Simon Royce

Dr

20002021
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Research Output 2000 2019

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Article
2019

Glycine microparticles loaded with functionalized nanoparticles for pulmonary delivery

Chakraborty, A., Royce, S. G., Plebanski, M. & Selomulya, C., 30 Oct 2019, In : International Journal of Pharmaceutics. 570, 9 p., 118654.

Research output: Contribution to journalArticleResearchpeer-review

Imbalance of the renin-angiotensin system may contribute to inflammation and fibrosis in IBD: Novel therapeutic target?

Garg, M., Royce, S. G., Tikellis, C., Shallue, C., Batu, D., Velkoska, E., Burrell, L. M., Patel, S. K., Beswick, L., Jackson, A., Britto, K., Lukies, M., Sluka, P., Wardan, H., Hirokawa, Y., Tan, C. W., Faux, M., Burgess, A. W., Hosking, P., Monagle, S. & 3 others, Thomas, M., Gibson, P. R. & Lubel, J., 13 Aug 2019, (Accepted/In press) In : Gut. 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Serelaxin enhances the therapeutic effects of human amnion epithelial cell-derived exosomes in experimental models of lung disease

Royce, S. G., Patel, K. P., Mao, W., Zhu, D., Lim, R. & Samuel, C. S., Jul 2019, In : British Journal of Pharmacology. 176, 13, p. 2195-2208 14 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)
Open Access
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2018
6 Citations (Scopus)

Hexarelin treatment preserves myocardial function and reduces cardiac fibrosis in mouse model of acute myocardial infarction

McDonald, H., Peart, J., Kurniawan, N., Galloway, G., Royce, S., Samuel, C. S. & Chen, C., 13 May 2018, In : Physiological Reports. 6, 9, 14 p., e13699.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2017
10 Citations (Scopus)
2016
12 Citations (Scopus)

Airway remodeling and hyperreactivity in a model of bronchopulmonary dysplasia and their modulation by IL-1Ra

Royce, S. G., Nold, M. F., Bui, C. B-Q., Donovan, C., Lam, M., Lamanna, E., Rudloff, I., Bourke, J. E. & Nold-Petry, C. A., 1 Dec 2016, In : American Journal of Respiratory Cell and Molecular Biology. 55, 6, p. 858-868 11 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)
30 Citations (Scopus)

A prospective open clinical trial of a proton pump inhibitor, elimination diet and/or budesonide for eosinophilic oesophagitis

Philpott, H., Nandurkar, S., Royce, S. G., Thien, F. & Gibson, P. R., 1 May 2016, In : Alimentary Pharmacology and Therapeutics. 43, 9, p. 985-993 9 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1

Hossain, M. A., Kocan, M., Yao, S. T., Royce, S. G., Nair, V. B., Siwek, C., Patil, N. A., Harrison, I. P., Rosengren, K. J., Selemidis, S., Summers, R. J., Wade, J. D., Bathgate, R. A. D. & Samuel, C. S., 2016, In : Chemical Science. 7, 6, p. 3805-3819 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
4 Citations (Scopus)

Combining an epithelial repair factor and anti-fibrotic with a corticosteroid offers optimal treatment for allergic airways disease

Patel, K. P., Giraud, A. S., Samuel, C. S. & Royce, S. G., 2016, In : British Journal of Pharmacology. 173, 12, p. 2016 - 2029 14 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Neonatal pneumococcal colonisation caused by Influenza A infection alters lung function in adult mice

FitzPatrick, M., Royce, S. G., Langenbach, S., McQualter, J., Reading, P. C., Wijburg, O., Anderson, G. P., Stewart, A., Bourke, J. & Bozinovski, S., 2016, In : Scientific Reports. 6, p. 1 - 12 12 p., 22751.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Serelaxin elicits bronchodilation and enhances β-Adrenoceptor-mediated airway relaxation

Lam, M., Royce, S. G., Donovan, C., Jelinic, M., Parry, L. J., Samuel, C. S. & Bourke, J. E., 27 Oct 2016, In : Frontiers in Pharmacology. 7, 406, 18 p., 406.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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5 Citations (Scopus)

Serelaxin improves the therapeutic efficacy of RXFP1-expressing human amnion epithelial cells in experimental allergic airway disease

Royce, S. G., Tominaga, A. M., Shen, M., Patel, K. P., Huuskes, B., Lim, R., Ricardo, S. D. & Samuel, C. S., 2016, In : Clinical Science. 130, 23, p. 2151-2165 15 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

The Coagulant Factor Xa Induces Protease-Activated Receptor-1 and Annexin A2–Dependent Airway Smooth Muscle Cytokine Production and Cell Proliferation

Schuliga, M., Royce, S. G., Langenbach, S., Berhan, A., Harris, T., Keenan, C. R. & Stewart, A. G., 2016, In : American Journal of Respiratory Cell and Molecular Biology. 54, 2, p. 200-209 10 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Ultrathin unsedated transnasal gastroscopy in monitoring eosinophilic esophagitis

Philpott, H., Nandurkar, S., Royce, S. G. & Gibson, P. R., 1 Mar 2016, In : Journal of Gastroenterology and Hepatology. 31, 3, p. 590-594 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2015
9 Citations (Scopus)

Alteration of airway reactivity and reduction of ryanodine receptor expression by cigarette smoke in mice

Donovan, C., Seow, H. J., Royce, S. G., Bourke, J. E. & Vlahos, R., 2015, In : American Journal of Respiratory Cell and Molecular Biology. 53, 4, p. 471 - 478 8 p.

Research output: Contribution to journalArticleResearchpeer-review

68 Citations (Scopus)

Dietary sulforaphane in cancer chemoprevention: the role of epigenetic regulation and HDAC inhibition

Tortorella, S., Royce, S. G., Licciardi, P. V. & Karagiannis, T. C., 2015, In : Antioxidants and Redox Signaling. 22, 16, p. 1382 - 1424 43 p.

Research output: Contribution to journalArticleResearchpeer-review

135 Citations (Scopus)

Electrophysiological, electroanatomical, and structural remodeling of the atria as consequences of sustained obesity

Mahajan, R., Lau, D. H., Brooks, A. G., Shipp, N. J., Manavis, J., Wood, J. P. M., Finnie, J. W., Samuel, C. S., Royce, S. G., Twomey, D. J., Thanigaimani, S., Kalman, J. M. & Sanders, P., 2015, In : Journal of the American College of Cardiology. 66, 1, p. 1 - 11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Eosinophilic esophagitis: A clinicopathological review

Philpott, H., Nandurkar, S., Thien, F., Gibson, P. R. & Royce, S. G., 2015, In : Pharmacology and Therapeutics. 146, p. 12 - 22 11 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Lipopolysaccharide does not alter small airway reactivity in mouse lung slices

Donovan, C., Royce, S. G., Vlahos, R. & Bourke, J. E., 2015, In : PLoS ONE. 10, 3, 16 p., e0122069.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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20 Citations (Scopus)

Mesenchymal stem cells and serelaxin synergistically abrogate established airway fibrosis in an experimental model of chronic allergic airways disease

Royce, S. G., Shen, M., Patel, K. P., Huuskes, B., Ricardo, S. D. & Samuel, C. S., 2015, In : Stem Cell Research. 15, 3, p. 495 - 505 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
9 Citations (Scopus)

Rosiglitazone elicits in vitro relaxation in airways and precision cut lung slices from a mouse model of chronic allergic airways disease

Donovan, C., Bailey, S. R., Tran, J., Haitsma, G., Ibrahim, Z. A., Foster, S. R., Tang, M. L. K., Royce, S. G. & Bourke, J. E., 2015, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 309, 10, p. 1219 - 1228 10 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Seasonal recurrence of food bolus obstruction in eosinophilic esophagitis

Philpott, H., Nandurkar, S., Thien, F. C. K., Bloom, S. D., Lin, E., Goldberg, R., Boyapati, R., Finch, A., Royce, S. G. & Gibson, P. R., 2015, In : Internal Medicine Journal. 45, 9, p. 939 - 943 5 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Characterization of a novel model incorporating airway epithelial damage and related fibrosis to the pathogenesis of asthma

Royce, S. G., Patel, K. P. & Samuel, C. S., 2014, In : Laboratory Investigation. 94, 12, p. 1326 - 1339 14 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)
20 Citations (Scopus)

Intranasally administered serelaxin abrogates airway remodelling and attenuates airway hyperresponsiveness in allergic airways disease

Royce, S. G., Lim, C., Patel, K. P., Wang, B., Samuel, C. S. & Tang, M. L. K., 2014, In : Clinical and Experimental Allergy. 44, 11, p. 1399 - 1408 10 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Mechanistic insights into the contribution of epithelial damage to airway remodeling. Novel therapeutic targets for asthma

Royce, S. G., Li, X., Tortorella, S., Goodings, L. M., Chow, B. SM., Giraud, A. S., Tang, M. L. K. & Samuel, C. S., 2014, In : American Journal of Respiratory Cell and Molecular Biology. 50, 1, p. 180 - 192 13 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)

Novel therapeutic strategies for lung disorders associated with airway remodelling and fibrosis

Royce, S. G., Moodley, Y. & Samuel, C. S., 2014, In : Pharmacology and Therapeutics. 141, 3, p. 250 - 260 11 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Risk factors for eosinophilic esophagitis

Philpott, H., Nandurkar, S., Royce, S. G., Thien, F. & Gibson, P. R., 2014, In : Clinical and Experimental Allergy. 44, 8, p. 1012 - 1019 8 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Role of caveolin-1 in asthma and chronic inflammatory respiratory diseases

Royce, S. G. & Le Saux, C. J., 2014, In : Expert Review of Respiratory Medicine. 8, 3, p. 339 - 347 9 p.

Research output: Contribution to journalArticleResearchpeer-review

47 Citations (Scopus)

Serelaxin is a more efficacious antifibrotic than enalapril in an experimental model of heart disease

Samuel, C. S., Bodaragama, H., Chew, J., Widdop, R. E., Royce, S. G. & Hewitson, T. D., 2014, In : Hypertension. 64, 2, p. 315 - 322 8 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

The effect of gas exchange on multiple-breath nitrogen washout measures of ventilation inhomogeneity in the mouse

Dharmakumara, M., Prisk, G. K., Royce, S. G., Tawhai, M. & Thompson, B. R., 2014, In : Journal of Applied Physiology. 117, 9, p. 1049 - 1054 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2013
14 Citations (Scopus)

Airway hyperresponsiveness is associated with airway remodeling but not inflammation in aging Cav1-/- mice

Gabehart, K. E., Royce, S. G., Maselli, D. J., Miyasato, S. K., Davis, E. C., Tang, M. L. K. & Jourdan Le Saux, C., 21 Oct 2013, In : Respiratory Research. 14, 1, p. 1-11 11 p., 110.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
14 Citations (Scopus)
18 Citations (Scopus)

Differential effects of allergen challenge on large and small airway reactivity in mice

Donovan, C., Royce, S. G., Esposito, J., Tran, J., Ibrahim, Z. A., Tang, M. L. K., Bailey, S. & Bourke, J. E., 6 Sep 2013, In : PLoS ONE. 8, 9, p. 1-8 8 p., e74101.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
160 Citations (Scopus)

Obesity results in progressive atrial structural and electrical remodeling: implications for atrial fibrillation

Abed, H. S., Samuel, C. S., Lau, D. H., Kelly, D. J., Royce, S. G., Alasady, M., Mahajan, R., Kuklik, P., Zhang, Y. M., Brooks, A. G., Nelson, A. J., Worthley, S. G., Abhayaratna, W., Kalman, J., Wittert, G. G. & Sanders, P., 2013, In : Heart Rhythm. 10, 1, p. 90 - 100 11 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Plasminogen-stimulated airway smooth muscle cell proliferation is mediated by urokinase and annexin A2, involving plasmin-activated cell signalling

Stewart, A. G., Xia, Y., Harris, T., Royce, S., Hamilton, J. A. & Schuliga, M., Dec 2013, In : British Journal of Pharmacology. 170, 7, p. 1421-1435 15 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Trefoil factor-2 reverses airway remodeling changes in allergic airways disease

Royce, S. G., Lim, C., Muljadi, R. C. M., Samuel, C. S., Ververis, K., Karagiannis, T. C., Giraud, A. S. & Tang, M. LK., 2013, In : American Journal of Respiratory Cell and Molecular Biology. 48, 1, p. 135 - 144 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2012

Controversies surrounding the potential use of histone deacetylase Inhibitors for the treatment of asthma

Royce, S. G., Ververis, K. & Karagiannis, T. C., 2012, In : ISRN Pulmonology. 2012, 10 p., 452307.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
File
15 Citations (Scopus)

Effects of the histone deacetylase inhibitor, trichostatin A, in a chronic allergic airways disease model in mice

Royce, S. G., Dang, W., Yuan, G. Y., Tran, J., El-Osta, A., Karagiannis, T. & Tang, M. L. K., Aug 2012, In : Archivum Immunologiae et Therapiae Experimentalis. 60, 4, p. 295-306 12 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)
15 Citations (Scopus)

Histone deacetylases and their role in asthma

Royce, S. G. & Karagiannis, T. C., 2012, In : Journal of Asthma. 49, 2, p. 121 - 128 8 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Molecular model of naphthalene-induced DNA damage in the murine lung

Karagiannis, T. C., Li, X., Tang, M. M., Orlowski, C., El-Osta, A., Tang, M. L. K. & Royce, S. G., 2012, In : Human and Experimental Toxicology. 31, 1, p. 42-50 9 p.

Research output: Contribution to journalArticleResearchpeer-review

57 Citations (Scopus)

The regulation of fibrosis in airway remodeling in asthma

Royce, S. G., Cheng, V., Samuel, C. & Tang, M. L. K., 2012, In : Molecular and Cellular Endocrinology. 351, 2, p. 167 - 175 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2011
12 Citations (Scopus)

Protective effects of valproic acid against airway hyperresponsiveness and airway remodeling in a mouse model of allergic airways disease

Royce, S. G., Dang, W., Ververis, K., De Sampayo, N., El-Osta, A., Tang, M. L. K. & Karagiannis, T. C., Dec 2011, In : Epigenetics. 6, 12, p. 1463 - 1470 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Resveratrol has protective effects against airway remodeling and airway hyperreactivity in a murine model of allergic airways disease

Royce, S. G., Dang, W., Yuan, G. Y., Tran, J., El-Osta, A., Karagiannis, T. & Tang, M. LK., 2011, In : Pathobiology of Aging & Age-related Diseases. 1, 10 p., 7134.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)

Trefoil factor 2 regulates airway remodeling in animal models of asthma

Royce, S. G., Lim, C., Muljadi, R. C. M. & Tang, M. LK., 2011, In : Journal of Asthma. 48, 7, p. 653 - 659 7 p.

Research output: Contribution to journalArticleResearchpeer-review