Tin Soe Kyaw &ndash; Research Output

2010

Conventional B2 B cell depletion ameliorates whereas its adoptive transfer aggravates atherosclerosis

Kyaw, T., Tay, C., Khan, A., Dumouchel, V., Cao, A., To, K., Kehry, M., Dunn, R., Agrotis, A., Tipping, P., Bobik, A. & Toh, B-H., 2010, In : Journal of Immunology. 185, 7, p. 4410 - 4419 10 p.

Research output: Contribution to journal › Article › Research › peer-review

2011

170 Citations (Scopus)

B1a B lymphocytes are atheroprotective by secreting natural IgM that increases IgM deposits and reduces necrotic cores in atherosclerotic lesions

Kyaw, T., Tay, C., Krishnamurthi, S., Kanellakis, P., Agrotis, A., Tipping, P., Bobik, A. & Toh, B-H., 2011, In : Circulation Research. 109, 8, p. 830 - 840 11 p.

Research output: Contribution to journal › Article › Research › peer-review

40 Citations (Scopus)

Current understanding of the role of B cell subsets and intimal and adventitial B cells in atherosclerosis

Kyaw, T., Tipping, P., Toh, B-H. & Bobik, A., 2011, In : Current Opinion in Lipidology. 22, 5, p. 373 - 379 7 p.

Research output: Contribution to journal › Article › Research › peer-review

2012

86 Citations (Scopus)

Cytokine therapy with interleukin-2/anti-interleukin-2 monoclonal antibody complexes expands CD4+CD25+Foxp3+ regulatory T cells and attenuates development and progression of atherosclerosis

Dinh, T. N., Kyaw, T. S., Kanellakis, P., To, K. Y-Y., Tipping, P. G., Toh, B-H., Bobik, A. & Agrotis, A., 2012, In : Circulation. 126, 10, p. 1256 - 1266 11 p.

Research output: Contribution to journal › Article › Research › peer-review

92 Citations (Scopus)

Depletion of B2 but not B1a B cells in BAFF receptor-deficient ApoE-/- mice attenuates atherosclerosis by potently ameliorating arterial inflammation

Kyaw, T. S., Tay, C., Hosseini, H., Kanellakis, P., Gadowski, T., Mackay-Fisson, F., Tipping, P. G., Bobik, A. & Toh, B-H., 2012, In : PLoS ONE. 7, 1, 10 p., e29371.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

14 Citations (Scopus)

Parietal cell antibody identified by ELISA is superior to immunofluorescence, rises with age and is associated with intrinsic factor antibody

Toh, B-H., Kyaw, T. S., Taylor, R., Pollock, W. & Schlumberger, W., 2012, In : Autoimmunity. 45, 7, p. 527 - 532 6 p.

Research output: Contribution to journal › Article › Research › peer-review

37 Citations (Scopus)

Protective role of natural IgM-producing B1a cells in atherosclerosis

Kyaw, T. S., Tipping, P. G., Bobik, A. & Toh, B-H., 2012, In : Trends in Cardiovascular Medicine. 22, 2, p. 48 - 53 6 p.

Research output: Contribution to journal › Article › Research › peer-review

2013

42 Citations (Scopus)

BAFF receptor mAb treatment ameliorates development and progression of atherosclerosis in hyperlipidemic ApoE{-/-} mice

Kyaw, T. S., Cui, P., Tay, C., Kanellakis, P., Hosseini, H., Liu, E., Rolink, A. G., Tipping, P. G., Bobik, A. & Toh, B-H., 2013, In : PLoS ONE. 8, 4 (Art. ID: e60430), p. 1 - 12 12 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

105 Citations (Scopus)

Cytotoxic and proinflammatory CD8⁺ T lymphocytes promote development of vulnerable atherosclerotic plaques in ApoE-deficient mice

Kyaw, T., Winship, A., Tay, C., Kanellakis, P., Hosseini, H., Cao, A., Li, P., Tipping, P., Bobik, A. & Toh, B-H., 5 Mar 2013, In : Circulation. 127, 9, p. 1028 - 1039 12 p.

Research output: Contribution to journal › Article › Research › peer-review

2014

14 Citations (Scopus)

Antibodies in the pathogenesis of hypertension

Chan, C., Lieu, M., Toh, B-H., Kyaw, T. S., Bobik, A., Sobey, C. G. & Drummond, G. R., 2014, In : BioMed Research International. 2014, (Art. No: 504045), p. 1 - 9 9 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

39 Citations (Scopus)

Natural killer (NK) cells augment atherosclerosis by cytotoxic-dependent mechanisms

Selathurai, A., Deswaerte, V., Kanellakis, P., Tipping, P. G., Toh, B-H., Bobik, A. & Kyaw, T. S., 2014, In : Cardiovascular Research. 102, 1, p. 128 - 137 10 p.

Research output: Contribution to journal › Article › Research › peer-review

42 Citations (Scopus)

Protective role for Toll-like receptor-9 in the development of atherosclerosis in apolipoprotein E-deficient mice

Koulis, C., Chen, Y-C., Hausding, C., Ahrens, I., Kyaw, T. S., Tay, C., Allen, T. J., Jandeleit-Dahm, K. A. M., Sweet, M. J., Akira, S., Bobik, A., Peter, K. & Agrotis, A., 2014, In : Arteriosclerosis, Thrombosis and Vascular Biology. 34, 3, p. 516 - 525 10 p.

Research output: Contribution to journal › Article › Research › peer-review

2015

27 Citations (Scopus)

CD4+ natural killer T cells potently augment aortic root atherosclerosis by perforin- and granzyme B-dependent cytotoxicity

Li, Y., To, K., Kanellakis, P., Hosseini, H., Deswaerte, V., Tipping, P. G., Smyth, M. J., Toh, B-H., Bobik, A. & Kyaw, T. S., 2015, In : Circulation Research. 116, 2, p. 245 - 254 10 p.

Research output: Contribution to journal › Article › Research › peer-review

68 Citations (Scopus)

Obligatory role for B cells in the development of angiotensin II-dependent hypertension

Chan, C. T-L., Sobey, C. G., Lieu, M., Ferens, D. M., Kett, M. M., Diep, H., Kim, H. H. A., Krishnan, S. M., Lewis, C. V., Salimova, E., Tipping, P. G., Vinh, A., Samuel, C. S., Peter, K., Guzik, T. J., Kyaw, T. S., Toh, B-H., Bobik, A. & Drummond, G. R., 2015, In : Hypertension. 66, 5, p. 1023 - 1033 11 p.

Research output: Contribution to journal › Article › Research › peer-review

40 Citations (Scopus)

Phosphatidylserine liposomes mimic apoptotic cells to attenuate atherosclerosis by expanding polyreactive IgM producing B1a lymphocytes

Hosseini, H., Li, Y., Kanellakis, P., Tay, C., Cao, A., Tipping, P. G., Bobik, A., Toh, B-H. & Kyaw, T. S., 2015, In : Cardiovascular Research. 106, 3, p. 443 - 452 10 p.

Research output: Contribution to journal › Article › Research › peer-review

2016

18 Citations (Scopus)

A CD1d-dependent lipid antagonist to NKT cells ameliorates atherosclerosis in ApoE^-/- mice by reducing lesion necrosis and inflammation

Li, Y., Kanellakis, P., Hosseini, H., Cao, A., Deswaerte, V., Tipping, P., Toh, B. H., Bobik, A. & Kyaw, T., 1 Feb 2016, In : Cardiovascular Research. 109, 2, p. 305-317 13 p.

Research output: Contribution to journal › Article › Research › peer-review

18 Citations (Scopus)

Atherosclerotic Plaque Rupture: Identifying the Straw That Breaks the Camel?s Back

Chen, Y. C., Huang, A. L., Kyaw, T. S., Bobik, A. & Peter, K., 1 Aug 2016, In : Arteriosclerosis, Thrombosis and Vascular Biology. 36, 8, p. e63-e72

Research output: Contribution to journal › Article › Other › peer-review

22 Citations (Scopus)

B-cell-specific depletion of tumour necrosis factor alpha inhibits atherosclerosis development and plaque vulnerability to rupture by reducing cell death and inflammation

Tay, C., Liu, Y. H., Hosseini, H., Kanellakis, P., Cao, A., Peter, K., Tipping, P., Bobik, A., Toh, B. H. & Kyaw, T., 1 Sep 2016, In : Cardiovascular Research. 111, 4, p. 385-397 13 p.

Research output: Contribution to journal › Article › Research › peer-review

2017

3 Citations (Scopus)

Killer cells in atherosclerosis

Kyaw, T., Tipping, P., Toh, B-H. & Bobik, A., 5 Dec 2017, In : European Journal of Pharmacology. 816, p. 67-75

Research output: Contribution to journal › Article › Research › peer-review