Sofianos Andrikopoulos

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Research Output 2003 2019

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Article
2019

Four weeks of exercise early in life reprograms adult skeletal muscle insulin resistance caused by a paternal high-fat diet

Falcão-Tebas, F., Kuang, J., Arceri, C., Kerris, J. P., Andrikopoulos, S., Marin, E. C. & McConell, G. K., 1 Jan 2019, In : The Journal of Physiology. 597, 1, p. 121-136 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2018

Burden of cardiovascular risk factors and disease among patients with type 1 diabetes: Results of the Australian National Diabetes Audit (ANDA)

Pease, A., Earnest, A., Ranasinha, S., Nanayakkara, N., Liew, D., Wischer, N., Andrikopoulos, S. & Zoungas, S., 2 Jun 2018, In : Cardiovascular Diabetology. 17, 1, 12 p., 77.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Depression and diabetes distress in adults with type 2 diabetes: Results from the Australian National Diabetes Audit (ANDA) 2016

Nanayakkara, N., Pease, A., Ranasinha, S., Wischer, N., Andrikopoulos, S., Speight, J., De Courten, B. & Zoungas, S., 1 Dec 2018, In : Scientific Reports. 8, 1, 7846.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Insulin regulates POMC neuronal plasticity to control glucose metabolism

Dodd, G. T., Michael, N. J., Lee-Young, R. S., Mangiafico, S. P., Pryor, J. T., Munder, A. C., Simonds, S. E., Brüning, J. C., Zhang, Z-Y., Cowley, M. A., Andrikopoulos, S., Horvath, T. L., Spanswick, D. & Tiganis, T., 19 Sep 2018, In : eLife. 7, 30 p., e38704.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Probing the correlation between insulin activity and structural stability through introduction of the rigid A6 –A11 bond

Ong, S. C., Belgi, A., Van Lierop, B., Delaine, C., Andrikopoulos, S., MacRaild, C. A., Norton, R. S., Haworth, N. L., Robinson, A. J. & Forbes, B. E., 27 Jul 2018, In : Journal of Biological Chemistry. 293, 30, p. 11928-11943 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Risk-adjustment of diabetes health outcomes improves the accuracy of performance benchmarking

Danek, E., Earnest, A., Wischer, N., Andrikopoulos, S., Pease, A., Nanayakkara, N. & Zoungas, S., 1 Dec 2018, In : Scientific Reports. 8, 1, 11 p., 10261.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Younger people with Type 2 diabetes have poorer self-care practices compared with older people: results from the Australian National Diabetes Audit

Nanayakkara, N., Pease, A. J., Ranasinha, S., Wischer, N., Andrikopoulos, S., de Courten, B. & Zoungas, S., 1 Aug 2018, In : Diabetic Medicine. 35, 8, p. 1087-1095 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2017

Insulin in motion: The A6-A11 disulfide bond allosterically modulates structural transitions required for insulin activity

Van Lierop, B., Ong, S. C., Belgi, A., Delaine, C., Andrikopoulos, S., Haworth, N. L., Menting, J. G., Lawrence, M. C., Robinson, A. J. & Forbes, B. E., 1 Dec 2017, In : Scientific Reports. 7, 1, p. 1-14 14 p., 17239.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Metabolomic analysis of insulin resistance across different mouse strains and diets

Stöckli, J., Fisher-Wellman, K. H., Chaudhuri, R., Zeng, X. Y., Fazakerley, D. J., Meoli, C. C., Thomas, K. C., Hoffman, N. J., Mangiafico, S. P., Xirouchaki, C. E., Yang, C. H., Ilkayeva, O., Wong, K., Cooney, G. J., Andrikopoulos, S., Muoio, D. M. & James, D. E., 24 Nov 2017, In : Journal of Biological Chemistry. 292, 47, p. 19135-19145 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2016

Hepatocyte glutathione peroxidase-1 deficiency improves hepatic glucose metabolism and decreases steatohepatitis in mice

Merry, T. L., Tran, M., Dodd, G. T., Mangiafico, S. P., Wiede, F., Kaur, S., McLean, C. L., Andrikopoulos, S. & Tiganis, T., 1 Dec 2016, In : Diabetologia. 59, 12, p. 2632-2644 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Impaired glucose metabolism and exercise capacity with muscle-specific glycogen synthase 1 (gys1) deletion in adult mice

Xirouchaki, C. E., Mangiafico, S. P., Bate, K., Ruan, Z., Huang, A. M., Tedjosiswoyo, B. W., Lamont, B., Pong, W., Favaloro, J., Blair, A. R., Zajac, J. D., Proietto, J. & Andrikopoulos, S., 1 Mar 2016, In : Molecular Metabolism. 5, 3, p. 221-232 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Monotreme glucagon-like peptide-1 in venom and gut: one gene - two very different functions

Tsend-Ayush, E., He, C., Myers, M. A., Andrikopoulos, S., Wong, N., Sexton, P. M., Wootten, D., Forbes, B. E. & Grutzner, F., 29 Nov 2016, In : Scientific Reports. 6, 12 p., 37744.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2015

Ubiquitous expression of the Pik3caH1047R mutation promotes hypoglycemia, hypoinsulinemia, and organomegaly

Kinross, K. M., Montgomery, K. G., Mangiafico, S. P., Hare, L. M., Kleinschmidt, M., Bywater, M. J., Poulton, I. J., Vrahnas, C., Henneicke, H., Malaterre, J., Waring, P. M., Cullinane, C., Sims, N. A., McArthur, G. A., Andrikopoulos, S. & Phillips, W. A., Apr 2015, In : FASEB Journal. 29, 4, p. 1426-1434 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2014

Hepatic oxidative stress promotes insulin-STAT-5 signaling and obesity by inactivating protein tyrosine phosphatase N2

Gurzov, E., Tran, M., Fernandez-Rojo, M. A., Merry, T., Zhang, X., Wu, Y., Fukushima, A., Waters, M. J., Watt, M. J., Andrikopoulos, S., Neel, B. G. & Tiganis, T., 2014, In : Cell Metabolism. 20, 1, p. 85 - 102 18 p.

Research output: Contribution to journalArticleResearchpeer-review

High-fat-fed obese glutathione peroxidase 1-deficient mice exhibit defective insulin secretion but protection from hepatic steatosis and liver damage

Merry, T., Tran, M., Stathopoulos, M., Wiede, F., Fam, B. C., Dodd, G. T., Clarke, I. J., Watt, M. J., Andrikopoulos, S. & Tiganis, T., 2014, In : Antioxidants and Redox Signaling. 20, 14, p. 2114 - 2129 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Systemic VEGF-A neutralization ameliorates diet-induced metabolic dysfunction

Wu, L. E., Meoli, C. C., Mangiafico, S. P., Fazakerley, D. J., Cogger, V. C., Mohamad, M., Pant, H., Kang, M. J., Powter, E., Burchfield, J. G., Xirouchaki, C. E., Mikolaizak, A. S., Stöckli, J., Kolumam, G., Van Bruggen, N., Gamble, J. R., Le Couteur, D. G., Cooney, G. J., Andrikopoulos, S. & James, D. E., Aug 2014, In : Diabetes. 63, 8, p. 2656-2667 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2013

Glucose homeostasis can be differentially modulated by varying individual components of a western diet

Forbes, J. M., Cowan, S. P., Andrikopoulos, S., Morley, A. L., Ward, L. C., Walker, K. Z., Cooper, M. & Coughlan, M. T., 2013, In : Journal of Nutritional Biochemistry. 24, 7, p. 1251 - 1257 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2012

The role of liver fructose-1,6-bisphosphatase in regulating appetite and adiposity

Visinoni, S., Khalid, N. F. I., Joannides, C. N., Shulkes, A., Yim, M., Whitehead, J., Tiganis, T., Lamont, B., Favaloro, J. M., Proietto, J., Andrikopoulos, S. & Fam, B. C., 2012, In : Diabetes. 61, 5, p. 1122 - 1132 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2011

Advanced glycation end products are direct modulators of beta-cell function

Coughlan, M. T., Yap, F., Tong, D., Andrikopoulos, S., Gasser, A., Thallas-Bonke, V., Webster, D., Miyazaki, J., Kay, T., Slattery, R., Kaye, D., Drew, B., Kingwell, B., Fourlanos, S., Groop, P-H., Harrison, L., Knip, M. & Forbes, J., 2011, In : Diabetes. 60, 10, p. 2523 - 2532 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes

Forbes, J., Soderlund, J., Yap, F., Knip, M., Andrikopoulos, S., Ilonen, J., Simell, O., Veijola, R., Sourris, K., Coughlan, M. T., Forsblom, C., Slattery, R. M., Grey, S., Wessman, M., Yamamoto, H., Bierhaus, A., Cooper, M. & Groop, P., 2011, In : Diabetologia. 54, 5, p. 1032 - 1042 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Targeted reduction of advanced glycation improves renal function in obesity

Harcourt, B., Sourris, K., Coughlan, M. T., Walker, K., Dougherty, S., Andrikopoulos, S., Morley, A., Thallas-Bonke, V., Chand, V., Penfold, S., De Courten, M. P. J., Thomas, M., Kingwell, B., Bierhaus, A., Cooper, M., de Courten, B. & Forbes, J., 2011, In : Kidney International. 80, 2, p. 190 - 198 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2010

Disparate effects on renal and oxidative parameters following RAGE deletion, AGE accumulation inhibition, or dietary AGE control in experimental diabetic nephropathy

Tan, A., Sourris, K. C., Harcourt, B. E., Thallas-Bonke, V., Penfold, S. A., Andrikopoulos, S., Thomas, M. C., O'Brien, R. C., Bierhaus, A., Cooper, M., Forbes, J. M. & Coghlan, M. T., 2010, In : American Journal of Physiology - Renal Physiology. 298, 3, p. F763 - F770 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity

Sachithanandan, N., Fam, B. C., Fynch, S., Dzamko, N., Watt, M. J., Wormald, S., Honeyman, J., Galic, S., Proietto, J., Andrikopoulos, S., Hevener, A. L., Kay, T. WH. & Steinberg, G. R., 2010, In : Hepatology. 52, 5, p. 1632 - 1642 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Methods for enhancing ring closing metathesis yield in peptides: synthesis of a dicarba human growth hormone fragment

Van Lierop, B., Whelan, A., Andrikopoulos, S., Mulder, R., Jackson, W. & Robinson, A., 2010, In : International Journal of Peptide Research and Therapeutics. 16, 3, p. 133 - 144 12 p.

Research output: Contribution to journalArticleResearchpeer-review

T-cell protein tyrosine phosphatase attenuates STAT3 and insulin signaling in the liver to regulate gluconeogenesis

Fukushima, A., Loh, K., Galic, S., Fam, B., Shields, B., Wiede, F., Tremblay, M. L., Watt, M. J., Andrikopoulos, S. & Tiganis, T., 2010, In : Diabetes. 59, 8, p. 1906 - 1914 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2009

Reactive oxygen species enhance insulin sensitivity

Loh, K. Y., Deng, H., Fukushima, A., Cai, X., Boivin, B., Galic, S., Bruce, C., Shields, B. J., Skiba, B., Ooms, L. M., Stepto, N. K., Wu, B. J., Mitchell, C. A., Tonks, N. K., Watt, M. J., Febbraio, M. A., Crack, P. J., Andrikopoulos, S. & Tiganis, T., 2009, In : Cell Metabolism. 10, 4, p. 260 - 272 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Use of a temporary "solubilizing" peptide tag for the fmoc solid-phase synthesis of human insulin glargine via use of regioselective disulfide bond formation

Hossain, M. A., Belgi, A., Lin, F., Zhang, S., Shabanpoor, F., Chan, L., Belyea, C., Truong, H-T., Blair, A., Andrikopoulos, S., Tregear, G. W. & Wade, J. D., 2009, In : Bioconjugate Chemistry. 20, 7, p. 1390 - 1396 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2008

Increased glucose production in mice overexpressing human fructose-1,6-bisphosphatase in the liver

Visinoni, S., Fam, B. C., Blair, A., Rantzau, C., Lamont, B. J., Bouwman, R., Watt, M. J., Proietto, J., Favaloro, J. M. & Andrikopoulos, S., 2008, In : American Journal of Physiology - Endocrinology and Metabolism. 295, 5, p. E1132 - E1141 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2007

In vivo quantification of fat content in mice using the Hologic QDR 4500A densitometer

Senn, S. M., Kantor, S., Leury, B. J., Andrikopoulos, S., O'Brien, T. J., Morris, M. J., Proietto, J. & Wark, J. D., Jan 2007, In : Obesity Research and Clinical Practice. 1, 1, p. 69-77 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2006

Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice

Steinberg, G. R. R., Watt, M. J., Fam, B. C., Proietto, J., Andrikopoulos, S., Allen, A. M., Febbraio, M. A. A. & Kemp, B. E. E., 2006, In : Endocrinology. 147, 8, p. 3906 - 3914 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling

Steinberg, G. R., Michell, B. J., van Denderen, B. J. W. JW., Watt, M. J., Carey, A. L., Fam, B. C., Andrikopoulos, S., Proietto, J., Gorgun, C. Z., Carling, D., Hotamisligil, G. S., Febbraio, M. A., Kay, T. W. & Kemp, B. E. E., 2006, In : Cell Metabolism. 4, 6, p. 465 - 474 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2005

High glucose-induced impairment in insulin secretion is associated with reduction in islet glucokinase in a mouse model of susceptibility to islet dysfunction

Kooptiwut, S., Kebede, M., Zraika, S., Visinoni, S., Aston-Mourney, K., Favaloro, J., Tikellis, C., Thomas, M. C., Forbes, J. M., Cooper, M. E., Dunlop, M., Proietto, J. & Andrikopoulos, S., Aug 2005, In : Journal of Molecular Endocrinology. 35, 1, p. 39-48 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2004

Improved islet morphology following blockade of the renin angiotensin system in the Zucker diabetic fatty rat.

Tikellis, C., Wookey, P. J., Candido, R., Andrikopoulos, S., Thomas, M. C. & Cooper, M. E., 2004, In : Diabetes. 53, 4, p. 989-997 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2003

Interleukin-6 gene expression is increased in insulin-resistant rat skeletal muscle following insulin stimulation

Carey, A. L., Lamont, B., Andrikopoulos, S., Koukoulas, I., Proietto, J. & Febbraio, M. A., 21 Mar 2003, In : Biochemical and Biophysical Research Communications. 302, 4, p. 837-840 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Threshold effects of glucose transporter-4 (GLUT4) deficiency on cardiac glucose uptake and development of hypertrophy

Kaczmarczyk, S., Andrikopoulos, S., Favaloro, J., Domenighetti, A., Dunn, A., Ernst, M., Grail, D., Fodero-Tavoletti, M., Huggins, C., Delbridge, L., Zajac, J. & Proietto, J., 2003, In : Journal of Molecular Endocrinology. 31, 3, p. 449 - 459 11 p.

Research output: Contribution to journalArticleResearchpeer-review