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Research Output 2004 2017

2010

Evaluation of the spatial distribution of γH2AX following ionizing radiation

Vasireddy, R. S., Tang, M. M., Mah, L-J., Georgiadis, G. T., El-Osta, A. & Karagiannis, T. C., Aug 2010, In : Journal of Visualized Experiments. 42, e2203.

Research output: Contribution to journalArticleResearchpeer-review

Quantification of γH2AX foci in response to Ionising radiation

Mah, L. J., Vasireddy, R. S., Tang, M. M., Georgiadis, G. T., El-Osta, A. & Karagiannis, T. C., Apr 2010, In : Journal of Visualized Experiments. 38, e1957.

Research output: Contribution to journalArticleResearchpeer-review

Quantitation of gammaH2AX Foci in Tissue Samples

Tang, M. M., Mah, L-J., Vasireddy, R. S., Georgiadis, G. T., El-Osta, A., Royce, S. G. & Karagiannis, T., 2010, In : Journal of Visualized Experiments. 2010, 40, p. 1 - 3 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Trichostatin A accentuates doxorubicin-induced hypertrophy in cardiac myocytes

Karagiannis, T. C., Lin, A. J. E., Ververis, K., Chang, L., Tang, M. M., Okabe, J. & El-Osta, A., Oct 2010, In : Aging. 2, 10, p. 659-668 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

γh2AX: A sensitive molecular marker of DNA damage and repair

Mah, L. J., El-Osta, A. & Karagiannis, T. C., Apr 2010, In : Leukemia. 24, 4, p. 679-686 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

γH2AX as a molecular marker of aging and disease

Mah, L. J., El-Osta, A. & Karagiannis, T. C., 2010, In : Epigenetics. 5, 2, p. 129-136 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

γ-radiation-induced γh2AX formation occurs preferentially in actively transcribing euchromatic loci

Vasireddy, R. S., Karagiannis, T. C. & El-Osta, A., Jan 2010, In : Cellular and Molecular Life Sciences. 67, 2, p. 291-294 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2008

Effect of valproic acid on radiation-induced DNA damage in euchromatic and heterochromatic compartments

Harikrishnan, K. N., Karagiannis, T. C., Chow, M. Z. & El-Osta, A., 15 Feb 2008, In : Cell Cycle. 7, 4, p. 468-476 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2007

Chromatin modifications and DNA double-strand breaks: The current state of play

Karagiannis, T. C. & El-Osta, A., 1 Jan 2007, In : Leukemia. 21, 2, p. 195-200 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Disparity of histone deacetylase inhibition on repair of radiation-induced DNA damage on euchromatin and constitutive heterochromatin compartments

Karagiannis, T. C., Kn, H. & El-Osta, A., 7 Jun 2007, In : Oncogene. 26, 27, p. 3963-3971 9 p.

Research output: Contribution to journalArticleResearchpeer-review

DNA double-strand breaks repair pathways in the framework of chromatin

Karagiannis, T. C. & El-Osta, A., 1 Dec 2007, New Research on DNA Repair. Nova Science Publishers, p. 295-324 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Will broad-spectrum histone deacetylase inhibitors be superseded by more specific compounds?

Karagiannis, T. C. & El-Osta, A., 1 Jan 2007, In : Leukemia. 21, 1, p. 61-65 5 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2006

Clinical potential of histone deacetylase inhibitors as stand alone therapeutics and in combination with other chemotherapeutics or radiotherapy for cancer

Karagiannis, T. C. & El-Osta, A., 1 Jan 2006, In : Epigenetics. 1, 3, p. 121-126 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Modulation of cellular radiation responses by histone deacetylase inhibitors

Karagiannis, T. C. & El-Osta, A., 29 Jun 2006, In : Oncogene. 25, 28, p. 3885-3893 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

The epigenetic modifier, valproic acid, enhances radiation sensitivity

Karagiannis, T. C., Kn, H. & El-Osta, A., 1 Jan 2006, In : Epigenetics. 1, 3, p. 131-137 7 p.

Research output: Contribution to journalArticleResearchpeer-review

The paradox of histone deacetylase inhibitor-mediated modulation of cellular responses to radiation

Karagiannis, T. C. & El-Osta, A., 1 Feb 2006, In : Cell Cycle. 5, 3, p. 288-295 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2005

RNA interference and potential therapeutic applications of short interfering RNAs

Karagiannis, T. C. & El-Osta, A., 1 Oct 2005, In : Cancer Gene Therapy. 12, 10, p. 787-795 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

The histone deacetylase inhibitor, trichostatin A, enhances radiation sensitivity and accumulation of γH2A.X

Karagiannis, T. C., Harikrishnan, K. N. & El-Osta, A., 1 Jan 2005, In : Cancer Biology and Therapy. 4, 7, p. 787-793 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2004

Double-strand breaks: Signaling pathways and repair mechanisms

Karagiannis, T. C. & El-Osta, A., 1 Sep 2004, In : Cellular and Molecular Life Sciences. 61, 17, p. 2137-2147 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Epigenetic changes activate widespread signals in response to double-strand breaks

Karagiannis, T. C. & El-Osta, A., 1 Jan 2004, In : Cancer Biology and Therapy. 3, 7, p. 617-623 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Radio- and chemo-sensitization of human erythroleukemic K562 cells by the histone deacetylase inhibitor Trichostatin A

Karagiannis, T. C., Smith, A. J. & El'Osta, A., 1 Sep 2004, In : Medicine, Science and the Law. 7, 3, p. 184-191 8 p.

Research output: Contribution to journalArticleResearchpeer-review

siRNAs: Mechanism of RNA interference, in vivo and potential clinical applications

Karagiannis, T. C. & El-Osta, A., 1 Jan 2004, In : Cancer Biology and Therapy. 3, 11

Research output: Contribution to journalReview ArticleResearchpeer-review