1985 …2022

Research output per year

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2020

Glucocorticoid signalling drives reduced versican levels in the fetal mouse lung

Short, K. L., Bird, A. D., Seow, B. K. L., Ng, J., McDougall, A. R. A., Wallace, M. J., Hooper, S. B. & Cole, T. J., Apr 2020, In : Journal of Molecular Endocrinology. 64, 3, p. 155-164 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2019

Identification of Betamethasone-Regulated Target Genes and Cell Pathways in Fetal Rat Lung Mesenchymal Fibroblasts

Seow, B. K. L., McDougall, A. R. A., Short, K. L., Wallace, M. J., Hooper, S. B. & Cole, T. J., 1 Aug 2019, In : Endocrinology. 160, 8, p. 1868-1884 17 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

The science of steroids

Cole, T. J., Short, K. L. & Hooper, S. B., 1 Jun 2019, In : Seminars in Fetal and Neonatal Medicine. 24, 3, p. 170-175 6 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)
2018

Glucocorticoids influence versican and chondroitin sulphate proteoglycan levels in the fetal sheep lung

McDougall, A. R. A., Fosang, A. J., Faggian, J., Wallace, M. J., Crossley, K. J., Cole, T. J. & Hooper, S. B., 20 Aug 2018, In : Respiratory Research. 19, 1, 12 p., 155.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2 Citations (Scopus)
2017

30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Mineralocorticoid receptor null mice: Informing cell-type-specific roles

Cole, T. J. & Young, M. J., 1 Jul 2017, In : Journal of Endocrinology. 234, 1, p. T83-T92 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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10 Citations (Scopus)

Fresh Noncultured Endothelial Progenitor Cells Improve Neonatal Lung Hyperoxia-Induced Alveolar Injury

Firsova, A. B., Bird, A. D., Abebe, D., Ng, J., Mollard, R. & Cole, T. J., 1 Dec 2017, In : Stem Cells Translational Medicine. 6, 12, p. 2094-2105 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

Hydroxysteroid dehydrogenase HSD1L is localised to the pituitary-gonadal axis of primates

Bird, A. D., Greatorex, S., Reser, D., Lavery, G. & Cole, T. J., 1 Oct 2017, In : Endocrine Connections. 6, 7, p. 489-499 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2 Citations (Scopus)

In vivo evidence that RBM5 is a tumour suppressor in the lung

Jamsai, D., Watkins, D. N., O'Connor, A. E., Merriner, D. J., Gursoy, S., Bird, A. D., Kumar, B., Miller, A., Cole, T. J., Jenkins, B. J. & O'Bryan, M. K., 1 Dec 2017, In : Scientific Reports. 7, 1, 8 p., 15874.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Review: The role of multiple placental glucocorticoid receptor isoforms in adapting to the maternal environment and regulating fetal growth

Clifton, V. L., Cuffe, J., Moritz, K. M., Cole, T. J., Fuller, P. J., Lu, N. Z., Kumar, S., Chong, S. & Saif, Z., Jun 2017, In : Placenta. 54, p. 24-29 6 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)
2016

Creb1 regulates late stage mammalian lung development via respiratory epithelial and mesenchymal-independent mechanisms

Antony, N., McDougall, A. R., Mantamadiotis, T., Cole, T. J. & Bird, A. D., 6 May 2016, In : Scientific Reports. 6, 12 p., 25569.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)
2015

Aldosterone-mediated renal sodium transport requires intact mineralocorticoid receptor DNA binding in the mouse

Cole, T. J., Terella, L. R., Morgan, J., Alexiadis, M., Yao, Y-Z., Enriori, P., Young, M. J. & Fuller, P. J., 2015, In : Endocrinology. 156, 8, p. 2958 - 2968 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Expression of eight glucocorticoid receptor isoforms in the human preterm placenta vary with fetal sex and birthweight

Saif, Z., Hodyl, N. A., Stark, M. J., Fuller, P. J., Cole, T. J., Lu, N. Z. & Clifton, V. L., 2015, In : Placenta. 36, 7, p. 723 - 730 8 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)

Minireview: Glucocorticoid regulation of lung development: lessons learned from conditional GR knockout mice

Bird, A. D., McDougall, A. R. A., Seow, B., Hooper, S. B. & Cole, T. J., 2015, In : Molecular Endocrinology. 29, 2, p. 158 - 171 14 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Trop2: from development to disease

McDougall, A. R. A., Tolcos, M., Hooper, S. B., Cole, T. J. & Wallace, M. J., 2015, In : Developmental Dynamics. 244, 2, p. 99 - 109 11 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)
2014

Glucocorticoid-mediated repression of T-cell receptor signalling is impaired in glucocorticoid receptor exon 2-disrupted mice

Liddicoat, D., Purton, J. F., Cole, T. J. & Godfrey, D. I., 2014, In : Immunology and Cell Biology. 92, 2, p. 148 - 155 8 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)
21 Citations (Scopus)

The glucocorticoid receptor 1A3 promoter correlates with high sensitivity to glucocorticoid-induced apoptosis in human lymphocytes

Liddicoat, D. R., Kyparissoudis, K., Berzins, S. P., Cole, T. J. & Godfrey, D. I., 2014, In : Immunology and Cell Biology. 92, 10, p. 825 - 836 12 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Transient vascular and long-term alveolar deficits following a hyperoxic injury to neonatal mouse lung

Firsova, A., Cole, T. J. & Mollard, R. A., 2014, In : BMC Pulmonary Medicine. 14, 1 (Art. No.: 59), p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
3 Citations (Scopus)
2013

cAMP response element binding protein1 is essential for activation of steroyl co-enzyme a desaturase 1 (Scd1) in mouse lung type II epithelial cells

Antony, N., Weir, J. R., McDougall, A. R. A., Mantamadiotis, T., Meikle, P. J., Cole, T. J. & Bird, A. D., 2013, In : PLoS ONE. 8, 4 , 12 p., e59763.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

Genome-wide ENU mutagenesis in combination with high density SNP analysis and exome sequencing provides rapid identification of novel mouse models of developmental disease

Caruana, G., Farlie, P. G., Hart, A. H., Bagheri-Fam, S., Wallace, M. J., Dobbie, M. S., Gordon, C. T., Miller, K. A., Whittle, B., Abud, H. E., Arkell, R. M., Cole, T. J., Harley, V. R., Smyth, I. M. & Bertram, J. F., 2013, In : PLoS ONE. 8, 3, 14 p., e55429.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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12 Citations (Scopus)

Nfil3 is a glucocorticoid-regulated gene required for glucocorticoid-induced apoptosis in male murine T cells

Carey, K. T., Tan, K. H., Ng, J. H. P., Liddicoat, D., Godfrey, D. I. & Cole, T. J., 2013, In : Endocrinology. 154, 4, p. 1540 - 1552 13 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Trop2 regulates motility and lamellipodia formation in cultured fetal lung fibroblasts

McDougall, A. R. A., Hooper, S. B., Zahra, V. A., Cole, T. J., Lo, C. Y-W., Doran, T. & Wallace, M. J., 2013, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 305, 7, p. 508 - 521 14 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)
2011

cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development

Bird, A. D., Flecknoe, S. J., Tan, K. H., Olsson, P. F., Antony, N., Mantamadiotis, T., Mollard, R. A., Hooper, S. B. & Cole, T. J., 2011, In : PLoS ONE. 6, 3, p. 1 - 15 15 p., e17843.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
18 Citations (Scopus)

The oncogene Trop2 regulates fetal lung cell proliferation

McDougall, A., Hooper, S., Zahra, V., Sozo, F., Lo, C., Cole, T., Doran, T. & Wallace, M., 2011, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 301, 4, p. L478 - L489 12 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)
2010

Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis

Jurado, S., Smyth, I. M., van Denderen, B. JW., Tenis, N., Hammet, A., Hewitt, K., Ng, J-L., McNees, C. J., Kozlov, S. V., Oka, H., Kobayashi, M., Conlan, L. A., Cole, T. J., Yamamoto, K., Taniguchi, Y., Takeda, S., Lavin, M. F. & Heierhorst, J., 1 Oct 2010, In : PLoS Genetics. 6, 10, 13 p., e1001170.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
23 Citations (Scopus)

Glucocorticoids stimulate hepatic and renal catecholamine inactivation by direct rapid induction of the dopamine sulfotransferase Sult1d1

Wong, S., Tan, W. K., Carey, K. T., Fukushima, A., Tiganis, T. & Cole, T. J., 2010, In : Endocrinology. 151, p. 185 - 194 9 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Metabolic effects of low dose angiotensin converting enzyme inhibitor in dietary obesity in the rat

Velkoska, E., Warner, F. J., Cole, T. J., Smith, A. I. & Morris, M. J., 2010, In : Nutrition Metabolism and Cardiovascular Diseases. 20, p. 49 - 55 6 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

The glucocorticoid receptor is required for experimental adrenocorticotrophic hormone-induced hypertension in mice

Zhang, Y., Schyvens, C. G., Cole, T. J., McKenzie, K. US., Vickers, J. J. & Whitworth, J. A., 2010, In : Clinical and Experimental Pharmacology and Physiology. 37, 11, p. 1044 - 1048 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2009

Early biomarkers and potential mediators of ventilation-induced lung injury in very preterm lambs

Wallace, M. J., Probyn, M. E., Zahra, V. A., Crossley, K. J., Cole, T. J., Davis, P. G., Morley, C. J. & Hooper, S. B., 2009, In : Respiratory Research. 10, 19, p. 1 - 15 15 p.

Research output: Contribution to journalArticleResearchpeer-review

80 Citations (Scopus)
2008

Early undernutrition leads to long-lasting reductions in body weight and adiposity whereas increased intake increases cardiac fibrosis in male rats

Velkoska, E., Cole, T. J., Dean, R. G., Burrell, L. M. & Morris, M. J., 2008, In : Journal of Nutrition. 138, 9, p. 1622 - 1627 6 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

Glucocorticoids antagonize estrogens by glucocorticoid receptor-mediated activation of estrogen sulfotransferase

Gong, H., Jarzynka, M. J., Cole, T. J., Lee, J. H., Wada, T., Zhang, B., Gao, J., Song, W-C., DeFranco, D., Cheng, S-Y. & Xie, W., 2008, In : Cancer Research. 68, 18, p. 7386 - 7393 8 p.

Research output: Contribution to journalArticleResearchpeer-review

100 Citations (Scopus)
2007

A direct effect of aldosterone on endothelin-1 gene expression in vivo

Wong, S., Brennan, F. E., Young, M. J., Fuller, P. J. & Cole, T. J., 2007, In : Endocrinology. 148, 4, p. 1511 - 1517 7 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

A murine respiratory-inducing niche displays variable efficiency across human and mouse embryonic stem cell species

Denham, M., Conley, B. J., Olsson, F. P., Gulluyan, L., Cole, T. J. & Mollard, R. A., 2007, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 292, 5, p. 1241 - 1247 7 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Deriving respiratory cell types from stem cells

Olsson, F. P., Denham, M., Cole, T. J., Hooper, S. B. & Mollard, R. A., 2007, In : Current Stem Cell Research and Therapy. 2, 3, p. 197 - 208 12 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Gender dictates the nuclear receptor-mediated regulation of CYP3A44

Anakk, S., Huang, W., Staudinger, J. L., Tan, K. H., Cole, T. J., Moore, D. & Strobel, H. W., 2007, In : Drug Metabolism and Disposition. 35, p. 36 - 42 6 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Identification of glucocorticoid-regulated genes that control cell proliferation during murine respiratory development

Bird, A. D., Tan, K. H., Olsson, F. P., Zieba, M., Flecknoe, S. J., Liddicoat, D., Mollard, R. A., Hooper, S. B. & Cole, T. J., 2007, In : The Journal of Physiology. 585, 1, p. 187 - 201 15 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

Selective glucocorticoid receptor ligands

Cole, T. J. & Mollard, R. A., 2007, In : Medicinal Chemistry. 3, 5, p. 494 - 506 13 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)
2006

Embryonic stem cells form glandular structures and express surfactant protein C following culture with dissociated fetal respiratory tissue

Denham, M. S., Cole, T. J. & Mollard, R. A., 2006, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 290, 6, p. L1210 - L1215 6 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)
2005

Central and peripheral contributions to obesity-associated hypertension: impact of early overnourishment

Morris, M. J., Velkoska, E. & Cole, T. J., 2005, In : Experimental Physiology. 90, 5, p. 697 - 702 6 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

Early dietary intervention: long-term effects on blood pressure, brain neuropeptide Y, and adiposity markers

Velkoska, E., Cole, T. J. & Morris, M. J., 2005, In : American Journal of Physiology - Endocrinology and Metabolism. 288, 6, p. E1236 - E1243 8 p.

Research output: Contribution to journalArticleResearchpeer-review

109 Citations (Scopus)

Evaluation of three biochemical markers in the monitoring of Gaucher disease

Vellodi, A., Foo, Y. & Cole, T. J., Aug 2005, In : Journal of Inherited Metabolic Disease. 28, 4, p. 585-592 8 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Intrathymic glucocorticoid production and thymocyte survival: another piece in the puzzle

Cole, T. J., Liddicoat, D. R. & Godfrey, D. I., 2005, In : Endocrinology. 146, 6, p. 2499 - 2500 2 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Mouse embryonic stem cell derivation, and mouse and human embryonic stem cell culture and differentiation as embryoid bodies

Conley, B. J., Denham, M., Gulluyan, L., Olsson, F. P., Cole, T. J. & Mollard, R. A., 2005, In : Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.]. Suppl 28, 23.2, p. 1 - 22 22 p.

Research output: Contribution to journalArticleOther

14 Citations (Scopus)

Stem cells: an overview.

Denham, M., Conley, B. J., Olsson, F. P., Cole, T. J. & Mollard, R. A., 2005, In : Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.]. Suppl 28, 23.1

Research output: Contribution to journalArticleOther

6 Citations (Scopus)
2004

Altered epithelial cell proportions in the fetal lung of glucocorticoid receptor null mice

Cole, T. J., Solomon, N. M., van Driel, R., Monk, J. A., Bird, D., Richardson, S. J., Dilley, R. J. & Hooper, S. B., 2004, In : American Journal of Respiratory Cell and Molecular Biology. 30, 5, p. 613 - 619 7 p.

Research output: Contribution to journalArticleResearchpeer-review

64 Citations (Scopus)

Circulating aldosterone levels are unexpectedly low in children with acute meningococcal disease

Lichtakowicz-Krynska, E. J., Cole, T. J., Camacho-Hubner, C., Britto, J., Levin, M., Klein, N. & Aynsley-Green, A., Mar 2004, In : The Journal of Clinical Endocrinology and Metabolism. 89, 3, p. 1410-1414 5 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Expression of the glucocorticoid receptor from the 1A promoter correlates with T lymphocyte sensitivity to glucocorticoid-induced cell death

Purton, J. F., Monk, J. A., Liddicoat, D. R., Kyparissoudis, K., Sakkal, S., Richardson, S. J., Godfrey, D. I. & Cole, T. J., 2004, In : Journal of Immunology. 173, 6, p. 3816 - 3824 9 p.

Research output: Contribution to journalArticleResearchpeer-review

58 Citations (Scopus)

Matrix metalloproteinase-9 genotype influences large artery stiffness through effects on aortic gene and protein expression

Medley, T. L., Cole, T. J., Dart, A. M., Gatzka, C. D. & Kingwell, B. A., 2004, In : Arteriosclerosis, Thrombosis and Vascular Biology. 24, 8, p. 1479 - 1484 6 p.

Research output: Contribution to journalArticleResearchpeer-review

113 Citations (Scopus)

TCR-mediated activation promotes GITR upregulation in T cells and resistance to glucocorticoid-induced death

Zhan, Y., Funda, D. P., Every, A. L., Fundova, P., Purton, J. F., Liddicoat, D., Cole, T. J., Godfrey, D. I., Brady, J. L., Mannering, S. I., Harrison, L. C. & Lew, A. M., 2004, In : International Immunology. 16, 9, p. 1315 - 1321 7 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)
2003

Matrix metalloproteinase-3 genotype contributes to age-related aortic stiffening through modulation of gene and protein expression

Medley, T. L., Kingwell, B. A., Gatzka, C. D., Pillay, P. & Cole, T. J., 2003, In : Circulation Research. 92, 11, p. 1254 - 1261 8 p.

Research output: Contribution to journalArticleResearchpeer-review

131 Citations (Scopus)