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Personal profile

Biography

Viruses are part of day-to-day encounters that the immune system needs to deal with. How the immune system recognises and eliminates viral infection is not fully understood. Indeed, viruses are able to mutate in order to escape the immune system surveillance. If we were to develop better vaccine and drugs, or even vaccine against viruses like HIV, it is essential to understand the mechanism of viral recognition and viral escape prior to this.

Research area keywords

  • Immunology
  • HLA
  • T cell receptors
  • influenza
  • HIV

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Projects 2013 2017

Research Output 2005 2019

1 Citation (Scopus)

A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids

Shahine, A., Reinink, P., Reijneveld, J. F., Gras, S., Holzheimer, M., Cheng, T. Y., Minnaard, A. J., Altman, J. D., Lenz, S., Prandi, J., Kubler-Kielb, J., Moody, D. B., Rossjohn, J. & Van Rhijn, I., 4 Jan 2019, In : Nature Communications. 10, 1, 12 p., 56.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
8 Citations (Scopus)

Human CD8 + T cell cross-reactivity across influenza A, B and C viruses

Koutsakos, M., Illing, P. T., Nguyen, T. H. O., Mifsud, N. A., Crawford, J. C., Rizzetto, S., Eltahla, A. A., Clemens, E. B., Sant, S., Chua, B. Y., Wong, C. Y., Allen, E. K., Teng, D., Dash, P., Boyd, D. F., Grzelak, L., Zeng, W., Hurt, A. C., Barr, I., Rockman, S. & 17 others, Jackson, D. C., Kotsimbos, T. C., Cheng, A. C., Richards, M., Westall, G. P., Loudovaris, T., Mannering, S. I., Elliott, M., Tangye, S. G., Wakim, L. M., Rossjohn, J., Vijaykrishna, D., Luciani, F., Thomas, P. G., Gras, S., Purcell, A. W. & Kedzierska, K., 18 Feb 2019, In : Nature Immunology. 20, p. 613-625 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
3 Citations (Scopus)

Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans

Grant, E. J., Josephs, T. M., Loh, L., Clemens, E. B., Sant, S., Bharadwaj, M., Chen, W., Rossjohn, J., Gras, S. & Kedzierska, K., 21 Dec 2018, In : Nature Communications. 9, 1, 16 p., 5427.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)

CD4+ T cell-mediated HLA class II cross-restriction in HIV controllers

Galperin, M., Farenc, C., Mukhopadhyay, M., Jayasinghe, D., Decroos, A., Benati, D., Tan, L. L., Ciacchi, L., Reid, H. H., Rossjohn, J., Chakrabarti, L. & Gras, S., 8 Jun 2018, In : Science Immunology. 3, 24, 13 p., eaat0687.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide

Chan, K. F., Gully, B. S., Gras, S., Beringer, D. X., Kjer-Nielsen, L., Cebon, J., McCluskey, J., Chen, W. & Rossjohn, J., 1 Dec 2018, In : Nature Communications. 9, 1, 13 p., 1026.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Prizes

ARC Future Fellowship

Stephanie Gras (Recipient), 2012

Prize: Competitive Fellowships

Dean's Award for Early Career

Stephanie Gras (Recipient), 2011

Prize: Prize (including medals and awards)

Georgina Sweet Awards for Women in Quantitative Biomedical Science

Stephanie Gras (Recipient), 2017

Prize: Prize (including medals and awards)

Monash Research Fellowship

Stephanie Gras (Recipient), 2011

Prize: Competitive Fellowships

Press / Media

A “super” receptor that helps kill HIV infected cells

Carine Farenc & Stephanie Gras

9/06/18

1 Media contribution

Press/Media: Article/Feature