1991 …2024

Research output per year

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Research Output

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Article

Discovery of benzoylsulfonohydrazides as potent inhibitors of the histone acetyltransferase KAT6A

Leaver, D. J., Cleary, B., Nguyen, N., Priebbenow, D., Lagiakos, H. R., Sanchez, J., Xue, L., Huang, F., Sun, Y., Mujumdar, P., Mudududdla, R., Varghese, S., Teguh, S., Charman, S. A., White, K. L., Katneni, K., Cuellar, M., Strasser, J. M., Dahlin, J. L., Walters, M. A. & 10 others, Street, I. P., Monahan, B. J., Jarman, K. E., Sabroux, H. J., Falk, H., Chung, M. C., Hermans, S. J., Parker, M. W., Thomas, T. & Baell, J. B., 8 Aug 2019, In : Journal of Medicinal Chemistry. 62, 15, p. 7146-7159 14 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Discovery of CYT997: a structurally novel orally active microtubule targeting agent

Burns, C., Harte, M., Bu, X., Fantino, E., Joffe, M., Sikanyika, H., Su, S., Tranberg, C. E., Wilson, N., Charman, S. A., Shackleford, D. & Wilks, A. F., 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 16, p. 4639 - 4642 4 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Discovery of novel benzo[ a ]phenoxazine SSJ-183 as a drug candidate for malaria

Ge, J-F., Arai, C., Yang, M., Bakar, A., Lu, J., Ismail, N. S. M., Wittlin, S., Kaiser, M., Brun, R., Charman, S. A., Nguyen, T., Morizzi, J., Itoh, I. & Ihara, M., 2010, In : ACS Medicinal Chemistry Letters. 1, 7, p. 360 - 364 5 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

Drug delivery: A key factor in realising the full therapeutic potential of drugs

Charman, W. N., Chan, H-K., Finnin, B. C. & Charman, S. A., 1999, In : Drug Development Research. 46, 3-4, p. 316-327 12 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Effect of dietary fatty acids on the intestinal permeability of marker drug compounds in excised rat jejunum

Vine, D. F., Charman, S. A., Gibson, P. R., Sinclair, A. J. & Porter, C. J. H., 2002, In : Journal of Pharmacy and Pharmacology. 54, 6, p. 809 - 819 11 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Effect of functional group polarity on the antimalarial activity of spiro and dispiro-1,2,4-trioxolanes

Dong, Y., Tang, Y., Chollet, J., Matile, H., Wittlin, S., Charman, S. A., Charman, W. N., Santo Tomas, J., Scheurer, C., Snyder, C., Scorneaux, B., Bajpai, S., Alexander, S. A., Wang, X., Padmanilayam, M., Cheruku, S. R., Brun, R. & Vennerstrom, J. L., 2006, In : Bioorganic & Medicinal Chemistry. 14, 18, p. 6368 - 6382 15 p.

Research output: Contribution to journalArticleResearchpeer-review

57 Citations (Scopus)

ELQ-300 prodrugs for enhanced delivery and single-dose cure of malaria

Miley, G. P., Pou, S., Winter, R., Nilsen, A., Li, Y., Kelly, J. X., Stickles, A. M., Mather, M. W., Forquer, I. P., Pershing, A. M., White, K., Shackleford, D., Saunders, J., Chen, G., Ting, L-M., Kim, K., Zakharov, L. N., Donini, C., Burrows, J. N., Valdya, A. B. & 2 others, Charman, S. A. & Riscoe, M. K., 2015, In : Antimicrobial Agents and Chemotherapy. 59, 9, p. 5555-5560 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
28 Citations (Scopus)

Enantiomers of nifurtimox do not exhibit stereoselective anti-Trypanosoma cruzi activity, toxicity, or pharmacokinetic properties

Moraes, C. B., White, K. L., Braillard, S., Perez, C., Goo, J., Gaspar, L., Shackleford, D. M., Cordeiro-da-Silva, A., Thompson, R. C. A., Freitas-Junior, L. H., Charman, S. A. & Chatelain, E., 2015, In : Antimicrobial Agents and Chemotherapy. 59, 6, p. 3645-3647 3 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access

Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis

Doggett, J. S., Nilsen, A., Forquer, I., Wegmann, K. W., Jones-Brando, L., Yolken, R. H., Bordon, C., Charman, S. A., Katneni, K., Schultz, T., Burrows, J., Hinrichs, D. J., Meunier, B., Carruthers, V. B. & Risco, M. K., 2012, In : Proceedings of the National Academy of Sciences. 109, 39, p. 15936 - 15941 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
79 Citations (Scopus)

Evaluation of 4-amino 2-anilinoquinazolines against Plasmodium and other apicomplexan parasites in vitro and in a P. Falciparum Humanized NOD-scid IL2R null Mouse Model of Malaria

Gilson, P. R., Nguyen, W., Poole, W. A., Teixeira, J. E., Thompson, J. K., Guo, K., Stewart, R. J., Ashton, T. D., White, K. L., Sanz, L. M., Gamo, F. J., Charman, S. A., Wittlin, S., Duffy, J., Tonkin, C. J., Tham, W. H., Crabb, B. S., Cooke, B. M., Huston, C. D., Cowman, A. F. & 1 others, Sleebs, B. E., 1 Mar 2019, In : Antimicrobial Agents and Chemotherapy. 63, 3, 15 p., e01804-18.

Research output: Contribution to journalArticleResearchpeer-review

Evaluation of emulsifiable glasses for the oral administration of cyclosporin in beagle dogs

Porter, C. J. H., Charman, S. A., Williams, R. D., Bakalova, M. V. & Charman, W. N., 6 Sep 1996, In : International Journal of Pharmaceutics. 141, 1-2, p. 227-237 11 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Evidence for the in vitro bioactivation of aminopyrazole derivatives: trapping reactive aminopyrazole intermediates using glutathione ethyl ester in human liver microsomes

Ryan, E., Morrow, B. J., Hemley, C. F., Pinson, J-A., Charman, S. A., Chiu, F. C. K. & Foitzik, R. C., 2015, In : Chemical Research in Toxicology. 28, 9, p. 1747-1752 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Falcipain Inhibitors Based on the Natural Product Gallinamide A Are Potent in Vitro and in Vivo Antimalarials

Stoye, A., Juillard, A., Tang, A. H., Legac, J., Gut, J., White, K. L., Charman, S. A., Rosenthal, P. J., Grau, G. E. R., Hunt, N. H. & Payne, R. J., 13 Jun 2019, In : Journal of Medicinal Chemistry. 62, 11, p. 5562-5578 17 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials

Moehrle, J., Duparc, S., Siethoff, C., van Giersbergen, P. L. M., Craft, C. J., Arbe-Barnes, S., Charman, S. A., Gutierrez, M., Wittlin, S. & Vennerstrom, J., Feb 2013, In : British Journal of Clinical Pharmacology. 75, 2, p. 524-537 14 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)

Fluorine modulates species selectivity in the triazolopyrimidine class of Plasmodium falciparum dihydroorotate dehydrogenase inhibitors

Deng, X., Kokkonda, S., El Mazouni, F., White, J., Burrows, J., Kaminsky, W., Charman, S. A., Matthews, D., Rathod, P. K. & Phillips, M. A., 2014, In : Journal of Medicinal Chemistry. 57, 12, p. 5381 - 5394 14 p.

Research output: Contribution to journalArticleResearchpeer-review

63 Citations (Scopus)

Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins

Xie, S. C., Dogovski, C., Hanssen, E., Chiu, F., Yang, T., Crespo, M. P., Stafford, C., Batinovic, S., Teguh, S., Charman, S., Klonis, N. & Tilley, L., 2016, In : Journal of Cell Science. 129, 2, p. 406-416 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
39 Citations (Scopus)

Hit-to-lead optimization of a novel class of potent, broad-spectrum trypanosomacides

Russell, S., Rahmani, R., Jones, A. J., Newson, H. L., Neilde, K., Cotillo, I., Rahmani Khajouei, M., Ferrins, L., Qureishi, S., Nguyen, N., Martinez-Martinez, M. S., Weaver, D. F., Kaiser, M., Riley, J., Thomas, J., De Rycker, M., Read, K. D., Flematti, G. R., Ryan, E., Tanghe, S. & 6 others, Rodriguez, A., Charman, S. A., Kessler, A., Avery, V. M., Baell, J. B. & Piggott, M. J., 10 Nov 2016, In : Journal of Medicinal Chemistry. 59, 21, p. 9686-9720 35 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice

Gujjar, R., Marwaha, A., El Mazouni, F., White, J., White, K. L., Creason, S., Shackleford, D., Baldwin, J., Charman, W. N., Buckner, F. S., Charman, S. A., Rathod, P. & Phillips, M., 2009, In : Journal of Medicinal Chemistry. 52, 7, p. 1864 - 1872 9 p.

Research output: Contribution to journalArticleResearchpeer-review

157 Citations (Scopus)

Identification of an antimalarial synthetic trioxolane drug development candidate

Vennerstrom, J. L., Arbe-Barnes, S., Brun, R., Charman, S. A., Chiu, F. C. K., Chollet, J., Dong, Y., Dorn, A., Hunziker, D., Matile, H., McIntosh, K. A., Padmanilayam, M., Santo Tomas, J., Scheurer, C., Scorneaux, B., Tang, Y., Urwyler, H., Wittlin, S. & Charman, W. N., 19 Aug 2004, In : Nature. 430, 7002, p. 900-904 5 p.

Research output: Contribution to journalArticleResearchpeer-review

526 Citations (Scopus)

Identification of a potential antimalarial drug candidate from a series of 2-aminopyrazines by optimization of aqueous solubility and potency across the parasite life cycle

Le Manach, C., Nchinda, A. T., Paquet, T., Gonzàlez Cabrera, D., Younis, Y., Han, Z., Bashyam, S., Zabiulla, M., Taylor, D., Lawrence, N., White, K. L., Charman, S. A., Waterson, D., Witty, M. J., Wittlin, S., Botha, M. E., Nondaba, S. H., Reader, J., Birkholtz, L. M. & Jiménez-Díaz, M. B., 10 Nov 2016, In : Journal of Medicinal Chemistry. 59, 21, p. 9890-9905 16 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Inhibition of cytomegalovirus replication with extended-half-life synthetic ozonides

Wang, Y., Mukhopadhyay, R., Roy, S., Kapoor, A., Su, Y. P., Charman, S. A., Chen, G., Wu, J., Wang, X., Vennerstrom, J. L. & Arav-Boger, R., 1 Jan 2019, In : Antimicrobial Agents and Chemotherapy. 63, 1, 14 p., e01735-18.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT): cocrystal structures of pyrazolopyrans with potent blood- and liver-stage activities

Witschel, M. C., Rottmann, M., Schwab, A., Leartsakulpanich, U., Chitnumsub, P., Seet, M., Tonazzi, S., Schwertz, G., Stelzer, F., Mietzner, T., McNamara, C., Thater, F., Freymond, C., Jaruwat, A., Pinthong, C., Riangrungroj, P., Oufir, M., Hamburger, M., Maser, P., Sanz-Alonso, L. M. & 5 others, Charman, S., Wittlin, S., Yuthavong, Y., Chaiyen, P. & Diederich, F., 2015, In : Journal of Medicinal Chemistry. 58, 7, p. 3117-3130 14 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

In vitro and in vivo characterization of the antimalarial lead compound SSJ-183 in Plasmodium models

Schleiferbock, S., Scheurer, C., Ihara, M., Itoh, I., Bathurst, I. C., Burrows, J., Fantauzzi, P., Lotharius, J., Charman, S. A., Morizzi, J., Shackleford, D., White, K. L., Brun, R. & Wittlin, S., 2013, In : Drug Design, Development and Therapy. 7, p. 1377 - 1384 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
7 Citations (Scopus)

In vitro assessment of the pharmacodynamic properties and the partitioning of OZ277/RBx-11160 in cultures of Plasmodium falciparum

Maerki, S., Brun, R., Charman, S. A., Dorn, A., Matile, H. & Wittlin, S., 2006, In : Journal of Antimicrobial Chemotherapy. 58, 1, p. 52 - 58 7 p.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

Iron-mediated degradation kinetics of substituted dispiro-1,2,4-trioxolane antimalarials

Creek, D. J., Charman, W. N., Chiu, F. C. K., Prankerd, R. J., McCullough, K. J., Dong, Y., Vennerstrom, J. & Charman, S. A., 2007, In : Journal of Pharmaceutical Sciences. 96, 11, p. 2945 - 2956 12 p.

Research output: Contribution to journalArticleResearchpeer-review

47 Citations (Scopus)

Isoxazolopyrimidine-Based Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Antimalarial Activity

Kokkonda, S., El Mazouni, F., White, K. L., White, J., Shackleford, D. M., Lafuente-Monasterio, M. J., Manjalanagara, K., Joseph, J. T., Garcia-Pérez, A., Fernandez, J., Gamo, F. J., Waterson, D., Burrows, J. N., Palmer, M. J., Charman, S. A., Rathod, P. K. & Phillips, M. A., Aug 2018, In : ACS Omega. 3, 8, p. 9227-9240 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)

Kinetics of iron-mediated artemisinin degradation: effect of solvent composition and iron salt

Creek, D. J., Chiu, F. C. K., Prankerd, R. J., Charman, S. A. & Charman, W. N., 2005, In : Journal of Pharmaceutical Sciences. 94, 8, p. 1820 - 1829 10 p.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice

Gujjar, R., El Mazouni, F., White, K., White, J., Creason, S., Shackleford, D., Deng, X., Charman, W., Bathurst, I., Burrows, J., Floyd, D., Matthews, D., Buckner, F., Charman, S., Phillips, M. & Rathod, P., 2011, In : Journal of Medicinal Chemistry. 54, p. 3935 - 3949 15 p.

Research output: Contribution to journalArticleResearchpeer-review

105 Citations (Scopus)

Long-Lasting and Fast-Acting in Vivo Efficacious Antiplasmodial Azepanylcarbazole Amino Alcohol

Abla, N., Bashyam, S., Charman, S. A., Greco, B., Hewitt, P., Jiménez-Díaz, M. B., Katneni, K., Kubas, H., Picard, D., Sambandan, Y., Sanz, L., Smith, D., Wang, T., Willis, P., Wittlin, S. & Spangenberg, T., 14 Dec 2017, In : ACS Medicinal Chemistry Letters. 8, 12, p. 1304-1308 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Lymphatic absorption is a significant contributor to the subcutaneous bioavailability of insulin in a sheep model

Charman, S. A., McLennan, D. N., Edwards, G. & Porter, C. J. H., 2001, In : Pharmaceutical Research. 18, 11, p. 1620-1626 7 p.

Research output: Contribution to journalArticleResearchpeer-review

46 Citations (Scopus)

Lymphatic absorption is the primary contributor to the systemic availability of epoetin alfa following subcutaneous administration to sheep

McLennan, D. N., Porter, C. J. H., Edwards, G. A., Martin, S. W., Heatherington, A. C. & Charman, S. A., 2005, In : Journal of Pharmacology and Experimental Therapeutics. 313, 1, p. 345 - 351 7 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

Lymphatic absorption of subcutaneously administered proteins: influence of different injection sites on the absorption of darbepoetin alfa using a sheep model

Kota, J., Machavaram, K. K., McLennan, D. N., Edwards, G. A., Porter, C. J. & Charman, S. A., 2007, In : Drug Metabolism and Disposition. 35, 12, p. 2211 - 2217 7 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)
113 Citations (Scopus)

Lymphatic transport of proteins after s.c. injection: Implications of animal model selection

Porter, C. J. H., Edwards, G. & Charman, S. A., 23 Aug 2001, In : Advanced Drug Delivery Reviews. 50, 1-2, p. 157-171 15 p.

Research output: Contribution to journalArticleResearchpeer-review

78 Citations (Scopus)

Lymphatic transport of proteins after subcutaneous administration

Porter, C. J. H. & Charman, S. A., Mar 2000, In : Journal of Pharmaceutical Sciences. 89, 3, p. 297-310 14 p.

Research output: Contribution to journalArticleResearchpeer-review

173 Citations (Scopus)

Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target

Yuthavong, Y., Tarnchompoo, B., Vilaivan, T., Chitnumsub, P., Kamchonwongpaisan, S., Charman, S. A., McLennan, D. N., White, K. L., Vivas, L., Bongard, E., Thongphanchang, C., Taweechai, S., Vanichtanankul, J., Rattanajak, R., Arwon, U., Fantauzzi, P., Yuvaniyama, J., Charman, W. N. & Matthews, D., 2012, In : Proceedings of the National Academy of Sciences. 109, 42, p. 16823 - 16828 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
116 Citations (Scopus)

Mechanisms controlling diffusion and release of model proteins through and from partially esterified hyaluronic acid membranes

Simon, L. D., Stella, V. J., Charman, W. N. & Charman, S. A., 20 Sep 1999, In : Journal of Controlled Release. 61, 3, p. 267-279 13 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a SoftFocus kinase library: Part 1

Le Manach, C., Cabrera, D. G., Douelle, F., Nchinda, A. T., Younis, Y., Taylor, D., Wiesner, L., White, K. L., Ryan, E., March, C., Duffy, S., Avery, V. M., Waterson, D., Witty, M. J., Wittlin, S., Charman, S. A., Street, L. J. & Chibale, K., 2014, In : Journal of Medicinal Chemistry. 57, 6, p. 2789 - 2798 10 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Metallocene-based inhibitors of cancer-associated carbonic anhydrase enzymes IX and XII

Salmon, A. J., Williams, M. L., Wu, Q. K., Morizzi, J., Gregg, D. J., Charman, S. A., Vullo, D., Supuran, C. T. & Poulsen, S-A., 2012, In : Journal of Medicinal Chemistry. 55, 11, p. 5506 - 5517 12 p.

Research output: Contribution to journalArticleResearchpeer-review

60 Citations (Scopus)

Methods to assess drug permeability across the blood-brain barrier

Nicolazzo, J. A., Charman, S. A. & Charman, W. N., 2006, In : Journal of Pharmacy and Pharmacology. 58, 3, p. 281 - 293 13 p.

Research output: Contribution to journalArticleResearchpeer-review

83 Citations (Scopus)

Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage

Francisco, A. F., Jayawardhana, S., Lewis, M. D., White, K. L., Shackleford, D. M., Chen, G., Saunders, J., Osuna-Cabello, M., Read, K. D., Charman, S. A., Chatelain, E. & Kelly, J. M., 17 Oct 2016, In : Scientific Reports. 6, 11 p., 35351.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
27 Citations (Scopus)

Novel Human Aminopeptidase N Inhibitors: Discovery and Optimization of Subsite Binding Interactions

Lee, J., Vinh, N. B., Drinkwater, N., Yang, W., Kannan Sivaraman, K., Schembri, L. S., Gazdik, M., Grin, P. M., Butler, G. S., Overall, C. M., Charman, S. A., McGowan, S. & Scammells, P. J., 8 Aug 2019, In : Journal of Medicinal Chemistry. 62, 15, p. 7185-7209 25 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Novel inhibitors of Plasmodium falciparum based on 2,5-disubstituted furans

Krake, S. H., Martinez, P. D. G., McLaren, J., Ryan, E., Chen, G., White, K., Charman, S. A., Campbell, S., Willis, P. & Dias, L. C., 27 Jan 2017, In : European Journal of Medicinal Chemistry. 126, p. 929-936 8 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Novel orally active antimalarial thiazoles

Cabera, D., Douelle, F., Feng, T-S., Nchinda, A., Younis, Y., White, K., Wu, Q., Ryan, E., Burrows, J., Waterson, D., Witty, M., Wittlin, S., Charman, S. & Chibale, K., 2011, In : Journal of Medicinal Chemistry. 54, p. 7713 - 7719 7 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

Novel Toxoplasma gondii inhibitor chemotypes

Sanford, A. G., Schulze, T. T., Potluri, L. P., Hemsley, R. M., Larson, J. J., Judge, A. K., Zach, S. J., Wang, X., Charman, S. A., Vennerstrom, J. L. & Davis, P. H., 1 Apr 2018, In : Parasitology International. 67, 2, p. 107-111 5 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Open source drug discovery: Highly potent antimalarial compounds derived from the tres cantos arylpyrroles

Williamson, A. E., Ylioja, P. M., Robertson, M. N., Antonova-Koch, Y., Avery, V., Baell, J., Batchu, H., Batra, S., Burrows, J. N., Bhattacharyya, S., Calderon, F., Charman, S., Clark, J., Crespo, B., Dean, M., Debbert, S. L., Delves, M. J., Dennis, A. S. M., Deroose, F., Duffy, S. & 3 others, Ryan, E., Wells, T. & White, K., 26 Oct 2016, In : ACS Central Science. 2, 10, p. 687-701 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
27 Citations (Scopus)

Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium

Cross, M., Flanigan, D. L., Monastyrskyi, A., LaCrue, A. N., Saenz, F. E., Maignan, J. R., Mutka, T. S., White, K. L., Shackleford, D., Bathurst, I. C., Fronczek, F. R., Wojtas, L., Guida, W. C., Charman, S. A., Burrows, J., Kyle, D. E. & Manetsch, R., 2014, In : Journal of Medicinal Chemistry. 57, 21, p. 8860 - 8879 20 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Ozonide Antimalarials Alkylate Heme in the Malaria Parasite Plasmodium falciparum

Giannangelo, C., Anderson, D., Wang, X., Vennerstrom, J. L., Charman, S. A. & Creek, D. J., 17 Oct 2019, In : ACS Infectious Diseases. 5, 12, p. 2076-2086 11 p.

Research output: Contribution to journalArticleResearchpeer-review