Projects per year
- 1 - 50 out of 92 results
Search results
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Finished
NHMRC Equipment Grant - Lateral Fluid Percussion Injury (LFPI) Device
Vivash, L., Leung, J., Casillas-Espinosa, P., Ali, I., O'Brien, T., Shultz, S. & Jones, N.
1/11/23 → 31/12/24
Project: Research
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REVEAL – Research Evaluating Vagal Excitation and Anatomical Linkages (Clinical Core)
Osborn, J. W., Macefield, V. & O'Brien, T.
1/09/23 → 31/08/24
Project: Research
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Drug screening using Homer1 patient’s iPSCs-derived neurons for clinical trials of precision medicine
Javaid, S., Rollo, B., Antonic-Baker, A., Kwan, P. & O'Brien, T.
17/04/23 → 30/09/24
Project: Research
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RENAISSANCE Study: A Phase 2, Multicenter, Open Label Safety and Tolerability Study of SPN-817 in Adult Patients with Treatment Resistant Epilepsy
O'Brien, T., Nicolo, J., Perucca, P., Reutens, D. C., Carney, P., Somerville, E. R., Wijayath, M. & Wong, T.
19/12/22 → 18/12/24
Project: Research
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Human high-throughput in-vitro phenotypic screening for new epilepsy drugs
Rollo, B., Kwan, P., O'Brien, T., Langmead, C., Baell, J., Casillas-Espinosa, P., May, L., Ayers, K. L. & Sumer, H.
1/06/22 → 1/01/23
Project: Research
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Translational platform for epilepsy therapy and biomarker discovery
Galanopoulou, A. S., Moshe, S., Mowrey, W. B., Branch, C., Fleysher, R., Cui , M., Staba, R. J., Mazarati, A., Sankar, R., Agoston, D., Duncan, D., Cabeen, R., Coles, L., O'Brien, T., Toga, A. W., Bragin, A., Engel, J., Vespa, P., Harris, N., Wright, D., Jones, N., Shultz, S., Casillas-Espinosa, P., Hudson, M., Ali, I. & Braine, E.
NIH - National Institutes of Health (United States of America)
15/04/22 → 31/03/23
Project: Research
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The contribution of monocytes and P2X7 Receptor in Multiple Sclerosis relapse.
Monif, M., Butzkueven, H., O'Brien, T. & Stankovich, J.
2/02/22 → 31/12/23
Project: Research
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HIT-IQ kinematics and observation of head impacts in Australian football
Mitra, B., McDonald, S., Willmott, C., Shultz, S., Makdissi, M. & O'Brien, T.
1/01/22 → 31/12/23
Project: Research
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Brain injury in intimate partner violence: Insight into a silent pandemic
Shultz, S., O'Sullivan, M. J., Fitz-Gibbon, K., Meyer, S., van Donkelaar, P., Christie, B. R., Mychasiuk, R., McDonald, S., Law, M., Vivash, L., O'Brien, T., Ponsford, J., Jupp, B., Chen, Z., Mitra, B. & Marks, J.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/22 → 31/12/24
Project: Research
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3D printer - Stratasys Objet30 Pro:
Kwan, P., O'Brien, T., Jones, N., Casillas-Espinosa, P., Hudson, M., Wright, D., Alan, T., French, C., Chan, J. & Jayawardena, A.
1/10/21 → 31/12/22
Project: Research
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Measuring inflammation in brain and blood for predicting risk of post-traumatic epilepsy
Ali, I., Jones, N., O'Brien, T., Dedeurwaerdere, S., Wright, D. & Vivash, L.
United States Department of Defense (DOD)
30/09/21 → 29/06/24
Project: Research
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Testing of Epidarex Exeed compounds for anti-epileptiform activity in a human neural in vitro assay
Rollo, B., O'Brien, T., Kwan, P. & Javaid, S.
1/09/21 → 1/03/22
Project: Research
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An Open-Label Ascending Single-Dose, and Randomized, Double-blind, Placebo-controlled, Ascending Multiple-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CST-2032 in Healthy Volunteers and Subjects with Mild Cognitive Impairment or Parkinson's Disease
O'Brien, T. & Kerris, J.
29/07/21 → 31/12/24
Project: Research
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An informatics approach to predict outcomes and monitor intervention efficacy following moderate to severe traumatic brain injury
Fitzgerald, M., Gabbe, B., Lannin, N., Vallmuur, K., Curtis, K., Harrison, J., Young, J. T., Menon, D. K., Cullen, J. C., Armstrong, E., Eades, S., Cameron, P., Cooper, J., Fitzgerald, M., Balogh, Z., Fatovich, D., Honeybul, S., Jeffree, R. L., McNamara, R., Mitchell, G. J., Delaney, A., Reade, M. C., Wells, A., Williams, J. K., Ponsford, J., McDonald, S., Kendall, E., Ownsworth , T., Simpson, G., Togher, L., Hassett, L., Fleming, J., Williams, G. P., Collins-Praino, L., Reeder, S., Mobbs, R., Vickers, J. C., Anderson, V., Barlow, K., Holland, A. J. A., Scheinberg, A., Semple, B., Parizel, P. M., O'Brien, T., Law, M., Rose, S. E., Varma, D., Nasrallah, F., Shultz, S., Hellewell, S. C., Bosio, E., King, K., Parr, M., Udy, A., Hill, A. F., Olver, J., Teague, W. J., Egan, G., Fisher, M., York, L., Bynevelt, M., Maas, A. I. R., O'Reilly, G., McDonald, S., Capell, J., Gilroy, J., Walsham, J., Newcombe, V., Geraghty, T. J., Joyce, C. J., Rosenfeld, J., Elcock, M., Ross, J., Bragge, P., Meka, S., Chai, K., Cowen, G., Hasseler, L., Ercole, A., Wagland , J., Alexander, T., Babl, F. E., Bidargaddi, N., Mahoney, A. J., Wright, D., Crowe, L. M., Robinson, S., Rushworth, N., Hansen, M., Ellis, D., Zeeman, H., Francis, R., Whiley, L. & Reid, C. M.
1/07/21 → 30/06/23
Project: Research
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Exercise therapy for mild traumatic brain injury (mTBI) and persistent post-concussion symptoms (PPCS) across the lifespan
O'Brien, T., Leddy, J., Willmott, C., Mitra, B., Shultz, S., Chen, Z., McDonald, S., Morokoff, A., Caeyenberghs, K., Ponsford, J., Rushworth, N., Akhlaghi, H., Davies, K. & Olver, J.
Department of Health and Aged Care (Australia)
1/06/21 → 31/05/24
Project: Research
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Transforming the paradigm of epilepsy care with precision medicine
Wolvetang, E. J., Kwan, P., Vadlamudi, L., O'Brien, T., Ge, Z., Anderson, A., Shaker, M., Antonic-Baker, A., Leeson, H., Rollo, B. & Javaid, S.
Department of Health and Aged Care (Australia)
1/06/21 → 31/05/24
Project: Research
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The contribution of monocytes and P2X7 Receptor in Multiple Sclerosis relapse.
Monif, M., Butzkueven, H., O'Brien, T. & Stankovich, J.
2/03/21 → 31/12/21
Project: Research
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Changzhou Trendi Medical Technology Co Ltd - Equipment Research Agreement
Changzhou Trendi Medical Technology Co Ltd
1/03/21 → 29/02/24
Project: Research
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Educational Grant - Monash Alfred 2021 Movement Disorders Fellowship
1/02/21 → 31/01/22
Project: Research
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A Phase 2A, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety and Pharmacokinetics of ES-481 in Adult Patients with Drug Resistant Epilepsy.
O'Brien, T., Mullen, S. A., Nicolo, J. & Reutens, D. C.
18/01/21 → 18/07/21
Project: Research
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Testing novel anti-epileptic compounds in human in vitro seizure model.
Rollo, B., O'Brien, T. & Kwan, P.
11/01/21 → 10/04/21
Project: Research
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Infections promote post-traumatic epilepsy and poor outcomes after traumatic brain injury
Semple, B., O'Brien, T. & Li, J.
United States Department of Defense (DOD)
4/01/21 → 29/09/24
Project: Research
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A 57-Week, Multicenter, Active-treatment, Open-label Extension Trial of CVL-865 as Adjunctive Therapy in Adults with Drug-Resistant Focal Onset Seizures.
O'Brien, T., Nicolo, J., Nikpour, A., Wijayath, M., D'Souza, W. J., Reutens, D. C., Carney, P., Somerville, E. R., Mullen, S. A. & Frasca, J.
18/12/20 → 31/12/24
Project: Research
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Improvement First Seizure Assessment and Management
O'Brien, T., Perucca, P., Liew, D., Ademi Delaney, Z. & Carney, P.
Monash University – Internal University Contribution, Epilepsy Foundation
1/12/20 → 31/12/22
Project: Research
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Testing of the effect of E2730 treatment on multimodality in-vivo biomarkers of GABAergic function in healthy rats and preclinical chronic epilepsy models
O'Brien, T., Kwan, P., Ali, I., Casillas-Espinosa, P., Jones, N., Jupp, B., Vivash, L., Wright, D., Mychasiuk, R. & Major, B.
Eisai Inc (United States of America)
22/10/20 → 21/10/21
Project: Research
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A Multicenter, Open-label Extension Study to Evaluate the Safety, Pharmacodynamics, and Clinical Effects of WVE-120102 in Patients with Huntington's Disease.
O'Brien, T. & Burn, K.
1/09/20 → 30/04/23
Project: Research
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A Multicenter, Open-label Extension Study to Evaluate the Safety, Pharmacodynamics, and Clinical Effects of WVE-120101 in Patients with Huntington's Disease.
O'Brien, T. & Burn, K.
1/09/20 → 30/04/23
Project: Research
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Evaluating Huperzine as an anti-seizure agent in the GAERS model of GGE with absence seizures.
Casillas-Espinosa, P. & O'Brien, T.
25/08/20 → 24/11/20
Project: Research
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MCIS: Characterising Mild Cognitive Impairment using multimodal biomarkers.
17/08/20 → 31/12/21
Project: Research
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A Phase 2, Double-Blind, Randomized, Placebo-Controlled Study to Assess Intracerebroventricular (ICV) Delivery of CT-010 via an Implantable Pump and a Cranial Port and Double Lumen Catheter (ICVRX) in Subjects with Focal Seizures, with Temporal Lobe Onset with or without Secondary Generalization
O'Brien, T. & Germaine, J.
17/06/20 → 31/12/24
Project: Research
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A randomized, double-blind, placebo-controlled, parallel group, multicenter trial of CVL-865 as adjunctive therapy in adults with drug-resistant focal onset seizures (REALIZE TRIAL)
O'Brien, T., Nicolo, J., Nikpour, A., Wijayath, M., D'Souza, W. J., Reutens, D. C., Carney, P., Somerville, E. R., Mullen, S. A. & Frasca, J.
5/06/20 → 31/12/23
Project: Research
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A Therapeutic Intervention, Open Label Study to Compare the Efficacy and Safety of Graded Exercise Compared to Passive Stretching in Subjects Who Have Sustained a Mild Traumatic Brain Injury
O'Brien, T., Barlow, K., Levi, C. R. & Jankelowitz, S.
5/05/20 → 31/12/23
Project: Research
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Seizure Detection Using Electrocardiogram Recordings and Kaoskey TRIO Software Study (KAOSKEY-K-001).
O'Brien, T. & Thomas, J.
1/05/20 → 31/12/21
Project: Research
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First Seizures: Patient Reported Outcome Measures
Ademi Delaney, Z., Foster, E., Kwan, P., Chen, Z., O'Brien, T., Liew, D. & Zomer, E.
30/04/20 → 30/03/24
Project: Research
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An Extension Study of ANAVEX2-73 in Patients with Mild to Moderate Alzheimer's Disease.
Darby, D., O'Brien, T. & Burn, K.
16/03/20 → 31/12/21
Project: Research
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UNCOVERING THE HIDDEN GENETICS OF NON-LESIONAL FOCAL EPILEPSY
Perucca, P., Berkovic, S. F., O'Brien, T., Kwan, P., Hildebrand, M. S., Scheffer, I. E. & McIntosh, A.
20/02/20 → 28/02/23
Project: Research
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Optimisation of first seizure management: a retrospective data linkage analysis
Foster, E., O'Brien, T., Kwan, P., Liew, D., Ademi Delaney, Z. & Chen, Z.
1/01/20 → 31/12/20
Project: Research