Thomas Davis

Professor

1984 …2021
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Research Output 1984 2019

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2019

Amphiphilic surface chemistry of fullerenols is necessary for inhibiting the amyloid aggregation of alpha-synuclein NACore

Sun, Y., Kakinen, A., Zhang, C., Yang, Y., Faridi, A., Davis, T. P., Cao, W., Ke, P. C. & Ding, F., 28 Jun 2019, In : Nanoscale. 11, 24, p. 11933-11945 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Amyloid Self-Assembly of hIAPP8-20 via the Accumulation of Helical Oligomers, α-Helix to β-Sheet Transition, and Formation of β-Barrel Intermediates

Sun, Y., Kakinen, A., Xing, Y., Faridi, P., Nandakumar, A., Purcell, A. W., Davis, T. P., Ke, P. C. & Ding, F., May 2019, In : Small. 15, 18, 10 p., 1805166.

Research output: Contribution to journalArticleResearchpeer-review

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

Somers, K., Wen, V. W., Middlemiss, S. M. C., Osborne, B., Forgham, H., Jung, M. S., Karsa, M., Clifton, M., Bongers, A., Gao, J., Mayoh, C., Raoufi-Rad, N., Kusnadi, E. P., Hannan, K. M., Scott, D. A., Kwek, A., Liu, B., Flemming, C., Chudakova, D. A., Pandher, R. & 17 othersFailes, T. W., Lim, J., Angeli, A., Osterman, A. L., Imamura, T., Kees, U. R., Supuran, C. T., Pearson, R. B., Hannan, R. D., Davis, T. P., McCarroll, J., Kavallaris, M., Turner, N., Gudkov, A. V., Haber, M., Norris, M. D. & Henderson, M. J., 22 Jan 2019, In : Oncogene. 38, 20, p. 3824-3842 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Controlling Nanomaterial Size and Shape for Biomedical Applications via Polymerization-Induced Self-Assembly

Khor, S. Y., Quinn, J. F., Whittaker, M. R., Truong, N. P. & Davis, T. P., Jan 2019, In : Macromolecular Rapid Communications. 40, 2, 22 p., 1800438.

Research output: Contribution to journalArticleResearchpeer-review

Development of a shape-controlled H 2 S delivery system using epoxide-functional nanoparticles

Yu, S. H., Esser, L., Khor, S. Y., Senyschyn, D., Veldhuis, N. A., Whittaker, M. R., Ercole, F., Davis, T. P. & Quinn, J. F., 23 Apr 2019, (Accepted/In press) In : Journal of Polymer Science, Part A: Polymer Chemistry. 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Functional Brush Poly(2-ethyl-2-oxazine)s: Synthesis by CROP and RAFT, Thermoresponsiveness and Grafting onto Iron Oxide Nanoparticles

Klein, T., Parkin, J., de Jongh, P. A. J. M., Esser, L., Sepehrizadeh, T., Zheng, G., De Veer, M., Alt, K., Hagemeyer, C. E., Haddleton, D. M., Davis, T. P., Thelakkat, M. & Kempe, K., May 2019, In : Macromolecular Rapid Communications. 40, 10, 6 p., 1800911.

Research output: Contribution to journalArticleResearchpeer-review

Functional Liquid Metal Nanoparticles Produced by Liquid-Based Nebulization

Tang, S. Y., Qiao, R., Lin, Y., Li, Y., Zhao, Q., Yuan, D., Yun, G., Guo, J., Dickey, M. D., Huang, T. J., Davis, T. P., Kalantar-Zadeh, K. & Li, W., Feb 2019, In : Advanced Materials Technologies. 4, 2, 9 p., 1800420.

Research output: Contribution to journalArticleResearchpeer-review

Nucleation of β-rich oligomers and β-barrels in the early aggregation of human islet amyloid polypeptide

Sun, Y., Kakinen, A., Xing, Y., Pilkington, E. H., Davis, T. P., Ke, P. C. & Ding, F., 1 Feb 2019, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1865, 2, p. 434-444 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Physical and toxicological profiles of human IAPP amyloids and plaques

Kakinen, A., Sun, Y., Javed, I., Faridi, A., Pilkington, E. H., Faridi, P., Purcell, A. W., Zhou, R., Ding, F., Lin, S., Ke, P. C. & Davis, T. P., 15 Jan 2019, In : Science Bulletin. 64, 1, p. 26-35 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Probing the Aggregation and Immune Response of Human Islet Amyloid Polypeptides with Ligand-Stabilized Gold Nanoparticles

Javed, I., He, J., Kakinen, A., Faridi, A., Yang, W., Davis, T. P., Ke, P. C. & Chen, P., 20 Mar 2019, In : ACS Applied Materials and Interfaces. 11, 11, 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis and identification of novel pryidazinylpyrazolone based diazo compounds as inhibitors of human islet amyloid polypeptide aggregation

Bin Farrukh, S. U., Javed, I., Ather, A. Q., Emwas, A-H., Alazmi, M., Gao, X., Chotana, G. A., Davis, T. P., Ke, P. C. & Saleem, R. S. Z., Mar 2019, In : Bioorganic Chemistry. 84, p. 339-346 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Tuning the Structure, Stability, and Responsivity of Polymeric Arsenical Nanoparticles Using Polythiol Cross-Linkers

Tanaka, J., Moriceau, G., Cook, A., Kerr, A., Zhang, J., Peltier, R., Perrier, S., Davis, T. P. & Wilson, P., 12 Feb 2019, In : Macromolecules. 52, 3, p. 992-1003 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

Arginine-Rich Manganese Silicate Nanobubbles as a Ferroptosis-Inducing Agent for Tumor-Targeted Theranostics

Wang, S., Li, F., Qiao, R., Hu, X., Liao, H., Chen, L., Wu, J., Wu, H., Zhao, M., Liu, J., Chen, R., Ma, X., Kim, D., Sun, J., Davis, T. P., Chen, C., Tian, J., Hyeon, T. & Ling, D., 26 Dec 2018, In : ACS Nano. 12, 12, p. 12380-12392 13 p.

Research output: Contribution to journalArticleResearchpeer-review

A tunable one-pot three-component synthesis of an 125I and Gd-labelled star polymer nanoparticle for hybrid imaging with MRI and nuclear medicine

Esser, L., Lengkeek, N. A., Moffat, B. A., Vu, M. N., Greguric, I., Quinn, J. F., Davis, T. P. & Whittaker, M. R., 7 Jul 2018, In : Polymer Chemistry. 9, 25, p. 3528-3535 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Bioconjugation and Fluorescence Labeling of Iron Oxide Nanoparticles Grafted with Bromomaleimide-Terminal Polymers

Qiao, R., Esser, L., Fu, C., Zhang, C., Hu, J., Ramírez-arcía, P., Li, Y., Quinn, J. F., Whittaker, M. R., Whittaker, A. K. & Davis, T. P., 12 Nov 2018, In : Biomacromolecules. 19, 11, p. 4423-4429 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Efficient Binding, Protection, and Self-Release of dsRNA in Soil by Linear and Star Cationic Polymers

Whitfield, R., Anastasaki, A., Truong, N. P., Cook, A. B., Omedes-Pujol, M., Loczenski Rose, V., Nguyen, T. A. H., Burns, J. A., Perrier, S., Davis, T. P. & Haddleton, D. M., 21 Aug 2018, In : ACS Macro Letters. 7, 8, p. 909-915 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Elucidating the Influences of Size, Surface Chemistry, and Dynamic Flow on Cellular Association of Nanoparticles Made by Polymerization-Induced Self-Assembly

Khor, S. Y., Vu, M. N., Pilkington, E. H., Johnston, A. P. R., Whittaker, M. R., Quinn, J. F., Truong, N. P. & Davis, T. P., 23 Aug 2018, In : Small. 14, 34, 13 p., 1801702.

Research output: Contribution to journalArticleResearchpeer-review

Exploiting macromolecular design to optimize the antibacterial activity of alkylated cationic oligomers

Grace, J. L., Schneider-Futschik, E. K., Elliott, A. G., Amado, M., Truong, N. P., Cooper, M. A., Li, J., Davis, T. P., Quinn, J. F., Velkov, T. & Whittaker, M. R., 10 Dec 2018, In : Biomacromolecules. 19, 12, p. 4629-4640 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Graphene quantum dots against human IAPP aggregation and toxicity in vivo

Wang, M., Sun, Y., Cao, X., Peng, G., Javed, I., Kakinen, A., Davis, T. P., Lin, S., Liu, J., Ding, F. & Ke, P. C., 14 Nov 2018, In : Nanoscale. 10, 42, p. 19995-20006 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Human plasma proteome association and cytotoxicity of nano-graphene oxide grafted with stealth polyethylene glycol and poly(2-ethyl-2-oxazoline)

Wang, M., Gustafsson, O. J. R., Siddiqui, G., Javed, I., Kelly, H. G., Blin, T., Yin, H., Kent, S. J., Creek, D. J., Kempe, K., Ke, P. C. & Davis, T. P., 21 Jun 2018, In : Nanoscale. 10, 23, p. 10863-10875 13 p.

Research output: Contribution to journalArticleResearchpeer-review

In Vivo Mitigation of Amyloidogenesis through Functional-Pathogenic Double-Protein Coronae

Javed, I., Yu, T., Peng, G., Sánchez-Ferrer, A., Faridi, A., Kakinen, A., Zhao, M., Mezzenga, R., Davis, T. P., Lin, S. & Ke, P. C., 12 Sep 2018, In : Nano Letters. 18, 9, p. 5797-5804 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Journey to the centre of the cell: Virtual reality immersion into scientific data

Johnston, A. P. R., Rae, J., Ariotti, N., Bailey, B., Lilja, A., Webb, R., Ferguson, C., Maher, S., Davis, T. P., Webb, R. I., McGhee, J. & Parton, R. G., 1 Feb 2018, In : Traffic. 19, 2, p. 105-110 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Linker chemistry dictates the delivery of a phototoxic organometallic rhenium(i) complex to human cervical cancer cells from core crosslinked star polymer nanoparticles

Yu, S. H., Patra, M., Ferrari, S., Ramirez Garcia, P., Veldhuis, N. A., Kaminskas, L. M., Graham, B., Quinn, J. F., Whittaker, M. R., Gasser, G. & Davis, T. P., 29 Oct 2018, In : Journal of Materials Chemistry B. 6, 47, p. 7805-7810 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Microfluidic Mass Production of Stabilized and Stealthy Liquid Metal Nanoparticles

Tang, S. Y., Qiao, R., Yan, S., Yuan, D., Zhao, Q., Yun, G., Davis, T. P. & Li, W., 24 May 2018, In : Small. 14, 21, 8 p., 1800118.

Research output: Contribution to journalArticleResearchpeer-review

Minimum information reporting in bio–nano experimental literature

Faria, M., Björnmalm, M., Thurecht, K. J., Kent, S. J., Parton, R. G., Kavallaris, M., Johnston, A. P. R., Gooding, J. J., Corrie, S. R., Boyd, B. J., Thordarson, P., Whittaker, A. K., Stevens, M. M., Prestidge, C. A., Porter, C. J. H., Parak, W. J., Davis, T. P., Crampin, E. J. & Caruso, F., 1 Sep 2018, In : Nature Nanotechnology. 13, 9, p. 777-785 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Mitigating Human IAPP Amyloidogenesis In Vivo with Chiral Silica Nanoribbons

Faridi, A., Sun, Y., Okazaki, Y., Peng, G., Gao, J., Kakinen, A., Faridi, P., Zhao, M., Javed, I., Purcell, A. W., Davis, T. P., Lin, S., Oda, R., Ding, F. & Ke, P. C., 22 Nov 2018, In : Small. 14, 47, 13 p., 1802825.

Research output: Contribution to journalArticleResearchpeer-review

Nano-assemblies of cationic mPEG brush block copolymers with gadolinium polyoxotungstate [Gd(W5O18)2]9- form stable, high relaxivity MRI contrast agents

Ly, J., Li, Y., Vu, M. N., Moffat, B. A., Jack, K. S., Quinn, J. F., Whittaker, M. R. & Davis, T. P., 21 Apr 2018, In : Nanoscale. 10, 15, p. 7270-7280 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Nanoscale inhibition of polymorphic and ambidextrous IAPP amyloid aggregation with small molecules

Kakinen, A., Adamcik, J., Wang, B., Ge, X., Mezzenga, R., Davis, T. P., Ding, F. & Ke, P. C., Jul 2018, In : Nano Research. 11, 7, p. 3636-3647 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Overcoming Surfactant-Induced Morphology Instability of Noncrosslinked Diblock Copolymer Nano-Objects Obtained by RAFT Emulsion Polymerization

Truong, N. P., Zhang, C., Nguyen, T. A. H., Anastasaki, A., Schulze, M. W., Quinn, J. F., Whittaker, A. K., Hawker, C. J., Whittaker, M. R. & Davis, T. P., 20 Feb 2018, In : ACS Macro Letters. 7, 2, p. 159-165 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Profiling the Serum Protein Corona of Fibrillar Human Islet Amyloid Polypeptide

Pilkington, E. H., Gustafsson, O. J. R., Xing, Y., Hernandez-Fernaud, J., Zampronio, C., Kakinen, A., Faridi, A., Ding, F., Wilson, P., Ke, P. C. & Davis, T. P., 26 Jun 2018, In : ACS Nano. 12, 6, p. 6066-6078 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Serum albumin impedes the amyloid aggregation and hemolysis of human islet amyloid polypeptide and alpha synuclein

Kakinen, A., Javed, I., Faridi, A., Davis, T. P. & Ke, P. C., Sep 2018, In : Biochimica et Biophysica Acta - Biomembranes. 1860, 9, p. 1803-1809 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis, aggregation and responsivity of block copolymers containing organic arsenicals

Tanaka, J., Tani, S., Peltier, R., Pilkington, E. H., Kerr, A., Davis, T. P. & Wilson, P., 7 Apr 2018, In : Polymer Chemistry. 9, 13, p. 1551-1556 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Understanding Effects of PAMAM Dendrimer Size and Surface Chemistry on Serum Protein Binding with Discrete Molecular Dynamics Simulations

Wang, B., Sun, Y., Davis, T. P., Ke, P. C., Wu, Y. & Ding, F., 4 Sep 2018, In : ACS Sustainable Chemistry & Engineering. 6, 9, p. 11704-11715 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Uptake and transcytosis of functionalized superparamagnetic iron oxide nanoparticles in an: In vitro blood brain barrier model

Ivask, A., Pilkington, E. H., Blin, T., Käkinen, A., Vija, H., Visnapuu, M., Quinn, J. F., Whittaker, M. R., Qiao, R., Davis, T. P., Ke, P. C. & Voelcker, N. H., 1 Feb 2018, In : Biomaterials Science. 6, 2, p. 314-323 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2017

A hydrogel-based localized release of colistin for antimicrobial treatment of burn wound infection

Zhu, C., Zhao, J., Kempe, K., Wilson, P., Wang, J., Velkov, T., Li, J., Davis, T. P., Whittaker, M. R. & Haddleton, D. M., 2017, In : Macromolecular Bioscience. 17, 2, 7 p., 1600320.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

A traceless reversible polymeric colistin prodrug to combat multidrug-resistant (MDR) gram-negative bacteria

Zhu, C., Schneider, E. K., Wang, J., Kempe, K., Wilson, P., Velkov, T., Li, J., Davis, T., Whittaker, M. R. & Haddleton, D. M., 2017, In : Journal of Controlled Release. 259, 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Cationic acrylate oligomers comprising amino acid mimic moieties demonstrate improved antibacterial killing efficiency

Grace, J., Elliott, A. G., Huang, J. X., Schneider, E. K., Truong Phuoc, N., Cooper, M. A., Li, J., Davis, T., Quinn, J., Velkov, T. & Whittaker, M. R., 2017, In : Journal of Materials Chemistry B. 5, 3, p. 531-536 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Cofibrillization of Pathogenic and Functional Amyloid Proteins with Gold Nanoparticles against Amyloidogenesis

Javed, I., Sun, Y., Adamcik, J., Wang, B., Kakinen, A., Pilkington, E. H., Ding, F., Mezzenga, R., Davis, T. P. & Ke, P. C., 11 Dec 2017, In : Biomacromolecules. 18, 12, p. 4316-4322 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Comb poly(oligo(2-ethyl-2-oxazoline)methacrylate)-peptide conjugates prepared by aqueous Cu(0)-mediated polymerization and reductive amination

Collins, J., Wallis, S. J., Simula, A., Whittaker, M. R., McIntosh, M. P., Wilson, P., Davis, T. P., Haddleton, D. M. & Kempe, K., 1 Jan 2017, In : Macromolecular Rapid Communications. 38, 2, 7 p., 1600534.

Research output: Contribution to journalArticleResearchpeer-review

Copolyampholytes Produced from RAFT Polymerization of Protic Ionic Liquids

Fouillet, C. C. J., Greaves, T. L., Quinn, J. F., Davis, T. P., Adamcik, J., Sani, M. A., Separovic, F., Drummond, C. J. & Mezzenga, R., 28 Nov 2017, In : Macromolecules. 50, 22, p. 8965-8978 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Differential effects of silver and iron oxide nanoparticles on IAPP amyloid aggregation

Wang, M., Kakinen, A., Pilkington, E. H., Davis, T. P. & Ke, P-C., 1 Mar 2017, In : Biomaterials Science. 5, 3, p. 485-493 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Effects of protein corona on IAPP amyloid aggregation, fibril remodelling, and cytotoxicity

Pilkington, E. H., Xing, Y., Wang, B., Kakinen, A., Wang, M., Davis, T. P., Ding, F. & Ke, P-C., 1 Dec 2017, In : Scientific Reports. 7, 1, 13 p., 2455.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Engineered hydrogen-bonded glycopolymer capsules and their interactions with antigen presenting cells

Kempe, K., Xiang, S. D., Wilson, P., Rahim, M. A., Ju, Y., Whittaker, M. R., Haddleton, D. M., Plebanski, M., Caruso, F. & Davis, T. P., 22 Feb 2017, In : ACS Applied Materials and Interfaces. 9, 7, p. 6444-6452 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Garlic-inspired trisulfide linkers for thiol-stimulated H2S release

Ercole, F., Whittaker, M. R., Halls, M. L., Boyd, B. J., Davis, T. P. & Quinn, J. F., 2017, In : Chemical Communications. 53, 57, p. 8030-8033 4 p.

Research output: Contribution to journalArticleResearchpeer-review

File

Hydrolyzable Poly[Poly(Ethylene Glycol) Methyl Ether Acrylate]-Colistin Prodrugs through Copper-Mediated Photoinduced Living Radical Polymerization

Zhu, C., Schneider, E. K., Nikolaou, V., Klein, T., Li, J., Davis, T. P., Whittaker, M. R., Wilson, P., Kempe, K., Velkov, T. & Haddleton, D. M., 19 Jul 2017, In : Bioconjugate Chemistry. 28, 7, p. 1916-1924 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Influence of Size and Shape on the Biodistribution of Nanoparticles Prepared by Polymerization-Induced Self-Assembly

Kaga, S., Truong, N. P., Esser, L., Senyschyn, D., Sanyal, A., Sanyal, R., Quinn, J. F., Davis, T. P., Kaminskas, L. M. & Whittaker, M. R., 11 Dec 2017, In : Biomacromolecules. 18, 12, p. 3963-3970 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Light-Mediated Atom Transfer Radical Polymerization of Semi-Fluorinated (Meth)acrylates: Facile Access to Functional Materials

Discekici, E. H., Anastasaki, A., Kaminker, R., Willenbacher, J., Truong, N. P., Fleischmann, C., Oschmann, B., Lunn, D. J., Read De Alaniz, J., Davis, T. P., Bates, C. M. & Hawker, C. J., 26 Apr 2017, In : Journal of the American Chemical Society. 139, 16, p. 5939-5945 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Lipidated polymers for the stabilization of cubosomes: Nanostructured drug delivery vehicles

Grace, J. L., Alcaraz, N., Truong, N. P., Davis, T. P., Boyd, B. J., Quinn, J. F. & Whittaker, M. R., 2017, In : Chemical Communications. 53, 76, p. 10552-10555 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Lysophosphatidylcholine modulates the aggregation of human islet amyloid polypeptide

Xing, Y., Pilkington, E. H., Wang, M., Nowell, C. J., Kakinen, A., Sun, Y., Wang, B., Davis, T. P., Ding, F. & Ke, P. C., 7 Dec 2017, In : Physical Chemistry Chemical Physics. 19, 45, p. 30627-30635 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Modular photo-induced RAFT polymerised hydrogels: Via thiol-ene click chemistry for 3D cell culturing

Tan, V. T. G., Nguyen, D. H. T., Utama, R. H., Kahram, M., Ercole, F., Quinn, J. F., Whittaker, M. R., Davis, T. P. & Justin Gooding, J., 21 Oct 2017, In : Polymer Chemistry. 8, 39, p. 6123-6133 11 p.

Research output: Contribution to journalArticleResearchpeer-review