Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 2 Active
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Inhibiting adenylate-forming enzymes via a new reaction-hijacking mechanism
Xie, S., Creek, D. & Owens, N.
Australian Research Council (ARC), Monash University – Internal School Contribution
25/09/23 → 24/09/26
Project: Research
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Hijacking enzymes that charge tRNAs: a new strategy for development of anti-malarials
Tilley, L. & Xie, S.
1/01/23 → 31/12/25
Project: Research
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Targeting Aminoacyl tRNA Synthetases for Antimalarial Drug Development
Xie, S. C., Griffin, M. D. W., Winzeler, E. A., Ribas De Pouplana, L. & Tilley, L., 15 Sept 2023, In: Annual Review of Microbiology. 77, p. 111-129 19 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access11 Citations (Scopus) -
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy
Xie, S. C., Metcalfe, R. D., Dunn, E., Morton, C. J., Huang, S. C., Puhalovich, T., Du, Y., Wittlin, S., Nie, S., Luth, M. R., Ma, L., Kim, M. S., Pasaje, C. F. A., Kumpornsin, K., Giannangelo, C., Houghton, F. J., Churchyard, A., Famodimu, M. T., Barry, D. C., Gillett, D. L., & 17 others, 3 Jun 2022, In: Science. 376, 6597, p. 1074-1079 6 p.Research output: Contribution to journal › Article › Research › peer-review
35 Citations (Scopus) -
Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome
Xie, S. C., Metcalfe, R. D., Mizutani, H., Puhalovich, T., Hanssen, E., Morton, C. J., Du, Y., Dogovski, C., Huang, S. C., Ciavarri, J., Hales, P., Griffin, R. J., Cohen, L. H., Chuang, B. C., Wittlin, S., Deni, I., Yeo, T., Ward, K. E., Barry, D. C., Liu, B., & 20 others, 21 Sept 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 39, 9 p., e2107213118.Research output: Contribution to journal › Article › Research › peer-review
Open Access26 Citations (Scopus) -
High Throughput Screening to Identify Selective and Nonpeptidomimetic Proteasome Inhibitors As Antimalarials
Mata-Cantero, L., Xie, S. C., García, M., Coyle, J., Fernandez, R., Cabrera, A. C., Gillett, D. L., Crespo, B., Gamo, F. J., Fernández, E., Tilley, L. & Gomez-Lorenzo, M. G., 11 Jun 2021, In: ACS Infectious Diseases. 7, 6, p. 1818-1832 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
K13, the Cytostome, and Artemisinin Resistance
Xie, S. C., Ralph, S. A. & Tilley, L., Jun 2020, In: Trends in Parasitology. 36, 6, p. 533-544 12 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access53 Citations (Scopus)