1994 …2022
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Personal profile


I obtained my PhD in Statistics from Geneva University, Switzerland, in 1993, with my thesis involving methodological issues in robust inference. I started my biostatistician career at the Clinical Epidemiology Unit of Geneva University Hospital, followed by an experience in the pharmaceutical industry with Merck-Serono. I moved to Australia in 2002 to be appointed Senior Research Fellow at the NHMRC Clinical Trials Centre, Sydney University, gaining experience in biostatistical methodology, design and analyses of clinical trials and collaboration with clinicians. I was also involved in teaching for postgraduate students in biostatistics. In 2006, I joined the George Institute to work mainly on large-scale studies in cardiovascular and renal diseases, neurological and mental health, critical care and injury prevention. As Head of Statistical Research, I led an innovative statistical research program in clinical trial methodology and survival analysis. I became Associate Professor of biostatistics at the University of Sydney in 2009. In September 2014, I moved to Melbourne to become Associate Professor of Biostatistics at DEPM, Monash University. My research interests include adaptive designs, cluster randomised trials, robust methods in biostatistics, multistage disease modelling and penalised likelihood for survival data. I am a chief investigator on several NHMRC grants - 4 of them active - and am involved in statistical consulting within the Faculty of Medicine and for other institutions including the pharmaceutical industry. I am the lead author of a book entitled "Robust Methods in Biostatistics" published in 2009 with 3 Swiss coauthors.


Monash teaching commitment

BCA Master of Statistics, Linear models (LMR): main coordinator, semester 1

MPH5200, Regression methods for epidemiology: coordinator, semester 1

MPH5270, Advanced statistical methods for clinical research: coordinator, semester 2

Supervision interests

Clinical trial methodology, adaptive designs, robust biostatistics, survival analysis, cluster stepped-wedge/cross-over trials, joint modelling

External positions

Honorary Associate Professor of Biostatistics, The University of Sydney

21 Oct 201320 Oct 2016


  • Biostatistics
  • Clinical trial methodology
  • Adaptive designs
  • Cluster randomised trials
  • Robust statistics
  • Survival analysis
  • Semi-Markov processes
  • Stepped-wedge designs
  • Joint modelling
  • cluster cross-over trials

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2016 2022

Research Output 1994 2018

Age, age at diagnosis and diabetes duration are all associated with vascular complications in type 2 diabetes

Nanayakkara, N., Ranasinha, S., Gadowski, A., Flack, JR., Heritier, S., Wischer, N., Wong, J. & Zoungas, S., 1 Mar 2018, In : Journal of Diabetes and its Complications. 32, 3, p. 279-290 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Course and Contributors to Back Pain in Middle-aged Women Over 9 Years: Data From the Australian Longitudinal Study on Women's Health

Brady, S. R. E., Hussain, S. M., Brown, W. J., Heritier, S., Wang, Y., Teede, H., Urquhart, D. M. & Cicuttini, F. M., 1 Dec 2018, In : Spine. 43, 23, p. 1648-1656 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Efficacy of low-dose amitriptyline for chronic low back pain: A randomized clinical trial

Urquhart, D. M., Wluka, A. E., van Tulder, M., Heritier, S. R., Forbes, A. B., Fong, C. M. K., Wang, Y., Sim, M. R., Gibson, S. J., Arnold, C. A. & Cicuttini, F. M., Apr 2018, p. S416-S416. 1 p.

Research output: Contribution to conferenceAbstractOther

Impact of informed consent content and length on recruitment of older adults into a community based primary prevention trial

O'Hare, F., Spark, S., Flanagan, Z., Heritier, S., Curtis, A. & Zoungas, S., 1 Sep 2018, In : Contemporary Clinical Trials Communications. 11, p. 89-94 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Accurate p-values for adaptive designs with binary endpoints

Heritier, S., Lloyd, C. J. & Lô, S. N., May 2017, In : Statistics in Medicine. 36, 17, p. 2643-2655 13 p.

Research output: Contribution to journalArticleResearchpeer-review