Projects per year
Personal profile
Biography
Dr Thet graduated with a Bachelor of Pharmacy (Honours) in 1999 from the University of Wales in Cardiff, United Kingdom. She completed her pre-registration training at West Wales General Hospital in Carmarthen, Wales. She became a registered pharmacist and a member of the Royal Pharmaceutical Society of Great Britain (RPSGB) in 2000.
Dr Thet then went on to pursue her doctorate in Medicinal Chemistry at the University of Wales in Cardiff and completed it in early 2004. As part of her continuing professional development, Dr Thet also served as a community pharmacist on a sessional basis in several pharmacies in the United Kingdom from 2000 – 2003.
Dr Thet was appointed an academic lecturer in medicinal chemistry at the School of Pharmacy, Faculty of Medical Sciences, UCSI University, Malaysia in 2004. In 2009, Dr Thet joined Monash University, Malaysia as an academic researcher.
Research interests
Dr Thet's research interest area includes small molecule synthesis, molecular docking and simulation studies and molecular imaging. Currently, her research areas are bridged between the multidisciplinary research areas that focus on breast cancer research.
Supervision interests
Dr Thet has supervised seven PhD students and one Master student since 2017. Under her supervision, two PhD students and one Master student have successfully completed.
Monash teaching commitment
Dr Thet teaches undergraduate pharmacy students in their course units where involving medicinal chemistry, physical and organic chemistry.
Consulting
Dr Thet is happy to provide consultation in research areas within her expertise.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicinal Chemistry, PhD, Design and synthesis of conformationally restrained bicyclic nucleosides as potential antiviral agents, Cardiff University
Award Date: 14 Jun 2004
Pharmacy, BPharm (Hons), Design and synthesis of a novel nucleoside as a potential anti-HIV agent, Cardiff University
Award Date: 14 Jun 1999
Research area keywords
- Medicinal Chemistry
- Organic Synthesis
- Natural Products
- Drug design in antiviral and anticancer agents
- molecular dynamics
- GPER
- Estrogen receptors
- Breast cancer
- Curcumin
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A prospective, double-blinded, vehicle- controlled, randomized controlled trial to evaluate the efficacy of a formulated dressing membrane containing Tocotrienols skin lesion wound care
Chuah, A. (Primary Chief Investigator (PCI)), Siew Hua, G. (Chief Investigator (CI)), Htar, T. T. (Chief Investigator (CI)), Teoh, L. Y. (Chief Investigator (CI)) & Ju Yen, F. (Chief Investigator (CI))
23/05/22 → 30/06/27
Project: Research
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Mechanistic studies to understand enzyme inhibition: Towards the development of new anti-HIV agents based on quinoline scaffold
Ahemad, N. (Primary Chief Investigator (PCI)), SyedHassan, S. (Chief Investigator (CI)), Ali Shah, S. A. (Chief Investigator (CI)), Kim San, T. (Chief Investigator (CI)), Htar, T. T. (Chief Investigator (CI)) & Ahmad, M. N. (Chief Investigator (CI))
1/11/20 → 30/04/23
Project: Research
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Development of a new receptor-targeted fluorescent probe and its mechanistic study as a potential for breast cancer imaging
Htar, T. T. (Primary Chief Investigator (PCI)), Chow, S. C. (Chief Investigator (CI)), Naidu, R. (Chief Investigator (CI)), Ahemad, N. (Chief Investigator (CI)), Chuah, A. (Chief Investigator (CI)) & Yeong, K. Y. (Chief Investigator (CI))
1/11/20 → 31/10/24
Project: Research
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Use of guided active learning in thermodynamics to improve the performance of pharmacy students
1/01/16 → 30/06/16
Project: Research
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Identification of the pharmacophoric groups of an ideal GPER-1 ligand and its interaction mechanism with the receptor in breast cancer cells
Htar, T. T. (Primary Chief Investigator (PCI)), Naidu, R. (Chief Investigator (CI)), Ahemad, N. (Chief Investigator (CI)) & Chuah, A. (Chief Investigator (CI))
2/11/15 → 1/11/18
Project: Research
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Pharmacophore-based virtual screening, molecular docking and molecular dynamics studies for the discovery of novel neuraminidase inhibitors
Lotfi, B., Mebarka, O., Khan, S. U. & Htar, T. T., 2024, In: Journal of Biomolecular Structure and Dynamics. 42, 10, p. 5308-5320 13 p.Research output: Contribution to journal › Article › Research › peer-review
9 Citations (Scopus) -
Thiadiazine thione derivatives as anti-leishmanial agents: synthesis, biological evaluation, structure activity relationship, ADMET, molecular docking and molecular dyanamics simulation studies
Tamanna, Fu, C., Qadir, M., Shah, M. I. A., Shtaiwi, A., Khan, R., Khan, S. U., Htar, T. T., Zada, A., Lodhi, M. A., Ateeq, M., Ali, A., Naeem, M., Ibrahim, M. & Khan, S. W., 2024, In: Journal of Biomolecular Structure and Dynamics. 42, 15, 15 p.Research output: Contribution to journal › Article › Research › peer-review
6 Citations (Scopus) -
Unveiling the power of phytochemicals: Virtual screening of phytochemicals
Khan, S. U., Khan, N. H., Nahar, L., Sarker, S. D., Rehman, F.-U. & Htar, T. T., 8 Mar 2024, Computational Phytochemistry. Sarker, S. D. & Nahar, L. (eds.). 2nd ed. Amsterdam, Netherlands: Elsevier, p. 413-437 25 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Research › peer-review
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Computer-aided drug designing illuminate polypharmacology of natural products against multiple estrogen receptor
Khan, S. U., Khan, A. U., Kamal, M. A. & Htar, T. T., 2023, Computational Approaches in Drug Discovery, Development and Systems Pharmacology. Gautam, R. K., Kamal, M. A. & Mittal, P. (eds.). 1st ed. London UK: Academic Press, p. 281-333 53 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Research › peer-review
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Editorial: Recent advances in small molecule-based targeted therapy for breast cancer
Htar, T. T., Naidu, R., Lim, V. & Pandey, A. K., 18 Dec 2023, In: Frontiers in Pharmacology. 14, 2 p., 1343664.Research output: Contribution to journal › Editorial › Other › peer-review
Open AccessFile2 Citations (Scopus)