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Personal profile


Stephen Opat is the director of Clinical Haematology at Monash Health, a dynamic academic research organization that integrates the best evidence–base into routine patient care. It provides haematology care to a population of approximately 1.3 million, making it one of the largest services in Australia.  Key leadership areas in clinical care and research include: Lymphoid cancer, chronic myeloid disorders, thromboembolic disease, haemoglobinopathy and transfusion medicine. It is an active member of a number of research organisations including the Monash Health Translation Precinct (MHTP), the Centre for Cancer Research (CCR) at the Hudson Institute of Medical Research, and the Australasian Leukaemia and Lymphoma Group. His particular interests include the diagnosis and management of lymphoma and chronic lymphocytic leukaemia, cancer genomics, disorders of iron metabolism, Gaucher disease and novel therapies. He is the principal investigator in over 30 clinical trials mainly in lymphoid cancer and founder of the Australasian Lymphoma and Related Diseases Registry. He has a strong interest in medical education, particularly in developing countries, and has lectured widely throughout the Asia-Pacific. He is extremely active in the Haematology Society of Australia and New Zealand where he currently serves as President.


  • Lymphoma
  • Genomics
  • Chronic Lymphocytic Leukaemia
  • Cancer Immunology
  • Cancer Cell Biology

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Projects 2010 2019

AbbVie Lymphoma Registry support

Wood, E. M., Opat, S., McQuilten, Z., Waters, N. & Rowsell, L.


Project: Research

LaRDR: Lymphoma and Related Diseases Registry

Wood, E. M., McQuilten, Z., Waters, N. & Opat, S.


Project: Research

LaRDR: Lymphoma and Related Diseases Registry

Wood, E. M., McQuilten, Z., Opat, S. & Waters, N.


Project: Research

Chronic Lymphocytic Leukaemia Registry

Wood, E. M., McQuilten, Z., Opat, S., Waters, N. & Rowsell, L.


Project: Research

Research Output 2007 2018

Adaptive reprogramming of NK cells in X-Linked lymphoproliferative syndrome

Opat, S., Hearps, A. C., Thia, K., Yuen, A., Rogers, B., Chachage, M., Moore, G., Shortt, J., Ryland, G., Blombery, P., Schwarer, A. P., Noori, T., Trapani, J. A., Jaworowski, A. & Voskoboinik, I. 8 Feb 2018 In : Blood. 131, 6, p. 699-702 4 p.

Research output: Contribution to journalLetter

High-dose therapy and autologous stem cell transplantation may only be applicable to selected patients with secondary CNS diffuse large B-cell lymphoma

Cheah, C. Y., Joske, D., Cull, G., Gilbertson, M., Opat, S. S., Tam, C. S., Wirth, A. & Seymour, J. F. Sep 2017 In : British Journal of Haematology. 178, 6, p. 991-994 3 p.

Research output: Contribution to journalArticle

Infection is an Independent Predictor of Death in Diffuse Large B Cell Lymphoma

Dendle, C., Gilbertson, M., Spelman, T., Stuart, R. L., Korman, T. M., Thursky, K., Opat, S. & McQuilten, Z. 30 Jun 2017 In : Scientific Reports. 7, 1, 10 p., 4395

Research output: Contribution to journalArticle

Open Access

Management of patients with previously untreated chronic lymphocytic leukaemia with obinutuzumab and chlorambucil

Tam, C. S., Kuss, B., Opat, S., Boulos, J. & Marlton, P. 1 Jul 2017 In : Internal Medicine Journal. 47, Suppl 4, p. 5-10 6 p.

Research output: Contribution to journalReview Article

Timely initiation of chemotherapy: a systematic literature review of six priority cancers – results and recommendations for clinical practice

Alexander, M., Blum, R., Burbury, K., Coutsouvelis, J., Dooley, M., Fazil, O., Griffiths, T., Ismail, H., Joshi, S. P., Love, N., Opat, S., Parente, P., Porter, N., Ross, E., Siderov, J., Thomas, P., White, S. C., Kirsa, S. & Rischin, D. 1 Jan 2017 In : Internal Medicine Journal. 47, 1, p. 16-34 19 p.

Research output: Contribution to journalReview Article