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Research Output 2004 2017

2017

Pharmacological histone deacetylation distinguishes transcriptional regulators

Rafehi, H., Karagiannis, T. C. & El-Osta, A., 1 May 2017, In : Current Topics in Medicinal Chemistry. 17, 14, p. 1611 - 1622 12 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Systems approach to the pharmacological actions of HDAC inhibitors reveals EP300 activities and convergent mechanisms of regulation in diabetes

Rafehi, H., Kaspi, A., Ziemann, M., Okabe, J., Karagiannis, T. C. & El-Osta, A., 2 Nov 2017, In : Epigenetics. 12, 11, p. 991-1003 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2016

Strand breakage by decay of DNA-bound 124I provides a basis for combined PET imaging and Auger endoradiotherapy

Lobachevsky, P., Clark, G. R., Pytel, P. D., Leung, B., Skene, C., Andrau, L., White, J. M., Karagiannis, T., Cullinane, C., Lee, B. Q., Stuchbery, A., Kibedi, T., Hicks, R. J. & Martin, R. F., 1 Nov 2016, In : International Journal of Radiation Biology. 92, 11, p. 686-697 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2015

Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K

Courtnay, R., Ngo, D. C., Malik, N., Ververis, K., Tortorella, S. M. & Karagiannis, T. C., 1 Apr 2015, In : Molecular Biology Reports. 42, 4, p. 841-851 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Cellular and Molecular Effects of Bioactive Phenolic Compounds in Olives and Olive Oil

Ray, N. B., Lam, N. T., Luc, R., Bonvino, N. P. & Karagiannis, T. C., 15 Apr 2015, Olive and Olive Oil Bioactive Constituents. Boskou, D. (ed.). Netherlands: Elsevier, p. 53-91 39 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Exploration of mechanisms in nutriepigenomics: Identification of chromatin-modifying compounds from Olea Europaea

Bonvino, N. P., Ray, N. B., Luu, V. T., Liang, J., Hung, A. & Karagiannis, T., Sep 2015, In : Hellenic Journal of Nuclear Medicine. 18, Suppl 1, p. 51-62 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Introduction to the molecular basis of cancer metabolism and the Warburg effect

Ngo, D. C., Ververis, K., Tortorella, S. M. & Karagiannis, T. C., 1 Apr 2015, In : Molecular Biology Reports. 42, 4, p. 819-823 5 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Lactate as an insidious metabolite due to the Warburg effect

Luc, R., Tortorella, S. M., Ververis, K. & Karagiannis, T. C., 1 Apr 2015, In : Molecular Biology Reports. 42, 4, p. 835-840 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Regulation of inflammatory gene expression by histone acetylation and HDAC inhibition in human aortic endothelial cells

Rafehi, H., Balcerczyk, A., Lunke, S., Kaspi, A. D., Ziemann, M., Kaipananickal, H., Okabe, J., Khurana, I., Ooi, J., Khan, A. W., Du, X-J., Chang, L., Haviv, I., Keating, S. T., Karagiannis, T. & El-Osta, S., 2015, In : Atherosclerosis. 241, 1, p. e6 1 p.

Research output: Contribution to journalMeeting AbstractOtherpeer-review

Open Access

RNA sequencing supports distinct reactive oxygen species-mediated pathways of apoptosis by high and low size mass fractions of Bay leaf (Lauris nobilis) in HT-29 cells

Rodd, A. L., Ververis, K., Sayakkarage, D., Khan, A. W., Rafehi, H., Ziemann, M., Loveridge, S. J., Lazarus, R., Kerr, C. A., Lockett, T., El-Osta, A., Karagiannis, T. C. & Bennett, L. E., 2015, In : Food & Function: linking the chemistry and physics of food with health and nutrition. 6, 8, p. 2507-2524 18 p.

Research output: Contribution to journalArticleResearchpeer-review

The Anti-Diabetic Effects of Polyphenols from Olea Europaea (OE)

Ray, N. B., Karagiannis, T. & McCord, E., 2015, 8 p. McCord Research.

Research output: Other contributionOther

The Beneficial Effects of Olivamine on Brain Health

Ray, N. B., Karagiannis, T. & McCord, E., 2015, 8 p. McCord Research.

Research output: Other contributionOther

The early life origin theory in the development of cardiovascular disease and type 2 diabetes

Lindblom, R., Ververis, K., Tortorella, S. M. & Karagiannis, T. C., 1 Apr 2015, In : Molecular Biology Reports. 42, 4, p. 791-797 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

The Implication of Cancer Progenitor Cells and the Role of Epigenetics in the Development of Novel Therapeutic Strategies for Chronic Myeloid Leukemia

Tortorella, S. M., Hung, A. & Karagiannis, T. C., 1 Jun 2015, In : Antioxidants and Redox Signaling. 22, 16, p. 1425-1462 38 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

The Warburg effect: molecular aspects and therapeutic possibilities

Ngo, H., Tortorella, S. M., Ververis, K. & Karagiannis, T. C., 1 Apr 2015, In : Molecular Biology Reports. 42, 4, p. 825-834 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2014

An overview of epigenetic mechanisms in health and disease

Westerland, C. & Karagiannis, T., 1 Feb 2014, Molecular Mechanisms and Physiology of Disease: Implications for Epigenetics and Health. Maulik, N. & Karagiannis, T. (eds.). Springer, p. 81-112 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Anti-inflammatory effects of probiotics and their metabolites: Possible role for epigenetic effects

Türker, N., Toh, Z. Q., Karagiannis, T. C. & Licciardi, P. V., 18 Apr 2014, Molecular Mechanisms and Physiology of Disease: Implications for Epigenetics and Health. Maulik, N. & Karagiannis, T. (eds.). New York: Springer, p. 127-150 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Biological effects of the olive polyphenol, hydroxytyrosol: An extra view from genome-wide transcriptome analysis

Ververis, K., Bollu, S., Rodd, A. L., Swarup, O., Karagiannis, T. & Nan, J. N., 2014, In : Journal of Nuclear Medicine. 17, Suppl 1, p. 62-69 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Cell cycle effects of L-sulforaphane, a major antioxidant from cruciferous vegetables: The role of the anaphase promoting complex

Li, Z. S., Royce, S. G., Ververis, K. & Karagiannis, T. C., 2014, In : Hellenic Journal of Nuclear Medicine. 17, p. 11-16 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Combination therapy for cancer: Phototherapy and HDAC inhibition

Sung, J. J. & Karagiannis, T. C., 1 Feb 2014, Molecular Mechanisms and Physiology of Disease: Implications for Epigenetics and Health. Maulik, N. & Karagiannis, T. (eds.). New York: Springer, p. 445-470 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Derivative of bardoxolone methyl, dh404, in an inverse dose-dependent manner lessens diabetes-Associated atherosclerosis and improves diabetic kidney disease

Tan, S. M., Sharma, A., Stefanovic, N., Yuen, D. Y. C., Karagiannis, T. C., Meyer, C., Ward, K. W., Cooper, M. E. & De Haan, J. B., Sep 2014, In : Diabetes. 63, 9, p. 3091-3103 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Dietary antioxidants and chromatin modifying compounds as potential anti-cancer therapies

Mazarakis, N. & Karagiannis, T. C., 1 Feb 2014, Molecular Mechanisms and Physiology of Disease: Implications for Epigenetics and Health. Maulik, N. & Karagiannis, T. (eds.). New York: Springer, p. 427-444 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Histone deacetylase inhibitors potentiate photochemotherapy in cutaneous T-cell lymphoma MyLa cells

Sung, J. J., Ververis, K. & Karagiannis, T. C., 5 Feb 2014, In : Journal of Photochemistry and Photobiology B: Biology. 131, p. 104-112 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Molecular aspects of the Warburg effect

Balding, E., Ververis, K. & Karagiannis, T. C., 1 Feb 2014, Molecular Mechanisms and Physiology of Disease: Implications for Epigenetics and Health. Maulik, N. & Karagiannis, T. (eds.). New York: Springer, p. 371-382 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Molecular mechanisms and physiology of disease: Implications for epigenetics and health

Maulik, N. (ed.) & Karagiannis, T. (ed.), 1 Feb 2014, New York: Springer. 505 p.

Research output: Book/ReportEdited BookOtherpeer-review

Molecular mechanisms in the development and progression of asthma: The role of epigenetic regulation and the airway epithelium

Tortorella, S., Royce, S. G. & Karagiannis, T. C., 1 Feb 2014, Molecular Mechanisms and Physiology of Disease: Implications for Epigenetics and Health. Maulik, N. & Karagiannis, T. (eds.). New York NY USA: Springer, p. 219-245 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Nano-based drug delivery modalities for the treatment of cancer: The formulation of tumour-specific and-targeted nanoparticles

Mah, L. J., Tortorella, S. & Karagiannis, T. C., 1 Feb 2014, Molecular Mechanisms and Physiology of Disease: Implications for Epigenetics and Health. Maulik, N. & Karagiannis, T. (eds.). New York: Springer, p. 471-501 31 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Oropharyngeal dysphagia, free water protocol and quality of life: An update from a prospective clinical trial

Karagiannis, M. & Karagiannis, T. C., Jan 2014, In : Journal of Nuclear Medicine. 17, Suppl 1, p. 26-29 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Preface

Maulik, N. & Karagiannis, T. C., 18 Apr 2014, Molecular Mechanisms and Physiology of Disease: Implications for Epigenetics and Health. Maulik, N. & Karagiannis, T. (eds.). New York NY USA: Springer, p. vii - x 4 p.

Research output: Chapter in Book/Report/Conference proceedingForeword / PostscriptOtherpeer-review

Preface

Maulik, N. & Karagiannis, T., 1 Feb 2014, Molecular Mechanisms and Physiology of Disease: Implications for Epigenetics and Health. Springer, p. vii-x

Research output: Chapter in Book/Report/Conference proceedingForeword / PostscriptOtherpeer-review

Principles of the Warburg effect and cancer cell metabolism

Molino, N., Ververis, K. & Karagiannis, T. C., 1 Feb 2014, Molecular Mechanisms and Physiology of Disease: Implications for Epigenetics and Health. Maulik, N. & Karagiannis, T. (eds.). New York: Springer, p. 355-369 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

The Angiogenic and Bioenergetic Effects of the McCord Compound

Karagiannis, T., Ray, N. B. & McCord, E., 2014, 4 p. McCord Research.

Research output: Other contributionOther

The significance of nanoparticles in medicine and their potential application in asthma

Tortorella, S. & Karagiannis, T. C., 1 Feb 2014, Molecular Mechanisms and Physiology of Disease: Implications for Epigenetics and Health. Maulik, N. & Karagiannis, T. (eds.). New York: Springer, p. 247-275 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

The significance of transferrin receptors in oncology: The development of functional nano-based drug delivery systems

Tortorella, S. & Karagiannis, T. C., 2014, In : Current Drug Delivery. 11, 4, p. 427-443 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

The timeless influence of Hippocratic ideas on diet, salicylates and personalized medicine

Karagiannis, T. C., 2014, In : Hellenic Journal of Nuclear Medicine. 17, 1, p. 2-6 5 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Transferrin receptor-mediated endocytosis: A useful target for cancer therapy

Tortorella, S. & Karagiannis, T. C., 2014, In : Journal of Membrane Biology. 247, 4, p. 291-307 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Vascular histone deacetylation by pharmacological HDAC inhibition

Rafehi, H., Balcerczyk, A., Lunke, S., Kaspi, A., Ziemann, M., Harikrishnan, K. N., Okabe, J., Khurana, I., Ooi, J., Khan, A. W., Du, X-J., Chang, L. H. C., Haviv, I., Keating, S. T., Karagiannis, T. & El-Osta, A., 2014, In : Genome Research. 24, 8, p. 1271-1284 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

Attenuation of myocardial ischemia-reperfusion injury by probiotic bacteria

Licciardi, P. V., Ververis, K., Toh, Z. Q. & Karagiannis, T. C., 2013, Cardiovascular Diseases: Nutritional and Therapeutic Interventions. Maulik, N. (ed.). CRC Press, p. 61-74 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Genetic and epigenetic basis of myocardial ischemia and reperfusion injury: Protection by dietary antioxidants and chromatin-modifying compounds

Karagiannis, T. C., Ververis, K. & Licciardi, P. V., 2013, Cardiovascular Diseases: Nutritional and Therapeutic Interventions. Maulik, N. (ed.). CRC Press, p. 35-59 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Histone deacetylase inhibitors (HDACIS): Multitargeted anticancer agents

Ververis, K., Hiong, A., Karagiannis, T. C. & Licciardi, P. V., 23 Feb 2013, In : Biologics: Targets and Therapy. 7, 1, p. 47-60 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

Immunomodulatory effects of histone deacetylase inhibitors

Licciardi, P. V., Ververis, K., Tang, M. L., El-Osta, A. & Karagiannis, T. C., 2013, In : Current Molecular Medicine. 13, 4, p. 640-647 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Preface

Maulik, N. & Karagiannis, T., 2013, Cardiovascular Diseases: Nutritional and Therapeutic Interventions. Maulik, N. (ed.). CRC Press, p. xv - xvii 3 p.

Research output: Chapter in Book/Report/Conference proceedingForeword / PostscriptOtherpeer-review

The potential role of HDAC inhibitors in de-silencing latent HIV virus

Ververis, K. & Karagiannis, T. C., 2013, In : Drugs of the Future. 38, 8, p. 575-583 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2012

Aetiology and pathogenesis of chronic leukaemias

Kwa, F. AA. & Karagiannis, T. C., 2012, Epigenomic Medicine II – Haematological Malignancies. Karagiannis, T. C. & Kwa, F. A. A. (eds.). Kerala, India: Transworld Research Network, p. 21-29 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

An atlas of histone deacetylase expression in breast cancer: Fluorescence methodology for comparative semi-quantitative analysis

Ververis, K. & Karagiannis, T. C., 2012, In : American Journal of Translational Research. 4, 1, p. 24-43 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Combination phototherapy with a histone deacetylase inhibitor and a potent DNA-binding bibenzimidazole: Effects in haematological cell lines

Rodd, A. L., Ververis, K. & Karagiannis, T., 2012, In : Lymphoma. 2012, 13 p., 405327.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Controversies surrounding the clinical potential of cinnamon for the management of diabetes

Rafehi, H., Ververis, K. & Karagiannis, T. C., Jun 2012, In : Diabetes, Obesity and Metabolism. 14, 6, p. 493-499 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review