Projects per year
Personal profile
Biography
Viruses are part of day-to-day encounters that the immune system needs to deal with. How the immune system recognises and eliminates viral infection is not fully understood. Indeed, viruses are able to mutate in order to escape the immune system surveillance. If we were to develop better vaccine and drugs, or even vaccine against viruses like HIV, it is essential to understand the mechanism of viral recognition and viral escape prior to this.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Immunology
- HLA
- T cell receptors
- influenza
- HIV
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 3 Finished
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Defining SARS-CoV-2 immune maintenance in the Australian population
Smith, C., Gras, S., Short, K. R., Jacobson, K., Hartel, G. F., Barrett, H. & Kitchener, S.
Department of Health and Aged Care (Australia)
1/11/20 → 1/11/22
Project: Research
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Beckman Coulter Optima Analytical Ultracentrifuge (AUC)
Dunstone, M., Whisstock, J., Daly, R., Atkinson, S., Turner, S., Lithgow, T., Gras, S., Stone, M., Davidovich, C., Rood, J., Coulibaly, F., Wilce, J., Borg, N., McGowan, S., Buckle, A., Elmlund, D., Elmlund, H., Belousoff, M., Ellisdon, A., Law, R., Purcell, A., Cryle, M., Nold, M., Nold, C., Warr, C., Johnson, T., Henstridge, M., Aguilar, M., Stroud, D. & Ryan, M.
1/12/16 → 31/12/17
Project: Research
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Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus
Szeto, C., Zareie, P., Wirasinha, R. C., Zhang, J. B., Nguyen, A. T., Riboldi-Tunnicliffe, A., La Gruta, N. L., Gras, S. & Daley, S. R., 23 Aug 2022, In: Nature Communications. 13, 1, 12 p., 4951.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
HLA-A∗11:01-restricted CD8+ T cell immunity against influenza A and influenza B viruses in Indigenous and non-Indigenous people
Habel, J. R., Nguyen, A. T., Rowntree, L. C., Szeto, C., Mifsud, N. A., Clemens, E. B., Loh, L., Chen, W., Rockman, S., Nelson, J., Davies, J., Miller, A., Tong, S. Y. C., Rossjohn, J., Gras, S., Purcell, A. W., Hensen, L., Kedzierska, K. & Illing, P. T., Mar 2022, In: PLoS Pathogens. 18, 3, 28 p., e1010337.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
Canonical T cell receptor docking on peptide–MHC is essential for T cell signaling
Zareie, P., Szeto, C., Farenc, C., Gunasinghe, S. D., Kolawole, E. M., Nguyen, A., Blyth, C., Sng, X. Y. X., Li, J., Jones, C. M., Fulcher, A. J., Jacobs, J. R., Wei, Q., Wojciech, L., Petersen, J., Gascoigne, N. R. J., Evavold, B. D., Gaus, K., Gras, S., Rossjohn, J., & 1 others, 4 Jun 2021, In: Science. 372, 6546, 14 p., eabe9124.Research output: Contribution to journal › Article › Research › peer-review
28 Citations (Scopus) -
CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph
Hensen, L., Illing, P. T., Bridie Clemens, E., Nguyen, T. H. O., Koutsakos, M., van de Sandt, C. E., Mifsud, N. A., Nguyen, A. T., Szeto, C., Chua, B. Y., Halim, H., Rizzetto, S., Luciani, F., Loh, L., Grant, E. J., Saunders, P. M., Brooks, A. G., Rockman, S., Kotsimbos, T. C., Cheng, A. C., & 16 others, 18 May 2021, In: Nature Communications. 12, 1, 20 p., 2931.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Citations (Scopus) -
Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients
Nguyen, T. H. O., Koutsakos, M., van de Sandt, C. E., Crawford, J. C., Loh, L., Sant, S., Grzelak, L., Allen, E. K., Brahm, T., Clemens, E. B., Auladell, M., Hensen, L., Wang, Z., Nüssing, S., Jia, X., Günther, P., Wheatley, A. K., Kent, S. J., Aban, M., Deng, Y. M., & 16 others, Dec 2021, In: Nature Communications. 12, 1, 17 p., 2691.Research output: Contribution to journal › Article › Research › peer-review
Open Access18 Citations (Scopus)
Prizes
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Dean's Award for Early Career
Gras, Stephanie (Recipient), 2011
Prize: Prize (including medals and awards)
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Georgina Sweet Awards for Women in Quantitative Biomedical Science
Gras, Stephanie (Recipient), 2017
Prize: Prize (including medals and awards)
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Press/Media
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A “super” receptor that helps kill HIV infected cells
Carine Farenc & Stephanie Gras
9/06/18
1 Media contribution
Press/Media: Article/Feature