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Research Output 2000 2019

Article
14 Citations (Scopus)

Age and sex influences on airway hyperresponsiveness

McKenzie, R., Burton, M., Royce, S. G. & Tang, M. LK., 2010, In : Journal of Asthma. 47, 6, p. 651 - 654 4 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Airway hyperresponsiveness is associated with airway remodeling but not inflammation in aging Cav1-/- mice

Gabehart, K. E., Royce, S. G., Maselli, D. J., Miyasato, S. K., Davis, E. C., Tang, M. L. K. & Jourdan Le Saux, C., 21 Oct 2013, In : Respiratory Research. 14, 1, p. 1-11 11 p., 110.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
12 Citations (Scopus)

Airway remodeling and hyperreactivity in a model of bronchopulmonary dysplasia and their modulation by IL-1Ra

Royce, S. G., Nold, M. F., Bui, C. B-Q., Donovan, C., Lam, M., Lamanna, E., Rudloff, I., Bourke, J. E. & Nold-Petry, C. A., 1 Dec 2016, In : American Journal of Respiratory Cell and Molecular Biology. 55, 6, p. 858-868 11 p.

Research output: Contribution to journalArticleResearchpeer-review

73 Citations (Scopus)

Airway remodelling in asthma: Current understanding and implications for future therapies

Tang, M. L. K., Wilson, J. W., Stewart, A. G. & Royce, S. G., Nov 2006, In : Pharmacology and Therapeutics. 112, 2, p. 474 - 488 15 p.

Research output: Contribution to journalArticleOtherpeer-review

30 Citations (Scopus)
9 Citations (Scopus)

Alteration of airway reactivity and reduction of ryanodine receptor expression by cigarette smoke in mice

Donovan, C., Seow, H. J., Royce, S. G., Bourke, J. E. & Vlahos, R., 2015, In : American Journal of Respiratory Cell and Molecular Biology. 53, 4, p. 471 - 478 8 p.

Research output: Contribution to journalArticleResearchpeer-review

A novel foregut mucin characterized by a murine monoclonal autoantibody

Binos, S., Royce, S. G., Oxley, D., Bacic, A., Bhathal, P. S. & Underwood, J. R., 2010, In : Hybridoma. 29, 2, p. 87 - 101 15 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

A prospective open clinical trial of a proton pump inhibitor, elimination diet and/or budesonide for eosinophilic oesophagitis

Philpott, H., Nandurkar, S., Royce, S. G., Thien, F. & Gibson, P. R., 1 May 2016, In : Alimentary Pharmacology and Therapeutics. 43, 9, p. 985-993 9 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1

Hossain, M. A., Kocan, M., Yao, S. T., Royce, S. G., Nair, V. B., Siwek, C., Patil, N. A., Harrison, I. P., Rosengren, K. J., Selemidis, S., Summers, R. J., Wade, J. D., Bathgate, R. A. D. & Samuel, C. S., 2016, In : Chemical Science. 7, 6, p. 3805-3819 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
1 Citation (Scopus)

Attenuated methacholine airway response following repeat testing in a murine model of allergic airways disease

McKenzie, R., Royce, S. G., Burton, M. D. & Tang, M. L. K., Jun 2008, In : Experimental Lung Research. 34, 5, p. 277-286 10 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

BRCA1 promoter deletions in young women with breast cancer and a strong family history: A population-based study

Smith, L. D., Tesoriero, A. A., Ramus, S. J., Dite, G., Royce, S. G., Giles, G. G., McCredie, M. R. E., Hopper, J. L. & Southey, M. C., Mar 2007, In : European Journal of Cancer. 43, 5, p. 823-827 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Cell cycle effects of L-sulforaphane, a major antioxidant from cruciferous vegetables: The role of the anaphase promoting complex

Li, Z. S., Royce, S. G., Ververis, K. & Karagiannis, T. C., 2014, In : Hellenic Journal of Nuclear Medicine. 17, p. 11-16 6 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Characterization of a novel model incorporating airway epithelial damage and related fibrosis to the pathogenesis of asthma

Royce, S. G., Patel, K. P. & Samuel, C. S., 2014, In : Laboratory Investigation. 94, 12, p. 1326 - 1339 14 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)
4 Citations (Scopus)

Combining an epithelial repair factor and anti-fibrotic with a corticosteroid offers optimal treatment for allergic airways disease

Patel, K. P., Giraud, A. S., Samuel, C. S. & Royce, S. G., 2016, In : British Journal of Pharmacology. 173, 12, p. 2016 - 2029 14 p.

Research output: Contribution to journalArticleResearchpeer-review

109 Citations (Scopus)

Comparison of airway remodeling in acute, subacute, and chronic models of allergic airways disease

Locke, N., Royce, S., Wainewright, J., Samuel, C. & Tang, M., 2007, In : American Journal of Respiratory Cell and Molecular Biology. 36, 5, p. 625 - 632 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Controversies surrounding the potential use of histone deacetylase Inhibitors for the treatment of asthma

Royce, S. G., Ververis, K. & Karagiannis, T. C., 2012, In : ISRN Pulmonology. 2012, 10 p., 452307.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
File
65 Citations (Scopus)

Dietary sulforaphane in cancer chemoprevention: the role of epigenetic regulation and HDAC inhibition

Tortorella, S., Royce, S. G., Licciardi, P. V. & Karagiannis, T. C., 2015, In : Antioxidants and Redox Signaling. 22, 16, p. 1382 - 1424 43 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Differential effects of allergen challenge on large and small airway reactivity in mice

Donovan, C., Royce, S. G., Esposito, J., Tran, J., Ibrahim, Z. A., Tang, M. L. K., Bailey, S. & Bourke, J. E., 6 Sep 2013, In : PLoS ONE. 8, 9, p. 1-8 8 p., e74101.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
29 Citations (Scopus)

Effect of extracellular matrix composition on airway epithelial cell and fibroblast structure: implications for airway remodeling in asthma

Royce, S. G., Tan, L., Koek, A. A. & Tang, M. LK., 2009, In : Annals of Allergy, Asthma and Immunology. 102, 3, p. 238 - 246 9 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Effects of the histone deacetylase inhibitor, trichostatin A, in a chronic allergic airways disease model in mice

Royce, S. G., Dang, W., Yuan, G. Y., Tran, J., El-Osta, A., Karagiannis, T. & Tang, M. L. K., Aug 2012, In : Archivum Immunologiae et Therapiae Experimentalis. 60, 4, p. 295-306 12 p.

Research output: Contribution to journalArticleResearchpeer-review

133 Citations (Scopus)

Electrophysiological, electroanatomical, and structural remodeling of the atria as consequences of sustained obesity

Mahajan, R., Lau, D. H., Brooks, A. G., Shipp, N. J., Manavis, J., Wood, J. P. M., Finnie, J. W., Samuel, C. S., Royce, S. G., Twomey, D. J., Thanigaimani, S., Kalman, J. M. & Sanders, P., 2015, In : Journal of the American College of Cardiology. 66, 1, p. 1 - 11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

48 Citations (Scopus)

Endogenous relaxin regulates collagen deposition in an animal model of allergic airway disease

Mookerjee, I., Solly, N., Royce, S., Tregear, G., Samuel, C. & Tang, M., 2006, In : Endocrinology. 147, 2, p. 754 - 761 8 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Eosinophilic esophagitis: A clinicopathological review

Philpott, H., Nandurkar, S., Thien, F., Gibson, P. R. & Royce, S. G., 2015, In : Pharmacology and Therapeutics. 146, p. 12 - 22 11 p.

Research output: Contribution to journalArticleResearchpeer-review

78 Citations (Scopus)

Ethnicity and risk for colorectal cancers showing somatic BRAF V600E mutation or CpG island methylator phenotype

English, D. R., Young, J. P., Simpson, J. A., Jenkins, M. A., Southey, M. C., Walsh, M. D., Buchanan, D. D., Barker, M. A., Haydon, A. M., Royce, S. G., Roberts, A., Parry, S., Hopper, J., Jass, J. J. & Giles, G. G., Jul 2008, In : Cancer Epidemiology Biomarkers and Prevention. 17, 7, p. 1774-1780 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Glycine microparticles loaded with functionalized nanoparticles for pulmonary delivery

Chakraborty, A., Royce, S. G., Plebanski, M. & Selomulya, C., 30 Oct 2019, In : International Journal of Pharmaceutics. 570, 9 p., 118654.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Hexarelin treatment preserves myocardial function and reduces cardiac fibrosis in mouse model of acute myocardial infarction

McDonald, H., Peart, J., Kurniawan, N., Galloway, G., Royce, S., Samuel, C. S. & Chen, C., 13 May 2018, In : Physiological Reports. 6, 9, 14 p., e13699.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
10 Citations (Scopus)

Histone deacetylase inhibitors: can we consider potent anti-neoplastic agents for the treatment of asthma?

Royce, S. G., Ververis, K. & Karagiannis, T. C., 2012, In : Annals of Clinical and Laboratory Science. 42, 3, p. 338-345 8 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)
15 Citations (Scopus)

Histone deacetylases and their role in asthma

Royce, S. G. & Karagiannis, T. C., 2012, In : Journal of Asthma. 49, 2, p. 121 - 128 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Imbalance of the renin-angiotensin system may contribute to inflammation and fibrosis in IBD: Novel therapeutic target?

Garg, M., Royce, S. G., Tikellis, C., Shallue, C., Batu, D., Velkoska, E., Burrell, L. M., Patel, S. K., Beswick, L., Jackson, A., Britto, K., Lukies, M., Sluka, P., Wardan, H., Hirokawa, Y., Tan, C. W., Faux, M., Burgess, A. W., Hosking, P., Monagle, S. & 3 others, Thomas, M., Gibson, P. R. & Lubel, J., 13 Aug 2019, (Accepted/In press) In : Gut. 11 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)
20 Citations (Scopus)

Intranasally administered serelaxin abrogates airway remodelling and attenuates airway hyperresponsiveness in allergic airways disease

Royce, S. G., Lim, C., Patel, K. P., Wang, B., Samuel, C. S. & Tang, M. L. K., 2014, In : Clinical and Experimental Allergy. 44, 11, p. 1399 - 1408 10 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Lipopolysaccharide does not alter small airway reactivity in mouse lung slices

Donovan, C., Royce, S. G., Vlahos, R. & Bourke, J. E., 2015, In : PLoS ONE. 10, 3, 16 p., e0122069.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
25 Citations (Scopus)
20 Citations (Scopus)

Low somatic K-ras mutation frequency in colorectal cancer diagnosed under the age of 45 years

Alsop, K., Mead, L., Smith, L., Royce, S. G., Tesoriero, A. A., Young, J. P., Haydon, A. M., Grubb, G., Giles, G. G., Jenkins, M. A., Hopper, J. & Southey, M. C., 2006, In : European Journal of Cancer. 42, 10, p. 1357 - 1361 5 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Mechanistic insights into the contribution of epithelial damage to airway remodeling. Novel therapeutic targets for asthma

Royce, S. G., Li, X., Tortorella, S., Goodings, L. M., Chow, B. SM., Giraud, A. S., Tang, M. L. K. & Samuel, C. S., 2014, In : American Journal of Respiratory Cell and Molecular Biology. 50, 1, p. 180 - 192 13 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Mesenchymal stem cells and serelaxin synergistically abrogate established airway fibrosis in an experimental model of chronic allergic airways disease

Royce, S. G., Shen, M., Patel, K. P., Huuskes, B., Ricardo, S. D. & Samuel, C. S., 2015, In : Stem Cell Research. 15, 3, p. 495 - 505 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
25 Citations (Scopus)

Microsatellite instability markers for identifying early-onset colorectal cancers caused by germ-line mutations in DNA mismatch repair genes

Mead, L. J., Jenkins, M. A., Young, J., Royce, S. G., Smith, L., St. John, D. J. B., Macrae, F., Giles, G. G., Hopper, J. L. & Southey, M. C., 15 May 2007, In : Clinical Cancer Research. 13, 10, p. 2865-2869 5 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Molecular model of naphthalene-induced DNA damage in the murine lung

Karagiannis, T. C., Li, X., Tang, M. M., Orlowski, C., El-Osta, A., Tang, M. L. K. & Royce, S. G., 2012, In : Human and Experimental Toxicology. 31, 1, p. 42-50 9 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Neonatal pneumococcal colonisation caused by Influenza A infection alters lung function in adult mice

FitzPatrick, M., Royce, S. G., Langenbach, S., McQualter, J., Reading, P. C., Wijburg, O., Anderson, G. P., Stewart, A., Bourke, J. & Bozinovski, S., 2016, In : Scientific Reports. 6, p. 1 - 12 12 p., 22751.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
32 Citations (Scopus)

Novel therapeutic strategies for lung disorders associated with airway remodelling and fibrosis

Royce, S. G., Moodley, Y. & Samuel, C. S., 2014, In : Pharmacology and Therapeutics. 141, 3, p. 250 - 260 11 p.

Research output: Contribution to journalArticleResearchpeer-review

158 Citations (Scopus)

Obesity results in progressive atrial structural and electrical remodeling: implications for atrial fibrillation

Abed, H. S., Samuel, C. S., Lau, D. H., Kelly, D. J., Royce, S. G., Alasady, M., Mahajan, R., Kuklik, P., Zhang, Y. M., Brooks, A. G., Nelson, A. J., Worthley, S. G., Abhayaratna, W., Kalman, J., Wittert, G. G. & Sanders, P., 2013, In : Heart Rhythm. 10, 1, p. 90 - 100 11 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Plasminogen-stimulated airway smooth muscle cell proliferation is mediated by urokinase and annexin A2, involving plasmin-activated cell signalling

Stewart, A. G., Xia, Y., Harris, T., Royce, S., Hamilton, J. A. & Schuliga, M., Dec 2013, In : British Journal of Pharmacology. 170, 7, p. 1421-1435 15 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Protective effects of valproic acid against airway hyperresponsiveness and airway remodeling in a mouse model of allergic airways disease

Royce, S. G., Dang, W., Ververis, K., De Sampayo, N., El-Osta, A., Tang, M. L. K. & Karagiannis, T. C., Dec 2011, In : Epigenetics. 6, 12, p. 1463 - 1470 8 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Quantitation of gammaH2AX Foci in Tissue Samples

Tang, M. M., Mah, L-J., Vasireddy, R. S., Georgiadis, G. T., El-Osta, A., Royce, S. G. & Karagiannis, T., 2010, In : Journal of Visualized Experiments. 2010, 40, p. 1 - 3 3 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Relaxin family peptide receptor-1 protects against airway fibrosis during homeostasis but not against fibrosis associated with chronic allergic airways disease

Samuel, C., Royce, S., Cheng, B., Cao, H., Gossen, J., Tregear, G. & Tang, M., 2009, In : Endocrinology. 150, 3, p. 1495 - 1502 8 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Relaxin plays an important role in the regulation of airway structure and function

Samuel, C., Royce, S., Burton, M., Zhao, C., Tregear, G. & Tang, M., 2007, In : Endocrinology. 148, 9, p. 4259 - 4266 8 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Relaxin reverses airway remodeling and airway dysfunction in allergic airways disease

Royce, S., Miao, Y., Lee, M., Samuel, C., Tregear, G. & Tang, M., 2009, In : Endocrinology. 150, 6, p. 2692 - 2699 8 p.

Research output: Contribution to journalArticleResearchpeer-review