20152020

Research output per year

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Research Output

Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease

Mileto, S. J., Jardé, T., Childress, K. O., Jensen, J. L., Rogers, A. P., Kerr, G., Hutton, M. L., Sheedlo, M. J., Bloch, S. C., Shupe, J. A., Horvay, K., Flores, T., Engel, R., Wilkins, S., McMurrick, P. J., Lacy, D. B., Abud, H. E. & Lyras, D., 7 Apr 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 14, p. 8064-8073 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Clostridium difficile toxins induce VEGF-A and vascular permeability to promote disease pathogenesis

Huang, J., Kelly, C. P., Bakirtzi, K., Villafuerte Gálvez, J. A., Lyras, D., Mileto, S. J., Larcombe, S., Xu, H., Yang, X., Shields, K. S., Zhu, W., Zhang, Y., Goldsmith, J. D., Patel, I. J., Hansen, J., Huang, M., Ylä-Herttuala, S., Moss, A. C., Paredes-Sabja, D., Pothoulakis, C. & 3 others, Shah, Y. M., Wang, J. & Cheng, X., Feb 2019, In : Nature Microbiology. 4, 11 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Enterotoxic clostridia: Clostridioides difficile infections

Mileto, S., Das, A. & Lyras, D., 24 May 2019, In : Microbiology Spectrum. 7, 3, 26 p., GPP3-0015-2018.

Research output: Contribution to journalArticleOtherpeer-review

1 Citation (Scopus)

In silico, in vitro and in vivo analysis of putative virulence factors identified in large clostridial toxin-negative, binary toxin- producing C. difficile strains

Androga, G. O., Knight, D. R., Hutton, M. L., Mileto, S. J., James, M. L., Evans, C., Lyras, D., Chang, B. J., Foster, N. F. & Riley, T. V., Dec 2019, In : Anaerobe. 60, 8 p., 102083.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Defining the roles of TcdA and TcdB in localized gastrointestinal disease, systemic organ damage, and the host response during clostridium difficile Infections

Carter, G. P., Chakravorty, A., Nguyen, T. A. P., Mileto, S., Schreiber, F., Li, L., Howarth, P., Clare, S., Cunningham, B., Sambol, S. P., Cheknis, A. K., Figueroa, I., Johnson, S., Gerding, D., Rood, J. I., Dougan, G., Lawley, T. D. & Lyras, D., 2015, In : mBio. 6, 3, p. 1 - 10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
109 Citations (Scopus)