Projects per year
Personal profile
Biography
Suzanne Orchard is a Senior Research Fellow in the School of Public Health and Preventive Medicine and the Director of the ASPREE Extension (ASPREE-XT) study since 2021. The ASPREE (ASPirin in Reducing Events in the Elderly) trial, the largest primary prevention aspirin study ever conducted in older Australians, commenced in 2010 and completed the intervention phase in 2017, after which it entered an extension or observational phase. Dr Orchard first joined the ASPREE study as manager of the ASPREE Healthy Ageing Biobank (2011) before moving to Senior Study Manager for the ASPREE trial (2013) and then Australian Operations manager (2015). Dr Orchard’s research focus is cancer epidemiology, public health and ageing.
Dr Orchard has a BSc (Biological Sciences; Hons, 1989) from La Trobe University, Melbourne, where she was awarded 'Young Women in Science' scholarship and later an Australian Postgraduate Award to undertake her PhD. Her thesis focussed on the interaction between fatty acyl-CoA synthetase enzymes and halogenated substrate derivatives, incorporating enzyme kinetics and inhibitor studies.
In 1998, Suzanne commenced work at the Ludwig Institute for Cancer Research (LICR), researching the role of the Epidermal Growth Factor Receptor in healthy and disease states, focussing on its expression, ligand binding properties and dimerization upon activation. During her decade at LICR, she developed expertise in the fields of molecular biology and cell signalling, biomarker research and small molecule inhibitor trials and collaborated with diverse research groups, internationally as well as local.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Biology, PhD, A Study of the Effect of Halogenated Fatty Acids on the Activity of the Short-Chain Fatty Acyl-CoA Synthetase of Plants in Relation to their Phytotoxicity., La Trobe University
1984 → 1997
Research area keywords
- Cancer survivorship, older adults, cancer, chemoprevention.
Collaborations and top research areas from the last five years
Projects
- 1 Active
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Prospective study of the gut microbiome in aging
Chan, A. T. (Primary Chief Investigator (PCI)), Woods, R. (Chief Investigator (CI)), Orchard, S. (Chief Investigator (CI)), Ryan, J. (Chief Investigator (CI)), Lacaze, P. (Chief Investigator (CI)) & McNeil, J. (Chief Investigator (CI))
15/09/20 → 31/03/26
Project: Research
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Antibiotic Use and Subsequent Cognitive Decline and Dementia Risk in Healthy Older Adults
Wang, Y., Zhou, Z., Broder, J. C., Woods, R. L., Orchard, S. G., Wolfe, R., Ernst, E. J., Ryan, J., Ernst, M. E. & Chan, A. T., 14 Jan 2025, In: Neurology. 104, 1, 10 p., e210129.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Aspirin and healthy lifespan in older people: main outcome of the ASPREE-XT observational study
Shah, R. C., Ryan, J. L., Webb, K. L., Wolfe, R., Chan, A., Chong, T. T. J., Ernst, M. E., Espinoza, S., Flynn, O., Lee, S. Y., McNeil, J. J., Nelson, M. R., Orchard, S. G., Reid, C. M., Sheets, K. M., Stocks, N. P., Weerasinghe, N., Wilson, M. E., Woods, R. L. & Murray, A., Sept 2025, In: The Lancet Healthy Longevity. 6, 9, 9 p., 100764.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Association Between Albuminuria and Glomerular Filtration Rate With Incident Frailty
Bongetti, E. K., Wilkinson, A. L., Wetmore, J. B., Murray, A. M., Woods, R. L., Espinoza, S., Ernst, M. E., Fravel, M. A., Orchard, S. G., Phuong Thao, L. T., Ryan, J., Wolfe, R. & Polkinghorne, K. R. (Leading Author), Feb 2025, In: Kidney International Reports. 10, 2, p. 489-502 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Association of Year-to-Year Lipid Variability With Risk of Cognitive Decline and Dementia in Community-Dwelling Older Adults
Zhou, Z., Moran, C., Murray, A. M., Zoungas, S., Magnussen, C., Chong, T. T. J., Shah, R. C., Sheets, K. M., Nelson, M., Zhu, C., Tonkin, A. M., Talic, S., Ernst, M. E., Orchard, S. G., Mcneil, J. J., Wolfe, R., Woods, R. L., Neumann, J. T., Qiu, P. & Ryan, J., 29 Jan 2025, In: Neurology. 104, 4, 16 p., e210247.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus) -
Associations between MASLD, atrial fibrillation, cardiovascular events, mortality and aspirin use in older adults
Clayton-Chubb, D., Roberts, S. K., Majeed, A., Woods, R. L., Tonkin, A. M., Nelson, M. R., Chan, A. T., Ryan, J., Tran, C., Hodge, A., Lubel, J. S., Schneider, H. G., Brodtmann, A., Fitzgerald, S. M., Orchard, S. G., McNeil, J. J. & Kemp, W. W., 2025, In: GeroScience. 47, p. 1303–1318 16 p.Research output: Contribution to journal › Article › Research › peer-review
10 Citations (Scopus)
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American Journal of Preventive Medicine (Journal)
Orchard, S. (Peer reviewer)
Feb 2024Activity: Publication peer-review and editorial work types › Peer review responsibility
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Communications Medicine (Journal)
Orchard, S. (Peer reviewer)
21 Aug 2024Activity: Publication peer-review and editorial work types › Peer review responsibility
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Cancers (Journal)
Orchard, S. (Peer reviewer)
12 Aug 2024Activity: Publication peer-review and editorial work types › Peer review responsibility
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The Lancet Healthy Longevity (Journal)
Orchard, S. (Peer reviewer)
2 May 2023Activity: Publication peer-review and editorial work types › Peer review responsibility
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Monash University
Orchard, S. (Organiser) & Kirpach, B. R. (Invited speaker)
30 Oct 2023Activity: Participating in or organising an event types › Contribution to conference
Press/Media
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Use of antibiotics in older adults and dementia risk.
3/01/25
2 Media contributions
Press/Media: Profile/Interview
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New Australian research links two ailments to early indication of dementia
7/10/22
1 item of Media coverage
Press/Media: Profile/Interview
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Surprise symptoms that can appear years before dementia
4/10/22
1 item of Media coverage
Press/Media: Article/Feature