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PhD projects

Email: thet.thet.htar@monash.edu Project Title: Development of a new receptor-targeted fluorescent probe and its mechanistic study as a potential for breast cancer imaging This study focuses on the design, synthesis of new estrogen receptor-targeted fluorescent probes. The study involves profiling of the synthesized probes regarding their selectivity among estrogen receptor subtypes, binding affinity as a potential probe for imaging breast cancer cells.

20142022

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Personal profile

Biography

Dr Thet graduated with a Bachelor of Pharmacy (Honours) in 1999 from the University of Wales in Cardiff, United Kingdom. She completed her pre-registration training at West Wales General Hospital in Carmarthen, Wales. She became a registered pharmacist and a member of the Royal Pharmaceutical Society of Great Britain (RPSGB) in 2000.

Dr Thet then went on to pursue her doctorate in Medicinal Chemistry at the University of Wales in Cardiff and completed it in early 2004.  As part of her continuing professional development, Dr Thet also served as a community pharmacist on a sessional basis in several pharmacies in the United Kingdom from 2000 – 2003.

Dr Thet was appointed an academic lecturer in medicinal chemistry at the School of Pharmacy, Faculty of Medical Sciences, UCSI University, Malaysia in 2004. In 2009, Dr Thet joined Monash University, Malaysia as an academic researcher. 

Research interests

Dr Thet's research interest area includes small molecule synthesis, molecular docking and simulation studies and molecular imaging. Currently, her research areas are bridged between the multidisciplinary research areas that focus on breast cancer research.

Supervision interests

Dr Thet has supervised seven PhD students and one Master student since 2017. Under her supervision, two PhD students and one Master student have successfully completed. 

Monash teaching commitment

Dr Thet teaches undergraduate pharmacy students in their course units where involving medicinal chemistry, physical and organic chemistry. 

Consulting

Dr Thet is happy to provide consultation in research areas within her expertise. 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Medicinal Chemistry, PhD, Cardiff University

Award Date: 14 Jun 2004

Pharmacy, BPharm (Hons), Cardiff University

Award Date: 14 Jun 1999

Research area keywords

  • Medicinal Chemistry
  • Organic Synthesis
  • Natural Products
  • Drug design in antiviral and anticancer agents
  • molecular dynamics
  • GPER
  • Estrogen receptors
  • Breast cancer
  • Curcumin

Network

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