Projects per year
Search results
-
Finished
A Randomized Phase 2a, Multicenter, Open-Label, Multiple-Cohort Study Evaluating Regimens Containing Vebicorvir in Subjects with Chronic Hepatitis B Virus Infection
Roberts, S., Matthews, G. V., Sasadeusz, J., Chen, F., Valaydon, Z. S., George, J., MacQuillan, G., Thompson, A. J. & Davison, S.
12/05/21 → 31/12/22
Project: Research
-
A randomized, double-blind, dose-ranging, placebo-controlled, Phase 2a evaluation of the safety, tolerability, and pharmacokinetics of PLN 74809 in participants with primary sclerosing cholangitis (PSC) and suspected liver fibrosis (INTEGRIS-PSC).
Roberts, S., Adams, L. A., George, J., Strasser, S. I., Thompson, A. J. & Lynch, K. D.
1/10/20 → 1/11/23
Project: Research
-
A Phase 2a, Multicenter, Single-Blind, Placebo-Controlled, Multiple Cohort Study Evaluating ABI-H2158-Containing Regimens in Chronic Hepatitis B Infection.
Roberts, S. & Mitchell, J. L.
15/08/20 → 15/08/22
Project: Research
-
A Phase 3 Multicenter, Randomized, Double-blinded, Active-controlled, Clinical Study to Evaluate the Safety and Efficacy of Lenvatinib (E7080/MK-7902) with Pembrolizumab (MK-3475) in Combination with Transarterial Chemoembolization (TACE) Versus TACE in Participants with Incurable/Non-metastatic Hepatocellular Carcinoma (LEAP-012).
Roberts, S. & Lewis, P.
5/06/20 → 31/12/23
Project: Research
-
A Phase 3 Double-blinded, Two-arm Study to Evaluate the Safety and Efficacy of Pembrolizumab (MK-3475) versus Placebo as Adjuvant Therapy in Participants with Hepatocellular Carcinoma and Complete Radiological Response after Surgical Resection or Local Ablation
Roberts, S. & Lewis, P.
8/11/19 → 30/06/23
Project: Research
-
A Randomized, Multi-center, Phase 3 Study of Nivolumab in Combination with Ipilimumab Compared to Sorafenib or Lenvatinib as First-Line Treatment in Participants with Advanced Hepatocellular Carcinoma.
Roberts, S., Lewis, P., George, J., Zekry, A., O’Beirne, J., Tse, E., McLachlan, S. A., Eastgate, M., Ananda, S. S. & Davison, S.
24/09/19 → 30/09/23
Project: Research
-
A Phase 1 Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of Single and Multiple Doses of ABI-H2158 in Healthy Volunteers; and the Multiple-Ascending Dose Pharmacokinetics and Pharmacodynamics in Patients with Chronic Hepatitis B Infection.
Roberts, S. & Mitchell, J. L.
29/05/19 → 30/09/19
Project: Research
-
A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study of Durvalumab Monotherapy or in Combination with Bevacizumab as Adjuvant Therapy in Patients with Hepatocellular Carcinoma who are at High Risk of Recurrence After Curative Hepatic Resection or Ablation (EMERALD-2).
17/05/19 → 31/05/23
Project: Research
-
An Open-Label Study to Assess The Efficacy and Safety of LM011 In Subjects Diagnosed With Non-Alcoholic Steatohepatitis (NASH).
16/04/19 → 31/12/19
Project: Research
-
A Phase III, Randomized, Double-blind, Placebo-controlled, Multicenter Study of Transarterial Chemoembolization (TACE) in Combination with either Durvalumab Monotherapy or Durvalumab plus Bevacizumab Therapy in Patients with Locoregional Hepatocellular Carcinoma (EMERALD-1).
Roberts, S. & Lewis, P.
24/01/19 → 30/04/23
Project: Research