Projects per year
Personal profile
Biography
Viruses are part of day-to-day encounters that the immune system needs to deal with. How the immune system recognises and eliminates viral infection is not fully understood. Indeed, viruses are able to mutate in order to escape the immune system surveillance. If we were to develop better vaccine and drugs, or even vaccine against viruses like HIV, it is essential to understand the mechanism of viral recognition and viral escape prior to this.
Research area keywords
- Immunology
- HLA
- T cell receptors
- influenza
- HIV
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2013 2017
- 2 Finished
Beckman Coulter Optima Analytical Ultracentrifuge (AUC)
Dunstone, M., Whisstock, J., Daly, R., Atkinson, S., Turner, S., Lithgow, T., Gras, S., Stone, M., Davidovich, C., Rood, J., Coulibaly, F., Wilce, J., Borg, N., McGowan, S., Buckle, A., Elmlund, D., Elmlund, H., Belousoff, M., Ellisdon, A., Law, R., Purcell, A., Cryle, M., Nold, M., Nold, C., Warr, C., Johnson, T., Henstridge, M., Aguilar, M., Stroud, D. & Ryan, M.
1/12/16 → 31/12/17
Project: Research
Research Output 2005 2019
Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation
Lim Kam Sian, T. C. C., Indumathy, S., Halim, H., Greule, A., Cryle, M. J., Bowness, P., Rossjohn, J., Gras, S., Purcell, A. W. & Schittenhelm, R. B., 27 Dec 2019, In : Journal of Biological Chemistry. 294, 52, p. 20185-20195 11 p.Research output: Contribution to journal › Article › Research › peer-review
3
Citations
(Scopus)
A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids
Shahine, A., Reinink, P., Reijneveld, J. F., Gras, S., Holzheimer, M., Cheng, T. Y., Minnaard, A. J., Altman, J. D., Lenz, S., Prandi, J., Kubler-Kielb, J., Moody, D. B., Rossjohn, J. & Van Rhijn, I., 4 Jan 2019, In : Nature Communications. 10, 1, 12 p., 56.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
A TCR β-chain motif biases toward recognition of human CD1 proteins
Reinink, P., Shahine, A., Gras, S., Cheng, T. Y., Farquhar, R., Lopez, K., Suliman, S. A., Reijneveld, J. F., Le Nours, J., Tan, L. L., León, S. R., Jimenez, J., Calderon, R., Lecca, L., Murray, M. B., Rossjohn, J., Moody, D. B. & Van Rhijn, I., 15 Dec 2019, In : Journal of Immunology. 203, 12, p. 3395-3406 12 p.Research output: Contribution to journal › Article › Research › peer-review
Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph
van de Sandt, C. E., Clemens, E. B., Grant, E. J., Rowntree, L. C., Sant, S., Halim, H., Crowe, J., Cheng, A. C., Kotsimbos, T. C., Richards, M., Miller, A., Tong, S. Y. C., Rossjohn, J., Nguyen, T. H. O., Gras, S., Chen, W. & Kedzierska, K., 6 Dec 2019, In : Nature Communications. 10, 1, 16 p., 5579.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
13
Citations
(Scopus)
Human CD8 + T cell cross-reactivity across influenza A, B and C viruses
Koutsakos, M., Illing, P. T., Nguyen, T. H. O., Mifsud, N. A., Crawford, J. C., Rizzetto, S., Eltahla, A. A., Clemens, E. B., Sant, S., Chua, B. Y., Wong, C. Y., Allen, E. K., Teng, D., Dash, P., Boyd, D. F., Grzelak, L., Zeng, W., Hurt, A. C., Barr, I., Rockman, S. & 17 others, , 18 Feb 2019, In : Nature Immunology. 20, p. 613-625 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Prizes
Dean's Award for Early Career
Stephanie Gras (Recipient), 2011
Prize: Prize (including medals and awards)
Georgina Sweet Awards for Women in Quantitative Biomedical Science
Stephanie Gras (Recipient), 2017
Prize: Prize (including medals and awards)
Press / Media
A “super” receptor that helps kill HIV infected cells
Carine Farenc & Stephanie Gras
9/06/18
1 Media contribution
Press/Media: Article/Feature