Projects per year
Personal profile
Biography
Prof Stephen Nicholls is a world-renowned cardiologist, and leads the Victorian Heart Hospital (VHH). A multiple-award winner, Professor Nicholls has written more than 770 manuscripts, book chapters and conference proceedings, and has raised more than $100 million in research funding.
Since 2012, Prof Nicholls has been Deputy Director and Heart Health Theme Leader at the South Australian Health and Medical Research Institute (SAHMRI). He is also Professor of Cardiology at the University of Adelaide, Consultant Cardiologist at the Royal Adelaide Hospital and Principal Research Fellow of the National Health and Medical Research Council of Australia (NHMRC).
Prof Nicholls’s research broadly focuses on developing new strategies to reduce the risk of heart disease, involving translational research spanning preclinical human and clinical trials.
External positions
Director of MonashHeart, MonashHeart
8 Oct 2018 → …
South Australian Health and Medical Research Institute Limited (SAHMRI)
University of Adelaide
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 5 Gender Equality -
SDG 11 Sustainable Cities and Communities
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Leveraging mammograms to screen for cardiovascular disease
Nerlekar, N. (Primary Chief Investigator (PCI)), Davis, E. (Chief Investigator (CI)), Evans, J. (Chief Investigator (CI)), Ooi, C. (Chief Investigator (CI)), Marwick, T. H. (Chief Investigator (CI)), Nicholls, S. (Chief Investigator (CI)), Machado, R. (Associate Investigator (AI)), Soh, C. (Associate Investigator (AI)), Gao, L. (Associate Investigator (AI)), Ragonnet, N. (Associate Investigator (AI)), Whitmore , K. (Associate Investigator (AI)) & Nicholls, S. (Chief Investigator (CI))
22/06/26 → 21/06/28
Project: Research
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A Phase 3 Open-Label Extension Study to Evaluate the Long-Term Safety and Efficacy of Plozasiran in Adults with Hypertriglyceridemia (SHASTA-10 Study)
Nicholls, S. (Primary Chief Investigator (PCI))
1/04/26 → 1/04/27
Project: Research
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Implementation of state-based cascade testing centres for autosomal dominant conditions using familial hypercholesterolaemia as the exemplar
Sarkies, M. N. (Primary Chief Investigator (PCI)), Watts, G. F. (Chief Investigator (CI)), Sullivan, D. R. (Chief Investigator (CI)), Black, A. (Chief Investigator (CI)), Hespe, C. M. (Chief Investigator (CI)), Srinivasan, S. (Chief Investigator (CI)), Martin, A. C. (Chief Investigator (CI)), Bell, D. (Chief Investigator (CI)), Pang, J. (Chief Investigator (CI)), Garton-Smith, J. (Chief Investigator (CI)), Ademi Delaney, Z. (Chief Investigator (CI)), Tiller, J. (Chief Investigator (CI)), Hyun, K. K. (Chief Investigator (CI)), Page, M. R. (Chief Investigator (CI)), Trent, R. J. (Chief Investigator (CI)), Della-Vedova, J. (Associate Investigator (AI)), Hendricks, C. (Associate Investigator (AI)), Li, S. (Associate Investigator (AI)), Ingles, J. (Associate Investigator (AI)), Kostner, K. M. (Associate Investigator (AI)), Braithwaite, J. (Associate Investigator (AI)), Horton, A. (Associate Investigator (AI)), Nicholls, S. (Associate Investigator (AI)), Burns, B. (Associate Investigator (AI)) & Clifton, P. M. (Associate Investigator (AI))
1/03/26 → 29/02/28
Project: Research
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A Double-blind, Randomized, Placebo-controlled, Multi-center Study Evaluating the Safety, Tolerability, and Effect of Olpasiran on Coronary Artery Plaque Burden Assessed by Coronary Computed Tomography Angiography in Participants With Stable Atherosclerotic Cardiovascular Disease and Elevated Lipoprotein(a)
Nicholls, S. (Primary Chief Investigator (PCI))
23/02/26 → 31/12/27
Project: Research
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REFORM CVD: Re-Focusing on Obesity as a Risk Factor to Manage in Cardiovascular Disease - Phase2: Stakeholder understanding
Nicholls, S. (Primary Chief Investigator (PCI))
1/11/25 → 31/12/26
Project: Research
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Author Correction: Obicetrapib in patients with heterozygous familial hypercholesterolemia: the BROOKLYN randomized clinical trial (Nature Medicine, (2026), 32, 3, (1052-1060), 10.1038/s41591-025-04179-4)
Nicholls, S. J., Nelson, A. J., Ditmarsch, M., Kastelein, J. J. P., Ballantyne, C. M., Ray, K. K., Navar, A. M., Nissen, S. E., Goldberg, A. C., Brunham, L. R., Wuerdeman, E., Neild, A. L., Kling, D., Hsieh, A., Butters, J., Ference, B. A., Laufs, U., Banach, M., Mehran, R. & Catapano, A. L. & 3 others, , May 2026, In: Nature Medicine. 32, 5, 1 p., 1935.Research output: Contribution to journal › Comment / Debate › Other › peer-review
Open Access1 Link opens in a new tab Citation (Scopus) -
Cardiovascular Outcomes with Tirzepatide in Type 2 Diabetes. Reply
Nicholls, S. J., Pavo, I. & D'Alessio, D., 16 Apr 2026, In: The New England Journal of Medicine. 394, 15, 2 p.Research output: Contribution to journal › Letter › Other › peer-review
1 Link opens in a new tab Citation (Scopus) -
Clonal hematopoiesis of indeterminate potential (CHIP): A need for standardized definition and criteria for translational research studies
Harraka, P., Yeh, P., Nicholls, S. J. & Southey, M. C., Apr 2026, In: Genetics in Medicine. 28, 4, 4 p., 102530.Research output: Contribution to journal › Comment / Debate › Other › peer-review
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Corrigendum to: “Australian Atherosclerosis Society Position Statement on Lipoprotein(a): Clinical and Implementation Recommendations” [Heart Lung Circ. 32(3) (2023) 287–296., (S1443950622012318), (10.1016/j.hlc.2022.11.015)]
Ward, N. C., Watts, G. F., Bishop, W., Colquhoun, D., Hamilton-Craig, C., Hare, D. L., Kangaharan, N., Kostner, K. M., Kritharides, L., O'Brien, R., Mori, T. A., Nestel, P. J., Nicholls, S. J., Psaltis, P. J., Raffoul, N., White, H. D. & Sullivan, D. R., Jan 2026, In: Heart Lung and Circulation. 35, 1, p. e15 1 p.Research output: Contribution to journal › Comment / Debate › Other › peer-review
Open Access -
Erratum: Correction to: "Patient-Specific Myocardial Infarction Risk Thresholds From AI-Enabled Coronary Plaque Analysis" (Circulation. Cardiovascular imaging (2024) 17 10 DOI: 10.1161/CIRCIMAGING.124.016958.)
Miller, R. J. H., Manral, N., Lin, A., Shanbhag, A., Park, C., Kwiecinski, J., Killekar, A., McElhinney, P., Matsumoto, H., Razipour, A., Grodecki, K., Kwan, A. C., Han, D., Kuronuma, K., Flores Tomasino, G., Geers, J., Goeller, M., Marwan, M., Gransar, H. & Tamarappoo, B. K. & 13 others, , Jul 2026, In: Circulation: Cardiovascular Imaging. 19, 7, 1 p., e000092.Research output: Contribution to journal › Comment / Debate › Other › peer-review