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Personal profile

Biography

Viruses are part of day-to-day encounters that the immune system needs to deal with. How the immune system recognises and eliminates viral infection is not fully understood. Indeed, viruses are able to mutate in order to escape the immune system surveillance. If we were to develop better vaccine and drugs, or even vaccine against viruses like HIV, it is essential to understand the mechanism of viral recognition and viral escape prior to this.

Research area keywords

  • Immunology
  • HLA
  • T cell receptors
  • influenza
  • HIV

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2017

Research Output 2005 2019

Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation

Lim Kam Sian, T. C. C., Indumathy, S., Halim, H., Greule, A., Cryle, M. J., Bowness, P., Rossjohn, J., Gras, S., Purcell, A. W. & Schittenhelm, R. B., 27 Dec 2019, In : Journal of Biological Chemistry. 294, 52, p. 20185-20195 11 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids

Shahine, A., Reinink, P., Reijneveld, J. F., Gras, S., Holzheimer, M., Cheng, T. Y., Minnaard, A. J., Altman, J. D., Lenz, S., Prandi, J., Kubler-Kielb, J., Moody, D. B., Rossjohn, J. & Van Rhijn, I., 4 Jan 2019, In : Nature Communications. 10, 1, 12 p., 56.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

A TCR β-chain motif biases toward recognition of human CD1 proteins

Reinink, P., Shahine, A., Gras, S., Cheng, T. Y., Farquhar, R., Lopez, K., Suliman, S. A., Reijneveld, J. F., Le Nours, J., Tan, L. L., León, S. R., Jimenez, J., Calderon, R., Lecca, L., Murray, M. B., Rossjohn, J., Moody, D. B. & Van Rhijn, I., 15 Dec 2019, In : Journal of Immunology. 203, 12, p. 3395-3406 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph

van de Sandt, C. E., Clemens, E. B., Grant, E. J., Rowntree, L. C., Sant, S., Halim, H., Crowe, J., Cheng, A. C., Kotsimbos, T. C., Richards, M., Miller, A., Tong, S. Y. C., Rossjohn, J., Nguyen, T. H. O., Gras, S., Chen, W. & Kedzierska, K., 6 Dec 2019, In : Nature Communications. 10, 1, 16 p., 5579.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
13 Citations (Scopus)

Human CD8 + T cell cross-reactivity across influenza A, B and C viruses

Koutsakos, M., Illing, P. T., Nguyen, T. H. O., Mifsud, N. A., Crawford, J. C., Rizzetto, S., Eltahla, A. A., Clemens, E. B., Sant, S., Chua, B. Y., Wong, C. Y., Allen, E. K., Teng, D., Dash, P., Boyd, D. F., Grzelak, L., Zeng, W., Hurt, A. C., Barr, I., Rockman, S. & 17 others, Jackson, D. C., Kotsimbos, T. C., Cheng, A. C., Richards, M., Westall, G. P., Loudovaris, T., Mannering, S. I., Elliott, M., Tangye, S. G., Wakim, L. M., Rossjohn, J., Vijaykrishna, D., Luciani, F., Thomas, P. G., Gras, S., Purcell, A. W. & Kedzierska, K., 18 Feb 2019, In : Nature Immunology. 20, p. 613-625 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Prizes

ARC Future Fellowship

Stephanie Gras (Recipient), 2012

Prize: Competitive Fellowships

Dean's Award for Early Career

Stephanie Gras (Recipient), 2011

Prize: Prize (including medals and awards)

Georgina Sweet Awards for Women in Quantitative Biomedical Science

Stephanie Gras (Recipient), 2017

Prize: Prize (including medals and awards)

Monash Research Fellowship

Stephanie Gras (Recipient), 2011

Prize: Competitive Fellowships

Press / Media

A “super” receptor that helps kill HIV infected cells

Carine Farenc & Stephanie Gras

9/06/18

1 Media contribution

Press/Media: Article/Feature