1984 …2021

Research output per year

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Article
1984

Differential effects of steroids on leukocyte-mediated glomerulonephritis in the rabbit

Holdsworth, S. R. & Bellomo, R., 1 Jan 1984, In : Kidney International. 26, 2, p. 162-169 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
17 Citations (Scopus)
1985

Wegener's Granulomatosis: Clinical features and outcome in seventeen patients

LITTLEJOHN, G. O., RYAN, P. J. & HOLDSWORTH, S. R., 1 Jan 1985, In : Australian and New Zealand Journal of Medicine. 15, 2, p. 241-245 5 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)
1987

Comparison of immunofluorescence and immunoperoxidase for demonstration of antinuclear antibodies on HEp-2 substrate

Tipping, P. G., Dimech, W. J., Littlejohn, G. O. & Holdsworth, S. R., 1 Jun 1987, In : Rheumatology. 26, 3, p. 188-192 5 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)
1988

Detection of anti-dna antibodies: A comparison between two farr assays, Crithidia luciliae and a human chromosomal substrate assay

Tipping, P. G., Buchanan, R. R. C., Riglar, A. G., Dimech, W. J., Littlejohn, G. O. & Holdsworth, S. R., 1 Jun 1988, In : Rheumatology. 27, 3, p. 206-210 5 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)
1991

Measurement of anti-DNA antibodies by elisa: A comparative study with crithidia and a farr assay

Tipping, P. G., Buchanan, R. C., Riglar, A. G., Dimech, W. J., Littlejohn, G. O. & Holdsworth, S. R., 1 Jan 1991, In : Pathology. 23, 1, p. 21-24 4 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)
1995

Detection of intracellular lipocortin 1 in human leukocyte subsets

Morand, E. F., Hutchinson, P., Hargreaves, A., Goulding, N. J., Boyce, N. W. & Holdsworth, S. R., 1 Jan 1995, In : Clinical Immunology and Immunopathology. 76, 2, p. 195-202 8 p.

Research output: Contribution to journalArticleResearchpeer-review

62 Citations (Scopus)
1997

Antibody independent crescentic glomerulonephritis in m chain deficient mice

Shuo, L., Holdsworth, S. R. & Tipping, P. G., 1997, In : Kidney International. p. 672 - 678 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Antiinflammatory effect of lipocortin 1 in experimental arthritis

Yang, Y., Leech, M., Hutchinson, P., Holdsworth, S. R. & Morand, E. F., 1997, In : Inflammation. p. 583 - 596 13 p.

Research output: Contribution to journalArticleResearchpeer-review

52 Citations (Scopus)

Anti-neutrophil monoclonal antibody therapy inhibits the development of adjuvant arthritis

Santos, L., Morand, E. F., Boyce, N. W. & Holdsworth, S. R., 1997, In : Clinical and Experimental Immunology. p. 248 - 253 6 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

Immune modulation with interleukin-4 and interleukin-10 prevents crescent formation and glomerular injury in experimental glomerulonephritis

Tipping, P. G., Kitching, A. R., Huang, X. R., Mutch, D. A. & Holdsworth, S. R., 1997, In : European Journal of Immunology. p. 530 - 537 8 p.

Research output: Contribution to journalArticleResearchpeer-review

115 Citations (Scopus)

Interleukin-4 and interleukin-10 attenuate established crescentic glomerulonephritis in mice

Kitching, A. R., Tipping, P. G., Huang, X. R., Mutch, D. A. & Holdsworth, S. R., 1997, In : Kidney International. p. 52 - 59 8 p.

Research output: Contribution to journalArticleResearchpeer-review

75 Citations (Scopus)

Mechanisms of T cell-induced glomerular injury in anti-glomerular basement membrane (GBM) glomerulonephritis in rats

Huang, X. R., Tipping, P. G., Apostolopoulos, J., Oettinger, C., D'Souza, M., Milton, G. & Holdsworth, S. R., 1997, In : Clinical and Experimental Immunology. p. 134 - 142 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Plasminogen and Plasminogen Activators Protect against Renal Injury in Crescentic Glomerulonephritis

Kitching, A. R., Holdsworth, S. R., Ploplis, V., Plow, E., Collen, D., Carmeliet, P. & Tipping, P. G., 1997, In : The Journal of Experimental Medicine. p. 963 - 968 6 p.

Research output: Contribution to journalArticleResearchpeer-review

152 Citations (Scopus)

Suppression of adjuvant arthritis and synovial macrophage inducible nitric oxide by N-iminoethyl-L ornithine, a nitric oxide synthase inhibitor

Santos, L., Morand, E. F., Yang, Y., Hutchinson, P. & Holdsworth, S. R., 1997, In : Inflammation. p. 299 - 311 13 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Th1 responsiveness to nephritogenic antigens determines susceptibility to crescentic glomerulonephritis in mice

Huang, X. R., Tipping, P. G., Shuo, L. & Holdsworth, S. R., 1997, In : Kidney International. p. 94 - 103 10 p.

Research output: Contribution to journalArticleResearchpeer-review

145 Citations (Scopus)

Th2 Responses Induce Humorally Mediated Injury in Experimental Anti-Glomerular Membrane Glomerulonephritis

Huang, X. R., Holdsworth, S. R. & Tipping, P. G., 1997, In : Journal of the American Society of Nephrology. p. 1101 - 1108 8 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)
1998
28 Citations (Scopus)

Interleukin-4 deficiency enhances Th1 responses and crescentic glomerulonephritis in mice

Kitching, A. R., Tipping, P. G., Mutch, D. A., Huang, X. R. & Holdsworth, S. R., 1998, In : Kidney International. p. 112 - 118 7 p.

Research output: Contribution to journalArticleResearchpeer-review

61 Citations (Scopus)

Involvement of Macrophage Migration Inhibitory Factor In The Evolution of Rat Adjuvant Arthritis

Leech, M., Metz, C. N., Santos, L., Peng, T., Holdsworth, S. R., Bucala, R. & Morand, E. F., 1998, In : Arthritis and Rheumatism. 41, 5, p. 910 - 917 8 p.

Research output: Contribution to journalArticleResearchpeer-review

147 Citations (Scopus)

Platelet Fatty Acids and Peripheral Blood Lymphocyte Subsets in an Institutionalized Elderly Population

Lukito, W., Hodgson, J. M., Hutchinson, P., Wahlqvist, M. L., Holdsworth, S. R., Savige, G. S. & Wattanapenpaiboon, N. T., 1998, In : Cytometry. p. 17 - 21 5 p.

Research output: Contribution to journalArticleResearchpeer-review

P-selectin requirement for neutrophil accumulation and injury in the direct passive Arthus reaction

Santos, L., Huang, X. R., Berndt, M. C. & Holdsworth, S. R., 1998, In : Clinical and Experimental Immunology. p. 281 - 286 6 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Stimulation of PAI-1 in rabbit anti-GBM glomerulonephritis

Gallicchio, M., McFarlane, J. R., Hufnagl, P., Holdsworth, S. R. & Tipping, P. G., 1998, In : Nephrology. p. 65 - 74 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

T cells direct macrophage recruitment and giant cell formation but not proliferation in experimental crescentic glomerulonephritis

Huang, X. R., Tipping, P. G. & Holdsworth, S. R., 1998, In : Nephrology. p. 151 - 156 6 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

IFN-γ mediates crescent formation and cell-mediated immune injury in murine glomerulonephritis

Kitching, A. R., Holdsworth, S. R. & Tipping, P. G., 1 Apr 1999, In : Journal of the American Society of Nephrology. 10, 4, p. 752-759 8 p.

Research output: Contribution to journalArticleResearchpeer-review

114 Citations (Scopus)
70 Citations (Scopus)

Immunopathogenesis of crescentic glomerulonephritis

Tipping, P. G., Kitching, A. R., Cunningham, M. A. & Holdsworth, S. R., 1999, In : Current Opinion in Nephrology and Hypertension. p. 281 - 286 6 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Macrophage Migration Inhibitory Factor In Rheumatoid Arthritis - Evidence of Proinflammatory Function and Regulation by Glucocorticoids

Leech, M., Metz, C. N., Hall, P., Hutchinson, P., Gianis, K., Smith, M., Weedon, H., Holdsworth, S. R., Bucala, R. & Morand, E. F., 1999, In : Arthritis and Rheumatism. p. 1601 - 1608 8 p.

Research output: Contribution to journalArticleResearchpeer-review

271 Citations (Scopus)

Prominence of Cell-Mediated Immunity Effectors in "Pauci-Immune" Glomerulonephritis

Cunningham, M. A., Huang, X. R., Dowling, J. P., Tipping, P. G. & Holdsworth, S. R., 1999, In : Journal of the American Society of Nephrology. p. 499 - 506 8 p.

Research output: Contribution to journalArticleResearchpeer-review

126 Citations (Scopus)

Th1 and th2 T helper cell subsets affect patterns of injury and outcomes in glomerulonephritis

Holdsworth, S. R., Kitching, A. R. & Tipping, P. G., 1 Jan 1999, In : Kidney International. 55, 4, p. 1198-1216 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
204 Citations (Scopus)

Tissue factor pathway inhibitor expression in human crescentic glomerulonephritis

Cunningham, M. A., Ono, T., Hewitson, T. D., Tipping, P. G., Becker, G. J. & Holdsworth, S. R., 1999, In : Kidney International. p. 1311 - 1318 8 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)
2000

Chemokines as therapeutic targets in renal disease

Holdsworth, S. R., Kitching, A. R. & Tipping, P. G., 2000, In : Current Opinion in Nephrology and Hypertension. p. 505 - 511 7 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Crescentic glomerulonephritis - a manifestation of a nephritogenic Th1 response?

Kitching, A. R., Holdsworth, S. R. & Tipping, P. G., 2000, In : Histology and Histopathology. p. 993 - 1003 11 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

Endogenous glucocorticoids modulate experimental anti-glomerular basement membrane glomerulonephritis

Leech, M., Huang, X. R. R., Morand, E. F. & Holdsworth, S. R., 2000, In : Clinical and Experimental Immunology. p. 161 - 168 8 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Endogenous interleukin-10 regulates Th1 responses that induce crescentic glomerulonephritis

Kitching, A. R., Tipping, P. G., Timoshanko, J. R. & Holdsworth, S. R., 2000, In : Kidney International. p. 518 - 525 8 p.

Research output: Contribution to journalArticleResearchpeer-review

69 Citations (Scopus)

IL-18 Has IL-12-Independent Effects in Delayed-Type Hypersensitivity: Studies in Cell-Mediated Crescentic Glomerulonephritis

Kitching, A. R., Tipping, P. G., Kurimoto, M. & Holdsworth, S. R., 2000, In : Journal of Immunology. p. 4649 - 4657 9 p.

Research output: Contribution to journalArticleResearchpeer-review

43 Citations (Scopus)

Interleukin-10 Inhibits Macrophage-Induced Glomerular Injury

Huang, X. R. R., Kitching, A. R., Tipping, P. G. & Holdsworth, S. R., 2000, In : Journal of the American Society of Nephrology. p. 262 - 269 8 p.

Research output: Contribution to journalArticleResearchpeer-review

47 Citations (Scopus)

MHC class I pathway is not required for the development of crescentic glomerulonephritis in mice

Li, S., Holdsworth, S. R. & Tipping, P. G., 2000, In : Clinical and Experimental Immunology. p. 453 - 458 6 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Protease-activated Receptor 1 Mediates Thrombin-dependent, Cell-mediated Renal Inflammation in Crescentic Glomerulonephritis

Cunningham, M. A., Rondeau, E., Chen, X., Coughlin, S. R., Holdsworth, S. R. & Tipping, P. G., 2000, In : The Journal of Experimental Medicine. p. 455 - 461 7 p.

Research output: Contribution to journalArticleResearchpeer-review

161 Citations (Scopus)
2001

Interleukin-12 from intrinsic cells is an effector of renal injury in crescentic glomerulonephritis

Timoshanko, J. R., Kitching, A. R., Holdsworth, S. R. & Tipping, P. G., 2001, In : Journal of the American Society of Nephrology. 12, p. 464 - 471 8 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

Microbiologic profile in bronchiectasis

King, P. T., Johnson, P., Freezer, N. J., Holdsworth, S. R. & Holmes, P. W., 1 Dec 2001, In : Respirology. 6, SUPPL. 1

Research output: Contribution to journalArticleResearchpeer-review

2002

effects of CRLA4-Fc on glomerular injury in humorally-mediated glomerulonephritis in BALB/c mice

Kitching, A. R., Huang, X. R., Tipping, P. G. & Holdsworth, S. R., 2002, In : Clinical and Experimental Immunology. 128, p. 429 - 435 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Effects of CTLA4-Fc on glomerular injury in humorally-mediated glomerulonephritis in BALB/c mice

Kitching, A. R., Huang, X. R., Ruth, A. J., Tipping, P. G. & Holdsworth, S. R., 26 Jun 2002, In : Clinical and Experimental Immunology. 128, 3, p. 429-435 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
6 Citations (Scopus)

IFN-g Production by Intrinsic Renal Cells and Bone Marrow-Derived Cells is Required for Full Expression of Crescentic Glomerulonephritis in Mice

Timoshanko, J. R., Holdsworth, S. R., Kitching, A. R. & Tipping, P. G., 2002, In : Journal of Immunology. 168, p. 4135 - 4141 7 p.

Research output: Contribution to journalArticleResearchpeer-review

IFN-γ production by intrinsic renal cells and bone marrow-derived cells is required for full expression of crescentic glomerulonephritis in mice

Timoshanko, J. R., Holdsworth, S. R., Kitching, A. R. & Tipping, P. G., 15 Apr 2002, In : Journal of Immunology. 168, 8, p. 4135-4141 7 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

Interleukin-10 inhibits experimental mesangial proliferative glomerulonephritis

Kitching, A. R., Katerelos, M., Mudge, S. J., Tipping, P. G., Power, D. A. & Holdsworth, S. R., 2002, In : Clinical and Experimental Immunology. 128, 1, p. 36 - 43 8 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

The Requirement for Granulocyte-Macrophage Colony-Stimulating Factor and Granulocyte Colony-Stimulating Factor in Leukocyte-Mediated Immune Glomerular Injury

Kitching, A. R., Huang, X. R., Turner, A. L., Tipping, P. G., Dunn, A. R. & Holdsworth, S. R., 2002, In : Journal of the American Society of Nephrology. 13, 2, p. 350 - 358 9 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)
2003

Adaptive immunity to nontypeable Haemophilus influenzae.

King, P. T., Hutchinson, P. E., Johnson, P. D., Holmes, P. W., Freezer, N. J. & Holdsworth, S. R., 1 Jan 2003, In : American Journal of Respiratory and Critical Care Medicine. 167, 4, p. 587-592 6 p.

Research output: Contribution to journalArticleResearchpeer-review

80 Citations (Scopus)

Intrinsic renal cell expression of CD40 directs Th1 effectors inducing experimental crescentic glomerulonephritis

Ruth, A-J., Kitching, A. R., Semple, T. J., Tipping, P. G. & Holdsworth, S. R., 2003, In : Journal of the American Society of Nephrology. 14, 11, p. 2813 - 2822 10 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)