20072019
If you made any changes in Pure these will be visible here soon.

Research Output 2007 2019

Filter
Article
2019

DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns

Skvortsova, K., Masle-Farquhar, E., Luu, P. L., Song, J. Z., Qu, W., Zotenko, E., Gould, C. M., Du, Q., Peters, T. J., Colino-Sanguino, Y., Pidsley, R., Nair, S. S., Khoury, A., Smith, G. C., Miosge, L. A., Reed, J. H., Kench, J. G., Rubin, M. A., Horvath, L., Bogdanovic, O. & 5 othersLim, S. M., Polo, J. M., Goodnow, C. C., Stirzaker, C. & Clark, S. J., 11 Feb 2019, In : Cancer Cell. 35, 2, p. 297-314 18 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

Fine Tuning of Canonical Wnt Stimulation Enhances Differentiation of Pluripotent Stem Cells Independent of β-Catenin-Mediated T-Cell Factor Signaling

Chen, J., Nefzger, C. M., Rossello, F., Sun, Y. B. Y., Lim, S. M., Liu, X., De Boer, S., Knaupp, A. S., Li, J., Davidson, K. C., Polo, J. M. & Barberi, T., 1 Jun 2018, In : Stem Cells. 36, 6, p. 822-833 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2017

Cell Type of Origin Dictates the Route to Pluripotency

Nefzger, C. M., Rossello, F. J., Chen, J., Liu, X., Knaupp, A. S., Firas, J., Paynter, J. M., Pflueger, J., Buckberry, S., Lim, S. M., Williams, B., Alaei, S., Faye-Chauhan, K., Petretto, E., Nilsson, S. K., Lister, R., Ramialison, M., Powell, D. R., Rackham, O. J. L. & Polo, J. M., 5 Dec 2017, In : Cell Reports. 21, 10, p. 2649-2660 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Transient and Permanent Reconfiguration of Chromatin and Transcription Factor Occupancy Drive Reprogramming

Knaupp, A. S., Buckberry, S., Pflueger, J., Lim, S. M., Ford, E., Larcombe, M. R., Rossello, F. J., de Mendoza, A., Alaei, S., Firas, J., Holmes, M. L., Nair, S. S., Clark, S. J., Nefzger, C. M., Lister, R. & Polo, J. M., 7 Dec 2017, In : Cell Stem Cell. 21, 6, p. 834-845.e6 18 p.

Research output: Contribution to journalArticleResearchpeer-review

2016

An improved reprogrammable mouse model harbouring the reverse tetracycline-controlled transcriptional transactivator 3

Alaei, S., Knaupp, A. S., Lim, S. M., Chen, J., Holmes, M. L., Ankö, M-L., Nefzger, C. M. & Polo, J. M., 1 Jul 2016, In : Stem Cell Research. 17, 1, p. 49-53 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2015

Productive infection of human embryonic stem cell-derived NKX2.1+ respiratory progenitors with human rhinovirus

Jenny, R. A., Hirst, C. E., Lim, S. M., Goulburn, A. L., Micallef, S. J., Labonne, T., Kicic, A., Ling, K-M., Stick, S., Ng, E. S. S., Trounson, A. O., Giudice, A., Elefanty, A. G. & Stanley, E. G., 2015, In : Stem Cells Translational Medicine. 4, 6, p. 603 - 614 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Transcription factor-mediated reprogramming: epigenetics and therapeutic potential

Firas, J., Liu, E. X., Lim, S. M. & Polo, J. M., 2015, In : Immunology and Cell Biology. 93, 3, p. 284 - 289 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

Derivation of endothelial cells from human embryonic stem cells in fully defined medium enables identification of lysophosphatidic acid and platelet activating factor as regulators of eNOS localization

Costa, M., Sourris, K., Lim, S. M., Yu, Q. C., Hirst, C. E., Parkington, H. C., Jameson-Jokubaitis, V. J., Dear, A. E., Liu, H. B., Micallef, S. J., Koutsis, K., Elefanty, A. G. & Stanley, E., 2013, In : Stem Cell Research. 10, 1, p. 103 - 117 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2012

A molecular roadmap of reprogramming somatic cells into iPS cells

Polo, J. M., Anderssen, E., Walsh, R. M., Schwarz, B. A., Nefzger, C., Lim, S. M., Borkent, M., Apostolou, E., Alaei Shehni, S., Cloutier, J., Bar-Nur, O., Cheloufi, S., Stadtfeld, M., Figueroa, M. E., Robinton, D., Natesan, S., Melnick, A., Zhu, J., Ramaswamy, S. & Hochedlinger, K., 2012, In : Cell. 151, 7, p. 1617 - 1632 16 p.

Research output: Contribution to journalArticleResearchpeer-review

INS (GFP/w) human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cells

Micallef, S. J., Li, X., Schiesser, J. V., Hirst, C. E., Yu, Q. C., Lim, S. M., Nostro, M. C., Elliott, D. A., Sarangi, F., Harrison, L. C., Keller, G., Elefanty, A. G. & Stanley, E. G., 2012, In : Diabetologia. 55, 3, p. 694 - 706 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Pdgfr{alpha} and Flk1 are direct target genes of Mixl1 in differentiating embryonic stem cells

Pereira, L. A., Wong, M., Mossman, A. K., Sourris, K., Janes, M. E., Knezevic, K., Hirst, C. E., Lim, S. M., Pimanda, J. E., Stanley, E. G. & Elefanty, A. G., 2012, In : Stem Cell Research. 8, 2, p. 165 - 179 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Temporal restriction of pancreatic branching competence during embryogenesis is mirrored In differentiating embryonic stem cells

Lim, S. M., Li, X., Schiesser, J. V., Holland, A. M., Elefanty, A. G., Stanley, E. G. & Micallef, S. J., 2012, In : Stem Cells and Development. 21, 10, p. 1662 - 1674 13 p.

Research output: Contribution to journalArticleResearchpeer-review

The Mix family of homeobox genes-key regulators of mesendoderm formation during vertebrate development

Pereira, L. A., Wong, M. S., Lim, S. M., Stanley, E. G. & Elefanty, A. G., 2012, In : Developmental Biology. 367, 2, p. 163 - 177 15 p.

Research output: Contribution to journalArticleResearchpeer-review

2011

A targeted NKX2.1 hesc reporter line enables identification of human basal forebrain derivatives

Goulburn, A., Alden, D., Davis, R. P., Micallef, S. J., Ng, E. S., Yu, Q. C., Lim, S. M., Soh, C-L., Elliott, D., Hatzistavrou, T., Bourke, J., Watmuff, B., Lang, R. J., Haynes, J. M., Pouton, C. W., Giudice, A., Trounson, A. O., Anderson, S. A., Stanley, E. & Elefanty, A., 2011, In : Stem Cells. 29, 3, p. 462 - 473 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity

Pereira, L. A., Wong, M., Lim, S. M., Sides, A. E., Stanley, E. G. & Elefanty, A. G., 2011, In : PLoS ONE. 6, 12, 13 p., e28394.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

NKX2-5eGFP/w hESCs for isolation of human cardiac progenitors and cardiomyocytes

Elliott, D. A., Braam, S. R., Koutsis, K., S Ng, E., Jenny, R., Lagerqvist, E. L., Biben, C., Hatzistavrou, T., Hirst, C. E., Yu, Q. C., Skelton, R. JP., Ward-van Oostwaard, D., Lim, S. M., Khammy, O., Li, X., Hawes, S. M., Davis, R. P., Goulburn, A. L., Passier, R., Prall, O. WJ. & 6 othersHaynes, J. M., Pouton, C. W., Kaye, D. M., Mummery, C. L., Elefanty, A. G. & Stanley, E., 2011, In : Nature Methods. 8, 12, p. 1037 - 1040 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2010

Expression from a betageo gene trap in the Slain1 gene locus is predominantly associated with the developing nervous system

Hirst, C. E., Lim, S. M., Pereira, L. A., Mayberry, R. A., Stanley, E. G. & Elefanty, A. G., 2010, In : International Journal of Developmental Biology. 54, 8-9, p. 1383 - 1388 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2009

Enforced expression of mixll during mouse ES cell differentiation suppresses hematopoietic mesoderm and promotes endoderm formation

Lim, S. M., Pereira, L. A., Wong, M. S., Hirst, C. E., Van Vranken, B. E., Pick, M., Trounson, A. O., Elefanty, A. G. & Stanley, E., 2009, In : Stem Cells. 27, p. 363 - 374 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2007

A method for genetic modification of human embryonic stem cells using electroporation

Costa, M., Dottori, M., Sourris, K., Jamshidi, P., Hatzistavrou, T., Davis, R. P. F., Azzola, L., Jackson, S., Lim, S. M., Pera, M. F., Elefanty, A. G. & Stanley, E., 2007, In : Nature Protocols. 2, 4, p. 792 - 796 5 p.

Research output: Contribution to journalArticleResearchpeer-review