20052021

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Personal profile

Biography

Dr. Tang received his doctoral degree from the Department of Pharmacology, University of Alberta. He then spent several years working as a research fellow at the Division of Neurodegenerative Disorders of the St. Boniface General Hospital Research Centre in Canada prior to joining Monash University Malaysia as a lecturer. Dr. Tang has won several national and international awards, including a scholarship award from the International Society of Neurochemistry, and the ‘Focus on Stroke’ Postdoctoral Fellowship Award from the Heart and Stroke Foundation of Canada. His current research interest focuses on the mechanisms underlying the brain cell death in neurodegenerative diseases.

Research interests

My current research interest mainly focuses on deciphering the mechanisms underlying brain cell death in neurodegenerative diseases. Previous studies have shown that oxidative stress plays a vital role in the pathophysiology of neurodegenerative diseases. Oxidative stress is induced by an imbalanced redox state, involving either the excessive generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system. Oxidative stress and excessive ROS production can cause homeostatic imbalance and lead to cellular dysfunction and eventual cell loss. The two classical cell death pathways are apoptosis and necrosis. Currently, there are many other contemporary pathways associated with cell death are being proposed. My laboratory employs pharmacological perturbation strategies in exploring the possible involvements of these cell death pathways in different disease models.

Monash teaching commitment

Bachelor of Pharmacy: PHR1031, PHR1022, PHR2042

Research area keywords

  • Pharmacology
  • Neuroscience
  • Endocrinology

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