Projects per year
Personal profile
Biography
Viruses are part of day-to-day encounters that the immune system needs to deal with. How the immune system recognises and eliminates viral infection is not fully understood. Indeed, viruses are able to mutate in order to escape the immune system surveillance. If we were to develop better vaccine and drugs, or even vaccine against viruses like HIV, it is essential to understand the mechanism of viral recognition and viral escape prior to this.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Immunology
- HLA
- T cell receptors
- influenza
- HIV
Network
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Defining SARS-CoV-2 immune maintenance in the Australian population
Smith, C., Gras, S., Short, K. R., Jacobson, K., Hartel, G. F., Barrett, H. & Kitchener, S.
Department of Health (Australia)
1/11/20 → 1/11/22
Project: Research
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Beckman Coulter Optima Analytical Ultracentrifuge (AUC)
Dunstone, M., Whisstock, J., Daly, R., Atkinson, S., Turner, S., Lithgow, T., Gras, S., Stone, M., Davidovich, C., Rood, J., Coulibaly, F., Wilce, J., Borg, N., McGowan, S., Buckle, A., Elmlund, D., Elmlund, H., Belousoff, M., Ellisdon, A., Law, R., Purcell, A., Cryle, M., Nold, M., Nold, C., Warr, C., Johnson, T., Henstridge, M., Aguilar, M., Stroud, D. & Ryan, M.
1/12/16 → 31/12/17
Project: Research
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Canonical T cell receptor docking on peptide–MHC is essential for T cell signaling
Zareie, P., Szeto, C., Farenc, C., Gunasinghe, S. D., Kolawole, E. M., Nguyen, A., Blyth, C., Sng, X. Y. X., Li, J., Jones, C. M., Fulcher, A. J., Jacobs, J. R., Wei, Q., Wojciech, L., Petersen, J., Gascoigne, N. R. J., Evavold, B. D., Gaus, K., Gras, S., Rossjohn, J. & 1 others, , 4 Jun 2021, In: Science. 372, 6546, 14 p., eabe9124.Research output: Contribution to journal › Article › Research › peer-review
7 Citations (Scopus) -
CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph
Hensen, L., Illing, P. T., Bridie Clemens, E., Nguyen, T. H. O., Koutsakos, M., van de Sandt, C. E., Mifsud, N. A., Nguyen, A. T., Szeto, C., Chua, B. Y., Halim, H., Rizzetto, S., Luciani, F., Loh, L., Grant, E. J., Saunders, P. M., Brooks, A. G., Rockman, S., Kotsimbos, T. C., Cheng, A. C. & 16 others, , 18 May 2021, In: Nature Communications. 12, 1, 20 p., 2931.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients
Nguyen, T. H. O., Koutsakos, M., van de Sandt, C. E., Crawford, J. C., Loh, L., Sant, S., Grzelak, L., Allen, E. K., Brahm, T., Clemens, E. B., Auladell, M., Hensen, L., Wang, Z., Nüssing, S., Jia, X., Günther, P., Wheatley, A. K., Kent, S. J., Aban, M., Deng, Y. M. & 16 others, , Dec 2021, In: Nature Communications. 12, 1, 17 p., 2691.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Citations (Scopus) -
A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice
Valencia-Hernandez, A. M., Ng, W. Y., Ghazanfari, N., Ghilas, S., de Menezes, M. N., Holz, L. E., Huang, C., English, K., Naung, M., Tan, P. S., Tullett, K. M., Steiner, T. M., Enders, M. H., Beattie, L., Chua, Y. C., Jones, C. M., Cozijnsen, A., Mollard, V., Cai, Y., Bowen, D. G. & 15 others, , 10 Jun 2020, In: Cell Host & Microbe. 27, 6, p. 950-962 13 p.Research output: Contribution to journal › Article › Research › peer-review
22 Citations (Scopus) -
A shared TCR bias toward an immunogenic EBV epitope dominates in HLA-B*07: 02-Expressing individuals
Rowntree, L. C., Nguyen, T. H. O., Farenc, C., Halim, H., Hensen, L., Rossjohn, J., Kotsimbos, T. C., Purcell, A. W., Kedzierska, K., Gras, S. & Mifsud, N. A., 15 Sep 2020, In: Journal of Immunology. 205, 6, p. 1524-1534 11 p.Research output: Contribution to journal › Article › Research › peer-review
6 Citations (Scopus)
Prizes
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Dean's Award for Early Career
Gras, Stephanie (Recipient), 2011
Prize: Prize (including medals and awards)
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Georgina Sweet Awards for Women in Quantitative Biomedical Science
Gras, Stephanie (Recipient), 2017
Prize: Prize (including medals and awards)
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Press / Media
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A “super” receptor that helps kill HIV infected cells
Carine Farenc & Stephanie Gras
9/06/18
1 Media contribution
Press/Media: Article/Feature