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Research Output 2005 2019

1 Citation (Scopus)

A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis

van Delft, M. F., Chappaz, S., Khakham, Y., Bui, C. T., Debrincat, M. A., Lowes, K. N., Brouwer, J. M., Grohmann, C., Sharp, P. P., Dagley, L. F., Li, L., McArthur, K., Luo, M. X., Chin, H. S., Fairlie, W. D., Lee, E. F., Segal, D., Duflocq, S., Lessene, R., Bernard, S. & 16 others, Peilleron, L., Nguyen, T., Miles, C., Wan, S. S., Lane, R. M., Wardak, A., Lackovic, K., Colman, P. M., Sandow, J. J., Webb, A. I., Czabotar, P. E., Dewson, G., Watson, K. G., Huang, D. C. S., Lessene, G. & Kile, B. T., 1 Nov 2019, In : Nature Chemical Biology. 15, 11, p. 1057-1066 10 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Apoptosis in megakaryocytes and platelets: the life and death of a lineage

McArthur, K., Chappaz, S. & Kile, B. T., 8 Feb 2018, In : Blood. 131, 6, p. 605-610 6 p.

Research output: Contribution to journalArticleOtherpeer-review

68 Citations (Scopus)

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis

McArthur, K., Whitehead, L. W., Heddleston, J. M., Li, L., Padman, B. S., Oorschot, V., Geoghegan, N. D., Chappaz, S., Davidson, S., Chin, H. S., Lane, R. M., Dramicanin, M., Saunders, T. L., Sugiana, C., Lessene, R., Osellame, L. D., Chew, T. L., Dewson, G., Lazarou, M., Ramm, G. & 5 others, Lessene, G., Ryan, M. T., Rogers, K. L., Van Delft, M. F. & Kile, B. T., 23 Feb 2018, In : Science. 359, 6378, 12 p., eaao6047.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

VDAC2 enables BAX to mediate apoptosis and limit tumor development

Chin, H. S., Li, M. X., Tan, I. K. L., Ninnis, R. L., Reljic, B., Scicluna, K., Dagley, L. F., Sandow, J. J., Kelly, G. L., Samson, A. L., Chappaz, S., Khaw, S. L., Chang, C., Morokoff, A., Brinkmann, K., Webb, A., Hockings, C., Hall, C. M., Kueh, A. J., Ryan, M. T. & 7 others, Kluck, R. M., Bouillet, P., Herold, M. J., Gray, D. H. D., Huang, D. C. S., van Delft, M. F. & Dewson, G., 26 Nov 2018, In : Nature Communications. 9, 1, 13 p., 4976.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
17 Citations (Scopus)

Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia

Pleines, I., Woods, J., Chappaz, S., Kew, V., Foad, N., Ballester-Beltrán, J., Aurbach, K., Lincetto, C., Lane, R. M., Schevzov, G., Alexander, W. S., Hilton, D. J., Astle, W. J., Downes, K., Nurden, P., Westbury, S. K., Mumford, A. D., Obaji, S. G., Collins, P. W., BioResource, N. & 11 others, Delerue, F., Ittner, L. M., Bryce, N. S., Holliday, M., Lucas, C. A., Hardeman, E. C., Ouwehand, W. H., Gunning, P. W., Turro, E., Tijssen, M. R. & Kile, B. T., 1 Mar 2017, In : Journal of Clinical Investigation. 127, 3, p. 814-829 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access