1980 …2021

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Personal profile

Biography

Head of the Immune and Cancer Cell Signalling Laboratory

The Nuclear Factor of kappa B (NF-KB) signal transduction pathway plays a key role in the immune system and features prominently in disease-associated pathology. Our group focuses on the use of genetically modified mice to understand how NF-KB regulates normal development, differentiation and cellular functions particularly in the immune system, as well as its roles in autoimmune disease and cancer. The long-term goal of our research is to identify ways of manipulating NF-KB transcription factor activities for therapeutic purposes.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research area keywords

  • NF-kappaB
  • transcription
  • signal transduction
  • immunity
  • inflammation
  • autoimmunity
  • cancer

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