1980 …2018

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Personal profile

Biography

Head of the Immune and Cancer Cell Signalling Laboratory

The Nuclear Factor of kappa B (NF-KB) signal transduction pathway plays a key role in the immune system and features prominently in disease-associated pathology. Our group focuses on the use of genetically modified mice to understand how NF-KB regulates normal development, differentiation and cellular functions particularly in the immune system, as well as its roles in autoimmune disease and cancer. The long-term goal of our research is to identify ways of manipulating NF-KB transcription factor activities for therapeutic purposes.

Research area keywords

  • NF-kappaB
  • transcription
  • signal transduction
  • immunity
  • inflammation
  • autoimmunity
  • cancer

Network

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