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Research Output 2001 2019

2019

A Synthetic Nanoparticle Based Vaccine Approach Targeting MSP4/5 Is Immunogenic and Induces Moderate Protection Against Murine Blood-Stage Malaria

Wilson, K. L., Pouniotis, D., Hanley, J., Xiang, S. D., Ma, C., Coppel, R. L. & Plebanski, M., 15 Mar 2019, In : Frontiers in Immunology. 10, 12 p., 331.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2018

Design of Peptide-Based Nanovaccines Targeting Leading Antigens From Gynecological Cancers to Induce HLA-A2.1 Restricted CD8 + T Cell Responses

Xiang, S. D., Wilson, K. L., Goubier, A., Heyerick, A. & Plebanski, M., 1 Dec 2018, In : Frontiers in Immunology. 9, 17 p., 2968.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Immunotherapeutic Interleukin-6 or Interleukin-6 Receptor Blockade in Cancer: Challenges and Opportunities

Kampan, N. C., Xiang, S. D., McNally, O. M., Stephens, A. N., Quinn, M. A. & Plebanski, M., 1 Jan 2018, In : Current Medicinal Chemistry. 25, 36, p. 4785-4806 22 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Sperm protein 17 expression by murine epithelial ovarian cancer cells and its impact on tumor progression

Gao, Q., Xiang, S. D., Wilson, K., Madondo, M., Stephens, A. N. & Plebanski, M., 20 Aug 2018, In : Cancers. 10, 8, 15 p., 276.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2017

Design of nanoparticle structures for cancer immunotherapy

Tsirikis, P., Xiang, S. D., Selomulya, C. & Plebanski, M., 14 Apr 2017, Nanostructures for Cancer Therapy. Ficai, A. & Grumezescu, A. M. (eds.). Amsterdam Netherlands: Elsevier, p. 307-328 22 p. (Nanostructures in Therapeutic Medicine Series; vol. 4).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Engineered hydrogen-bonded glycopolymer capsules and their interactions with antigen presenting cells

Kempe, K., Xiang, S. D., Wilson, P., Rahim, M. A., Ju, Y., Whittaker, M. R., Haddleton, D. M., Plebanski, M., Caruso, F. & Davis, T. P., 22 Feb 2017, In : ACS Applied Materials and Interfaces. 9, 7, p. 6444-6452 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Exacerbation of Ventilation-Induced Lung Injury and Inflammation in Preterm Lambs by High-Dose Nanoparticles

Inocencio, I. M., Bischof, R. J., Xiang, S. D., Zahra, V. A., Nguyen, V., Lim, T., Larosa, D., Barbuto, J., Tolcos, M., Plebanski, M., Polglase, G. R. & Moss, T. J., 1 Dec 2017, In : Scientific Reports. 7, 1, 10 p., 14704.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Immunological effects among workers who handle engineered nanoparticles

Glass, D. C., Mazhar, M., Xiang, S., Dean, P., Simpson, P., Priestly, B., Plebanski, M., Abramson, M., Sim, M. R. & Dennekamp, M., 1 Dec 2017, In : Occupational and Environmental Medicine. 74, 12, p. 868-876 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Magnetic nanovectors for the development of DNA blood-stage malaria vaccines

Nawwab Al-Deen, F. M., Xiang, S. D., Ma, C., Wilson, K., Coppel, R., Selomulya, C. & Plebanski, M., 10 Feb 2017, In : Nanomaterials. 7, 2, 17 p., 30.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Understanding CD8+ T-cell responses toward the native and alternate HLA-A02:01-restricted WT1 epitope

Nguyen, T., Tan, A. CL., Xiang, S. D., Goubier, A., Harland, K. L., Clemens, E. B., Plebanski, M. & Kedzierska, K., 1 Jan 2017, In : Clinical and Translational Immunology. 6, 3, 12 p., e134.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2016
Open Access
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Inflammatory/Noninflammatory Adjuvants and Nanotechnology-The Secret to Vaccine Design

Wilson, K. L., Xiang, S. D. & Plebanski, M., 29 Sep 2016, Micro- and Nanotechnology in Vaccine Development. Skwarczynski, M. & Toth, I. (eds.). Kidlington Oxford UK: Elsevier, p. 99-125 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Nanoparticles, immunomodulation and vaccine delivery

Xiang, S. D., Fuchsberger, M., Karlson, T. D. L., Hardy, C. L., Selomulya, C. & Plebanski, M., 1 Apr 2016, Engineered Nanomaterials and the Immune Cell Function. World Scientific Publishing, Vol. 3. p. 101-127 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2015

A nanoparticle based Sp17 peptide vaccine exposes new immuno-dominant and species cross-reactive B cell epitopes

Xiang, S. D., Gao, Q., Wilson, K. L., Heyerick, A. & Plebanski, M., 29 Oct 2015, In : Vaccines. 3, 4, p. 875-893 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Mapping T and B cell epitopes in sperm protein 17 to support the development of an ovarian cancer vaccine

Xiang, S. D., Gao, Q., Wilson, K. L., Heyerick, A. & Plebanski, M., 4 Nov 2015, In : Vaccine. 33, 44, p. 5950-5959 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Nanoparticles modify dendritic cell homeostasis and induce non-specific effects on immunity to malaria

Xiang, S. D., Kong, Y. Y., Hanley, J., Fuchsberger, M., Crimeen-Irwin, B. & Plebanski, M., 7 Jan 2015, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 109, 1, p. 70-76 7 p.

Research output: Contribution to journalArticleResearchpeer-review

The use of synthetic carriers in malaria vaccine design

Powles, L. M., Xiang, S. D., Selomulya, C. & Plebanski, M., 29 Oct 2015, In : Vaccines. 3, 4, p. 894 - 929 36 p.

Research output: Contribution to journalArticleResearchpeer-review

2014

Design of magnetic polyplexes taken up efficiently by dendritic cell for enhanced DNA vaccine delivery

Nawwab Al-Deen, F. M., Selomulya, C., Kong, Y. Y., Xiang, S. D., Ma, C. W. C., Coppel, R. L. & Plebanski, M., 2014, In : Gene Therapy. 21, 2, p. 212 - 218 7 p.

Research output: Contribution to journalArticleResearchpeer-review

The effects of engineered nanoparticles on pulmonary immune homeostasis

Mohamud, R., Xiang, S. D., Selomulya, C., Rolland, J. M., O'Hehir, R. E., Hardy, C. L. & Plebanski, M., 2014, In : Drug Metabolism Reviews. 46, 2, p. 176 - 190 15 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

Differential uptake of nanoparticles and microparticles by pulmonary APC subsets induces discrete immunological imprints

Hardy, C. L., LeMasurier, J., Mohamud, R., Yao, J. J., Xiang, S. D., Rolland, J. M., O'Hehir, R. E. & Plebanski, M., 2013, In : Journal of Immunology. 191, 10, p. 5278 - 5290 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Methods of effective conjugation of antigens to nanoparticles as non-inflammatory vaccine carriers

Xiang, S. D., Wilson, K., Day, S., Fuchsberger, M. & Plebanski, M., 2013, In : Methods. 60, 3, p. 232 - 241 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Myeloid derived suppressor cells and their role in diseases

Kong, Y. Y., Fuchsberger, M., Xiang, S. D., Apostolopoulos, V. & Plebanski, M., 2013, In : Current Medicinal Chemistry. 20, 11, p. 1437 - 1444 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Nanoparticles, immunomodulation and vaccine delivery

Xiang, S. D., Fuchsberger, M., Karlson, T. D. L., Hardy, C. L., Selomulya, C. & Plebanski, M., 2013, Handbook of Immunological Properties of Engineered Nanomaterials. Dobrovolskaia, M. A. & McNeil, S. E. (eds.). USA: World Scientific Publishing, p. 449 - 476 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Nanotechnology and vaccine development: Methods to study and manipulate the interaction of nanoparticles with the immune system

Plebanski, M. & Xiang, S. D., 1 May 2013, In : Methods. 60, 3, p. 225 1 p.

Research output: Contribution to journalEditorialOtherpeer-review

On the efficacy of malaria DNA vaccination with magnetic gene vectors

Nawwab Al-Deen, F. M., Ma, C. W. C., Xiang, S. D., Selomulya, C., Plebanski, M. & Coppel, R. L., 2013, In : Journal of Controlled Release. 168, 1, p. 10 - 17 8 p.

Research output: Contribution to journalArticleResearchpeer-review

The signalling imprints of nanoparticle uptake by bone marrow derived dendritic cells

Karlson, T. D. L., Kong, Y. Y., Hardy, C. L., Xiang, S. D. & Plebanski, M., 2013, In : Methods. 60, 3, p. 275 - 283 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2012

Inert 50-nm polystyrene nanoparticles that modify pulmonary dendritic cell function and inhibit allergic airway inflammation

Hardy, C., LeMasurier, J., Belz, G., Scalzo-Inguanti, K., Yao, J. J., Xiang, S., Kanellakis, P., Bobik, A., Strickland, D. H., Rolland, J., O'Hehir, R. & Plebanski, M., 2012, In : Journal of Immunology. 188, 3, p. 1431 - 1441 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Substantially modified ratios of effector to regulatory T cells during chemotherapy in ovarian cancer patient return to pre-treatment levels at completion: implications for immunology

Park, A., Govindaraj, C., Xiang, S. D., Halo, J., Quinn, M., Scalzo-Inguanti, K. & Plebanski, M., 2012, In : Cancers. 4, 2, p. 581 - 600 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2011

N,N'-Carbonyldiimidazole-mediated functionalization of superparamagnetic nanoparticles as vaccine carrier

Ho, J., Nawwab Al-Deen, F. M., Al-Abboodi, A., Selomulya, C., Xiang, S., Plebanski, M. & Forde, G., 2011, In : Colloids and Surfaces B: Biointerfaces. 83, 1, p. 83 - 90 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2010

Delivery of DNA vaccines: an overview on the use of biodegradable polymeric and magnetic nanoparticles

Xiang, S. D., Selomulya, C., Ho, J., Apostolopoulos, V. & Plebanski, M., 2010, In : Wiley Interdisciplinary Reviews:Nanomedicine and Nanobiotechnology. 2, 3, p. 205 - 218 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Methods to measure T-cell responses

Plebanski, M., Katsara, M., Sheng, K-C., Xiang, S. & Apostolopoulos, V., 2010, In : Expert Review of Vaccines. 9, 6, p. 595 - 600 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2008

Investigation of a novel approach to scoring Giemsa-stained malaria-infected thin blood films

Proudfoot, O., Drew, N., Scholzen, A., Xiang, S. D. & Plebanski, M., 2008, In : Malaria Journal. 7, 62, p. 1 - 6 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Promising particle-based vaccines in cancer therapy

Xiang, S. D., Scalzo-Inguanti, K., Minigo, G., Park, A., Hardy, C. L. & Plebanski, M., 2008, In : Expert Review of Vaccines. 7, 7, p. 1103 - 1119 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Vaccination against foot-and-mouth disease virus using peptides conjugated to nano-beads

Greenwood, D. L., Dynon, K., Kalkanidis, M., Xiang, S. D., Plebanski, M. & Scheerlinck, J-P., 2008, In : Vaccine. 26, 22, p. 2706 - 2713 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2007

Type 1 and 2 immunity following vaccination is influenced by nanoparticle size: formulation of a model vaccine for respiratory syncytial virus

Mottram, P. L., Leong, D., Crimeen-Irwin, B., Gloster, S., Xiang, S. D., Meanger, J., Ghildyal, R., Vardaxis, N. J. & Plebanski, M., 2007, In : Molecular Pharmaceutics. 4, 1, p. 73 - 84 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2006

Methods for nano-particle based vaccine formulation and evaluation of their immunogenicity

Kalkanidis, M., Pietersz, G. A., Xiang, S. D., Mottram, P. L., Crimeen-Irwin, B., Ardipradja, K. & Plebanski, M., 2006, In : Methods. 40, 1, p. 20 - 29 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Pathogen recognition and development of particulate vaccines: Does size matter?

Xiang, S. D., Scholzen, A., Minigo, G., David-Shields, C. T., Apostolopoulos, V., Mottram, P. L. & Plebanski, M., 2006, In : Methods. 40, 1, p. 1 - 9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2004

Vaccines that facilitate antigen entry into dendritic cells

Gamvrellis, A., Leong, D., Hanley, J. C., Xiang, S. D., Mottram, P. L. & Plebanski, M., 2004, In : Immunology and Cell Biology. 82, 5, p. 506 - 516 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2003

Physiologic determinants of endothelin concentrations in human saliva

Xiang, S., Denver, R. A., Bailey, M. J. & Krum, H., 2003, In : Clinical Chemistry. 49, 12, p. 2012 - 2019 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Quantitative phase imaging: Extending imaging capability

Xiang, S., Allman, B. & Porter, C., 2003, In : American Laboratory. 35, 3, p. 58 - 67 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2001

Tracking membrane and secretory immunoglobulin alpha heavy chain mRNA variation during B-cell differentiation by real-time quantitative polymerase chain reaction

Xiang, S., Benson, E. & Dunn, I., 2001, In : Immunology and Cell Biology. 79, 5, p. 472 - 481 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Tracking membrane and secretory immunoglobulina α heavy chain mRNA variation during B-cell differentiation by real-time quantitative polymerase chain reaction

Xiang, S. D., Benson, E. M. & Dunn, I. S., 1 Dec 2001, In : Immunology and Cell Biology. 79, 5, p. 472-481 10 p.

Research output: Contribution to journalArticleResearchpeer-review