., Hu, S., Kwa, F., Loveridge, S. J., Georgiadis, G. T., El-Osta, A. & Karagiannis, T., 2012, In : Pathobiology of Aging & Age-related Diseases. 2, 1, 14 p., 11905.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Molecular model of naphthalene-induced DNA damage in the murine lung

Karagiannis, T. C., Li, X., Tang, M. M., Orlowski, C., El-Osta, A., Tang, M. L. K. & Royce, S. G., 2012, In : Human and Experimental Toxicology. 31, 1, p. 42-50 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Overview of the classical histone deacetylase enzymes and histone deacetylase inhibitors

Ververis, K. & Karagiannis, T. C., 2012, In : ISRN Cell Biology. 2012, 12 p., 130360.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
File

Potential of chromatin modifying compounds for the treatment of Alzheimer's disease

Karagiannis, T. & Ververis, K., 20 Feb 2012, In : Pathobiology of Aging & Age-related Diseases. 2012, 2, p. 1-8 8 p., PMC3417541.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Regulation of immune responses by histone deacetylase inhibitors

Licciardi, P. V. & Karagiannis, T. C., 2012, In : ISRN Hematology. 2012, 10 p., 690901.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2011

Clonogenic assay: Adherent cells

Rafehi, H., Orlowski, C., Georgiadis, G. T., Ververis, K., El-Osta, A. & Karagiannis, T. C., Mar 2011, In : Journal of Visualized Experiments. 49, 4 p., e2573.

Research output: Contribution to journalArticleOtherpeer-review

Effects of oral intake of water in patients with oropharyngeal dysphagia

Karagiannis, M. JP., Chivers, L. & Karagiannis, T. C., Mar 2011, In : BMC Geriatrics. 11, 9.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Genetic and epigenetic events in diabetic wound healing

Rafehi, H., El-Osta, A. & Karagiannis, T. C., 2011, In : International Wound Journal. 8, 1, p. 12 - 21 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells

Pirola, L., Balcerczyk, A., Tothill, R. W., Haviv, I., Kaspi, A., Lunke, S., Ziemann, M., Karagiannis, T., Tonna, S., Kowalczyk, A., Beresford-Smith, B., Macintyre, G., Kelong, M., Hongyu, Z., Zhu, J. & El-Osta, A., Oct 2011, In : Genome Research. 21, 10, p. 1601-1615 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Histone deacetylase inhibition and dietary short-chain fatty acids

Licciardi, P. V., Ververis, K. & Karagiannis, T. C., 2011, In : ISRN Allergy. 2011, 8 p., 869647.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Histone deacetylase inhibitors augment doxorubicin-induced DNA damage in cardiomyocytes

Ververis, K., Rodd, A. L., Tang, M. M., El-Osta, A. & Karagiannis, T. C., Dec 2011, In : Cellular and Molecular Life Sciences. 68, 24, p. 4101-4114 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Photosensitization by iodinated DNA minor groove binding ligands: Evaluation of DNA double-strand break induction and repair

Briggs, B., Ververis, K., Rodd, A. L., Foong, L. J. L., Da Silva, F. M. & Karagiannis, T. C., 3 May 2011, In : Journal of Photochemistry and Photobiology B: Biology. 103, 2, p. 145-152 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Protective effects of valproic acid against airway hyperresponsiveness and airway remodeling in a mouse model of allergic airways disease

Royce, S. G., Dang, W., Ververis, K., De Sampayo, N., El-Osta, A., Tang, M. L. K. & Karagiannis, T. C., Dec 2011, In : Epigenetics. 6, 12, p. 1463 - 1470 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Resveratrol has protective effects against airway remodeling and airway hyperreactivity in a murine model of allergic airways disease

Royce, S. G., Dang, W., Yuan, G. Y., Tran, J., El-Osta, A., Karagiannis, T. & Tang, M. LK., 2011, In : Pathobiology of Aging & Age-related Diseases. 1, 10 p., 7134.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2010

Epigenome targeting by probiotic metabolites

Licciardi, P. V., Wong, S-S., Tang, M. L. K. & Karagiannis, T. C., 2010, In : Gut Pathogens. 2, 1, 24.

Research output: Contribution to journalArticleResearchpeer-review

Evaluation of the spatial distribution of γH2AX following ionizing radiation

Vasireddy, R. S., Tang, M. M., Mah, L-J., Georgiadis, G. T., El-Osta, A. & Karagiannis, T. C., Aug 2010, In : Journal of Visualized Experiments. 42, e2203.

Research output: Contribution to journalArticleResearchpeer-review

Quantification of γH2AX foci in response to Ionising radiation

Mah, L. J., Vasireddy, R. S., Tang, M. M., Georgiadis, G. T., El-Osta, A. & Karagiannis, T. C., Apr 2010, In : Journal of Visualized Experiments. 38, e1957.

Research output: Contribution to journalArticleResearchpeer-review

Quantitation of gammaH2AX Foci in Tissue Samples

Tang, M. M., Mah, L-J., Vasireddy, R. S., Georgiadis, G. T., El-Osta, A., Royce, S. G. & Karagiannis, T., 2010, In : Journal of Visualized Experiments. 2010, 40, p. 1 - 3 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Trichostatin A accentuates doxorubicin-induced hypertrophy in cardiac myocytes

Karagiannis, T. C., Lin, A. J. E., Ververis, K., Chang, L., Tang, M. M., Okabe, J. & El-Osta, A., Oct 2010, In : Aging. 2, 10, p. 659-668 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

γ-radiation-induced γh2AX formation occurs preferentially in actively transcribing euchromatic loci

Vasireddy, R. S., Karagiannis, T. C. & El-Osta, A., Jan 2010, In : Cellular and Molecular Life Sciences. 67, 2, p. 291-294 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2008

Effect of valproic acid on radiation-induced DNA damage in euchromatic and heterochromatic compartments

Harikrishnan, K. N., Karagiannis, T. C., Chow, M. Z. & El-Osta, A., 15 Feb 2008, In : Cell Cycle. 7, 4, p. 468-476 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2007

Disparity of histone deacetylase inhibition on repair of radiation-induced DNA damage on euchromatin and constitutive heterochromatin compartments

Karagiannis, T. C., Kn, H. & El-Osta, A., 7 Jun 2007, In : Oncogene. 26, 27, p. 3963-3971 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2006

The epigenetic modifier, valproic acid, enhances radiation sensitivity

Karagiannis, T. C., Kn, H. & El-Osta, A., 1 Jan 2006, In : Epigenetics. 1, 3, p. 131-137 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2005

The histone deacetylase inhibitor, trichostatin A, enhances radiation sensitivity and accumulation of γH2A.X

Karagiannis, T. C., Harikrishnan, K. N. & El-Osta, A., 1 Jan 2005, In : Cancer Biology and Therapy. 4, 7, p. 787-793 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2004

Radio- and chemo-sensitization of human erythroleukemic K562 cells by the histone deacetylase inhibitor Trichostatin A

Karagiannis, T. C., Smith, A. J. & El'Osta, A., 1 Sep 2004, In : Medicine, Science and the Law. 7, 3, p. 184-191 8 p.

Research output: Contribution to journalArticleResearchpeer-review