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  • 2020

    Genomewide association study of severe COVID-19 with respiratory failure

    Ellinghaus, D., Degenhardt, F., Bujanda, L., Buti, M., Albillos, A., Invernizzi, P., Fernández, J., Prati, D., Baselli, G., Asselta, R., Grimsrud, M. M., Milani, C., Aziz, F., Kässens, J., May, S., Wendorff, M., Wienbrandt, L., Uellendahl-Werth, F., Zheng, T., Yi, X. & 126 others, de Pablo, R., Chercoles, A. G., Palom, A., Garcia-Fernandez, A. E., Rodriguez-Frias, F., Zanella, A., Bandera, A., Protti, A., Aghemo, A., Lleo, A., Biondi, A., Caballero-Garralda, A., Gori, A., Tanck, A., Nolla, A. C., Latiano, A., Fracanzani, A. L., Peschuck, A., Julià, A., Pesenti, A., Voza, A., Jiménez, D., Mateos, B., Jimenez, B. N., Quereda, C., Paccapelo, C., Gassner, C., Angelini, C., Cea, C., Solier, A., Pestaña, D., Muñiz-Diaz, E., Sandoval, E., Paraboschi, E. M., Navas, E., Sánchez, F. G., Ceriotti, F., Martinelli-Boneschi, F., Peyvandi, F., Blasi, F., Téllez, L., Blanco-Grau, A., Hemmrich-Stanisak, G., Grasselli, G., Costantino, G., Cardamone, G., Foti, G., Aneli, S., Kurihara, H., ElAbd, H., My, I., Galván-Femenia, I., Martín, J., Erdmann, J., Ferrusquía-Acosta, J., Garcia-Etxebarria, K., Izquierdo-Sanchez, L., Bettini, L. R., Sumoy, L., Terranova, L., Moreira, L., Santoro, L., Scudeller, L., Mesonero, F., Roade, L., Rühlemann, M. C., Schaefer, M., Carrabba, M., Riveiro-Barciela, M., Basso, M. E. F., Valsecchi, M. G., Hernandez-Tejero, M., Acosta-Herrera, M., D'Angiò, M., Baldini, M., Cazzaniga, M., Schulzky, M., Cecconi, M., Wittig, M., Ciccarelli, M., Rodríguez-Gandía, M., Bocciolone, M., Miozzo, M., Montano, N., Braun, N., Sacchi, N., Martínez, N., Özer, O., Palmieri, O., Faverio, P., Preatoni, P., Bonfanti, P., Omodei, P., Tentorio, P., Castro, P., Rodrigues, P. M., Ortiz, A. B., de Cid, R., Ferrer, R., Gualtierotti, R., Nieto, R., Goerg, S., Badalamenti, S., Marsal, S., Matullo, G., Pelusi, S., Juzenas, S., Aliberti, S., Monzani, V., Moreno, V., Wesse, T., Lenz, T. L., Pumarola, T., Rimoldi, V., Bosari, S., Albrecht, W., Peter, W., Romero-Gómez, M., D'Amato, M., Duga, S., Banales, J. M., Hov, J. R., Folseraas, T., Valenti, L., Franke, A. & Karlsen, T. H., 15 Oct 2020, In: The New England Journal of Medicine. 383, 16, p. 1522-1534 13 p.

    Research output: Contribution to journalArticleResearchpeer-review

    Open Access
    376 Citations (Scopus)
  • Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome

    Mars, R. A. T., Yang, Y., Ward, T., Houtti, M., Priya, S., Lekatz, H. R., Tang, X., Sun, Z., Kalari, K. R., Korem, T., Bhattarai, Y., Zheng, T., Bar, N., Frost, G., Johnson, A. J., van Treuren, W., Han, S., Ordog, T., Grover, M., Sonnenburg, J. & 9 others, D'Amato, M., Camilleri, M., Elinav, E., Segal, E., Blekhman, R., Farrugia, G., Swann, J. R., Knights, D. & Kashyap, P. C., 17 Sep 2020, In: Cell. 182, 6, p. 1460-1473.e17 14 p.

    Research output: Contribution to journalArticleResearchpeer-review

    12 Citations (Scopus)
  • 2019

    Direct repression of anoctamin 1 (ANO1) gene transcription by Gli proteins

    Mazzone, A., Gibbons, S. J., Eisenman, S. T., Strege, P. R., Zheng, T., D'Amato, M., Ordog, T., Fernandez-Zapico, M. E. & Farrugia, G., 1 May 2019, In: The FASEB Journal. 33, 5, p. 6632-6642 11 p.

    Research output: Contribution to journalArticleResearchpeer-review

    8 Citations (Scopus)
  • 2018

    A GWAS meta-analysis from 5 population-based cohorts implicates ion channel genes in the pathogenesis of irritable bowel syndrome

    Bonfiglio, F., Henström, M., Nag, A., Hadizadeh, F., Zheng, T., Cenit, M. C., Tigchelaar, E., Williams, F., Reznichenko, A., Ek, W. E., Rivera, N. V., Homuth, G., Aghdassi, A. A., Kacprowski, T., Männikkö, M., Karhunen, V., Bujanda, L., Rafter, J., Wijmenga, C., Ronkainen, J. & 3 others, Hysi, P., Zhernakova, A. & D'Amato, M., 1 Sep 2018, In: Neurogastroenterology & Motility. 30, 9, 11 p., e13358.

    Research output: Contribution to journalArticleResearchpeer-review

    14 Citations (Scopus)
  • Female-Specific Association Between Variants on Chromosome 9 and Self-Reported Diagnosis of Irritable Bowel Syndrome

    Bonfiglio, F., Zheng, T., Garcia-Etxebarria, K., Hadizadeh, F., Bujanda, L., Bresso, F., Agreus, L., Andreasson, A., Dlugosz, A., Lindberg, G., Schmidt, P. T., Karling, P., Ohlsson, B., Simren, M., Walter, S., Nardone, G., Cuomo, R., Usai-Satta, P., Galeazzi, F., Neri, M. & 16 others, Portincasa, P., Bellini, M., Barbara, G., Latiano, A., Hübenthal, M., Thijs, V., Netea, M. G., Jonkers, D., Chang, L., Mayer, E. A., Wouters, M. M., Boeckxstaens, G., Camilleri, M., Franke, A., Zhernakova, A. & D'Amato, M., 1 Jul 2018, In: Gastroenterology. 155, 1, p. 168-179 12 p.

    Research output: Contribution to journalArticleResearchpeer-review

    Open Access
    File
    21 Citations (Scopus)
  • Functional variants in the sucrase-isomaltase gene associate with increased risk of irritable bowel syndrome

    Henström, M., Diekmann, L., Bonfiglio, F., Hadizadeh, F., Kuech, E. M., Von Köckritz-Blickwede, M., Thingholm, L. B., Zheng, T., Assadi, G., DIerks, C., Heine, M., Philipp, U., DIstl, O., Money, M. E., Belheouane, M., Heinsen, F. A., Rafter, J., Nardone, G., Cuomo, R., Usai-Satta, P. & 23 others, Galeazzi, F., Neri, M., Walter, S., Simrén, M., Karling, P., Ohlsson, B., Schmidt, P. T., Lindberg, G., Dlugosz, A., Agreus, L., Andreasson, A., Mayer, E., Baines, J. F., Engstrand, L., Portincasa, P., Bellini, M., Stanghellini, V., Barbara, G., Chang, L., Camilleri, M., Franke, A., Naim, H. Y. & D'Amato, M., 1 Feb 2018, In: Gut. 67, 2, p. 263-270 8 p.

    Research output: Contribution to journalArticleResearchpeer-review

    Open Access
    File
    52 Citations (Scopus)
  • Increased Prevalence of Rare Sucrase-isomaltase Pathogenic Variants in Irritable Bowel Syndrome Patients

    Garcia-Etxebarria, K., Zheng, T., Bonfiglio, F., Bujanda, L., Dlugosz, A., Lindberg, G., Schmidt, P. T., Karling, P., Ohlsson, B., Simren, M., Walter, S., Nardone, G., Cuomo, R., Usai-Satta, P., Galeazzi, F., Neri, M., Portincasa, P., Bellini, M., Barbara, G., Jonkers, D. & 10 others, Eswaran, S., Chey, W. D., Kashyap, P., Chang, L., Mayer, E. A., Wouters, M. M., Boeckxstaens, G., Camilleri, M., Franke, A. & D'Amato, M., 1 Oct 2018, In: Clinical Gastroenterology and Hepatology. 16, 10, p. 1673-1676 4 p.

    Research output: Contribution to journalArticleResearchpeer-review

    Open Access
    File
    23 Citations (Scopus)
  • 2015

    A preliminary study of plasma cyclase-associated protein 2 as a novel biomarker for early stage and alpha-fetoprotein negative hepatocellular carcinoma patients

    Chen, M., Zheng, T., Han, S., Zhang, L., Bai, Y., Fang, X., Ding, S. Z. & Yang, Y., 1 Apr 2015, In: Clinics and Research in Hepatology and Gastroenterology. 39, 2, p. 215-221 7 p.

    Research output: Contribution to journalArticleResearchpeer-review

    6 Citations (Scopus)
  • 2014

    Plasma minichromosome maintenance complex component 6 is a novel biomarker for hepatocellular carcinoma patients

    Zheng, T., Chen, M., Han, S., Zhang, L., Bai, Y., Fang, X., Ding, S. Z. & Yang, Y., 1 Jan 2014, In: Hepatology Research. 44, 13, p. 1347-1356 10 p.

    Research output: Contribution to journalArticleResearchpeer-review

    26 Citations (Scopus)
  • 2011

    Fluconazole inhibits hERG K+ channel by direct block and disruption of protein trafficking

    Han, S., Zhang, Y., Chen, Q., Duan, Y., Zheng, T., Hu, X., Zhang, Z. & Zhang, L., 10 Jan 2011, In: European Journal of Pharmacology. 650, 1, p. 138-144 7 p.

    Research output: Contribution to journalArticleResearchpeer-review

    35 Citations (Scopus)