Sridurga Mithraprabhu

Dr

20062019

Research output per year

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Research Output

2019

DNA-repair gene mutations are highly prevalent in circulating tumour dna from multiple myeloma patients

Mithraprabhu, S., Hocking, J., Ramachandran, M., Choi, K., Klarica, D., Khong, T., Reynolds, J. & Spencer, A., 29 Jun 2019, In : Cancers. 11, 7, 14 p., 917.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Male age is associated with sperm DNA/chromatin integrity

Deenadayal Mettler, A., Govindarajan, M., Srinivas, S., Mithraprabhu, S., Evenson, D. & Mahendran, T., 1 Apr 2019, (Accepted/In press) In : The Aging Male. 8 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Monitoring tumour burden and therapeutic response through analysis of circulating tumour DNA and extracellular RNA in multiple myeloma patients

Mithraprabhu, S., Morley, R., Khong, T., Kalff, A., Bergin, K., Hocking, J., Savvidou, I., Bowen, K. M., Ramachandran, M., Choi, K., Wong, B. K. L., Reynolds, J. & Spencer, A., Aug 2019, In : Leukemia. 33, 8, p. 2022-2033 12 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Oral azacitidine (CC-486) in combination with lenalidomide and dexamethasone in advanced, lenalidomide-refractory multiple myeloma (ROAR study)

Kalff, A., Khong, T., Mithraprabhu, S., Bergin, K., Reynolds, J., Bowen, K. M., Thakurta, A., Guzman, R., Wang, M., Couto, S., Ren, Y. & Spencer, A., 29 Jul 2019, In : Leukemia and Lymphoma. 60, 9, p. 2143-2151 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Utility of circulating cell-free RNA analysis for the characterization of global transcriptome profiles of multiple myeloma patients

Chen, M., Mithraprabhu, S., Ramachandran, M., Choi, K., Khong, T. & Spencer, A., 1 Jun 2019, In : Cancers. 11, 6, 19 p., 887.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)
2018

Analysis of circulating tumor DNA

Mithraprabhu, S. & Spencer, A., 1 Jan 2018, Methods in Molecular Biology. Humana Press, p. 129-145 17 p. (Methods in Molecular Biology; vol. 1792).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2 Citations (Scopus)
7 Citations (Scopus)

Mining the plasma cell transcriptome for novel cell surface proteins

Trezise, S., Karnowski, A., Fedele, P. L., Mithraprabhu, S., Liao, Y., D’costa, K., Kueh, A. J., Hardy, M. P., Owczarek, C. M., Herold, M. J., Spencer, A., Shi, W., Willis, S. N., Nutt, S. L. & Corcoran, L. M., 1 Aug 2018, In : International Journal of Molecular Sciences. 19, 8, 2161.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

Preliminary Analysis of the Australasian Leukaemia and Lymphoma Group (ALLG) MM17 Trial: Response Adaptive Salvage Treatment with Carfilzomib-Thalidomide-Dexamethasone (KTd) for Newly Diagnosed Transplant Eligible Multiple Myeloma Patients Failing Front-Line Bortezomib-Based Induction Therapy: Blood 2018 132:3279

Spencer, A., Quach, H., Horvath, N., Kerridge, I. H., Yuen, F., Lee, E. S-H., Morris, E. S., Kalff, A., Bergin, K., Sirdesai, S., Gorniak, M., Mithraprabhu, S., Khong, T. & Reynolds, J., 29 Nov 2018, In : Blood. 132, Suppl 1, 1 p., 3279.

Research output: Contribution to journalMeeting AbstractOtherpeer-review

2017

Circulating tumour DNA analysis demonstrates spatial mutational heterogeneity that coincides with disease relapse in myeloma

Mithraprabhu, S., Khong, T., Ramachandran, M., Chow, A., Klarica, D., Mai, L., Walsh, S., Broemeling, D., Marziali, A., Wiggin, M., Hocking, J., Kalff, A., Durie, B. & Spencer, A., 1 Aug 2017, In : Leukemia. 31, 8, p. 1695-1705 11 p.

Research output: Contribution to journalArticleResearchpeer-review

43 Citations (Scopus)

Circulating tumour DNA analysis in multiple myeloma

Mithraprabhu, S. & Spencer, A., 1 Jan 2017, In : Oncotarget. 8, 53, p. 90610-90611 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

Open Access
2 Citations (Scopus)

Identification of Acetylation, Immune Cell Alterations and Gene Signature As Dynamic Biomarkers of Response to Panobinostat Treatment in Multiple Myeloma Patients

Mithraprabhu, S., Savvidou, I., Ramachandran, M., Kalff, A., Khong, T. T., Reed, K., Reynolds, J. & Spencer, A., 7 Dec 2017, In : Blood. 130, Suppl 1, 1 p., 1823.

Research output: Contribution to journalMeeting AbstractOtherpeer-review

2016

Epigenetics in the biology and treatment of multiple myeloma

Spencer, A. & Mithraprabhu, S., 2016, In : European Oncology & Haematology. 12, 2, p. 96-102 7 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
File

Heavy menstrual bleeding and dysmenorrhea are improved by magentic resonance guided focused ultrasound surgery (mrgfus) of adenomyosis

Jayaram, R., Subbarayan, K., Mithraprabhu, S. & Govindarajan, M., May 2016, In : Fertility Research and Practice. 2, 7 p., 8.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Liquid biopsies for liquid tumors: Emerging potential of circulating free nucleic acid evaluation for the management of hematologic malignancies

Hocking, J., Mithraprabhu, S., Kalff, A. & Spencer, A., 1 Jun 2016, In : Cancer Biology and Medicine. 13, 2, p. 215-225 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File
19 Citations (Scopus)

Roar: A Phase Ib Trial of Oral Azacitidine (CC-486) in Combination with Lenalidomide and Dexamethasone (Rd) for Patients with Relapsed and/or Refractory (R/R) Multiple Myeloma Who Have Failed a Prior Lenalidomide-Containing Regimen

Kalff, A., Reed, K., Khong, T. T., Mithraprabhu, S., Ramachandran, M., Reynolds, J., Bergin, K., Thakurta, A., Wang, M., Spencer, A., Guzman, R., Cuoto, S. & Ren, Y., 2 Dec 2016, In : Blood. 128, 22, 1 p., 2121.

Research output: Contribution to journalMeeting AbstractOtherpeer-review

TOP2A a New Predictive Marker of Response to Carfilzomib in Multiple Myeloma

Reale, A., Khong, T., Mithraprabhu, S., Reynolds, J., Ramachandran, M., Savvidou, I., Bergin, K., Hocking, J. & Spencer, A., 2 Dec 2016, In : Blood. 128, 22, 1 p., 4461.

Research output: Contribution to journalMeeting AbstractOtherpeer-review

2015

A rare case of IGH/MYC and IGH/BCL2 double hit primary plasma cell leukemia

Kalff, A., Khong, T., Wall, M., Gorniak, M., Mithraprabhu, S., Campbell, L. J. & Spencer, A., 2015, In : Haematologica: the hematology journal. 100, 2, p. e60-e62 3 p.

Research output: Contribution to journalLetterOtherpeer-review

Open Access
3 Citations (Scopus)

TOP2A knockdown resensitizes carfilzomib-resistant Hmcls to carfilzomib

Reale, A., Khong, T. T., Mithraprabhu, S., Savvidou, I., Ramachandran, M. & Spencer, A., Dec 2015, p. 4215. 1 p.

Research output: Contribution to conferenceAbstract

2014

Dual epigenetic targeting with panobinostat and azacitidine in acute myeloid leukemia and high-risk myelodysplastic syndrome

Tan, P., Wei, A., Mithraprabhu, S., Cummings, N. J., Liu, H. B., Perugini, M., Reed, K. D., Avery, S., Patil, S., Walker, P. A., Mollee, P. N., Grigg, A. P., D'Andrea, R. J., Dear, A. E. & Spencer, A., 2014, In : Blood Cancer Journal. 4, 1, p. 1 - 8 8 p., e170.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
70 Citations (Scopus)

Dysregulated Class I histone deacetylases are indicators of poor prognosis in multiple myeloma

Mithraprabhu, S., Kalff, A., Chow, A., Khong, T. T. F. & Spencer, A., 2014, In : Epigenetics. 9, 11, p. 1511 - 1520 10 p.

Research output: Contribution to journalArticleResearchpeer-review

62 Citations (Scopus)
Open Access
11 Citations (Scopus)
2013
26 Citations (Scopus)
2011

TCam-2 seminoma cell line exhibits characteristic foetal germ cell responses to TGF-beta ligands and retinoic acid

Young, J., Jaiprakash, A., Mithraprabhu, S., Itman, C., Kitazawa, R., Looijenga, L. & Loveland, K., 2011, In : International Journal of Andrology. 34, 4 (Part 2), p. e204 - e217 14 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)
2010

Activin bioactivity affects germ cell differentiation in the postnatal mouse testis in vivo

Mithraprabhu, S., Mendis, S. HS., Meachem, S. J., Tubino, L. M., Matzuk, M. M., Brown, C. W. & Loveland, K. A. L., 2010, In : Biology of Reproduction. 82, 5, p. 980 - 990 11 p.

Research output: Contribution to journalArticleResearchpeer-review

49 Citations (Scopus)

Deactylase inhibition in myeloproliferative neoplasms

Mithraprabhu, S., Grigoriadis, G., Khong, T. & Spencer, A., 2010, In : Investigational New Drugs. 28, Suppl 1, p. 50 - 57 8 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)
2009

Control of KIT signalling in male germ cells: What can we learn from other systems?

Mithraprabhu, S. & Loveland, K. A. L., 2009, In : Reproduction. 138, 5, p. 743 - 757 15 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)
2008

Activin regulates KIT mRNA and protein in the postnatal mouse testis: Biology of Reproduction

Loveland, K., Mithraprabhu, S., Barakat, B., Matzuk, M. & Brown, C., 2008, In : Biology of Reproduction. p. 130 1 p.

Research output: Contribution to journalArticleResearchpeer-review

2006

Expression of c-Kit receptor mRNA and protein in the developing, adult and irradiated rodent testis

Mithraprabhu, S., Meistrich, M. L., McLaughlin, E. A., Roman, S. D., Warne, S., Mendis, S. H. S., Itman, C. & Loveland, K. A. L., 2006, In : Reproduction. 131, 3, p. 489 - 499 11 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)

Expression of nuclear transport importins beta 1 and beta 3 is regulated during rodent spermatogenesis

Loveland, K. A. L., Hogarth, C., Szczepny, A., Mithra Prabhu, S. & Jans, D. A., 2006, In : Biology of Reproduction. 74, 28 September 2005, p. 67 - 74 7 p.

Research output: Contribution to journalArticleResearchpeer-review

40 Citations (Scopus)