Personal profile


Dr Merson completed his PhD at the Walter & Eliza Hall Institute for Medical Research in 2006, demonstrating the critical role of epigenetics in the regulation of neural stem cell function and adult neurogenesis. He then took up a postdoctoral position within the Multiple Sclerosis Group at the Howard Florey Institute and was awarded a Betty Cuthbert Training Fellowship (2007-2010) jointly funded by the NHMRC and Multiple Sclerosis Research Australia. In 2013, he established his own laboratory within the Multiple Sclerosis Division at the Florey Institute of Neuroscience and Mental Health and in the same year, was awarded a Melbourne Neuroscience Institute Fellowship. In 2016, he was awarded an ARC Future Fellowship and appointed Group Leader in MS Research at the Australian Regenerative Medicine Institute, Monash Univerity. His research examines the life cycle of the oligodendrocyte, the cell type responsible for myelination within the central nervous system focusing on how oligodendrocytes are generated during development, how they are regenerated after injury and their role in supporting the function of axons.


  • Myelination
  • Oligodendrocytes
  • Multiple Sclerosis (MS)
  • Neural stem cell
  • Remyelination
  • Axonal degeneration
  • Demyelination
  • Oligodendrocyte progenitor cells (OPCs)
  • Neural Plasticity

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Projects 2014 2022

Research Output 2004 2016

Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory

Martin, K., Corlett, A., Dubach, D., Mustafa, T., Coleman, H. A., Parkington, H. C., Merson, T. D., Bourne, J. A., Porta, S., Arbones, M. L., Finkelstein, D. I. & Pritchard, M. A. 2012 In : Human Molecular Genetics. 21, 13, p. 3025 - 3041 17 p.

Research output: Research - peer-reviewArticle

Open Access

Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome

Hewitt, C. A., Ling, K. -H., Merson, T. D., Simpson, K. M., Ritchie, M. E., King, S. L., Pritchard, M. A., Smyth, G. K., Thomas, T., Scott, H. S. & Voss, A. K. 2010 In : PLoS ONE. 5, 7 (Art. No: e11561), p. 1 - 15 15 p.

Research output: Research - peer-reviewArticle