Projects per year
Personal profile
Biography
Viruses are part of day-to-day encounters that the immune system needs to deal with. How the immune system recognises and eliminates viral infection is not fully understood. Indeed, viruses are able to mutate in order to escape the immune system surveillance. If we were to develop better vaccine and drugs, or even vaccine against viruses like HIV, it is essential to understand the mechanism of viral recognition and viral escape prior to this.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Immunology
- HLA
- T cell receptors
- influenza
- HIV
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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ALL IN - AI and Laboratory Led IdentificatioN of PASC
Short, K. R. (Primary Chief Investigator (PCI)), Gras, S. (Chief Investigator (CI)), Jacobson, K. (Chief Investigator (CI)), Trau, M. (Chief Investigator (CI)), Fraser, J. F. (Chief Investigator (CI)), Carney, M. (Chief Investigator (CI)), Eriksson, E. M. Y. (Chief Investigator (CI)), Suen, J. (Chief Investigator (CI)), Palpant, N. J. (Chief Investigator (CI)), Bindra, G. (Chief Investigator (CI)), Smith, C. (Chief Investigator (CI)), Chung Bernard Shiu, W. (Chief Investigator (CI)), Annesley, S. J. (Chief Investigator (CI)), D'Orsogna, L. J. (Chief Investigator (CI)) & Wuethrich, A. (Chief Investigator (CI))
1/01/24 → 31/12/25
Project: Research
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Defining the features of atypical T cell responses in Human Immunodeficiency Virus (HIV) controllers
Gras, S. (Primary Chief Investigator (PCI)), D'Orsogna, L. J. (Chief Investigator (CI)), Chakrabarti, L. (Associate Investigator (AI)), Lewin, S. (Associate Investigator (AI)), Grant, E. (Associate Investigator (AI)), Jacobson, K. (Associate Investigator (AI)) & Mackay, L. K. (Associate Investigator (AI))
1/01/23 → 31/12/26
Project: Research
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Epigenetic regulation of immune memory
Jacobson, K. (Primary Chief Investigator (PCI)) & Gras, S. (Chief Investigator (CI))
31/03/22 → 30/03/25
Project: Research
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Defining SARS-CoV-2 immune maintenance in the Australian population
Smith, C. (Primary Chief Investigator (PCI)), Gras, S. (Chief Investigator (CI)), Short, K. R. (Chief Investigator (CI)), Jacobson, K. (Chief Investigator (CI)), Hartel, G. (Chief Investigator (CI)), Barrett, H. L. (Chief Investigator (CI)) & Kitchener, S. (Chief Investigator (CI))
Department of Health and Aged Care (Australia)
1/11/20 → 1/11/22
Project: Research
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Beckman Coulter Optima Analytical Ultracentrifuge (AUC)
Dunstone, M. (Primary Chief Investigator (PCI)), Whisstock, J. (Chief Investigator (CI)), Daly, R. (Chief Investigator (CI)), Atkinson, S. (Chief Investigator (CI)), Turner, S. (Chief Investigator (CI)), Lithgow, T. (Chief Investigator (CI)), Gras, S. (Chief Investigator (CI)), Stone, M. (Chief Investigator (CI)), Davidovich, C. (Chief Investigator (CI)), Rood, J. (Chief Investigator (CI)), Coulibaly, F. (Chief Investigator (CI)), Wilce, J. (Chief Investigator (CI)), Borg, N. (Chief Investigator (CI)), McGowan, S. (Chief Investigator (CI)), Buckle, A. (Chief Investigator (CI)), Elmlund, D. (Chief Investigator (CI)), Elmlund, H. (Chief Investigator (CI)), Belousoff, M. (Chief Investigator (CI)), Ellisdon, A. (Chief Investigator (CI)), Law, R. (Chief Investigator (CI)), Purcell, A. (Chief Investigator (CI)), Cryle, M. (Chief Investigator (CI)), Nold, M. (Chief Investigator (CI)), Nold, C. (Chief Investigator (CI)), Warr, C. (Chief Investigator (CI)), Johnson, T. (Chief Investigator (CI)), Henstridge, M. (Chief Investigator (CI)), Aguilar, M. (Chief Investigator (CI)), Stroud, D. (Chief Investigator (CI)) & Ryan, M. (Chief Investigator (CI))
1/12/16 → 31/12/17
Project: Research
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Detection of Lymphocytic Choriomeningitis Virus-Specific Memory B Cells Using Antigen Tetramers
Cooper, L., Szeto, C., Jayasinghe, D., Taylor, J. J., Gras, S. & Good-Jacobson, K. L., 2024, Memory B-Cells: Methods and Protocols. Good-Jacobson, K. L. (ed.). 1st ed. New York NY USA: Humana Press, p. 117-129 13 p. (Methods in Molecular Biology; vol. 2826).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
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Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection
Cooper, L. (Leading Author), Xu, H., Polmear, J., Kealy, L., Szeto, C., Pang, E. S., Gupta, M., Kirn, A., Taylor, J. J., Jackson, K. J. L., Broomfield, B. J., Nguyen, A., Gago da Graça, C., La Gruta, N., Utzschneider, D. T., Groom, J. R., Martelotto, L., Parish, I. A., O'Keeffe, M. & Scharer, C. D. & 2 others, , 14 May 2024, In: Immunity. 57, 5, p. 1037-1055.e6 25 p.Research output: Contribution to journal › Article › Research › peer-review
8 Citations (Scopus) -
CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms
Huang, S., Shahine, A., Cheng, T.-Y., Chen, Y.-L., Ng, S. W., Balaji, G. R., Farquhar, R., Gras, S., Hardman, C. S., Altman, J. D., Tahiri, N., Minnaard, A. J., Ogg, G. S., Mayfield, J. A., Rossjohn, J. & Moody, D. B., 12 Oct 2023, In: Cell. 186, 21, p. 4583-4596.e13 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access16 Citations (Scopus) -
Elevated BMI reduces the humoral response to SARS-CoV-2 infection
Tong, M. Z. W. (Leading Author), Sng, J. D. J., Carney, M., Cooper, L., Brown, S., Lineburg, K. E., Chew, K. Y., Collins, N., Ignacio, K., Airey, M., Burr, L., Joyce, B. A., Jayasinghe, D., McMillan, C. L. D., Muller, D. A., Adhikari, A., Gallo, L. A., Dorey, E. S., Barrett, H. L. & Gras, S. (Leading Author) & 3 others, , 2023, In: Clinical & Translational Immunology. 12, 12, 13 p., e1476.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Citations (Scopus) -
Robust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities
Zhang, W., Kedzierski, L., Chua, B. Y., Mayo, M., Lonzi, C., Rigas, V., Middleton, B. F., McQuilten, H. A., Rowntree, L. C., Allen, L. F., Purcell, R. A., Tan, H. X., Petersen, J., Chaurasia, P., Mordant, F., Pogorelyy, M. V., Minervina, A. A., Crawford, J. C., Perkins, G. B. & Zhang, E. & 26 others, , Jun 2023, In: Nature Immunology. 24, 6, p. 966-978 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access17 Citations (Scopus)
Prizes
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Georgina Sweet Awards for Women in Quantitative Biomedical Science
Gras, S. (Recipient), 2017
Prize: Prize (including medals and awards)
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Press/Media
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A “super” receptor that helps kill HIV infected cells
Farenc, C. & Gras, S.
9/06/18
1 Media contribution
Press/Media: Article/Feature