Projects per year
Personal profile
Biography
Dr. Tang received his doctoral degree from the Department of Pharmacology, University of Alberta. He then spent several years working as a research fellow at the Division of Neurodegenerative Disorders of the St. Boniface General Hospital Research Centre in Canada prior to joining Monash University Malaysia as a lecturer. Dr. Tang has won several national and international awards, including a scholarship award from the International Society of Neurochemistry, and the ‘Focus on Stroke’ Postdoctoral Fellowship Award from the Heart and Stroke Foundation of Canada. His current research interest focuses on the mechanisms underlying the brain cell death in neurodegenerative diseases.
Research interests
My current research interest mainly focuses on deciphering the mechanisms underlying brain cell death in neurodegenerative diseases. Previous studies have shown that oxidative stress plays a vital role in the pathophysiology of neurodegenerative diseases. Oxidative stress is induced by an imbalanced redox state, involving either the excessive generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system. Oxidative stress and excessive ROS production can cause homeostatic imbalance and lead to cellular dysfunction and eventual cell loss. The two classical cell death pathways are apoptosis and necrosis. Currently, there are many other contemporary pathways associated with cell death are being proposed. My laboratory employs pharmacological perturbation strategies in exploring the possible involvements of these cell death pathways in different disease models.
Monash teaching commitment
Bachelor of Pharmacy: PHR1031, PHR1022, PHR2042
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Pharmacology
- Neuroscience
- Endocrinology
Network
-
Mechanistic studies on the cytoprotective potential of yttrium oxide nanoparticles against 6-hydroxydopamine-induced cellular model of Parkinson?s disease
Kim San, T., Ng, K. Y., Othman, I. & Teng, W. D.
1/11/20 → 31/10/23
Project: Research
-
Mechanistic studies to understand enzyme inhibition: Towards the development of new anti-HIV agents based on quinoline scaffold
Ahemad, N., SyedHassan, S., Ali Shah, S. A., Kim San, T., Htar, T. T. & Ahmad, M. N.
1/11/20 → 31/10/22
Project: Research
-
Exploring team-based teaching of basic sciences and clinical practice: Experiences of pharmacy students at a Malaysian pharmacy school
Tang, K. S., Maher, S. & Lee, S. W. H., 2023, (Accepted/In press) In: Medical Science Educator. 7 p.Research output: Contribution to journal › Article › Research › peer-review
-
Cellular and molecular events leading to paraquat-induced apoptosis: mechanistic insights into Parkinson’s disease pathophysiology
See, W. Z. C., Naidu, R. & Tang, K. S., Jun 2022, In: Molecular Neurobiology. 59, 6, p. 3353-3369 17 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile3 Citations (Scopus) -
Potential roles of α-amylase in alzheimer’s disease: Biomarker and drug target
Chen, W. N., Tang, K. S. & Yeong, K. Y., 2022, In: Current Neuropharmacology. 20, 8, p. 1554-1563 10 p.Research output: Contribution to journal › Review Article › Research › peer-review
1 Citation (Scopus) -
Antioxidant and anti-inflammatory properties of yttrium oxide nanoparticles: New insights into alleviating diabetes
Tang, K. S., 2021, In: Current Diabetes Reviews. 17, 4, p. 496-502 7 p.Research output: Contribution to journal › Review Article › Research › peer-review
2 Citations (Scopus) -
Protective effects of polydatin against dementia-related disorders
Tang, K. S., 2021, In: Current Neuropharmacology. 19, 2, p. 127-135 9 p.Research output: Contribution to journal › Review Article › Other › peer-review
12 Citations (Scopus)